Amidomethylation of amodiaquine: Antimalarial N-Mannich base derivatives

Tetrahedron Letters

Volumn 45, Issue 41, 2004, Pages 7663-7666

  Lopes, Francisca ^a   Capela, Rita ^a   Gonçaves, José O ^a   Horton, Peter N ^b   Hursthouse, Michael B ^b   Iley, Jim ^c   Casimiro, Catarina M ^d   Bom, Joana ^d   Moreira, Rui ^a  

^a UNIVERSITY OF LISBON   (Portugal)

^b UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^c OPEN UNIVERSITY   (United Kingdom)

^d IHMT   (Portugal)

Author keywords

Amidomethylation; Amodiaquine; Antimalarial

Indexed keywords

AMIDE; AMODIAQUINE; ANTIMALARIAL AGENT; AROMATIC AMINE; CHLOROQUINE; HIPPURIC ACID DERIVATIVE; MANNICH BASE;

ANTIMALARIAL ACTIVITY; ARTICLE; CHEMICAL MODIFICATION; CHEMICAL REACTION KINETICS; CONTROLLED STUDY; DRUG STABILITY; DRUG SYNTHESIS; ENZYME MECHANISM; HUMAN; METHYLATION; NONHUMAN; PLASMODIUM FALCIPARUM; REACTION ANALYSIS;

PLASMODIUM FALCIPARUM;

EID: 4544220004     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2004.08.093     Document Type: Article

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