Anti-cancer drug diffusion within living rat brain tissue: An experimental study using [3H](6)-5-fluorouracil-loaded PLGA microspheres

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 53, Issue 3, 2002, Pages 293-299

  Roullin, Valérie Gaëlle ^a   Deverre, Jean Robert ^b   Lemaire, Laurent ^a   Hindré, François ^a   Venier Julienne, Marie Claire ^a   Vienet, Raymond ^b   Benoit, Jean Pierre ^a  

^a INSERM   (France)

^b Institut National de la Recherche Agronomique   (France)

Author keywords

5 Fluorouracil; C6 glioma; Diffusion; Drug delivery; Magnetite; Microsphere; Tissue combustion

Indexed keywords

ANTINEOPLASTIC AGENT; FLUOROURACIL; MAGNETITE; MICROSPHERE; POLYGLACTIN; TRITIUM;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; FEMALE; GLIOMA; IMPLANTATION; ISOTOPE LABELING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; RAT;

ANIMALS; ANTINEOPLASTIC AGENTS; BIOCOMPATIBLE MATERIALS; BRAIN; BRAIN NEOPLASMS; CONTRAST MEDIA; DIFFUSION; DRUG CARRIERS; FEMALE; FERROSOFERRIC OXIDE; FLUOROURACIL; GLIOMA; INJECTIONS; IRON; LACTIC ACID; MICROSPHERES; NEOPLASM TRANSPLANTATION; OXIDES; PARTICLE SIZE; POLYGLYCOLIC ACID; POLYMERS; RATS; RATS, SPRAGUE-DAWLEY; TRITIUM;

EID: 0036216566     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0939-6411(02)00011-5     Document Type: Article

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