Assessment of pathologic response after preoperative chemoradiotherapy and surgery in pancreatic adenocarcinoma

International Journal of Radiation Oncology Biology Physics

Volumn 60, Issue 2, 2004, Pages 437-443

  Moutardier, Vincent ^a   Magnin, Valérie ^a   Turrini, Olivier ^a   Viret, Frédéric ^a   Hennekinne Mucci, Stephanie ^a   Gonçalves, Antony ^a   Pesenti, Christian ^a   Guiramand, Jérome ^a   Lelong, Bernard ^a   Giovannini, Marc ^a   Monges, Geneviève ^a   Houvenaeghel, Gilles ^a   Delpero, Jean Robert ^a  

^a INSTITUT PAOLI CALMETTES   (France)

Author keywords

Pancreatic adenocarcinoma; Pathologic response; Preoperative chemoradiotherapy; Surgical resection

Indexed keywords

DISEASES; PATIENT MONITORING; PATIENT TREATMENT; RADIATION EFFECTS; RADIOTHERAPY; SURGERY; TUMORS;

CHEMORADIOTHERAPY (CRT); PANCREAS; PANCREATIC DUCTULAR ADENOCARCINOMA (PDA);

PATHOLOGY;

ADULT; AGED; ARTICLE; CANCER GROWTH; CANCER SURVIVAL; DIARRHEA; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; NAUSEA; PANCREAS ADENOCARCINOMA; PANCREAS DUCT; PANCREAS RESECTION; PANCREATICODUODENECTOMY; PREOPERATIVE PERIOD; PREOPERATIVE RADIOTHERAPY; PRIORITY JOURNAL; STOMATITIS; TREATMENT OUTCOME; VOMITING;

ADULT; AGED; CARCINOMA, PANCREATIC DUCTAL; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; MALE; MIDDLE AGED; NEOPLASM STAGING; PANCREATECTOMY; PANCREATIC NEOPLASMS; PANCREATICODUODENECTOMY; RETROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 4544257275     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2004.04.004     Document Type: Article

References (28)

1. Snady H., Bruckner H., Cooperman A., et al. Survival advantage of combined chemoradiotherapy compared with resection as the initial treatment of patients with regional pancreatic carcinoma. Cancer. 89:2000;316-327
2. Du W., Touchette D., Vaitkevicious V.K., et al. Cost analysis of pancreatic carcinoma treatment. Cancer. 89:2000;1917-1924
3. Gastrointestinal Tumor Study Group. Further evidence of effective adjuvant combined radiation and chemotherapy following curative resection of pancreatic cancer. Cancer. 59:1987;2006-2010
4. Neoptolemos J.P., Dunn J.A., Stocken D.D., et al. European Study Group for Pancreatic Cancer. Adjuvant chemoradiotherapy and chemotherapy in resectable pancreatic cancer A randomised controlled trial. Lancet. 358:2001;1576-1585
5. Spitz F.R., Abbruzzese J.L., Lee J.E., et al. Preoperative and postoperative chemoradiation strategies in patients treated with pancreaticoduodenectomy for adenocarcinoma of the pancreas. J Clin Oncol. 15:1997;928-937
6. Hoffman J.P., Lipsitz S., Pisansky T., et al. Phase II trial of preoperative radiation therapy and chemotherapy for patients with localized resectable adenocarcinoma of the pancreas An Eastern Cooperative Oncology Group study. J Clin Oncol. 16:1998;317-323
7. White R.R., Hurwitz H.I., Morse M.A., et al. Neoadjuvant chemoradiation for localized adenocarcinoma of the pancreas. Ann Surg Oncol. 8:2001;758-765
8. Coia L., Hoffman J., Scher R., et al. Preoperative chemoradiation for adenocarcinoma of the pancreas and duodenum. Int J Radiat Oncol Biol Phys. 30:1994;161-167
9. Wayne J.D., Abdalla E.K., Wolff R.A., et al. Localized adenocarcinoma of the pancreas The rationale for preoperative chemoradiation. Oncologist. 7:2002;34-45
10. Magnin V., Moutardier V., Giovannini M.H., et al. Neoadjuvant preoperative chemoradiation in patients with pancreatic cancer. Int J Radiat Oncol Biol Phys. 55:2003;1300-1304
11. Wolff R.A. Neoadjuvant chemoradiation for localized adenocarcinoma of the pancreas Great logic, grim reality. Ann Surg Oncol. 8:2001;747-748
12. Monges G., Mathoulin-Portier M.P., Acres B., et al. Differential MUC 1 Expression in normal and neoplastic human pancreatic tissue. Am J Clin Pathol. 112:1999;635-640
13. Kaplan E.L., Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc. 53:1958;457-481
14. Mantel N. Evaluation of survival data and two new rank order statistics arising in its consideration. Cancer Chemother Rep. 50:1966;163-170
15. Kimura W., Han I., Furukawa Y., et al. Appleby operation for carcinoma of the body and tail of the pancreas. Hepatogastroenterology. 44:1997;387-393
16. Wanebo H.J., Glicksman A.S., Verzeridis M.P., et al. Preoperative chemotherapy, radiotherapy, and surgical resection of locally advanced pancreatic cancer. Arch Surg. 135:2000;81-87
17. Mehta V.K., Fisher G., Ford J.A., et al. Preoperative chemoradiation for marginally resectable adenocarcinoma of the pancreas. J Gastrointest Surg. 5:2001;27-35
18. Mertz H.R., Sechopoulos P., Delbeke D., et al. EUS, PET, and CT scanning for evaluation of pancreatic carcinoma. Gastrointest Endosc. 52:2000;367-371
19. Kim N.K., Kim N.J., Yun S.H., et al. Comparative study of transrectal ultrasonography, pelvic computerized tomography, and magnetic resonance imaging in preoperative staging of rectal cancer. Dis Col Rect. 42:1999;770-775
20. Beseth B.D., Bedford R., Isacoff W.H., et al. Endoscopic ultrasound does not accurately assess pathologic stage of esophageal cancer after neoadjuvant chemoradiotherapy. Am Surg. 66:2000;827-831
21. Willet C.G., Lewandrowski K., Warshaw A.L., et al. Resection margins in carcinoma of the head of the pancreas Implication for radiation therapy. Ann Surg. 217:1993;144-148
22. Yeo C.J., Cameron J.L., Lillemoe K.D., et al. Pancraticoduodenectomy for cancer of the head of the pancreas 201 patients. Ann Surg. 221:1995;721-733
23. Yeo C.J., Abrams R.A., Grochow L.B., et al. Pancreaticoduodenectomy for pancreatic adenocarcinoma Postoperative adjuvant chemoradiation improves survival - A prospective, single-institution experience. Ann Surg. 225:1997;621-636
24. Breslin T.M., Hess K.R., Harbison D.B., et al. Neoadjuvant chemoradiotherapy for adenocarcinoma of the pancreas Treatment variables and survival duration. Ann Surg Oncol. 8:2001;123-132
25. Sohn T.A., Yeo C.J., Cameron J.L., et al. Resected adenocarcinoma of the pancreas - 616 patients Results, outcomes, and prognostic indicators. J Gastrointest Surg. 4:2000;567-579
26. Fortner J.G., Klimstra D.S., Senie R.T., et al. Tumor size is the primary prognosticator for pancreatic cancer after regional pancreatectomy. Ann Surg. 223:1996;147-153
27. Conlon K.C., Klimstra D.S., Brennan M.F. Long-term survival after curative resection for pancreatic ductal adenocarcinoma Clinicopathologic analysis of 5-year survivors. Ann Surg. 223:1996;273-279
28. Biankin A.V., Morey A.L., Soon Lee C.S., et al. DPC4/Smad4 expression and outcome in pancreatic ductal adenocarcinoma. J Clin Oncol. 20:2002;4531-4542