Scintigraphic assessment of regionalized defects in myocardial sympathetic innervation and blood flow regulation in diabetic patients with autonomic neuropathy

Journal of the American College of Cardiology

Volumn 31, Issue 7, 1998, Pages 1575-1584

  Stevens, Martin J ^a   Dayanikli, Firat ^a   Raffel, David M ^a   Allman, Kevin C ^a   Sandford, Tracy ^a   Feldman, Eva L ^a   Wieland, Donald M ^a   Corbett, James ^a   Schwaiger, Marcus ^a  

^a Division of Metabolism Endocrinology and Diabetes   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; AMMONIA; CARBON 11; EPHEDRINE; NITROGEN 13;

ADULT; ARTICLE; AUTONOMIC NEUROPATHY; CLINICAL ARTICLE; CONTROLLED STUDY; DIABETIC NEUROPATHY; FEMALE; HEART DENERVATION; HEART MUSCLE BLOOD FLOW; HEART SCINTISCANNING; HUMAN; IMAGE ANALYSIS; MALE; PRIORITY JOURNAL; SUDDEN DEATH; SYMPATHETIC INNERVATION;

ADENOSINE; ADULT; ANALYSIS OF VARIANCE; CARBON RADIOISOTOPES; CORONARY CIRCULATION; DIABETIC NEUROPATHIES; FEMALE; HEART; HUMANS; MALE; MIDDLE AGED; REGIONAL BLOOD FLOW; SYMPATHETIC NERVOUS SYSTEM; TOMOGRAPHY, EMISSION-COMPUTED; VASODILATOR AGENTS;

EID: 0031800724     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0735-1097(98)00128-4     Document Type: Article

References (64)

1. Hilsted J., Jeensen S.B. A simple test for autonomic neuropathy in juvenile diabetics. Acta Med Scand. 205:1979;385-387.
2. Dryberg T., Benn J., Christiansen J., Hilsted J., Nerup J. Prevalence of diabetic autonomic neuropathy measured by simple bedside tests. Diabetologia. 20:1981;190-194.
3. O'Brien O.A., McFadden J.P., Corrall R.J.M. The influence of autonomic neuropathy on mortality in insulin-dependent diabetes. Q J Med. 290:1991;495-502.
4. Navarro X., Kennedy W.R., Sutherland D.E.R. Autonomic neuropathy and survival in diabetes mellitus effects of pancreas transplantation . Diabetologia. 34:(Suppl 1):1991;S108-S112.
5. Rathman W., Ziegler D., Jahnke M., Haastert B., Gries F.A. Mortality in diabetic patients with cardiovascular autonomic neuropathy. Diabetic Med. 10:1993;820-824.
6. Sampson M.J., Wilson S., Karagiannis P., Edmonds M.E., Watkins P.J. Progression of diabetic autonomic neuropathy over a decade in insulin-dependent diabetics. Q J Med. 75:1990;635-646.
7. Ewing D.J., Campbell I.W., Clarke B.F. The natural history of diabetic autonomic neuropathy. Q J Med. 49:1980;95-108.
8. Ewing D.J., Campbell I.W., Clarke B.F. Mortality in diabetic autonomic neuropathy. Lancet. 1:1976;601-603.
9. Page M.M., Watkins P.J. The heart in diabetes autonomic neuropathy and cardiomyopathy . Clin Endocrinol Metab. 6:1977;377-388.
10. Shapiro L.M. Echocardiographic features of impaired ventricular function in diabetes mellitus. Br Heart J. 47:1982;439-444.
11. Fisher B.M., Gillen G., Lindop G.B.M., Dargie H.J., Frier B.M. Cardiac function and coronary arteriography in asymptomatic type 1 (insulin-dependent) diabetic patients evidence for a specific diabetic heart disease . Diabetologia. 29:1986;706-712.
12. Langer A., Freeman M.E., Josse R.G., Armstrong P.W. Metaiodobenzylguanidine imaging in diabetes mellitus assessment of cardiac sympathetic denervation and its relation to autonomic dysfunction and silent myocardial ischemia . J Am Coll Cardiol. 25:1995;610-618.
13. Zola B., Kahn J.K., Juni J.E., Vinik A.I. Abnormal cardiac function in diabetic patients with autonomic neuropathy in the absence of ischemic heart disease. J Clin Endocrinol Metab. 63:1986;208-214.
14. Rubler S., Reicher-Reiss H., Pulini M. Diabetes mellitus and impaired atrioventricular conduction. NY State J Med. 75:1975;2517-2521.
15. Hasslacher C., Wahl P. Diabetes prevalence in patients with bradycardiac arrhythmias. Acta Diabetol Lat. 14:1977;229-234.
16. Willich S.N., Maclure M., Mittleman M., Arntz H.-R., Muller J.E. Sudden cardiac death support for the role of triggering in causation . Circulation. 87:1993;1442-1450.
17. Lown B., Verrier R.L. Neural activity and ventricular fibrillation. N Engl J Med. 294:1976;1165-1170.
18. Schwartz P.J., Motolese M., Pollavini G., et al. Prevention of sudden cardiac death after a first myocardial infarction by pharmacologic or surgical antiadrenergic interventions. J Cardiovasc Electrophysiol. 3:1992;2-16.
19. Holtz J., Mayer E., Bassenge E. Demonstration of α-adrenergic coronary control in different layers of canine myocardium by regional myocardial sympathectomy. Pflugers Arch. 372:1977;187-194.
20. Griggs D.M. Jr, Chilian W.M., Boatwright R.B., Shoji T., Williams D.O. Evidence against significant resting α-adrenergic coronary vasoconstrictor tone. Fed Proc. 43:1984;2873-2877.
21. Hjalmarson A., Elmfeldt D., Herlitz J., et al. Effect on mortality of metoprolol in acute myocardial infarction, a double-blind randomized trial. Lancet. 2:1981;123-127.
22. Timolol-induced reduction in mortality and reinfarction in patients surviving acute myocardial infarction. N Engl J Med. 304:1981;801-807.
23. The effect of pindolol on the two year mortality after complicated myocardial infarction. Eur Heart J. 4:1983;367-375.
24. Fava S., Azzopardi J., Muscatt H.A., Fenech F.F. Factors that influence outcome in diabetic subjects with myocardial infarction. Diabetes Care. 16:1993;1615-1618.
25. Mohrman D.E., Feigl E.O. Competition between sympathetic vasoconstriction and metabolic vasodilation in the canine coronary circulation. Circ Res. 42:1978;79-86.
26. DeWitt D.F., Wangler R.D., Thompson C.I., Sparks H.V. Phasic release of adenosine during steady state metabolic stimulation in the isolated guinea pig heart. Circ Res. 53:1983;636-643.
27. Roth D.M., Reibel D.K., Lefer A.M. Vascular responsiveness and eicosanoids in diabetic rats. Diabetologia. 24:1983;372-376.
28. Koltai M., Jermendy G., Kiss V., Wagner M., Pogatsa G. The effects of sympathetic nerve stimulation and adenosine on coronary circulation and heart function in diabetes mellitus. Acta Physiol Hung. 63:1984;119-125.
29. Nabel E.G., Ganz P., Gordon J.B., Alexander R., Selwyn A.P. Dilation of normal and constriction of atherosclerotic coronary arteries caused by the cold pressor test. Circulation. 77:1988;43-52.
30. Allman K.C., Stevens M.J., Wieland D.M., et al. Noninvasive assessment of cardiac diabetic neuropathy by C-11 hydroxyephedrine and positron emission tomography. J Am Coll Cardiol. 22:1993;1425-1432.
31. Saenz de Tejada I., Goldstein I., Azadzoi K., Krane R.J., Cohen R.A. Impaired neurogenic and endothelium-mediated relaxation of the penile smooth muscle from diabetic men with impotence. N Engl J Med. 320:1989;1025-1030.
32. Moncada S., Palmer R.M.J., Higgs E.A. Nitric oxide physiology, pathophysiology and pharmacology . Pharmacol Rev. 43:1991;109-141.
33. Harrison H.E., Reece A.H., Johnson M. Decreased vascular prostacyclin in experimental diabetes. Life Sci. 23:1978;354-356.
34. Takahashi K., Ghatei M.A., Lam H.C., O'Halloran D.J., Bloom S.R. Elevated plasma endothelin in patients with diabetes mellitus. Diabetologia. 33:1990;306-310.
35. DeGrado T.R., Hutchins G.D., Toorongian S.A., Wieland D.M., Schwaiger M. Myocardial kinetics of carbon-11-meta-hydroxyephedrine (HED) retention mechanisms and effects of norepinephrine . J Nucl Med. 34:1993;1287-1293.
36. Rosenspire K.C., Haka M.S., Van Dort M.E., et al. Synthesis and preliminary evaluation of [c-11] meta-hydroxyephedrine, a false transmitter agent for heart neuronal imaging. J Nucl Med. 31:1990;1328-1334.
37. Rembert J.C., Boyd L.M., Watkinson W.P., Greenfield J.C. Effect of adenosine on transmural myocardial blood flow distribution in the awake dog. Am J Physiol. 239:1980;H7-H13.
38. Hutchins G.D., Schwaiger M., Rosenspire K.C., Krivokapich J., Schelbert H., Kuhl D.E. Noninvasive quantitation of regional blood flow in the human heart using N-13 ammonia and dynamic positron emission tomographic imaging. J Am Coll Cardiol. 15:1990;1032-1042.
39. Ewing D.J., Clarke B.F. Diagnosis and management of diabetic autonomic neuropathy. BMJ. 285:1982;916-918.
40. Wheeler T., Watkins P.J. Cardiac denervation in diabetes. BMJ. 4:1973;584-586.
41. Genovely H., Pfeifer M.A. RR-variation the autonomic test of choice in diabetes . Diabetes Metab Rev. 4:1988;255-271.
42. Knezevic N., Bajada S. Peripheral autonomic surface potential a quantitative technique for recording sympathetic conduction in man . J Neurol Sci. 67:1985;239-251.
43. Schwaiger M., Musik O. Assessment of myocardial perfusion by positron emission tomography. Am J Cardiol. 67:1991;35D-43D.
44. Bergman S., Herrero P., Markham J., Weinheimer C., Walsh M. Noninvasive quantification of myocardial blood flow in human subjects with oxygen-15-labeled water and positron emission tomography. J Am Coll Cardiol. 14:1989;639-652.
45. Wilson R.F., Wyche K., Christensen B.V., Zimmer S., Laxson D.D. Effects of adenosine on human coronary arterial circulation. Circulation. 82:1990;1595-1606.
46. Nitenberg A., Valensi P., Sachs R., Dali M., Aptecar E., Attali J.-R. Impairment of coronary vascular reserve and ACH-induced coronary vasodilatation in diabetic patients with angiographically normal coronary arteries and normal left ventricular systolic function. Diabetes. 42:1993;1017-1025.
47. Gollwitzer-Meier K., Kruger E. Einfluss der Herznerven auf den Gaswechsel des Warmbluterherzens. Pfluegers Arch. 240:1938;89-110.
48. 2 consumption after sympathetic nerve stimulation. Am J Physiol. 163:1950;539-544.
49. Jones C.E., Scheel K.W. Reduced coronary collateral resistances after chronic ventricular sympathectomy. Am J Physiol. 238:1980;H196-H201.
50. Jones C.E., Liang I.Y.S., Mass H.J., Gwirtz P.A. Response to brief coronary stenosis in conscious dogs after ventricular sympathectomy. Am J Physiol. 252:1987;H923-H932.
51. Tomanek R.J. Sympathetic nerves modify mitochondrial and capillary growth in normotensive and hypertensive rats. J Mol Cell Cardiol. 21:1989;755-764.
52. Torry R.J., Connell P.M., O'Brien D.M., Chilian W.M., Tomanek R.J. Sympathectomy stimulates capillary but not precapillary growth in hypertrophic hearts. Am J Physiol. 260:1991;H1515-H1521.
53. Acad B.-A., Weiss H.R. Chemical sympathectomy and utilization of coronary capillary reserve in rabbits. Microvasc Res. 36:1988;250-261.
54. Levy M.N., Zieske H. Comparison of the effects of vagus nerve stimulation and of acetylcholine infusions. Am J Physiol. 216:1969;890-897.
55. Sutherland C.G.G., Fisher B.M., Firer B.M., et al. Endomyocardial biopsy pathology in insulin-dependent diabetic patients with abnormal ventricular function. Histopathology. 14:1989;593-602.
56. Zoneraich S., Silverman G., Zoneraich O. Primary myocardial disease, diabetes mellitus, and small vessel disease. Am Heart J. 100:1980;754-755.
57. Wilhelmsson C., Vedin J.A., Wilhelmsen L., Tibblin G., Werko L. Reduction of sudden death after myocardial infarction by treatment with alprenolol preliminary results . Lancet. 2:1974;1157-1160.
58. Kleiger RE, Miller JP, Bigger JT, Moss AJ, for the Multicenter Post-Infarction Research Group. Decreased heart rate variability and its association with increased mortality after acute myocardial infarction. Am J Cardiol 1987;59:256-62.
59. Yusuf S., Peto R., Lewis J., Collins R., Sleight P. Beta blockade during and after myocardial infarction an overview of the randomized trials . Prog Cardiovasc Dis. 27:1985;335-371.
60. Murata K., Sumida Y., Murashima S., et al. A novel method for the assessment of autonomic neuropathy in type 2 diabetic patients a comparative evaluation of 123I-MIBG myocardial scintigraphy and power spectral analysis of heart rate variability . Diabet Med. 13:1996;266-272.
61. Turpeinen A.K., Vanninen E., Kuikka J.T., Uusitupa M.I.J. Demonstration of regional sympathetic denervation of the heart in diabetes. Diabetes Care. 19:1996;1083-1090.
62. Shimabukuro M., Chibana T., Yoshida H., Nagamine F., Komiya I., Takasu N. Increased QT dispersion and cardiac adrenergic dysinnervation in diabetic patients with autonomic neuropathy. Am J Cardiol. 78:1996;1057-1059.
63. Algra A., Tijssen J.G.P., Roelandt J.R.T.C., Pool J., Lubsen J. Heart rate variability from 24-hour electrocardiography and the 2-year risk for sudden death. Circulation. 88:1993;180-185.
64. Schwartz P.J., Randall W.C., Anderson E.A., et al. Task Force 4. Sudden cardiac death: nonpharmacologic interventions. Circulation. 76:1987;I215-I219.