Terbutaline enantiomer separation and quantification by complexation and field asymmetric ion mobility spectrometry-tandem mass spectrometry

Analytical Chemistry

Volumn 80, Issue 11, 2008, Pages 4133-4140

  Mie, Axel ^a   Ray, Andrew ^b   Axelsson, Bengt Olof ^c   Jörnten Karlsson, Magnus ^c   Reimann, Curt T ^a  

^a LUND UNIVERSITY   (Sweden)

^b ASTRAZENECA   (United Kingdom)

^c ASTRAZENECA R AND D   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

AMINATION; AMINES; AMINO ACIDS; CHARGED PARTICLES; CHEMICAL MODIFICATION; CHEMOTHERAPY; CHIRALITY; DRUG DELIVERY; DRUG DOSAGE; DRUG THERAPY; ELECTRONS; ENANTIOMERS; HEALTH; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOMERS; MASS SPECTROMETERS; MASS SPECTROMETRY; METAL ANALYSIS; METAL IONS; ORGANIC ACIDS; SEPARATION; SPECTROMETERS; SPECTROMETRY; SPECTRUM ANALYSIS; TELLURIUM COMPOUNDS;

CHIRAL SEPARATIONS; DIASTEREOMERIC COMPLEXES; ELECTROSPRAY (ES); ENANTIOMER SEPARATIONS; HIGH FIELD ASYMMETRIC WAVEFORM ION MOBILITY SPECTROMETRY (FAIMS); ION MOBILITY SPECTROMETRY (IMS); NEW APPROACHES; TANDEM MASS SPECTROMETRY (MS/MS); TERBUTALINE;

IONS;

METAL ION; TERBUTALINE;

AMINO ACID ANALYSIS; ANALYTIC METHOD; ARTICLE; CHIRALITY; COMPLEX FORMATION; DIASTEREOISOMER; DRUG DETERMINATION; ENANTIOMER; FIELD ASYMMETRIC ION MOBILITY SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETER; QUANTITATIVE ANALYSIS; SEPARATION TECHNIQUE; TANDEM MASS SPECTROMETRY;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ELECTROPHORESIS, CAPILLARY; SPECTRUM ANALYSIS; STEREOISOMERISM; TANDEM MASS SPECTROMETRY; TERBUTALINE;

EID: 44949240697     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac702262k     Document Type: Article

References (43)

1. De Camp, W. H. Chirality 1989, 1, 2-6.
2. Caner, H.; Groner, E.; Levy, L.; Agranat, I. Drug Discov. Today 2004, 9, 105-110.
3. Anonymous Guidance for Industry: Q3A(R2) Impurities in New Drug Substances. The International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH), 2006.
4. Anonymous Guidance for Industry: Q6A Specifications: test procedures and acceptance criteria for new drug substances and new drug products. The International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH). 1999.
5. Ward, T. J.; Hamburg, D.-M. Anal. Chem. 2004, 76, 4635-4644.
6. Wenzel, T. J.; Wilcox, J. D. Chirality 2003, 15, 256-270.
7. Gubitz, G.; Schmid, M. G. Biopharm. Drug Dispos. 2001, 22, 291-336.
8. Zarbl, E.; Lammerhofer, M.; Woschek, A.; Hammerschmidt, F.; Parenti, C.; Cannazza, G.; Lindner, W. J. Sep. Sci. 2002, 25, 1269-1283.
9. Constantin, S.; Bicker, W.; Zarbl, E.; Lammerhofer, M.; Lindner, W. Electrophoresis 2003, 24, 1668-1679.
10. Hebenstreit, D.; Bicker, W.; Laemmerhofer, M.; Lindner, W. Electrophoresis 2004, 25, 277-289.
11. Schweitz, L.; Andersson, L. I.; Nilsson, S. Anal. Chim. Acta 2001, 435, 43-47.
12. Tao, W. A.; Zhang, D.; Wang, F.; Thomas, P. D.; Cooks, R. G. Anal. Chem. 1999, 71, 4427-4429.
13. Schug, K. A.; Lindner, W. J. Sep. Sci. 2005, 28, 1932-1955.
14. Dwivedi, P.; Wu, C.; Matz, L. M.; Clowers, B. H.; Seims, W. F.; Hill, H. H., Jr. Anal. Chem. 2006, 78, 8200-8206.
15. Thompson, R. J. Liq. Chromatogr. Relat. Technol. 2005, 28, 1215-1231.
16. Blomberg, L. G.; Wan, H. Electrophoresis 2000, 21, 1940-1952.
17. Stalcup, A. M.; Gahm, K. H. J. Microcolumn Sep. 1996, 8, 145-150.
18. Zhu, W.; Vigh, G. J. Chromatogr., A 2003, 987, 459-466.
19. Schurig, V. J. Chromatogr., A 2001, 906, 275-299.
20. Mie, A.; Jörntén-Karlsson, M.; Axelsson, B.-O.; Ray, A.; Reimann, C. T. Anal. Chem. 2007, 79, 2850-2858.
21. Lam, F.; Elliott, J.; Jones, J. S.; Katz, M.; Knuppel, R. A.; Morrison, J.; Newman, R.; Phelan, J.; Willcourt, R. Obstet. Gynecol. Surv. 1998, 53, 85-95.
22. Andersson, M. E.; Aslan, D.; Clarke, A.; Roeraade, J.; Hagman, G. J. Chromatogr., A 2003, 1005, 83-101.
23. Ye, Y. K.; Stringham, R. W. Chirality 2006, 18, 519-530.
24. Stringham, R. W.; Ye, Y. K. J. Chromatogr., A 2006, 1101, 86-93.
25. Aboul-Enein, H. Y.; Efstatiade, M. D.; Baiulescu, G. E. Electrophoresis 1999, 20, 2686-2690.
26. Westall, A.; Malmstroem, T.; Petersson, P. Electrophoresis 2006, 27, 859-864.
27. Hedeland, Y.; Lehtinen, J.; Pettersson, C. J. Chromatogr., A 2007, 1141, 287-294.
28. Yang, G. S.; Chen, D. M.; Yang, Y.; Tang, B.; Gao, J. J.; Aboul-Enein, H. Y.; Koppenhoefer, B. Chromatographia 2005, 62, 441-445.
29. Servais, A.-C.; Fillet, M.; Chiap, P.; Dewe, W.; Hubert, P.; Crommen, J. Electrophoresis 2004 25, 2701-2710.
30. Ivanyi, R.; Jicsinszky, L.; Juvancz, Z.; Roos, N.; Otta, K.; Szejtli, J. Electrophoresis 2004, 25, 2675-2686.
31. Kim, K. H.; Kim, H. J.; Kim, J. H.; Lee, J. H.; Lee, S. C. Chromatographia 2001, 53, 334-337.
32. Purves, R. W.; Barnett, D. A.; Ells, B.; Guevremont, R. J. Am. Soc. Mass Spectrom. 2000, 11, 738-745.
33. Purves, R. W.; Barnett, D. A.; Ells, B.; Guevremont, R. J. Am. Soc. Mass Spectrom. 2001, 12, 894-901.
34. Shvartsburg, A. A.; Li, F.; Tang, K.; Smith, R. D. Anal. Chem. 2007, 79, 1523-1528.
35. Purves, R. W.; Barnett, D. A.; Ells, B.; Guevremont, R. Rapid Commun. Mass Spectrom. 2001, 15, 1453-1456.
36. Shvartsburg, A. A.; Li, F.; Tang, K.; Smith, R. D. Anal. Chem. 2006, 78, 3304-3315.
37. Robinson, E. W.; Leib, R. D.; Williams, E. R. J. Am. Soc. Mass Spectrom. 2006, 17, 1469-1479.
38. Robinson, E. W.; Sellon, R. E.; Williams, E. R. Int. J. Mass Spectrom. 2007, 259, 87-95.
39. Kolakowski, B. M.; McCooeye, M. A.; Mester, Z. Rapid Commun. Mass Spectrom. 2006, 20, 3319-3329.
40. Gabryelski, W.; Froese, K. L. J. Am. Soc. Mass Spectrom. 2003, 14, 265-277.
41. Levin, D. S.; Vouros, P.; Miller, R. A.; Nazarov, E. G. J. Am. Soc. Mass Spectrom. 2007, 18, 502-511.
42. Tao, W. A.; Gozzo, F. C.; Cooks, R. G. Anal. Chem. 2001, 73, 1692-1698.
43. Young, B. L.; Cooks, R. G.; Madden, M. C.; Bair, M.; Jia, J.; Aubry, A.-F.; Miller, S. A. J. Pharm. Biomed. Anal. 2007, 43, 1602-1608.