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Volumn 26, Issue 15, 2008, Pages 2428-2430

Does gefitinib shorten lung cancer survival? Chaos redux

Author keywords

[No Author keywords available]

Indexed keywords

DOCETAXEL; DOUBLE STRANDED DNA; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; GEFITINIB; PLACEBO; QUINAZOLINE; ANTINEOPLASTIC AGENT; EPIDERMAL GROWTH FACTOR RECEPTOR; QUINAZOLINE DERIVATIVE;

EID: 45149099893     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2008.16.0374     Document Type: Editorial
Times cited : (8)

References (26)
  • 1
    • 45149102984 scopus 로고    scopus 로고
    • Phase III trial of maintenance gefitinib or placebo after concurrent chemoradiotherapy and docetaxel consolidation in inoperable stage III non-small-cell lung cancer: SWOG S0023
    • Kelly K, Chansky K, Gaspar LE, et al: Phase III trial of maintenance gefitinib or placebo after concurrent chemoradiotherapy and docetaxel consolidation in inoperable stage III non-small-cell lung cancer: SWOG S0023. J Clin Oncol 26:2450-2456, 2008
    • (2008) J Clin Oncol , vol.26 , pp. 2450-2456
    • Kelly, K.1    Chansky, K.2    Gaspar, L.E.3
  • 2
    • 27544503230 scopus 로고    scopus 로고
    • Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small-cell lung cancer: Results from a randomised, placebo-controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer)
    • Thatcher N, Chang A, Parikh P, et al: Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small-cell lung cancer: Results from a randomised, placebo-controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer). Lancet 366:1527-1537, 2005
    • (2005) Lancet , vol.366 , pp. 1527-1537
    • Thatcher, N.1    Chang, A.2    Parikh, P.3
  • 3
    • 34047132314 scopus 로고    scopus 로고
    • Combination of EGFR gene copy number and protein expression predicts outcome for advanced non-small-cell lung cancer patients treated with gefitinib
    • Hirsch FR, Varella-Garcia M, Cappuzzo F, et al: Combination of EGFR gene copy number and protein expression predicts outcome for advanced non-small-cell lung cancer patients treated with gefitinib. Ann Oncol 18:752-760, 2007
    • (2007) Ann Oncol , vol.18 , pp. 752-760
    • Hirsch, F.R.1    Varella-Garcia, M.2    Cappuzzo, F.3
  • 4
    • 1542503746 scopus 로고    scopus 로고
    • Gefitinib in combination with gemcitabine and cisplatin in advanced non-small-cell lung cancer: A phase III trial - INTACT 1
    • Giaccone G, Herbst RS, Manegold C, et al: Gefitinib in combination with gemcitabine and cisplatin in advanced non-small-cell lung cancer: A phase III trial - INTACT 1. J Clin Oncol 22:777-784, 2004
    • (2004) J Clin Oncol , vol.22 , pp. 777-784
    • Giaccone, G.1    Herbst, R.S.2    Manegold, C.3
  • 5
    • 1542713370 scopus 로고    scopus 로고
    • Gefitinib in combination with paclitaxel and carboplatin in advanced non-small-cell lung cancer: A phase III trial - INTACT 2
    • Herbst RS, Giaccone G, Schiller JH, et al: Gefitinib in combination with paclitaxel and carboplatin in advanced non-small-cell lung cancer: A phase III trial - INTACT 2. J Clin Oncol 22:785-794, 2004
    • (2004) J Clin Oncol , vol.22 , pp. 785-794
    • Herbst, R.S.1    Giaccone, G.2    Schiller, J.H.3
  • 6
    • 24944440830 scopus 로고    scopus 로고
    • TRIBUTE: A phase III trial of erlotinib hydrochloride (OSI-774) combined with carboplatin and paclitaxel chemotherapy in advanced non-small-cell lung cancer
    • Herbst RS, Prager D, Hermann R, et al: TRIBUTE: A phase III trial of erlotinib hydrochloride (OSI-774) combined with carboplatin and paclitaxel chemotherapy in advanced non-small-cell lung cancer. J Clin Oncol 23:5892-5899, 2005
    • (2005) J Clin Oncol , vol.23 , pp. 5892-5899
    • Herbst, R.S.1    Prager, D.2    Hermann, R.3
  • 7
    • 34248140107 scopus 로고    scopus 로고
    • Phase III study of erlotinib in combination with cisplatin and gemcitabine in advanced non-small-cell lung cancer: The Tarceva Lung Cancer Investigation Trial
    • Gatzemeier U, Pluzanska A, Szczesna A, et al: Phase III study of erlotinib in combination with cisplatin and gemcitabine in advanced non-small-cell lung cancer: The Tarceva Lung Cancer Investigation Trial. J Clin Oncol 25:1545-1552, 2007
    • (2007) J Clin Oncol , vol.25 , pp. 1545-1552
    • Gatzemeier, U.1    Pluzanska, A.2    Szczesna, A.3
  • 8
    • 36849032852 scopus 로고    scopus 로고
    • Radiation-induced EGFR-signaling and control of DNA-damage repair
    • Rodemann HP, Dittmann K, Toulany M: Radiation-induced EGFR-signaling and control of DNA-damage repair. Int J Radiat Biol 83:781-791, 2007
    • (2007) Int J Radiat Biol , vol.83 , pp. 781-791
    • Rodemann, H.P.1    Dittmann, K.2    Toulany, M.3
  • 9
    • 26944449737 scopus 로고    scopus 로고
    • Radiation pneumonitis and pulmonary fibrosis in non-small-cell lung cancer: Pulmonary function, prediction, and prevention
    • Mehta V: Radiation pneumonitis and pulmonary fibrosis in non-small-cell lung cancer: Pulmonary function, prediction, and prevention. Int J Radiat Oncol Biol Phys 63:5-24, 2005
    • (2005) Int J Radiat Oncol Biol Phys , vol.63 , pp. 5-24
    • Mehta, V.1
  • 10
    • 0036468427 scopus 로고    scopus 로고
    • Severe interstitial pneumonitis associated with docetaxel administration
    • Read WL, Mortimer JE, Picus J: Severe interstitial pneumonitis associated with docetaxel administration. Cancer 94:847-853, 2002
    • (2002) Cancer , vol.94 , pp. 847-853
    • Read, W.L.1    Mortimer, J.E.2    Picus, J.3
  • 11
    • 2942550603 scopus 로고    scopus 로고
    • Risk factors for interstitial lung disease and predictive factors for tumor response in patients with advanced non-small cell lung cancer treated with gefitinib
    • Takano T, Ohe Y, Kusumoto M, et al: Risk factors for interstitial lung disease and predictive factors for tumor response in patients with advanced non-small cell lung cancer treated with gefitinib. Lung Cancer 45:93-104, 2004
    • (2004) Lung Cancer , vol.45 , pp. 93-104
    • Takano, T.1    Ohe, Y.2    Kusumoto, M.3
  • 12
    • 33646883312 scopus 로고    scopus 로고
    • Interstitial lung disease in patients with nonsmall-cell lung cancer treated with epidermal growth factor receptor inhibitors
    • Tsuboi M, Le Chevalier T: Interstitial lung disease in patients with nonsmall-cell lung cancer treated with epidermal growth factor receptor inhibitors. Med Oncol 23:161-170, 2006
    • (2006) Med Oncol , vol.23 , pp. 161-170
    • Tsuboi, M.1    Le Chevalier, T.2
  • 13
    • 32144433159 scopus 로고    scopus 로고
    • Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck
    • Bonner JA, Harari PM, Giralt J, et al: Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N Engl J Med 354:567-578, 2006
    • (2006) N Engl J Med , vol.354 , pp. 567-578
    • Bonner, J.A.1    Harari, P.M.2    Giralt, J.3
  • 14
    • 28844449401 scopus 로고    scopus 로고
    • Epidermal growth factor receptor mutations and gene amplification in non-small-cell lung cancer: Molecular analysis of the IDEAL/INTACT gefitinib trials
    • Bell DW, Lynch TJ, Haserlat SM, et al: Epidermal growth factor receptor mutations and gene amplification in non-small-cell lung cancer: Molecular analysis of the IDEAL/INTACT gefitinib trials. J Clin Oncol 23:8081-8092, 2005
    • (2005) J Clin Oncol , vol.23 , pp. 8081-8092
    • Bell, D.W.1    Lynch, T.J.2    Haserlat, S.M.3
  • 15
    • 1842509828 scopus 로고    scopus 로고
    • Bronchioloalveolar pathologic subtype and smoking history predict sensitivity to gefitinib in advanced non-small-cell lung cancer
    • Miller VA, Kris MG, Shah N, et al: Bronchioloalveolar pathologic subtype and smoking history predict sensitivity to gefitinib in advanced non-small-cell lung cancer. J Clin Oncol 22:1103-1109, 2004
    • (2004) J Clin Oncol , vol.22 , pp. 1103-1109
    • Miller, V.A.1    Kris, M.G.2    Shah, N.3
  • 16
    • 4444344330 scopus 로고    scopus 로고
    • EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
    • Pao W, Miller V, Zakowski M, et al: EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci U S A 101:13306-13311, 2004
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 13306-13311
    • Pao, W.1    Miller, V.2    Zakowski, M.3
  • 17
    • 15744372810 scopus 로고    scopus 로고
    • KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib
    • Pao W, Wang TY, Riely GJ, et al: KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib. PLoS Med 2:e17, 2005
    • (2005) PLoS Med , vol.2
    • Pao, W.1    Wang, T.Y.2    Riely, G.J.3
  • 18
    • 34249810645 scopus 로고    scopus 로고
    • KRAS mutation is an important predictor of resistance to therapy with epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer
    • Massarelli E, Varella-Garcia M, Tang X, et al: KRAS mutation is an important predictor of resistance to therapy with epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer. Clin Cancer Res 13:2890-2896, 2007
    • (2007) Clin Cancer Res , vol.13 , pp. 2890-2896
    • Massarelli, E.1    Varella-Garcia, M.2    Tang, X.3
  • 19
    • 37349092482 scopus 로고    scopus 로고
    • Gefitinib (IRESSA) versus docetaxel in patients with locally advanced or metastatic non-small-cell lung cancer pretreated with platinum based chemotherapy: A randomized, open-label phase III study (INTEREST)
    • suppl
    • Douillard J-Y, Kim E, Hirsh V, et al: Gefitinib (IRESSA) versus docetaxel in patients with locally advanced or metastatic non-small-cell lung cancer pretreated with platinum based chemotherapy: A randomized, open-label phase III study (INTEREST). J Thorac Oncol 2:S305, 2007 (suppl)
    • (2007) J Thorac Oncol , vol.2
    • Douillard, J.-Y.1    Kim, E.2    Hirsh, V.3
  • 20
    • 24944578615 scopus 로고    scopus 로고
    • Epidermal growth factor receptor tyrosine kinase inhibitors plus chemotherapy: Case closed or is the jury still out?
    • Gandara DR, Gumerlock PH: Epidermal growth factor receptor tyrosine kinase inhibitors plus chemotherapy: Case closed or is the jury still out? J Clin Oncol 23:5856-5858, 2005
    • (2005) J Clin Oncol , vol.23 , pp. 5856-5858
    • Gandara, D.R.1    Gumerlock, P.H.2
  • 21
    • 34147105416 scopus 로고    scopus 로고
    • Epidermal growth factor receptor inhibitors plus chemotherapy in non-small-cell lung cancer: Biologic rationale for combination strategies
    • suppl 2
    • Gandara DR, Davies AM, Gautschi O, et al: Epidermal growth factor receptor inhibitors plus chemotherapy in non-small-cell lung cancer: Biologic rationale for combination strategies. Clin Lung Cancer 8:S61-S67, 2007 (suppl 2)
    • (2007) Clin Lung Cancer , vol.8
    • Gandara, D.R.1    Davies, A.M.2    Gautschi, O.3
  • 22
    • 0030801361 scopus 로고    scopus 로고
    • Unliganded epidermal growth factor receptor dimerization induced by direct interaction of quinazolines with the ATP binding site
    • Arteaga CL, Ramsey TT, Shawver LK, et al: Unliganded epidermal growth factor receptor dimerization induced by direct interaction of quinazolines with the ATP binding site. J Biol Chem 272:23247-23254, 1997
    • (1997) J Biol Chem , vol.272 , pp. 23247-23254
    • Arteaga, C.L.1    Ramsey, T.T.2    Shawver, L.K.3
  • 23
    • 0037388251 scopus 로고    scopus 로고
    • ZD1839, a specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, induces the formation of inactive EGFR/HER2 and EGFR/HER3 heterodimers and prevents heregulin signaling in HER2-overexpressing breast cancer cells
    • Anido J, Matar P, Albanell J, et al: ZD1839, a specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, induces the formation of inactive EGFR/HER2 and EGFR/HER3 heterodimers and prevents heregulin signaling in HER2-overexpressing breast cancer cells. Clin Cancer Res 9:1274-1283, 2003
    • (2003) Clin Cancer Res , vol.9 , pp. 1274-1283
    • Anido, J.1    Matar, P.2    Albanell, J.3
  • 24
    • 0035423120 scopus 로고    scopus 로고
    • Signaling-inactive epidermal growth factor receptor/ligand complexes in intact carcinoma cells by quinazoline tyrosine kinase inhibitors
    • Lichtner RB, Menrad A, Sommer A, et al: Signaling-inactive epidermal growth factor receptor/ligand complexes in intact carcinoma cells by quinazoline tyrosine kinase inhibitors. Cancer Res 61:5790-5795, 2001
    • (2001) Cancer Res , vol.61 , pp. 5790-5795
    • Lichtner, R.B.1    Menrad, A.2    Sommer, A.3
  • 25
    • 24944497744 scopus 로고    scopus 로고
    • Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small-cell lung cancer treated with chemotherapy alone and in combination with erlotinib
    • Eberhard DA, Johnson BE, Amler LC, et al: Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small-cell lung cancer treated with chemotherapy alone and in combination with erlotinib. J Clin Oncol 23:5900-5909, 2005
    • (2005) J Clin Oncol , vol.23 , pp. 5900-5909
    • Eberhard, D.A.1    Johnson, B.E.2    Amler, L.C.3
  • 26
    • 19744365702 scopus 로고    scopus 로고
    • A small molecule-kinase interaction map for clinical kinase inhibitors
    • Fabian MA, Biggs WH 3rd, Treiber DK, et al: A small molecule-kinase interaction map for clinical kinase inhibitors. Nat Biotechnol 23:329-336, 2005
    • (2005) Nat Biotechnol , vol.23 , pp. 329-336
    • Fabian, M.A.1    Biggs 3rd, W.H.2    Treiber, D.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.