메뉴 건너뛰기




Volumn 93, Issue 6, 2008, Pages 2089-2096

Evidence for insulin suppression of baseline luteinizing hormone in women with polycystic ovarian syndrome and normal women

Author keywords

[No Author keywords available]

Indexed keywords

GONADORELIN; INSULIN; LUTEINIZING HORMONE; TESTOSTERONE;

EID: 45149086567     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2007-2656     Document Type: Article
Times cited : (61)

References (36)
  • 1
    • 0018840897 scopus 로고
    • The polycystic ovary syndrome
    • Yen SS 1980 The polycystic ovary syndrome. Clin Endocrinol (Oxf) 12:177-207
    • (1980) Clin Endocrinol (Oxf) , vol.12 , pp. 177-207
    • Yen, S.S.1
  • 2
    • 0017068476 scopus 로고
    • Characterization of the inappropriate gonadotropin secretion in polycystic ovary syndrome
    • Rebar R, Judd HL, Yen SS, Rakoff J, Vandenberg G, Naftolin F 1976 Characterization of the inappropriate gonadotropin secretion in polycystic ovary syndrome. J Clin Invest 57:1320-1329
    • (1976) J Clin Invest , vol.57 , pp. 1320-1329
    • Rebar, R.1    Judd, H.L.2    Yen, S.S.3    Rakoff, J.4    Vandenberg, G.5    Naftolin, F.6
  • 3
    • 0346186090 scopus 로고    scopus 로고
    • The Rotterdam ESHRE/ASRM-Sponsored PCOS concensus workshop group 2004 Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). Hum Reprod 19:41-47
    • The Rotterdam ESHRE/ASRM-Sponsored PCOS concensus workshop group 2004 Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). Hum Reprod 19:41-47
  • 4
    • 0020421953 scopus 로고
    • Enhanced disparity of gonadotropin secretion by estrone in women with polycystic ovarian disease
    • Chang RJ, Mandel FP, Lu JK, Judd HL 1982 Enhanced disparity of gonadotropin secretion by estrone in women with polycystic ovarian disease. J Clin Endocrinol Metab 54:490-494
    • (1982) J Clin Endocrinol Metab , vol.54 , pp. 490-494
    • Chang, R.J.1    Mandel, F.P.2    Lu, J.K.3    Judd, H.L.4
  • 5
    • 0034523425 scopus 로고    scopus 로고
    • Polycystic ovarian syndrome: Evidence that flutamide restores sensitivity of the gonadotropin-releasing hormone pulse generator to inhibition by estradiol and progesterone
    • Eagleson CA, Gingrich MB, Pastor CL, Arora TK, Burt CM, Evans WS, Marshall JC 2000 Polycystic ovarian syndrome: evidence that flutamide restores sensitivity of the gonadotropin-releasing hormone pulse generator to inhibition by estradiol and progesterone. J Clin Endocrinol Metab 85:4047-4052
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 4047-4052
    • Eagleson, C.A.1    Gingrich, M.B.2    Pastor, C.L.3    Arora, T.K.4    Burt, C.M.5    Evans, W.S.6    Marshall, J.C.7
  • 6
    • 0031765313 scopus 로고    scopus 로고
    • Polycystic ovary syndrome: Evidence for reduced sensitivity of the gonadotropin-releasing hormone pulse generator to inhibition by estradiol and progesterone
    • Pastor CL, Griffin-Korf ML, Aloi JA, Evans WS, Marshall JC 1998 Polycystic ovary syndrome: evidence for reduced sensitivity of the gonadotropin-releasing hormone pulse generator to inhibition by estradiol and progesterone. J Clin Endocrinol Metab 83:582-590
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 582-590
    • Pastor, C.L.1    Griffin-Korf, M.L.2    Aloi, J.A.3    Evans, W.S.4    Marshall, J.C.5
  • 7
    • 0019443286 scopus 로고
    • Insulin enhancement of luteinizing hormone and follicle-stimulating hormone release by cultured pituitary cells
    • Adashi EY, Hsueh AJ, Yen SS 1981 Insulin enhancement of luteinizing hormone and follicle-stimulating hormone release by cultured pituitary cells. Endocrinology 108:1441-1449
    • (1981) Endocrinology , vol.108 , pp. 1441-1449
    • Adashi, E.Y.1    Hsueh, A.J.2    Yen, S.S.3
  • 10
    • 0024590991 scopus 로고
    • Insulin administration alters gonadal steroid metabolism independent of changes in gonadotropin secretion in insulin-resistant women with the polycystic ovary syndrome
    • Dunaif A, Graf M 1989 Insulin administration alters gonadal steroid metabolism independent of changes in gonadotropin secretion in insulin-resistant women with the polycystic ovary syndrome. J Clin Invest 83:23-29
    • (1989) J Clin Invest , vol.83 , pp. 23-29
    • Dunaif, A.1    Graf, M.2
  • 11
    • 0023102652 scopus 로고
    • The effects of hyperinsulinemia on serum testosterone, progesterone, dehydroepiandrosterone sulfate, and cortisol levels in normal women and in a woman with hyperandrogenism, insulin resistance, and acanthosis nigricans
    • Nestler JE, Clore JN, Strauss 3rd JF, Blackard WG 1987 The effects of hyperinsulinemia on serum testosterone, progesterone, dehydroepiandrosterone sulfate, and cortisol levels in normal women and in a woman with hyperandrogenism, insulin resistance, and acanthosis nigricans. J Clin Endocrinol Metab 64:180-184
    • (1987) J Clin Endocrinol Metab , vol.64 , pp. 180-184
    • Nestler, J.E.1    Clore, J.N.2    Strauss 3rd, J.F.3    Blackard, W.G.4
  • 12
    • 17844375675 scopus 로고    scopus 로고
    • Luteinizing hormone secretion is not influenced by insulin infusion in women with polycystic ovary syndrome despite improved insulin sensitivity during pioglitazone treatment
    • Mehta RV, Patel KS, Coffler MS, Dahan MH, Yoo RY, Archer JS, Malcom PJ, Chang RJ 2005 Luteinizing hormone secretion is not influenced by insulin infusion in women with polycystic ovary syndrome despite improved insulin sensitivity during pioglitazone treatment. J Clin Endocrinol Metab 90:2136-2141
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 2136-2141
    • Mehta, R.V.1    Patel, K.S.2    Coffler, M.S.3    Dahan, M.H.4    Yoo, R.Y.5    Archer, J.S.6    Malcom, P.J.7    Chang, R.J.8
  • 14
    • 0029796476 scopus 로고    scopus 로고
    • Decreases in ovarian cytochrome P450c17α activity and serum free testosterone after reduction of insulin secretion in polycystic ovary syndrome
    • Nestler JE, Jakubowicz DJ 1996 Decreases in ovarian cytochrome P450c17α activity and serum free testosterone after reduction of insulin secretion in polycystic ovary syndrome. N Engl J Med 335:617-623
    • (1996) N Engl J Med , vol.335 , pp. 617-623
    • Nestler, J.E.1    Jakubowicz, D.J.2
  • 15
    • 0029795871 scopus 로고    scopus 로고
    • The insulin-sensitizing agent troglitazone improves metabolic and reproductive abnormalities in the polycystic ovary syndrome
    • Dunaif A, Scott D, Finegood D, Quintana B, Whitcomb R 1996 The insulin-sensitizing agent troglitazone improves metabolic and reproductive abnormalities in the polycystic ovary syndrome. J Clin Endocrinol Metab 81:3299-3306
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 3299-3306
    • Dunaif, A.1    Scott, D.2    Finegood, D.3    Quintana, B.4    Whitcomb, R.5
  • 16
    • 0028315971 scopus 로고
    • Metformin therapy in polycystic ovary syndrome reduces hyperinsulinemia, insulin resistance, hyperandrogenemia, and systolic blood pressure, while facilitating normal menses and pregnancy
    • Velazquez EM, Mendoza S, Hamer T, Sosa F, Glueck CJ 1994 Metformin therapy in polycystic ovary syndrome reduces hyperinsulinemia, insulin resistance, hyperandrogenemia, and systolic blood pressure, while facilitating normal menses and pregnancy. Metabolism 43:647-654
    • (1994) Metabolism , vol.43 , pp. 647-654
    • Velazquez, E.M.1    Mendoza, S.2    Hamer, T.3    Sosa, F.4    Glueck, C.J.5
  • 17
    • 0033346579 scopus 로고    scopus 로고
    • Restoration of reproductive potential by lifestyle modification in obese polycystic ovary syndrome: Role of insulin sensitivity and luteinizing hormone
    • Huber-Buchholz MM, Carey DG, Norman RJ 1999 Restoration of reproductive potential by lifestyle modification in obese polycystic ovary syndrome: role of insulin sensitivity and luteinizing hormone. J Clin Endocrinol Metab 84: 1470-1474
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 1470-1474
    • Huber-Buchholz, M.M.1    Carey, D.G.2    Norman, R.J.3
  • 18
    • 17744400090 scopus 로고    scopus 로고
    • Effect of long-term treatment with metformin added to hypocaloric diet on body composition, fat distribution, and androgen and insulin levels in abdominally obese women with and without the polycystic ovary syndrome
    • Pasquali R, Gambineri A, Biscotti D, Vicennati V, Gagliardi L, Colitta D, Fiorini S, Cognigni GE, Filicori M, Morselli-Labate AM 2000 Effect of long-term treatment with metformin added to hypocaloric diet on body composition, fat distribution, and androgen and insulin levels in abdominally obese women with and without the polycystic ovary syndrome. J Clin Endocrinol Metab 85:2767-2774
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 2767-2774
    • Pasquali, R.1    Gambineri, A.2    Biscotti, D.3    Vicennati, V.4    Gagliardi, L.5    Colitta, D.6    Fiorini, S.7    Cognigni, G.E.8    Filicori, M.9    Morselli-Labate, A.M.10
  • 19
    • 0033694153 scopus 로고    scopus 로고
    • The decrease in luteinizing hormone secretion in response to weight reduction is inversely related to the severity of insulin resistance in overweight women
    • Butzow TL, Lehtovirta M, Siegberg R, Hovatta O, Koistinen R, Seppala M, Apter D 2000 The decrease in luteinizing hormone secretion in response to weight reduction is inversely related to the severity of insulin resistance in overweight women. J Clin Endocrinol Metab 85:3271-3275
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 3271-3275
    • Butzow, T.L.1    Lehtovirta, M.2    Siegberg, R.3    Hovatta, O.4    Koistinen, R.5    Seppala, M.6    Apter, D.7
  • 20
    • 0032937815 scopus 로고    scopus 로고
    • Effect of troglitazone on endocrine and ovulatory performance in women with insulin resistance-related polycystic ovary syndrome
    • Hasegawa I, Murakawa H, Suzuki M, Yamamoto Y, Kurabayashi T, Tanaka K 1999 Effect of troglitazone on endocrine and ovulatory performance in women with insulin resistance-related polycystic ovary syndrome. Fertil Steril 71:323-327
    • (1999) Fertil Steril , vol.71 , pp. 323-327
    • Hasegawa, I.1    Murakawa, H.2    Suzuki, M.3    Yamamoto, Y.4    Kurabayashi, T.5    Tanaka, K.6
  • 21
    • 0030745921 scopus 로고    scopus 로고
    • Menstrual cyclicity after metformin therapy in polycystic ovary syndrome
    • Velazquez E, Acosta A, Mendoza SG 1997 Menstrual cyclicity after metformin therapy in polycystic ovary syndrome. Obstet Gynecol 90:392-395
    • (1997) Obstet Gynecol , vol.90 , pp. 392-395
    • Velazquez, E.1    Acosta, A.2    Mendoza, S.G.3
  • 22
    • 29144444654 scopus 로고    scopus 로고
    • Metabolic and ovarian effects of rosiglitazone treatment for 12 weeks in insulin-resistant women with polycystic ovary syndrome
    • Cataldo NA, Abbasi F, McLaughlin TL, Basina M, Fechner PY, Giudice LC, Reaven GM 2006 Metabolic and ovarian effects of rosiglitazone treatment for 12 weeks in insulin-resistant women with polycystic ovary syndrome. Hum Reprod 21:109-120
    • (2006) Hum Reprod , vol.21 , pp. 109-120
    • Cataldo, N.A.1    Abbasi, F.2    McLaughlin, T.L.3    Basina, M.4    Fechner, P.Y.5    Giudice, L.C.6    Reaven, G.M.7
  • 24
    • 34347225149 scopus 로고    scopus 로고
    • Lack of effect of short-term diazoxide administration on luteinizing hormone secretion in women with polycystic ovary syndrome
    • Evans WS, Taylor AE, Boyd DG, Johnson ML, Matt DW, Jimenez Y, Nestler JE 2007 Lack of effect of short-term diazoxide administration on luteinizing hormone secretion in women with polycystic ovary syndrome. Fertil Steril 88:118-124
    • (2007) Fertil Steril , vol.88 , pp. 118-124
    • Evans, W.S.1    Taylor, A.E.2    Boyd, D.G.3    Johnson, M.L.4    Matt, D.W.5    Jimenez, Y.6    Nestler, J.E.7
  • 25
    • 0345305400 scopus 로고    scopus 로고
    • Increased luteinizing hormone secretion in women with polycystic ovary syndrome is unaltered by prolonged insulin infusion
    • Patel K, Coffler MS, Dahan MH, Yoo RY, Lawson MA, Malcom PJ, Chang RJ 2003 Increased luteinizing hormone secretion in women with polycystic ovary syndrome is unaltered by prolonged insulin infusion. J Clin Endocrinol Metab 88:5456-5461
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 5456-5461
    • Patel, K.1    Coffler, M.S.2    Dahan, M.H.3    Yoo, R.Y.4    Lawson, M.A.5    Malcom, P.J.6    Chang, R.J.7
  • 26
    • 0842265978 scopus 로고    scopus 로고
    • Relationship of GnRH-stimulated LH release to episodic LH secretion and baseline endocrine-metabolic measures in women with polycystic ovary syndrome
    • Patel K, Coffler MS, Dahan MH, Malcom PJ, Deutsch R, Chang RJ 2004 Relationship of GnRH-stimulated LH release to episodic LH secretion and baseline endocrine-metabolic measures in women with polycystic ovary syndrome. Clin Endocrinol (Oxf) 60:67-74
    • (2004) Clin Endocrinol (Oxf) , vol.60 , pp. 67-74
    • Patel, K.1    Coffler, M.S.2    Dahan, M.H.3    Malcom, P.J.4    Deutsch, R.5    Chang, R.J.6
  • 27
    • 0030698381 scopus 로고    scopus 로고
    • Inappropriate gonadotropin secretion in polycystic ovary syndrome: Influence of adiposity
    • Arroyo A, Laughlin GA, Morales AJ, Yen SS 1997 Inappropriate gonadotropin secretion in polycystic ovary syndrome: influence of adiposity. J Clin Endocrinol Metab 82:3728-3733
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 3728-3733
    • Arroyo, A.1    Laughlin, G.A.2    Morales, A.J.3    Yen, S.S.4
  • 28
    • 33646029436 scopus 로고    scopus 로고
    • Inverse relationship between luteinizing hormone and body mass index in polycystic ovarian syndrome: Investigation of hypothalamic and pituitary contributions
    • Pagan YL, Srouji SS, Jimenez Y, Emerson A, Gill S, Hall JE 2006 Inverse relationship between luteinizing hormone and body mass index in polycystic ovarian syndrome: investigation of hypothalamic and pituitary contributions. J Clin Endocrinol Metab 91:1309-1316
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 1309-1316
    • Pagan, Y.L.1    Srouji, S.S.2    Jimenez, Y.3    Emerson, A.4    Gill, S.5    Hall, J.E.6
  • 29
    • 2442701352 scopus 로고    scopus 로고
    • Energy balance and reproduction
    • Schneider JE 2004 Energy balance and reproduction. Physiol Behav 81:289-317
    • (2004) Physiol Behav , vol.81 , pp. 289-317
    • Schneider, J.E.1
  • 30
    • 34248593022 scopus 로고    scopus 로고
    • Effects of metformin treatment in women with polycystic ovary syndrome depends on insulin resistance
    • Nawrocka J, Starczewski A 2007 Effects of metformin treatment in women with polycystic ovary syndrome depends on insulin resistance. Gynecol Endocrinol 23:231-237
    • (2007) Gynecol Endocrinol , vol.23 , pp. 231-237
    • Nawrocka, J.1    Starczewski, A.2
  • 31
    • 33847133380 scopus 로고    scopus 로고
    • Polycystic ovary syndrome: Early detection in the adolescent
    • Chang RJ, Coffler MS 2007 Polycystic ovary syndrome: early detection in the adolescent. Clin Obstet Gynecol 50:178-187
    • (2007) Clin Obstet Gynecol , vol.50 , pp. 178-187
    • Chang, R.J.1    Coffler, M.S.2
  • 32
    • 33745249573 scopus 로고    scopus 로고
    • The origins and sequelae of abnormal neuroendocrine function in polycystic ovary syndrome
    • Blank SK, McCartney CR, Marshall JC 2006 The origins and sequelae of abnormal neuroendocrine function in polycystic ovary syndrome. Hum Reprod Update 12:351-361
    • (2006) Hum Reprod Update , vol.12 , pp. 351-361
    • Blank, S.K.1    McCartney, C.R.2    Marshall, J.C.3
  • 33
    • 0031156840 scopus 로고    scopus 로고
    • Serum leptin levels in women with polycystic ovary syndrome: The role of insulin resistance/hyperinsulinemia
    • Laughlin GA, Morales AJ, Yen SS 1997 Serum leptin levels in women with polycystic ovary syndrome: the role of insulin resistance/hyperinsulinemia. J Clin Endocrinol Metab 82:1692-1696
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 1692-1696
    • Laughlin, G.A.1    Morales, A.J.2    Yen, S.S.3
  • 34
    • 35248838860 scopus 로고    scopus 로고
    • Leptin secretory burst mass correlates with body mass index and insulin in normal women but not in women with polycystic ovary syndrome
    • Iuorno MJ, Islam LZ, Veldhuis PP, Boyd DG, Farhy LS, Johnson ML, Nestler JE, Evans WS 2007 Leptin secretory burst mass correlates with body mass index and insulin in normal women but not in women with polycystic ovary syndrome. Metabolism 56:1561-1565
    • (2007) Metabolism , vol.56 , pp. 1561-1565
    • Iuorno, M.J.1    Islam, L.Z.2    Veldhuis, P.P.3    Boyd, D.G.4    Farhy, L.S.5    Johnson, M.L.6    Nestler, J.E.7    Evans, W.S.8
  • 35
    • 34447344074 scopus 로고    scopus 로고
    • Influence of hypo- and hyperglycaemia on plasma leptin concentrations in healthy women and in women with polycystic ovary syndrome
    • Ludwig AK, Weiss JM, Tauchert S, Dietze T, Rudolf S, Diedrich K, Peters A, Oltmanns KM 2007 Influence of hypo- and hyperglycaemia on plasma leptin concentrations in healthy women and in women with polycystic ovary syndrome. Hum Reprod 22:1555-1561
    • (2007) Hum Reprod , vol.22 , pp. 1555-1561
    • Ludwig, A.K.1    Weiss, J.M.2    Tauchert, S.3    Dietze, T.4    Rudolf, S.5    Diedrich, K.6    Peters, A.7    Oltmanns, K.M.8
  • 36
    • 34248340020 scopus 로고    scopus 로고
    • The adiponectin-to-leptin ratio in women with polycystic ovary syndrome: Relation to insulin resistance and proinflammatory markers
    • Xita N, Papassotiriou I, Georgiou I, Vounatsou M, Margeli A, Tsatsoulis A 2007 The adiponectin-to-leptin ratio in women with polycystic ovary syndrome: relation to insulin resistance and proinflammatory markers. Metabolism 56:766-771
    • (2007) Metabolism , vol.56 , pp. 766-771
    • Xita, N.1    Papassotiriou, I.2    Georgiou, I.3    Vounatsou, M.4    Margeli, A.5    Tsatsoulis, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.