Tissue oxygenation in sepsis; new insights from in vivo EPR

NMR in Biomedicine

Volumn 17, Issue 5, 2004, Pages 319-326

  James, Philip E ^a   Thomas, Matthew P ^a   Jackson, Simon K ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

EPR; Nitric oxide; Sepsis; Tissue oxygenation

Indexed keywords

BIOLOGICAL ORGANS; MATHEMATICAL MODELS; NITROGEN OXIDES; OXYGEN; TISSUE;

ANIMAL MODELS; ORGAN DYSFUNCTION; SEPSIS; TISSUE OXYGENATION;

PARAMAGNETIC RESONANCE;

NITRIC OXIDE; OXYGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DISEASE MODEL; ELECTRON SPIN RESONANCE; IN VIVO STUDY; MOUSE; NONHUMAN; OXYGEN BLOOD LEVEL; OXYGEN CONSUMPTION; OXYGEN TENSION; OXYGEN TRANSPORT; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SENSITIVITY ANALYSIS; SEPSIS; SPIN TRAPPING; TISSUE DISTRIBUTION; TISSUE OXYGENATION;

ALGORITHMS; ANIMALS; BIOLOGICAL MARKERS; BRAIN; CONNECTIVE TISSUE; DISEASE MODELS, ANIMAL; ELECTRON SPIN RESONANCE SPECTROSCOPY; HUMANS; NITRIC OXIDE; OXYGEN; SEPSIS;

ANIMALIA;

EID: 4544229562     PISSN: 09523480     EISSN: None     Source Type: Journal    
DOI: 10.1002/nbm.910     Document Type: Article

References (35)

1. Angus DC, Linde-Zwirble WT, Lidicker J, Clermont G, Carcillo J, Pinsky MR. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit. Care Med. 2001; 29: 1303-1310.
2. Glauser MP, Zanetti G, Baumgartner JD, Cohen J. Septic shock: pathogenesis. Lancet 1991; 338: 732-736.
3. Thiemermann C. Nitric oxide and septic shock. Gen. Pharmac. 1997; 29: 159-166.
4. Vos TA, Gouw AS, Klok PA, Havinga R, van Goor H, Huitema S, Roelofsen H, Kuipers F, Jansen PL, Moshage H. Differential effects of nitric oxide synthase inhibitors on endotoxin-induced liver damage in rats. Gastroenterology 1997; 113: 1323-1333.
5. Beckman JS. The physiological and pathological chemistry of nitric oxide. Nitric Oxide: Principles and Actions, Lancaster J (ed.). Academic Press: London, 1996; 1-82.
6. Billiar TR, Curran RD, Harbrecht BG, Stuehr DJ, Demetris AJ, Simmons RL. Modulation of nitrogen oxide synthesis in vivo: NG-monomethyl-L-arginine inhibits endotoxin-induced nitrite/nitrate biosynthesis while promoting hepatic damage. J. Leukocyte Biol. 1990; 48: 565-569.
7. Di Silvo M, Nussler AK, Geller DA, Billiar TR. A role for nitric oxide in liver inflammation and infection. In Nitric Oxide: Principles and Actions, Lancaster J (ed.). Academic Press: London, 1996; 219-236.
8. James PE, Madhani M, Roebuck W, Jackson SK, Swartz HM. Endotoxin-induced liver hypoxia: defective oxygen delivery versus oxygen consumption. Nitric Oxide 2002; 6: 18-28.
9. Wilson DF, Erecinska M, Sandler S, Nelson D. The oxygen dependence of cytochrome c oxidase in oxidative phosphorylation. In Oxidases and Related Redox Systems, King TE, Mason HS, Morrison W (eds). Pergamon Press: New York, 1982; 1119.
10. Vanderkooi JM, Erecinska M, Silver IA. Oxygen in mammalian tissue: methods of measurements and affinities of various reactions. Am. J. Physiol. 1991; 260: C1131-C1150.
11. 2 during acute hypoxia in rat brain using a time-resolved luminescence-based oxygen sensor. Adv. Exp. Med. Biol. 1999; 471: 43-48.
12. Collingridge DR, Young WK, Vojnovic B, Wardman P, Lynch EM, Hill SA, Chaplin DJ. Measurement of tumor oxygenation: a comparison between polarographic needle electrodes and a time-resolved luminescence based optical, sensor. Radiat. Res. 1997; 147: 329-334.
13. Mancini DM, Wilson JR, Bolinger L, Li H, Kendrick K, Chance B, Leigh JS. In vivo magnetic resonance spectroscopy measurement of deoxymyoglobin during exercise in patients with heart failure. Demonstration of abnormal muscle metabolism despite adequate oxygenation. Circulation 1994: 90: 500-508.
14. Ogawa S, Lee TM, Kay AR, Tank DW. Brain magnetic resonance imaging with contrast dependent on blood oxygenation. Proc. Natl Acad. Sci. USA 1990; 87: 9868-9872.
15. Dunn JF, Swartz HM. Blood oxygenation: heterogeneity of hypoxic tissues monitored using BOLD MR imaging. Adv. Exp. Biol. Med 1998; 428: 645-650.
16. Mason RP, Rodbumrung W, Antich PP. Hexafluorobenzene: a sensitive 19F NMR indicator of tumor oxygenation. NMR Biomed. 1996; 9: 125-134.
17. Hunjan S, Mason RP, Constantinescu A, Peschke P, Hahn EW, Antich PP. Regional tumor oximetry: 19F NMR spectroscopy of hexafluorobenzene. Int. J. Radiat Oncol. Biol. Phys. 1998; 41: 161-171.
18. Sotak CH, Hees PS, Huang HN, Hung M, Krespan CG, Raynolds S. A new perfluorocarbon for use in fluorine-19 magnetic resonance imaging and spectroscopy. Magn. Reson. Med. 1993; 29: 188-195.
19. 19F-MR relaxometry. Int. J. Radiat Oncol. Biol. Phys. 1999; 44: 649-658.
20. Swartz HM. The measurement of oxygen in vivo using EPR techniques. In Biological Magnetic Resonance Vol. 20: in vivo EPR (ESR): Theory and Applications, Berliner LJ (ed.). Plenum Press: New York, 2002.
21. Swartz HM, Clarkson RB. The measurement of oxygen in vivo using EPR techniques. Phys. Med. Biol. 1998; 43: 1957-1975.
22. 2 and NO in endotoxin shock. Toxicol. Lett. 2001; 120: 253-257.
23. Ardenkjaer-Larsen JH, Laursen I, Leunbach I, Ehnholm G, Wistrand LG, Petersson JS, Golman K. EPR and DNP properties of certain novel single electron contrast agents intended for oximetric imaging. J. Magn. Reson. 1998; 133: 1-12.
24. Liu KJ, Gast P, Moussavi M, Norby SW, Vahidi N, Walczak T, Wu M, Swartz HM. Lithium phthalocyanine: a probe for electron paramagnetic resonance oximetry in viable biological systems. Proc. Natl Acad. Sci. USA 1993; 90: 5438-5442.
25. James PE, Grinberg OY, Goda F, Panz T, O'Hara JA, Swartz HM. Gloxy: an oxygen-sensitive coal for accurate measurement of low oxygen tensions in biological systems. Magn. Reson. Med. 1997; 38: 48-58.
26. Miyake M, O'Hara JA, James PE, Panz T, Swartz HM. Histological examination of the biological interactions of the oxygen sensitive paramagnetic material gloxy with various tissues of mice. Proceedings of ESR (EPR) Imaging and In vivo ESR Spectroscopy, Kamada H, Ohya H (eds). Yamagata; 252-254.
27. Goda F, Liu KJ, Walczak T, O'Hara JA, Jiang J, Swartz HM. In vivo oximetry using EPR and India ink. Magn. Reson. Med 1995; 33: 237-245.
28. Teale DM, Atkinson AM. Inhibition of nitric oxide synthesis improves survival in a murine peritonitis model of sepsis that is not cured by antibiotics alone. J. Antimicrob. Chemother. 1992; 30: 839-842.
29. Ritter C, Andrades M, Frota Junior ML, Bonatto F, Pinho RA, Polydoro M, Klamt F, Pinheiro CT, Menna-Barreto SS, Moreira JC, Dal-Pizzol F. Oxidative parameters and mortality in sepsis induced by cecal ligation and perforation. Intensive Care Med. 2003; 29: 1782-1789.
30. Madhani M, Klei L, Barchowsky A, Jackson SK, Swartz HM, James PE. Anti-bacterial peptide PR-39 affects local nitric oxide and preserves tissue oxygenation in the liver during septic shock. Biochim. Biophys. Acta 2002; 1588: 232-240.
31. James PE, Bacic G, Grinberg O, Goda F, Jackson SK, Dunn J, Swartz HM. Renal oxygenation during endotoxemia as monitored by in vivo EPR oximetry and MR imaging. Free Rad. Biol. Med. 1995; 21: 25-34.
32. Jackson SK, Thomas MJ, Smith S, Madhani M, Rogers SC, James PE. In vivo EPR spectroscopy: biomedical and potential diagnostic applications. J. Chem. Soc. Faraday Discuss. 2004; 126: 103-117 [discussion 169-183.]
33. 2 in a mouse model measured by EPR spectroscopy. Adv. Exp. Med. Biol. 2002; 510: 205-211.
34. 2 by EPR. Meth. Enzymol. 2002; 359: 52-66.
35. Elas M, Williams BB, Parasca A, Mailer C, Pelizzari CA, Lewis MA, River JN, Karczmar GS, Barth ED, Halpern HJ. Quantitative tumor oxymetric images from 4D electron paramagnetic resonance imaging (EPRI): methodology and comparison with blood oxygen level-dependent (BOLD) MRI. Magn. Reson. Med. 2003; 49: 682-691.