Cholesterol binding is a prerequisite for the activity of the steroidogenic acute regulatory protein (StAR)

Biochemical Journal

Volumn 412, Issue 3, 2008, Pages 553-562

  Roostaee, Alireza ^a   Barbar, Élie ^a   LeHoux, Jean Guy ^a   Lavigne, Pierre ^a  

^a UNIVERSITY OF SHERBROOKE   (Canada)

Author keywords

Cholesterol; Circular dichroism; Mitochondria; Steroidogenesis; Steroidogenic acute regulatory protein (StAR); Thermodynamics

Indexed keywords

AMINES; AMINO ACIDS; BINDING ENERGY; BINDING SITES; CELL MEMBRANES; ENZYME ACTIVITY; HEALTH; HYDROPHOBICITY; MECHANICS; MELTING POINT; MICROFLUIDICS; MOLECULES; ORGANIC ACIDS; PORT TERMINALS; SYSTEM STABILITY; THERMODYNAMIC STABILITY; THERMODYNAMICS; VOLUMETRIC ANALYSIS;

AMINO ACID RESIDUES; BINDING AFFINITIES; BINDING CAPACITIES; BIOLOGICAL ACTIVITIES; C TERMINAL HELIX; CHOLESTEROL BINDING; CHOLESTEROL TRANSPORT; HELICAL CONTENT; HYDROPHOBIC CAVITIES; IN VITRO ACTIVITY; MELTING TEMPERATURE (TM); MITOCHONDRIAL MEMBRANES; MOLECULAR MODELLING; N TERMINALS; SIDE-CHAINS; STEROIDOGENESIS; STEROIDOGENIC ACUTE REGULATORY (STAR) PROTEINS; TERTIARY STRUCTURES;

CHOLESTEROL;

AMINO ACID; CHOLESTEROL; STEROIDOGENIC ACUTE REGULATORY PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DISSOCIATION CONSTANT; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN FOLDING; PROTEIN FUNCTION; STEROIDOGENESIS;

BINDING SITES; CHOLESTEROL; CLONING, MOLECULAR; HUMANS; HYDROGEN-ION CONCENTRATION; MODELS, MOLECULAR; PHOSPHOPROTEINS; PROTEIN CONFORMATION; PROTEIN FOLDING; TEMPERATURE; THERMODYNAMICS;

EID: 45349096923     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20071264     Document Type: Article

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