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Volumn 9, Issue 5, 2008, Pages 501-504

Serotonin type 3 receptor genes: HTR3A, B, C, D, E

Author keywords

[No Author keywords available]

Indexed keywords

ALOSETRON; ANTIEMETIC AGENT; ANTINEOPLASTIC AGENT; DOLASETRON MESILATE; GRANISETRON; ONDANSETRON; PALONOSETRON; PAROXETINE; SEROTONIN 3 ANTAGONIST; SEROTONIN 3 RECEPTOR; SEROTONIN 3A RECEPTOR; SEROTONIN 3B RECEPTOR; SEROTONIN 3C RECEPTOR; SEROTONIN 3D RECEPTOR; SEROTONIN 3E RECEPTOR; TROPISETRON;

EID: 44949237887     PISSN: 14622416     EISSN: 17448042     Source Type: Journal    
DOI: 10.2217/14622416.9.5.501     Document Type: Article
Times cited : (68)

References (32)
  • 2
    • 0029095767 scopus 로고
    • Molecular cloning of human 5-hydroxytryptamine3 receptor: Heterogeneity in distribution and function among species
    • Miyake A, Mochizuki S, Takemoto Y, Akuzawa S: Molecular cloning of human 5-hydroxytryptamine3 receptor: heterogeneity in distribution and function among species. Mol. Pharmacol. 48(3), 407-416 (1995).
    • (1995) Mol. Pharmacol , vol.48 , Issue.3 , pp. 407-416
    • Miyake, A.1    Mochizuki, S.2    Takemoto, Y.3    Akuzawa, S.4
  • 3
    • 34347253875 scopus 로고    scopus 로고
    • Characterization of the novel human serotonin receptor subunits 5-HT3C, 5-HT3D and 5-HT3E
    • Niesler B, Walstab J, Combrink S et al.: Characterization of the novel human serotonin receptor subunits 5-HT3C, 5-HT3D and 5-HT3E. Mol. Pharmacol. 72(1), 8-17 (2007).
    • (2007) Mol. Pharmacol , vol.72 , Issue.1 , pp. 8-17
    • Niesler, B.1    Walstab, J.2    Combrink, S.3
  • 4
    • 0037835606 scopus 로고    scopus 로고
    • Cloning, physical mapping and expression analysis of the human 5-HT3 serotonin receptor-like genes HTR3C, HTR3D and HTR3E
    • Niesler B, Frank B, Kapeller J, Rappold GA: Cloning, physical mapping and expression analysis of the human 5-HT3 serotonin receptor-like genes HTR3C, HTR3D and HTR3E. Gene 310, 101-111 (2003).
    • (2003) Gene , vol.310 , pp. 101-111
    • Niesler, B.1    Frank, B.2    Kapeller, J.3    Rappold, G.A.4
  • 5
    • 0033611396 scopus 로고    scopus 로고
    • The 5-HT3B subunit is a major determinant of serotonin-receptor function
    • Davies PA, Pistis M, Hanna, MC et al.: The 5-HT3B subunit is a major determinant of serotonin-receptor function. Nature 397(6717), 359-363 (1999).
    • (1999) Nature , vol.397 , Issue.6717 , pp. 359-363
    • Davies, P.A.1    Pistis, M.2    Hanna, M.C.3
  • 6
    • 0032697489 scopus 로고    scopus 로고
    • The pharmacological and functional characteristics of the serotonin 5-HT(3A) receptor are specifically modified by a 5-HT(3B) receptor subunit
    • Dubin AE, Huvar R, D'Andrea MR et al.: The pharmacological and functional characteristics of the serotonin 5-HT(3A) receptor are specifically modified by a 5-HT(3B) receptor subunit. J. Biol. Chem. 274(43), 30799-30810 (1999).
    • (1999) J. Biol. Chem , vol.274 , Issue.43 , pp. 30799-30810
    • Dubin, A.E.1    Huvar, R.2    D'Andrea, M.R.3
  • 7
    • 0034904107 scopus 로고    scopus 로고
    • Pharmacological comparison of human homomeric 5-HT3A receptors versus heteromeric 5-HT3A/3B receptors
    • Brady CA, Stanford IM, Ali I et al.: Pharmacological comparison of human homomeric 5-HT3A receptors versus heteromeric 5-HT3A/3B receptors. Neuropharmacology 41(2), 282-284 (2001).
    • (2001) Neuropharmacology , vol.41 , Issue.2 , pp. 282-284
    • Brady, C.A.1    Stanford, I.M.2    Ali, I.3
  • 8
    • 10744228499 scopus 로고    scopus 로고
    • A cluster of novel serotonin receptor 3-like genes on human chromosome 3
    • Karnovsky AM, Gotow LF, McKinley DD et al.: A cluster of novel serotonin receptor 3-like genes on human chromosome 3. Gene 319, 137-148 (2003).
    • (2003) Gene , vol.319 , pp. 137-148
    • Karnovsky, A.M.1    Gotow, L.F.2    McKinley, D.D.3
  • 9
    • 10644290207 scopus 로고    scopus 로고
    • Review article: Serotonin receptors and transporters - roles in normal and abnormal gastrointestinal motility
    • Gershon MD: Review article: serotonin receptors and transporters - roles in normal and abnormal gastrointestinal motility. Aliment. Pharmacol. Ther. 20(Suppl. 7) 3-14 (2004).
    • (2004) Aliment. Pharmacol. Ther , vol.20 , Issue.SUPPL. 7 , pp. 3-14
    • Gershon, M.D.1
  • 10
    • 33748922627 scopus 로고    scopus 로고
    • Serotonin 5-HT(3) receptors in the central nervous system
    • Chameau P, van Hooft JA: Serotonin 5-HT(3) receptors in the central nervous system. Cell Tissue Res. 326(2), 573-581 (2006).
    • (2006) Cell Tissue Res , vol.326 , Issue.2 , pp. 573-581
    • Chameau, P.1    van Hooft, J.A.2
  • 11
    • 0031596715 scopus 로고    scopus 로고
    • The central 5-HT3 receptor in CNS disorders
    • Bloom FE, Morales M: The central 5-HT3 receptor in CNS disorders. Neurochem. Res. 23(5), 653-659 (1998).
    • (1998) Neurochem. Res , vol.23 , Issue.5 , pp. 653-659
    • Bloom, F.E.1    Morales, M.2
  • 12
    • 33947677144 scopus 로고    scopus 로고
    • The 5-HT3 receptor as a therapeutic target
    • Thompson AJ, Lummis SC: The 5-HT3 receptor as a therapeutic target. Expert Opin. Ther. Targets 11 (4), 527-540 (2007).
    • (2007) Expert Opin. Ther. Targets , vol.11 , Issue.4 , pp. 527-540
    • Thompson, A.J.1    Lummis, S.C.2
  • 13
    • 0036460817 scopus 로고    scopus 로고
    • Ligand-gated ion channels in the enteric nervous system
    • Galligan JJ: Ligand-gated ion channels in the enteric nervous system. Neurogastroenterol. Motil. 14(6), 611-623 (2002).
    • (2002) Neurogastroenterol. Motil , vol.14 , Issue.6 , pp. 611-623
    • Galligan, J.J.1
  • 14
    • 25444432562 scopus 로고    scopus 로고
    • 5-HT(3)-receptor antagonists in the management of nausea and vomiting in cancer and cancer treatment
    • Aapro M: 5-HT(3)-receptor antagonists in the management of nausea and vomiting in cancer and cancer treatment. Oncology 69(2), 97-109 (2005).
    • (2005) Oncology , vol.69 , Issue.2 , pp. 97-109
    • Aapro, M.1
  • 15
    • 23244446441 scopus 로고    scopus 로고
    • Nerves, reflexes, and the enteric nervous system: Pathogenesis of the irritable bowel syndrome
    • Gershon MD: Nerves, reflexes, and the enteric nervous system: pathogenesis of the irritable bowel syndrome. J. Clin. Gastroenterol. 39(Suppl. 5), S184-S193 (2005).
    • (2005) J. Clin. Gastroenterol , vol.39 , Issue.SUPPL. 5
    • Gershon, M.D.1
  • 16
    • 33646870356 scopus 로고    scopus 로고
    • Review article: Intestinal serotonin signalling in irritable bowel syndrome
    • Mawe GM, Coates MD, Moses PL: Review article: intestinal serotonin signalling in irritable bowel syndrome. Aliment, Pharmacol. Ther. 23(8), 1067-1076 (2006).
    • (2006) Aliment, Pharmacol. Ther , vol.23 , Issue.8 , pp. 1067-1076
    • Mawe, G.M.1    Coates, M.D.2    Moses, P.L.3
  • 17
    • 17744374472 scopus 로고    scopus 로고
    • Serotonin receptor gene HTR3A variants in schizophrenic and bipolar affective patients
    • Niesler B, Weiss B, Fischer C et al.: Serotonin receptor gene HTR3A variants in schizophrenic and bipolar affective patients. Pharmacogenetics 11(1), 21-27 (2001).
    • (2001) Pharmacogenetics , vol.11 , Issue.1 , pp. 21-27
    • Niesler, B.1    Weiss, B.2    Fischer, C.3
  • 18
    • 33745698343 scopus 로고    scopus 로고
    • Distinguishable haplotype blocks in the HTR3A and HTR3B region in the Japanese reveal evidence of association of HTR3B with female major depression
    • Yamada K, Hattori E, Iwayama Y et al.: Distinguishable haplotype blocks in the HTR3A and HTR3B region in the Japanese reveal evidence of association of HTR3B with female major depression. Biol. Psychiat. 60(2), 192-201 (2006).
    • (2006) Biol. Psychiat , vol.60 , Issue.2 , pp. 192-201
    • Yamada, K.1    Hattori, E.2    Iwayama, Y.3
  • 19
    • 0034742439 scopus 로고    scopus 로고
    • Association between the 5' UTR variant C178T of the serotonin receptor gene HTR3A and bipolar affective disorder
    • Niesler B, Flohr T, Nöthen MM et al.: Association between the 5' UTR variant C178T of the serotonin receptor gene HTR3A and bipolar affective disorder. Pharmacogenetics 11(6), 471-475 (2001).
    • (2001) Pharmacogenetics , vol.11 , Issue.6 , pp. 471-475
    • Niesler, B.1    Flohr, T.2    Nöthen, M.M.3
  • 20
    • 10744223528 scopus 로고    scopus 로고
    • A polymorphism in the serotonin receptor 3A (HTR3A) gene and its association with harm avoidance in women
    • Melke J, Westberg L, Nilsson S et al.: A polymorphism in the serotonin receptor 3A (HTR3A) gene and its association with harm avoidance in women. Arch. Gen. Psychiat. 60(10), 1017-1023 (2003).
    • (2003) Arch. Gen. Psychiat , vol.60 , Issue.10 , pp. 1017-1023
    • Melke, J.1    Westberg, L.2    Nilsson, S.3
  • 21
    • 22044431993 scopus 로고    scopus 로고
    • A variant C178T in the regulatory region of the serotonin receptor gene HTR3A modulates neural activation in the human amygdala
    • Iidaka T, Ozaki N, Matsumoto A et al.: A variant C178T in the regulatory region of the serotonin receptor gene HTR3A modulates neural activation in the human amygdala. J. Neurosci. 25(27), 6460-6466 (2005).
    • (2005) J. Neurosci , vol.25 , Issue.27 , pp. 6460-6466
    • Iidaka, T.1    Ozaki, N.2    Matsumoto, A.3
  • 22
    • 33751298055 scopus 로고    scopus 로고
    • Do polymorphisms in the human 5-HT3genes contribute to pathological phenotypes?
    • Krzywkowski K: Do polymorphisms in the human 5-HT3genes contribute to pathological phenotypes? Biochem. Soc. Trans. 34(Pt 5), 872-876 (2006).
    • (2006) Biochem. Soc. Trans , vol.34 , Issue.PART 5 , pp. 872-876
    • Krzywkowski, K.1
  • 23
    • 34247598903 scopus 로고    scopus 로고
    • Naturally occurring variations in the human 5-HT3A gene profoundly impact 5-HT3 receptor function and expression
    • Thompson AJ, Sullivan NL, Lummis SC et al.: Naturally occurring variations in the human 5-HT3A gene profoundly impact 5-HT3 receptor function and expression. Pharmacogenet. Genomics 17(4), 255-266 (2007).
    • (2007) Pharmacogenet. Genomics , vol.17 , Issue.4 , pp. 255-266
    • Thompson, A.J.1    Sullivan, N.L.2    Lummis, S.C.3
  • 24
    • 34147136600 scopus 로고    scopus 로고
    • Characterization of 5-HT3 receptor mutations identified in schizophrenic patients
    • Thompson AJ, Sullivan NL, Lummis SC: Characterization of 5-HT3 receptor mutations identified in schizophrenic patients. J. Mol. Neurosci. 30(3), 273-281 (2006).
    • (2006) J. Mol. Neurosci , vol.30 , Issue.3 , pp. 273-281
    • Thompson, A.J.1    Sullivan, N.L.2    Lummis, S.C.3
  • 25
    • 1642378870 scopus 로고    scopus 로고
    • Pharmacological and electrophysiological properties of the naturally occurring Pro391Arg variant of the human 5-HT3A receptor
    • Kurzwelly D, Barann M, Kostanian A et al.: Pharmacological and electrophysiological properties of the naturally occurring Pro391Arg variant of the human 5-HT3A receptor. Pharmacogenetics 14(3), 165-172 (2004).
    • (2004) Pharmacogenetics , vol.14 , Issue.3 , pp. 165-172
    • Kurzwelly, D.1    Barann, M.2    Kostanian, A.3
  • 26
    • 7644223931 scopus 로고    scopus 로고
    • Investigation of the human serotonin receptor gene HTR3B in bipolar affective and schizophrenic patients
    • Frank B, Niesler B, Nöthen MM et al.: Investigation of the human serotonin receptor gene HTR3B in bipolar affective and schizophrenic patients. Am. J. Med. Genet. B Neuropsychiatr. Genet. 131(1), 1-5 (2004).
    • (2004) Am. J. Med. Genet. B Neuropsychiatr. Genet , vol.131 , Issue.1 , pp. 1-5
    • Frank, B.1    Niesler, B.2    Nöthen, M.M.3
  • 27
    • 38649128750 scopus 로고    scopus 로고
    • High-frequency HTR3B variant associated with major depression dramatically augments the signaling of the human 5-HT3AB receptor
    • Krzywkowski K, Davies PA, Feinberg-Zadek PL, Bräuner-Osborne H, Jensen AA: High-frequency HTR3B variant associated with major depression dramatically augments the signaling of the human 5-HT3AB receptor. Proc. Natl Acad. Sci. USA 105(2), 722-727 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , Issue.2 , pp. 722-727
    • Krzywkowski, K.1    Davies, P.A.2    Feinberg-Zadek, P.L.3    Bräuner-Osborne, H.4    Jensen, A.A.5
  • 28
    • 40049107733 scopus 로고    scopus 로고
    • Functional characterization of a-100-102delAAG deletion-insertion polymorphism in the promoter region of the HTR3B gene
    • Meineke C, Tzvetkov MV, Bokelmann K et al.: Functional characterization of a-100-102delAAG deletion-insertion polymorphism in the promoter region of the HTR3B gene. Pharmacogenet. Genomics 18(3), 219-230 (2008).
    • (2008) Pharmacogenet. Genomics , vol.18 , Issue.3 , pp. 219-230
    • Meineke, C.1    Tzvetkov, M.V.2    Bokelmann, K.3
  • 29
    • 2442543441 scopus 로고    scopus 로고
    • Investigation of the association between 5HHT3A receptor gene polymorphisms and efficiency of antiemetic treatment with 5-HT3 receptor antagonists
    • Kaiser R, Tremblay PB, Sezer O, Possinger K, Roots I, Brockmöller J: Investigation of the association between 5HHT3A receptor gene polymorphisms and efficiency of antiemetic treatment with 5-HT3 receptor antagonists. Pharmacogenetics 14(5), 271-278 (2004).
    • (2004) Pharmacogenetics , vol.14 , Issue.5 , pp. 271-278
    • Kaiser, R.1    Tremblay, P.B.2    Sezer, O.3    Possinger, K.4    Roots, I.5    Brockmöller, J.6
  • 30
    • 0037868158 scopus 로고    scopus 로고
    • Variations in the 5-hydroxytryptamine type 3B receptor gene as predictors of the efficacy of antiemetic treatment in cancer patients
    • Tremblay PB, Kaiser R, Sezer O et al.: Variations in the 5-hydroxytryptamine type 3B receptor gene as predictors of the efficacy of antiemetic treatment in cancer patients. J Clin. Oncol. 21(11), 2147-2155 (2003).
    • (2003) J Clin. Oncol , vol.21 , Issue.11 , pp. 2147-2155
    • Tremblay, P.B.1    Kaiser, R.2    Sezer, O.3
  • 31
    • 33749252329 scopus 로고    scopus 로고
    • The effect of 5-hydroxytryptamine 3A and 3B receptor genes on nausea induced by paroxetine
    • Sugai T, Suzuki Y, Sawamura K, Fukui N, Inoue Y, Someya T: The effect of 5-hydroxytryptamine 3A and 3B receptor genes on nausea induced by paroxetine. Pharmacogenomics J. 6(5), 351-356 (2006).
    • (2006) Pharmacogenomics J , vol.6 , Issue.5 , pp. 351-356
    • Sugai, T.1    Suzuki, Y.2    Sawamura, K.3    Fukui, N.4    Inoue, Y.5    Someya, T.6
  • 32
    • 33747396949 scopus 로고    scopus 로고
    • Effects of the serotonin type 2A, 3A and 3B receptor and the serotonin transporter genes on paroxetine and fluvoxamine efficacy and adverse drug reactions in depressed Japanese patients
    • Kato M, Fukuda T, Wakeno M et al.: Effects of the serotonin type 2A, 3A and 3B receptor and the serotonin transporter genes on paroxetine and fluvoxamine efficacy and adverse drug reactions in depressed Japanese patients. Neuropsychobiology 53(4), 186-195 (2006).
    • (2006) Neuropsychobiology , vol.53 , Issue.4 , pp. 186-195
    • Kato, M.1    Fukuda, T.2    Wakeno, M.3


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