Relationships between leptin, insulin, IGF-1 and IGFBP-3 in children with energy malnutrition

Clinical Biochemistry

Volumn 40, Issue 3-4, 2007, Pages 201-205

  Haspolat, Kenan ^a   Ece, Aydin ^a   Gürkan, Fuat ^a   Atamer, Yildiz ^a   Tutanç, Murat ^a   Yolbaş, Ilyas ^a  

^a DICLE UNIVERSITY   (Turkey)

Author keywords

Children; IGF 1; IGFBP 3; Insulin; Leptin; Malnutrition

Indexed keywords

INSULIN; LEPTIN; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C;

ARM CIRCUMFERENCE; ARTICLE; BODY HEIGHT; BODY MASS; BODY WEIGHT; CALORIC INTAKE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DIET RESTRICTION; DISEASE ASSOCIATION; FEMALE; HORMONE BLOOD LEVEL; HUMAN; INFANT; INSULIN BLOOD LEVEL; MALE; MARASMUS; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SKINFOLD THICKNESS; STATISTICAL SIGNIFICANCE;

BODY HEIGHT; BODY MASS INDEX; BODY WEIGHT; FEMALE; HUMANS; INFANT; INSULIN; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3; INSULIN-LIKE GROWTH FACTOR I; LEPTIN; MALE; PROTEIN-ENERGY MALNUTRITION;

EID: 33846200833     PISSN: 00099120     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clinbiochem.2006.11.008     Document Type: Article

References (23)

1. Sawaya A.L., Martins P.A., Grillo L.P., and Florencio T.T. Long-term effects of early malnutrition on body weight regulation. Nutr. Rev. 62 (2004) S127-S133
2. Zamboni G., Denis D., Franco A., Roberta V., Dominque G., and Luciano T. Growth hormone-binding proteins in protein-energy malnutrition before and after nutritional rehabilitation. Pediatr. Res. 39 (1996) 410-414
3. Nazaimoon W., Osman A., Wu L.L., and Khalid B.A. Effects of iodine deficiency on insulin-like growth factor-I, insulin-like growth factor-binding protein-3 levels and height attainment in malnourished children. Clin. Endocrinol. 45 (1996) 79-83
4. Thissen J.P., Ketelslegers J.M., and Underwood L.E. Nutritional regulation of the insulin-like growth factors. Endocr. Rev. 15 (1994) 80-101
5. Zhang Y., Proenca R., Maffei M., Barone M., Leopold L., and Friedman C.M. Positional cloning of the mouse obese gene and its human homologue. Nature 372 (1994) 425-432
6. Mars M., de Graaf C., de Groot L.C., and Kok F.J. Decreases in fasting leptin and insulin concentrations after acute energy restriction and subsequent compensation in food intake. Am. J. Clin. Nutr. 81 (2005) 570-577
7. Ahima R.S., Prabakaran D., and Mantzoros C. Role of leptin in the neuroendocrine response to fasting. Nature 382 (1996) 250-252
8. Chan J.L., and Mantzoros C.S. Role of leptin in energy-deprivation states: normal human physiology and clinical implications for hypothalamic amenorrhea and anorexia nervosa. Lancet 366 (2005) 74-87
9. Wellhoenerk P., Fruehwald-Schultes B., Kern W., et al. Glucose metabolism rather than insulin is a main determinant of leptin secretion in humans. J. Clin. Endocrinol. Metab. 85 (2000) 1267-1271
10. Chan J.L., Heist K., DePaoli A.M., Veldhuis J.D., and Mantzoros C.S. The role of falling leptin levels in the neuroendocrine and metabolic adaptation to short-term starvation in healthy men. J. Clin. Invest. 111 (2003) 1409-1421
11. LaPaglia N., Steiner J., Kirsteins L., et al. Leptin alters the response of the growth hormone releasing factor-growth hormone-insulin-like growth factor-1 axis to fasting. J. Endocrinol. 159 (1998) 79-83
12. Haluzik M., Kabrt J., Nedvidkova J., et al. Relationship of serum leptin levels and selected nutritional parameters in patients with protein-caloric malnutrition. Nutrition 15 (1999) 829-834
13. Palacio A.C., Perez-Bravo F., Santos J.L., Schlesinger L., and Monckeberg F. Leptin levels and IgF-binding proteins in malnourished children: effect of weight gain. Nutrition 18 (2002) 17-19
14. Wellcome Trust Working Party. Classification of infantile malnutrition. Lancet ii (1970) 302-306
15. Neyzi O., Binyi{dotless}ldi{dotless}z P., and Alp H. Türk çocuklari{dotless}nda büyüme-gelişme normlari{dotless} 1.Tarti{dotless} ve boy deǧerleri [Growth charts for Turkish children 1. Body weight and height values]. İstanbul Ti{dotless}p. Fak. Mecm. [Journal of Istanbul Medical Faculty] Suppl. 41 (1978) 74-77
16. WHO working group. Use and interpretation of anthropometric indicators of nutritional status. Bull World Health Organ 64 (1986) 929-941
17. Kilic M., Taskin E., Ustundag B., and Aygun A.D. The evaluation of serum leptin level and other hormonal parameters in children with severe malnutrition. Clin. Biochem. 37 (2004) 382-387
18. Soliman A.T., ElZalabany M.M., Salama M., and Ansari B.M. Serum leptin concentrations during severe protein-energy malnutrition: correlation with growth parameters and endocrine function. Metabolism 49 (2000) 819-825
19. Park M.J., Kim H.S., Kang J.H., and Kim D.H. Serum levels of insulin-like growth factor-I (IGF-1), free IGF-1, IGF binding protein-I (IGF BP-I), IGF BP-3 and insulin in obese children. J. Pediatr. Endocrinol. Metab. 12 (1999) 139-144
20. Eckert E.D., Pomeroy C., Raymond N., et al. Leptin in anorexia nervosa. J. Clin. Endocrinol. Metab. 83 (1998) 791-794
21. Nyomba B.L.G., Berard L., and Murphy L.J. Free insulin-like growth factor 1 (IGF-1) in healthy subjects: relationship with IGF-Binding proteins and insulin sensitivity. J. Clin. Endocrinol. Metab. 82 (1997) 2177-2181
22. Maccario M., Ramunni J., Oleandri S.E., et al. Relationships between IGF-1 and age, gender, body mass, fat distribution, metabolic and hormonal variables in obese patients. Int. J. Obes. 23 (1999) 612-615
23. Orlowski C.C., Ooi G.T., Brown D.R., et al. Insulin rapidly inhibits insulin like growth factor binding protein-1 expression in HII-E rat hepatoma cells. Mol. Endocrinol. 5 (1991) 1180-1184