Epidemiology of osteoporosis

Clinical Cases in Mineral and Bone Metabolism

Volumn 5, Issue 1, 2008, Pages 11-13

  Masi, Laura ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Atherosclerosis; Fetuin A calcium phosphate mineral phase complex; Matrix Gla proteins (Mgp); OPG RANK RANK L system; Osteoporosis; Vitamin D

Indexed keywords

CALCITRIOL; CALCIUM BINDING PROTEIN; CALCIUM PHOSPHATE; FETUIN A; MATRIX GLA PROTEIN; OSTEOCLAST DIFFERENTIATION FACTOR; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; TUMOR NECROSIS FACTOR RECEPTOR; VITAMIN D;

ADVERSE OUTCOME; ATHEROSCLEROSIS; BLOOD VESSEL CALCIFICATION; BONE GROWTH; BONE MASS; BONE METABOLISM; BONE REMODELING; BONE STRENGTH; FRAGILITY FRACTURE; HIP FRACTURE; HOMEOSTASIS; HUMAN; NONHUMAN; OSTEOCLAST; OSTEOPOROSIS; PREVALENCE; RISK FACTOR; SHORT SURVEY; VERTEBRA FRACTURE; WRIST FRACTURE;

EID: 45349092464     PISSN: 17248914     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Short Survey

References (40)

1. Cummings SR, Melton LJ. Epidemiology and outcomes of osteoporotic fractures. The Lancet. 2002;359:1761-1767.
2. NIH/ORBD, www.osteo.org, 2000.
3. Melton LJ III. Who has osteoporosis? A conflict between clinical and public health perspectives. J Bone Miner Res. 2000;15:2309-2314.
4. Keene GS, Parker MJ, Pryor GA. Mortality and morbidity after hip fractures. BMJ. 1993;307:1248-1250.
5. Jhonell O, Gullberg B, Allander E et al. The apparent incidence of hip fracture in Europe: a study of national register sources. Osteoporosis Int. 1992;2:298-302.
6. Nevett MC, Ross PT, Palermo L, Musliner T, Genant HK, Thompson DE. Association of prevalent vertebral fractures, bone density, and alendronate treatment with incident vertebral fractures: effect of number and spinal location of fractures. The Fracture Intervention Trial Research Group. Bone. 1999;25:613-619.
7. Kanis JA, Brogstrom F, De Laet C, Johansson H, Johnell O, Jonsson B, Oden A, Zethraeus N, Pfleger B, Khaltaev N. Assessment of fracture risk. Osteoporosis Int. 2005;16:581-589.
8. Trombetti A, Herrmann F, Hoffmeyer P, Schurch MA, Bonjour JP, Rizzoli R. Survival and potential years of life lost after hip fracture in men and age-matched women. Osteoporosis Int. 2002;13:731-737.
9. Compston JE. Hormone replacement therapy for osteoporosis: clinical and pathophysiological aspects. Repro Med Rev. 1994;3: 209-224.
10. Manolagas SC. Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis. Endocrine Rev. 2000; 21:1132-1136.
11. Hughes DE, Dai A, Tiffee JC, Li HH, Mundy GR, Boyce BF. Estrogen promotes apoptosis of murine osteoclasts mediated by TGF-β. Nat Med. 1996;2:1132-1136.
12. Riggs BL, Khosla S, Melton LJ. Sex Steroids and the Construction and Conservation of the Adult Skeleton. Endocrine Rev. 2002;23: 279-302.
13. Bellido T, Jilka R, Boyce B, Girasole G, Broxmeyer H, Dalrymple S, Murray R, Manolagas S. Regulation of interleukin-6, osteoclastogenesis, and bone mass by androgens. J Clin Invest. 1995;95: 2886-2895.
14. Falahati-Nini A, Riggs BL, Atkinson EJ, O'Fallon WM, Eastell R, Khosla S. Relative contributions of testosterone and estrogen in regulating bone resorption and formation in normal elderly men. J Clin Invest. 2000;106:1553-1560.
15. Chen JR, Kousteni S, Bellido T, Han L, DiGregorio GB, Jilka RL, Manolagas SC. Gender-independent induction of murine osteoclast apoptosis in vitro by either estrogens or non-aromatizable androgens. J Bone Miner Res. 2001;16(Suppl 1):S159.
16. Khosla S, Melton III U, Atkinson EJ, O'Fallon WM, Klee GG, Riggs BL. Relationship of serum sex steroid levels and bone turnover markers with bone mineral density in men and women: a key role for bioavailable estrogen. J Clin Endocrinol Metab. 1998;83:2266-2274.
17. Rajaram S, Baylink DJ, Mohan S. Insulin-like growth factor-binding proteins in serum and other biological fluids: regulation and functions. Endocr Rev. 1997;18:801-831.
18. von Schoultz B, Carlstrom K. On the regulation of sex-hormone-binding globulin-a challenge of an old dogma and outlines of an alternative mechanism. J Steroid Biochem. 1989;32:327-334.
19. Hauge EM, Qvesel D, Eriksen EF, Mosekilde L, Melsen F. Cancellous bone remodeling occurs in specialized compartments lined by cells expressing osteoblastic markers. J Bone Miner Res. 2001; 16:1575-1582.
20. Eriksen EF, Eghbali-Fatourechi GZ, Khosla S. Remodeling and vascular spaces in bone J Bone Miner Res. 2007;22:1-6.
21. Kado DM, Browner WS, Blackwell T, Gore R, Cummings SR. Rate of bone loss is associated with mortality in older women: a prospective study. J Bone Miner Res. 2000;15:1974-1980.
22. Hulley SB, Bittner V, Furberg C, Grady D, Herrington D, Vittinghoff E, Wenger N. Hormone treatment-misconceptions and agreements. Eur Heart J. 2002;23(1):89-91.
23. Tankó LB, Christiansen C, Cox DA, Geiger MJ, McNabb MA, Cummings SR. Relationship between osteoporosis and cardiovascular disease in postmenopausal women. J Bone Miner Res. 2005;20: 1912-20.
24. Jono S, Nishizawa Y, Shioi A, Morii H. 1,25-Dihydroxyvitamin D3 increases in vitro vascular calcification by modulating secretion of endogenous parathyroid hormone-related peptide. Circulation. 1998;98:1302-1306.
25. Resnick LM, Mulller FB, Laragh JH. Calcium-regulating hormones in essential hypertension. Relation to plasma renin activity and sodium metabolism. Ann Intern Med. 1986;105:649-654.
26. Li YC. Vitamin D regulation of the renin-angiotensin system. J Cell Biochem. 2003;88:327-331.
27. Pittas AG, Lau J, Hu FB, Dawson-Hughes B. The role of vitamin D and calcium in type 2 diabetes. A systematic review and metaanalysis. J Clin Endocrinol Metab. 2007;92:2017-2019.
28. Hofbauer LC, Heufelder AE. Role of the receptor activator of nuclear factor-kappaB ligand and osteoprotegerin in bone cell biology. J Mol Med. 2001;79:243-253.
29. Sandberg WJ, Yndestad A, Oie C, Smith C, Ueland T, Ovchinnikova O, Robertson AKL, Muller F, Semb AG, Scholz H, Andersossen K, Gullestad L, Damas JK, Froland SS, Hansson GK, Halvorsen B, Aurkust P. Enhanced T-cell expression of RANK ligand in acute coronary syndrome: possible role in plaque destabilization. Arterioscler Thromb Vasc Biol. 2006;857-863.
30. Bucay N, Sarosi I, Dunstan CR, Morony S, Tarpley J, Capparelli C, Scully S, Tan HL, Xu W, Lacey DL, Boyle WJ, Simonet WS. Osteoprotegerin deficient mice develop early onset osteoporosis and arterial calcification. Genes Develop. 1998;12:1260-1268.
31. Min H, Morony S, Sarosi I, Dunstan CR, Capparelli C, Scully S, Van G, Kaufman S, Kostenuik PJ, Lacey DL, Boyle WJ, Simonet WS. Osteoprotegerin reverses osteoporosis by inhibiting endostal osteoclasts and prevent vascular calcification by blocking a process resembling osteoclastogenesis. J Exp Med. 2000;192: 463-474.
32. Hamerman D. Osteoporosis and atherosclerosis: biological linkages and the emergence of dual-purpose therapies Q J Med. 2005;98: 467-484.
33. Price PA, June HH, Buckley JR, Williamson MK. Osteoprotegerin inhibit artery calcification induced by warfarin and by vitamin D. Arterioscler Thromb Vasc Biol. 2001;21:1610-1616.
34. Li J, Sarosi I, Yan XQ, Morony S, Capparelli C, Tan HL, McCabe S, Elliott R, Scully S, Van G, Kaufman S, Juan SC, Sun Y, Tarpley J, Martin L, Christensen K, McCabe J, Kostenuik P, Hsu H, Fletcher F, Dunstan CR, Lacey DL, Boyle WJ. RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism. Proc Natl Acad Sci U S A. 2000;97:1566-1571.
35. Schoppet M, Preissner KL, Hofbauer C. RANK Ligand and osteoprotegerin. Paracrine Regulators of bone metabolism and vascular function. Arterioscler Thromb Vasc Biol. 2002;22:549-553.
36. Kim YM, Lee YM et al. TNF-related activation-induced cytokine (TRANCE) induces angiogenesis through the activation of Src and phospholipase C (PLC) in human endothelial cells. J Biol Chem. 2002;277:6799-6805.
37. Fukumara D, Jain RK. Novel function of RANKL: eNOS activator. Blood. 2007;109:1339-1340.
38. Sweatt A, Sane DC, Hutson SM. Matrix Gla protein (Mpg) and bone morphogenetic protein-2 in aortic calcified lesions of aging rats. J Thromb Haemost. 2003;1:178-185.
39. El-Maadawy S, Kaartinen MT, Schinke T, Murshed M, Karsenty G, McKee MD. Cartilage formation and calcification in arteries of mice lacking matrix Gla protein. Connect Tissue Res. 2003;1:272-278.
40. Jahnen-Dechent W, Schinke T, Trindl A, Müller-Esterl W, Sablitzky F, Kaiser S, Blessing M. Cloning and targeted deletion of the mouse fetuin gene. J Biol Chem. 1997;272:31496-31503.