Relationship between leptin, insulin resistance, insulin-like growth factor-1 and insulin-like growth factor binding protein-3 in patients with chronic kidney disease

Journal of International Medical Research

Volumn 36, Issue 3, 2008, Pages 522-528

  Atamer, A ^a   Ecder, S Alisir ^b   Akkus, Z ^c   Kocyigit, Y ^c   Atamer, Y ^c   Ilhan, N ^d   Ecder, T ^e  

^a Diyarbakir Training and Research Hospital   (Turkey)

^b GOZTEPE TRAINING AND RESEARCH HOSPITAL   (Turkey)

^c DICLE UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

^d FIRAT UNIVERSITY   (Turkey)

^e ISTANBUL UNIVERSITY   (Turkey)

Author keywords

Chronic kidney disease; Insulin like growth factor 1; Insulin resistance; Insulin like growth factor binding protein 3; Leptin

Indexed keywords

CREATININE; LEPTIN; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C; UREA;

ADULT; ARTICLE; BODY MASS; CHRONIC KIDNEY DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CREATININE BLOOD LEVEL; DIET RESTRICTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GLOMERULUS FILTRATION RATE; GLUCOSE BLOOD LEVEL; HOMEOSTASIS; HUMAN; IMMUNORADIOMETRIC ASSAY; INSULIN RESISTANCE; MALE; PROTEIN BLOOD LEVEL; UREA BLOOD LEVEL;

EID: 45149126674     PISSN: 03000605     EISSN: None     Source Type: Journal    
DOI: 10.1177/147323000803600317     Document Type: Article

References (22)

1. Zhang Y, Proenca R, Maffei M, et al: Positional cloning of the mouse obese gene and its human homologue. Nature 1994; 372: 425-432.
2. Beltowski J: Leptin and atherosclerosis. Atherosclerosis 2006; 189: 47-60.
3. Horoz M, Bolukbas FF, Bolukbas C, et al: The association of circulating leptin level with peripheral DNA damage in hemodialysis subjects. Clin Biochem 2006; 39: 918-922.
4. Merabet E, Dogogo-Jack S, Coyne DW, et al: Increased plasma leptin concentration in end-stage renal disease. J Clin Endocrinol Metab 1997; 82: 847-850.
5. Mlinar B, Marc J, Janez A, et al: Molecular mechanisms of insulin resistance and associated diseases. Clin Chim Acta 2007; 375: 20-35.
6. Cordido F, Perez-Fontán M, Rodriguez-Carmona A, et al: Relationship between the growth hormone-insulin like growth factor I axis and serum leptin in patients with chronic renal failure. Growth Horm IGF Res 2000; 10(suppl 2): S162.
7. LaPaglia N, Steiner J, Kirsteins L, et al: Leptin alters the response of the growth hormone releasing factor-growth hormone-insulin-like growth factor-I axis to fasting. J Endocrinol 1998; 159: 79-83.
8. Haspolat K, Ece A, Gürkan F, et al: Relationships between leptin, insulin, IGF-1 and IGFBP-3 in children with energy malnutrition. Clin Biochem 2007; 40: 201-205.
9. Powell DR: Effect of renal failure on the growth hormone-insulin-like growth factor axis. J Pediatrics 1997; 131(suppl): S13-S16.
10. Houang M, Cabrol S, Perin L, et al: Insulin-like growth factor-I (IGF-I), insulin-like growth factor binding proteins (IGFBP) and insulin-like growth factor type I receptor in children with various status of chronic renal failure. Growth Horm IGF Res 2000; 10: 332-341.
11. Nyombo. BL, Berard L, Murphy LJ: Free insulin-like growth factor 1 (IGF-1) in healthy subjects: relationship with IGF-binding proteins and insulin sensitivity. J Clin Endocrinol Metab 1997; 82: 2177-2181.
12. Blum WF: Insulin-like growth factors (IGFs) and IGF binding proteins in chronic renal failure: evidence for reduced secretion of IGFs. Acta Paediatr Scand Suppl 1991; 379: 24-31.
13. Levey AS, Eckardt KU, Tsukamoto Y, et al: Definition and classification of chronic kidney disease: a position statement from Kidney Disease: Improving Global Outcomes (KDIGO). Kidney Int 2005; 67: 2089-2100.
14. National Kidney Foundation: K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Am J Kidney Dis 2002; 39(2 suppl 1): S1-S266.
15. Sharma K, Considine RV, Michael B, et al: Plasma leptin is partly cleared by the kidney and is elevated in hemodialysis patients. Kidney Int 1997; 51: 1980-1985.
16. Risch L, Saely C, Hoefle G, et al: Relationship between glomerular filtration rate and the adipokines adiponectin, resistin and leptin in coronary patients with predominantly normal or mildly impaired renal function. Clin Chim Acta 2007; 376: 108-113.
17. Stenvinkel P, Heimbürger O, Lönnqvist F: Serum leptin concentrations correlate to plasma insulin concentrations independent of body fat content in chronic renal failure. Nephrol Dial Transplant 1997; 12: 1321-1325.
18. Stamatiadis DN, Chan JL, Cogswell R, et al: Elevated leptin fragments in renal failure correlate with BMI and haematopoiesis and are normalized by haemodialysis. Clin Endocrinol (Oxf) 2004; 60: 434-441.
19. Goumenou AG, Matalliotakis IM, Koumantakis GE, et al: The role of leptin in fertility. Eur J Obstet Gynecol Reprod Blol 2003; 106: 118-124.
20. Diaz E, Halhali A, Luna C, et al: Newborn birth weight correlates with placental zinc, umbilical insulin-like growth factor I, and leptin levels in preeclampsia. Arch Med Res 2002; 33: 40-47.
21. Fukuda I, Hizuka N, Okubo Y, et al: Changes in serum insulin-like growth factor binding protein-2, -3, and -6 levels in patients with chronic renal failure following renal transplantation. Growth Horm IGF Res 1998; 8: 481-486.
22. Jorkovská Z, Hodková M, Sazamová M, et al: Plasma levels of active and total ghrelin in renal failure: a relationship with GH/IGF-I axis. Growth Horm IGF Res 2005; 15: 369-376.