Transplantation of iris pigment epithelium;Transplantation von irispigmentepithel

Ophthalmologe

Volumn 101, Issue 9, 2004, Pages 882-885

  Thumann, G ^a,b   Kirchhof, B ^a  

^a UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^b UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Age related macular degeneration; Iris pigment epithelium; Retinal pigment epithelium; Transdifferentiation; Transplantation

Indexed keywords

ARTICLE; CELL DIFFERENTIATION; CELL FUNCTION; CELL MEMBRANE; CELL STRUCTURE; CELL SUSPENSION; HUMAN; IMMUNOHISTOCHEMISTRY; IRIS; PHAGOCYTOSIS; PIGMENT CELL; RETINA MACULA AGE RELATED DEGENERATION; STEM CELL TRANSPLANTATION; SUBRETINAL NEOVASCULARIZATION; VISUAL ACUITY;

EID: 4544243723     PISSN: 0941293X     EISSN: 14330423     Source Type: Journal    
DOI: 10.1007/s00347-004-1084-3     Document Type: Article

References (30)

1. Abe T, Tomita H, Ohashi T et al. (1999) Characterization of iris pigment epithelial cell for auto cell transplantation. Cell Transplant 8:501-510
2. Abe T, Yoshida M, Tomita H et al. (2000) Auto iris pigment epithelial cell transplantation in patients with age-related macular degeneration: short-term results. Tohoku J Exp Med 191:7-20
3. Algvere PV, Berglin L, Gouras P, Sheng Y, Kopp ED (1997) Transplantation of RPE in age-related macular degeneration: observations in disciform lesions and dry RPE atrophy. Graefes Arch Clin Exp Ophthalmol 235:149-158
4. Binder S, Stolba U, Krebs I et al. (2002) Transplantation of autologous retinal pigment epithelium in eyes with foveal neovascularization resulting from age-related macular degeneration: a pilot study. Am J Ophthalmol 133:215-225
5. Crafoord S, Geng L, Seregard S, Algvere PV (2002) Photoreceptor survival in transplantation of autologous iris pigment epithelial cells to the subretinal space. Acta Ophthalmol Scand 80:387-394
6. Freddo TF (1984) Intercellular junctions of the iris epithelia in Macaca mulatta. Invest Ophthalmol Vis Sci 25:1094-1104
7. Hartmann U, Sistani F, Steinhorst UH (1999) Human and porcine anterior lens capsule as support for growing and grafting retinal pigment epithelium and iris pigment epithelium. Graefes Arch Clin Exp Ophthalmol 237:940-945
8. Holz FG, Bindewald A, Schutt F, Specht H (2003) Intraocular microablation of choroidal tissue by a 308 nm AIDA excimer laser for RPE-transplantation in patients with age-related macular degeneration. Biomed Tech 48:82-85
9. Hu DN, Ritch R, McCormick SA, Pelton-Henrion K (1992) Isolation and cultivation of human iris pigment epithelium. Invest Ophthalmol Vis Sci 33:2443-2453
10. Kano T, Abe T, Tomita H, Sakata T, Ishiguro S, Tamai M (2002) Protective effect against ischemia and light damage of iris pigment epithelial cells transfected with the BDNF gene. Invest Ophthalmol Vis Sci 43:3744-3753
11. Kivela T, Jaaskelainen J, Vaheri A, Carpen O (2000) Ezrin, a membrane-organizing protein, as a polarization marker of the retinal pigment epithelium in vertebrates. Cell Tissue Res 301:217-223
12. Kociok N, Heppekausen H, Schraermeyer U, Esser P, Thumann G, Grisanti S, Heimann K (1998) The mRNA expression of cytokines and their receptors in cultured iris pigment epithelial cells: a comparison with retinal pigment epithelial cells. Exp Eye Res 67:237-250
13. Lappas A, Weinberger AW, Foerster AM, Kube T, Rezai KA, Kirchhof B (2000) Iris pigment epithelial cell translocation in exudative age-related macular degeneration. A pilot study in patients. Graefes Arch Clin Exp Ophthalmol 238:631-641
14. Rezai KA, Lappas A, Farrokh-siar L, Kohen L, Wiedemann P, Heimann K (1997) Iris pigment epithelial cells of long evans rats demonstrate phagocytic activity. Exp Eye Res 65:23-29
15. Rezai KA, Lappas A, Kohen L, Wiedemann P, Heimann K (1997) Comparison of tight junction permeability for albumin in iris pigment epithelium and retinal pigment epithelium in vitro. Graefes Arch Clin Exp Ophthalmol 235:48-55
16. Sakuragi M, Tomita H, Abe T, Jamai M (2001) Changes of phagocytic capacity in basic fibroblast growth factor-transfected iris pigment epithelial cells in rats. Curr Eye Res 23:185-191
17. Scheider A, Gundisch O, Kampik A (1999) Surgical extraction of subfoveal choroidal new vessels and submacular haemorrhage in age-related macular degeneration: results of a prospective study. Graefes Arch Clin Exp Ophthalmol 237:10-15
18. Semkova I, Kreppel F, Welsandt G et al. (2002) Autologous transplantation of genetically modified iris pigment epithelial cells: a promising concept for the treatment of age-related macular degeneration and other disorders of the eye. Proc Natl Acad Sci U S A 99:13090-13095
19. Steinhorst UH, Amdreae A, Sistani F, Waldmann KH, Kastern T (2001) Autologous subretinal transplantation of cultivated porcine iris pigment epithelial cells (IPE). Klin Monatsbl Augenheilkd 218:192-196
20. Sugano E, Tomita H, Abe T, Yamashita A, Tamai M (2003) Comparative study of cathepsins D and S in rat IPE and RPE cells. Exp Eye Res 77:203-209
21. Thumann G, Schraermeyer U, Bartz-Schmidt KU, Heimann K (1997) Descemet's membrane as membranous support in RPE/IPE transplantation. Curr Eye Res 16:1236-1238
22. Thumann G, Bartz-Schmidt KU, Heimann K, Schraermeyer U (1998) Phagocytosis of rod outer segments by human iris pigment epithelial cells in vitro. Graefes Arch Clin Exp Ophthalmol 236:753-757
23. Thumann G, Bartz-Schmidt KU, El Bakri H et al. (1999) Transplantation of autologous iris pigment epithelium to the subretinal space in rabbits. Transplantation 68:195-201
24. Thumann G, Kociok N, Bartz-Schmidt KU, Esser P, Schraermeyer U, Heimann K (1999) Detection of mRNA for proteins involved in retinol metabolism in iris pigment epithelium. Graefes Arch Clin Exp Ophthalmol 237:1046-1051
25. Thumann G, Kociok N, Bartz-Schmidt KU, Esser P, Schraermeyer U, Heimann K (1999) Detection of mRIMA for proteins involved in retinol metabolism in iris pigment epithelium. Graefes Arch Clin Exp Ophthalmol 237:1046-1051
26. Thumann G, Aisenbrey S, Schraermeyer U, Lafaut B, Esser P, Walter P, Bartz-Schmidt KU (2000) Transplantation of autologous iris pigment epithelium after removal of choroidal neovascular membranes. Arch Ophthalmol 118:1350-1355
27. Von Recum HA, Okano T, Kim SW, Bernstein PS (1999) Maintenance of retinoid metabolism in human retinal pigment epithelium cell culture. Exp Eye Res 69:97-107
28. Weimer EG, Cinatl J, Ohrloff C, Bratzke H, Gumbel HO (2000) In vitro culture of iris cells. Klin Monatsbl Augenheilkd 217:356-362
29. Yasuda K, Shimura M, Nakazawa T, Sato H, Tomita H, Sugano E, Tamai M (2003) Expression and functional properties of unique inward rectifier K+ channel Kir7.1 in the porcine iris and retinal pigment epithelium. Curr Eye Res 27:279-287
30. Zhao S, Rizzolo U, Barnstable CJ (1997) Differentiation and transdifferentiation of the retinal pigment epithelium. Int Rev Cytol 171:225-266