Synergistic effect of ethanol and mitomycin C on corneal stroma

Journal of Refractive Surgery

Volumn 24, Issue 6, 2008, Pages 626-632

  Netto, Marcelo V ^a   Barreto Jr , Jackson ^a   Santo, Ruth ^a   Bechara, Samir ^a   Kara Jose, Newton ^a   Wilson, Steven E ^b  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4',6 DIAMIDINO 2 PHENYLINDOLE; ALCOHOL; ALPHA SMOOTH MUSCLE ACTIN; MITOMYCIN C;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DENSITY; CONTROLLED STUDY; CORNEA CELL; CORNEA EPITHELIUM; CORNEA STROMA; CYTOTOXICITY; DEBRIDEMENT; DRUG ALCOHOL INTERACTION; DRUG POTENTIATION; EXCIMER LASER; IMMUNOHISTOCHEMISTRY; LASER SURGERY; MYOPIA; NICK END LABELING; NONHUMAN; PHOTOREFRACTIVE KERATECTOMY; PRIORITY JOURNAL; RABBIT;

EID: 45249097529     PISSN: 1081597X     EISSN: None     Source Type: Journal    
DOI: 10.3928/1081597x-20080601-13     Document Type: Article

References (35)

1. Ambrosio R Jr, Wilson S. LASIK vs LASEK vs PRK: advantages and indications. Semin Ophthalmol. 2003;18:2-10.
2. Pop M, Payette Y. Photorefractive keratectomy versus laser in situ keratomileusis: a control-matched study. Ophthalmology. 2000;107:251-257.
3. Walker MB, Wilson SE. Recovery of uncorrected visual acuity after laser in situ keratomileusis or photorefractive keratectomy for low myopia. Cornea. 2001;20:153-155.
4. Netto MV, Wilson SE. Indications for excimer laser surface ablation. J Refract Surg. 2005;21:734-741.
5. Rajan MS, Jaycock P, O'Brart D, Nystrom HH, Marshall J. A long-term study of photorefractive keratectomy; 12-year followup. Ophthalmology. 2004;111:1813-1824.
6. Binder PS. Ectasia after laser in situ keratomileusis. J Cataract Refract Surg. 2003;29:2419-2429.
7. Dupps WJ Jr, Wilson SE. Biomechanics and wound healing in the cornea. Exp Eye Res. 2006;83:709-720.
8. Klein SR, Epstein RJ, Randleman JB, Stulting RD. Corneal ectasia after laser in situ keratomileusis in patients without apparent preoperative risk factors. Cornea. 2006;25:388-403.
9. Netto MV, Mohan RR, Ambrosio R Jr, Hutcheon AE, Zieske JD, Wilson SE. Wound healing in the cornea: a review of refractive surgery complications and new prospects for therapy. Cornea. 2005;24:509-522.
10. Talamo JH, Gollamudi S, Green WR, De La Cruz Z, Filatov V, Stark WJ. Modulation of corneal wound healing after excimer laser keratomileusis using topical mitomycin C and steroids. Arch Ophthalmol. 1991;109:1141-1146.
11. Lai YH, Wang HZ, Lin CP, Chang SJ. Mitomycin C alters corneal stromal wound healing and corneal haze in rabbits after argon-fluoride excimer laser photorefractive keratectomy. J Ocul Pharmacol Ther. 2004;20:129-138.
12. Xu H, Liu S, Xia X, Huang P, Wang P, Wu X. Mitomycin C reduces haze formation in rabbits after excimer laser photorefractive keratectomy. J Refract Surg. 2001;17:342-349.
13. Jain S, McCally RL, Connolly PJ, Azar DT. Mitomycin C reduces corneal light scattering after excimer keratectomy. Cornea. 2001;20:45-49.
14. Majmudar PA, Forstot SL, Dennis RF, Nirankari VS, Damiano RE, Brenart R, Epstein RJ. Topical mitomycin-C for subepithelial fibrosis after refractive corneal surgery. Ophthalmology. 2000;107:89-94.
15. Carones F, Vigo L, Scandola E, Vacchini L. Evaluation of the prophylactic use of mitomycin-C to inhibit haze formation after photorefractive keratectomy. J Cataract Refract Surg. 2002;28:2088-2095.
16. Gambato C, Ghirlando A, Moretto E, Busato F, Midena E. Mitomycin C modulation of corneal wound healing after photorefractive keratectomy in highly myopic eyes. Ophthalmology. 2005;112:208-218.
17. Solomon R, Donnenfeld ED, Perry HD. Photorefractive keratectomy with mitomycin C for the management of a LASIK flap complication following a penetrating keratoplasty. Cornea. 2004;23:403-405.
18. Chalita MR, Roth AS, Krueger RR. Wavefront-guided surface ablation with prophylactic use of mitomycin C after a buttonhole laser in situ keratomileusis flap. J Refract Surg. 2004;20:176-181.
19. Muller LT, Candal EM, Epstein RJ, Dennis RF, Majmudar PA. Transepithelial phototherapeutic keratectomy/photorefractive keratectomy with adjunctive mitomycin-C for complicated LASIK flaps. J Cataract Refract Surg. 2005;31:291-296.
20. Poster RR. Permanent corneal edema resulting from the treatment of PTK corneal haze with mitomycin: a case report. Cornea. 2004;23:744-747.
21. Morales AJ, Zadok D, Mora-Retana R, Martinez-Gama E, Robledo NE, Chayet AS. Intraoperative mitomycin and corneal endothelium after photorefractive keratectomy. Am J Ophthalmol. 2006;142:400-404.
22. Torres RM, Merayo-Lloves J, Daya SM, Blanco-Mezquita JT, Espinosa M, Nozal MJ, Bernal JL, Bernal J. Presence of mitomycin-C in the anterior chamber after photorefractive keratectomy. J Cataract Refract Surg. 2006;32:67-71.
23. Wu KY, Hong SJ, Huang HT, Lin CP, Chen CW. Toxic effects of mitomycin-C on cultured corneal keratocytes and endothelial cells. J Ocul Pharmacol Ther. 1999;15:401-411.
24. Kim TI, Tchah H, Lee SA, Sung K, Cho BJ, Kook MS. Apoptosis in keratocytes caused by mitomycin C. Invest Ophthalmol Vis Sci. 2003;44:1912-1917.
25. Netto MV, Mohan RR, Sinha S, Sharma A, Gupta PC, Wilson SE. Effect of prophylactic and therapeutic mitomycin C on corneal apoptosis, cellular proliferation, haze, and long-term keratocyte density in rabbits. J Refract Surg. 2006;22:562-574.
26. Kim TI, Pak JH, Lee SY, Tchah H. Mitomycin C-induced reduction of keratocytes and fibroblasts after photorefractive keratectomy. Invest Ophthalmol Vis Sci. 2004;45:2978-2984.
27. Matsunaga H, Katano M, Saita T, Yamamoto H, Mori M. Potentiation of cytotoxicity of mitomycin C by a polyacetylenic ethanol, panaxytriol. Cancer Chemother Pharmacol. 1994;33:291-297.
28. Kim TI, Tchah H, Cho EH, Kook MS. Evaluation for safety of cultured corneal fibroblasts with cotreatment of ethanol and mitomycin C. Invest Ophthalmol Vis Sci. 2004;45:86-92.
29. Jampel HD. Effect of brief exposure to mitomycin C on viability and proliferation of cultured human Tenon's capsule fibroblasts. Ophthalmology. 1992;99:1471-1476.
30. Watanabe J, Sawaguchi S, Fukuchi T, Abe H, Zhou L. Effects of mitomycin C on the expression of proliferating cell nuclear antigen after filtering surgery in rabbits. Graefes Arch Clin Exp Ophthalmol. 1997;235:234-240.
31. Blake CR, Cervantes-Castañeda RA, Macias-Rodríguez Y, Anzoulatous G, Anderson R, Chayet AS. Comparison of post-operative pain in patients following photorefractive keratectomy versus advanced surface ablation. J Cataract Refract Surg. 2005;31:1314-1319.
32. Carones F, Fiore T, Brancato R. Mechanical vs. alcohol epithelial removal during photorefractive keratectomy. J Refract Surg. 1999;15:556-562.
33. Lee HK, Lee KS, Kim JK, Kim HC, Seo KR, Kim EK. Epithelial healing and clinical outcomes in excimer laser photorefractive surgery following three epithelial removal techniques: mechanical, alcohol, and excimer laser. Am J Ophthalmol. 2005;139:56-63.
34. Chen CC, Chang JH, Lee JB, Javier J, Azar DT. Human corneal epithelial cell viability and morphology after dilute alcohol exposure. Invest Ophthalmol Vis Sci. 2002;43:2593-2602.
35. Mohan RR, Hutcheon AE, Choi R, Hong J, Lee J, Mohan RR, Ambrosio R Jr, Zieske JD, Wilson SE. Apoptosis, necrosis, proliferation, and myofibroblast generation in the stroma following LASIK and PRK. Exp Eye Res. 2003;76:193-201.