-
1
-
-
29244459436
-
The substituted (S)-3-phenylpiperidine (-)-OSU6162 reduces apomorphine- and amphetamine-induced behaviour in Cebus apella monkeys
-
1
-
Brandt-Christensen M, Andersen MB, Fink-Jensen A, Werge T, Gerlach J (2006) The substituted (S)-3-phenylpiperidine (-)-OSU6162 reduces apomorphine- and amphetamine-induced behaviour in Cebus apella monkeys. J Neural Transm 113(1):11-19
-
(2006)
J Neural Transm
, vol.113
, pp. 11-19
-
-
Brandt-Christensen, M.1
Andersen, M.B.2
Fink-Jensen, A.3
Werge, T.4
Gerlach, J.5
-
2
-
-
33645887346
-
Pharmacokinetics and pharmacodynamics: The dynamics of drug absorption, distribution, action, and elimination
-
11 McGraw-Hill New York
-
Buxton ILO (2005) Pharmacokinetics and pharmacodynamics: the dynamics of drug absorption, distribution, action, and elimination. In: Brunton LL, Lazo JS, Parker KL (eds) Goodman & Gilman's the pharmacological basis of therapeutics, 11th edn. McGraw-Hill, New York
-
(2005)
Goodman & Gilman's the Pharmacological Basis of Therapeutics
-
-
Buxton, I.L.O.1
Brunton, L.L.2
Lazo, J.S.3
Parker, K.L.4
-
3
-
-
0021043048
-
Dopamine receptor agonists: Intrinsic activity vs. state of receptor
-
4
-
Carlsson A (1983) Dopamine receptor agonists: intrinsic activity vs. state of receptor. J Neural Transm 57(4):309-315
-
(1983)
J Neural Transm
, vol.57
, pp. 309-315
-
-
Carlsson, A.1
-
4
-
-
0035800896
-
A half-century of neurotransmitter research: Impact on neurology and psychiatry (Nobel lecture)
-
7-8
-
Carlsson A (2001) A half-century of neurotransmitter research: impact on neurology and psychiatry (Nobel lecture). Chembiochem 2(7-8):484-493
-
(2001)
Chembiochem
, vol.2
, pp. 484-493
-
-
Carlsson, A.1
-
5
-
-
1242329383
-
Schizophrenia: From dopamine to glutamate and back
-
3
-
Carlsson ML, Carlsson A, Nilsson M (2004) Schizophrenia: from dopamine to glutamate and back. Curr Med Chem 11(3):267-277
-
(2004)
Curr Med Chem
, vol.11
, pp. 267-277
-
-
Carlsson, M.L.1
Carlsson, A.2
Nilsson, M.3
-
7
-
-
0002882514
-
(-)-OSU6162 induces a rapid onset of antipsychotic effect after a single dose. a double-blind placebo-controlled pilot study. Scandinavian Society for Psychopharmacology, 41st annual meeting, Copenhagen, Denmark
-
Gefvert O, Lindström LH, Dahlbäck O, Sonesson C, Waters N, Carlsson A, Tedroff J (2000) (-)-OSU6162 induces a rapid onset of antipsychotic effect after a single dose. A double-blind placebo-controlled pilot study. Scandinavian Society for Psychopharmacology, 41st annual meeting, Copenhagen, Denmark. Nord J Psychiat 54:93-94
-
(2000)
Nord J Psychiat
, vol.54
, pp. 93-94
-
-
Gefvert, O.1
Lindström, L.H.2
Dahlbäck, O.3
Sonesson, C.4
Waters, N.5
Carlsson, A.6
Tedroff, J.7
-
8
-
-
84946031884
-
Procedures for detecting outlying observations in samples
-
1
-
Grubbs FE (1969) Procedures for detecting outlying observations in samples. Technometrics 11(1):1-21
-
(1969)
Technometrics
, vol.11
, pp. 1-21
-
-
Grubbs, F.E.1
-
9
-
-
0242550580
-
How does the benzamide antipsychotic amisulpride get into the brain?-an in vitro approach comparing amisulpride with clozapine
-
11
-
Härtter S, Hüwel S, Lohmann T, Abou El Ela A, Langguth P, Hiemke C, Galla HJ (2003) How does the benzamide antipsychotic amisulpride get into the brain?-an in vitro approach comparing amisulpride with clozapine. Neuropsychopharmacology 28(11):1916-1922
-
(2003)
Neuropsychopharmacology
, vol.28
, pp. 1916-1922
-
-
Härtter, S.1
Hüwel, S.2
Lohmann, T.3
Abou El Ela, A.4
Langguth, P.5
Hiemke, C.6
Galla, H.J.7
-
10
-
-
0347057804
-
Aripiprazole is a potent, partial agonist at cloned human D2L and native rat 5-HT1A receptors
-
Suppl 3
-
Jordan S, Chen R, Johnson J, Regardie K, Tadori Y, Kikuchi T (2002a) Aripiprazole is a potent, partial agonist at cloned human D2L and native rat 5-HT1A receptors. Eur Neuropsychopharmacol 12(Suppl 3):293-294
-
(2002)
Eur Neuropsychopharmacol
, vol.12
, pp. 293-294
-
-
Jordan, S.1
Chen, R.2
Johnson, J.3
Regardie, K.4
Tadori, Y.5
Kikuchi, T.6
-
11
-
-
0037177358
-
The antipsychotic aripiprazole is a potent, partial agonist at the human 5-HT1A receptor
-
3
-
Jordan S, Koprivica V, Chen R, Tottori K, Kikuchi T, Altar CA (2002b) The antipsychotic aripiprazole is a potent, partial agonist at the human 5-HT1A receptor. Eur J Pharmacol 441(3):137-140
-
(2002)
Eur J Pharmacol
, vol.441
, pp. 137-140
-
-
Jordan, S.1
Koprivica, V.2
Chen, R.3
Tottori, K.4
Kikuchi, T.5
Altar, C.A.6
-
12
-
-
33846821695
-
Dopamine D2 receptor partial agonists display differential or contrasting characteristics in membrane and cell-based assays of dopamine D2 receptor signaling
-
2
-
Jordan S, Johnson JL, Regardie K, Chen R, Koprivica V, Tadori Y, Kambayashi J, Kitagawa H, Kikuchi T (2007a) Dopamine D2 receptor partial agonists display differential or contrasting characteristics in membrane and cell-based assays of dopamine D2 receptor signaling. Prog Neuropsychopharmacol Biol Psychiatry 31(2):348-356
-
(2007)
Prog Neuropsychopharmacol Biol Psychiatry
, vol.31
, pp. 348-356
-
-
Jordan, S.1
Johnson, J.L.2
Regardie, K.3
Chen, R.4
Koprivica, V.5
Tadori, Y.6
Kambayashi, J.7
Kitagawa, H.8
Kikuchi, T.9
-
13
-
-
34748829113
-
In vitro functional characteristics of dopamine D2 receptor partial agonists in second and third messenger-based assays of cloned human dopamine D2Long receptor signalling
-
6
-
Jordan S, Regardie K, Johnson JL, Chen R, Kambayashi J, McQuade R, Kitagawa H, Tadori Y, Kikuchi T (2007b) In vitro functional characteristics of dopamine D2 receptor partial agonists in second and third messenger-based assays of cloned human dopamine D2Long receptor signalling. J Psychopharmacol 21(6):620-627
-
(2007)
J Psychopharmacol
, vol.21
, pp. 620-627
-
-
Jordan, S.1
Regardie, K.2
Johnson, J.L.3
Chen, R.4
Kambayashi, J.5
McQuade, R.6
Kitagawa, H.7
Tadori, Y.8
Kikuchi, T.9
-
14
-
-
34548181763
-
Stimulating and inhibitory effects of the dopamine "stabilizer" (-)-OSU6162 on dopamine D(2) receptor function in vitro
-
9
-
Lahti RA, Tamminga CA, Carlsson A (2007) Stimulating and inhibitory effects of the dopamine "stabilizer" (-)-OSU6162 on dopamine D(2) receptor function in vitro. J Neural Transm 114(9):1143-1146
-
(2007)
J Neural Transm
, vol.114
, pp. 1143-1146
-
-
Lahti, R.A.1
Tamminga, C.A.2
Carlsson, A.3
-
15
-
-
44949203684
-
Safety of early clinical experience with (-)-OSU6162, a dopaminergic stabilizer with antipsychotic properties. In: SCNP 43rd Annual and 2nd Mediterranean Meeting, Juan-les-Pins, France
-
Lundberg T, Tedroff J, Waters N, Sonesson C, Carlsson A, Hagström P, Lindström LH, Gefvert O (2002) Safety of early clinical experience with (-)-OSU6162, a dopaminergic stabilizer with antipsychotic properties. In: SCNP 43rd Annual and 2nd Mediterranean Meeting, Juan-les-Pins, France. Nord J Psychiatry 56:24
-
(2002)
Nord J Psychiatry
, vol.56
, pp. 24
-
-
Lundberg, T.1
Tedroff, J.2
Waters, N.3
Sonesson, C.4
Carlsson, A.5
Hagström, P.6
Lindström, L.H.7
Gefvert, O.8
-
16
-
-
0031969706
-
Agonist and inverse agonist activity at the dopamine D3 receptor measured by guanosine 5'-[-Thio]triphosphate-[35S] binding
-
1
-
Malmberg Å, Mikaels Å, Mohell N (1998) Agonist and inverse agonist activity at the dopamine D3 receptor measured by guanosine 5'-[-Thio]triphosphate-[35S] binding. J Pharmacol Exp Ther 285(1):119-126
-
(1998)
J Pharmacol Exp Ther
, vol.285
, pp. 119-126
-
-
Malmberg A.̊1
Mikaels A.̊2
Mohell, N.3
-
17
-
-
33745933839
-
The dopamine stabilizers (S)-(-)-(3-methanesulfonyl-phenyl)-1-propyl- piperidine [(-)-OSU6162] and 4-(3-methanesulfonylphenyl)-1-propyl-piperidine (ACR16) show high in vivo D2 receptor occupancy, antipsychotic-like efficacy, and low potential for motor side effects in the rat
-
2
-
Natesan S, Svensson KA, Reckless GE, Nobrega JN, Barlow KB, Johansson AM, Kapur S (2006) The dopamine stabilizers (S)-(-)-(3-methanesulfonyl-phenyl)-1- propyl-piperidine [(-)-OSU6162] and 4-(3-methanesulfonylphenyl)-1-propyl- piperidine (ACR16) show high in vivo D2 receptor occupancy, antipsychotic-like efficacy, and low potential for motor side effects in the rat. J Pharmacol Exp Ther 318(2):810-818
-
(2006)
J Pharmacol Exp Ther
, vol.318
, pp. 810-818
-
-
Natesan, S.1
Svensson, K.A.2
Reckless, G.E.3
Nobrega, J.N.4
Barlow, K.B.5
Johansson, A.M.6
Kapur, S.7
-
18
-
-
0030933627
-
Psychopharmacological profile of amisulpride: An antipsychotic drug with presynaptic D2/D3 dopamine receptor antagonist activity and limbic selectivity
-
1
-
Perrault G, Depoortere R, Morel E, Sanger DJ, Scatton B (1997) Psychopharmacological profile of amisulpride: an antipsychotic drug with presynaptic D2/D3 dopamine receptor antagonist activity and limbic selectivity. J Pharmacol Exp Ther 280(1):73-82
-
(1997)
J Pharmacol Exp Ther
, vol.280
, pp. 73-82
-
-
Perrault, G.1
Depoortere, R.2
Morel, E.3
Sanger, D.J.4
Scatton, B.5
-
19
-
-
44949118667
-
Dopamine stabilizer ACR16 prevents L-DOPA induced sensitization in the 6-OHDA-lesioned rat
-
Orlando. Soc Neurosci Program No. 787.6
-
Pontén H, Carlsson A, Kullingsjö J, Sonesson C, Waters ES, Waters N, Tedroff J (2002) The dopamine stabilizer ACR16 prevents L-DOPA induced sensitization in the 6-OHDA-lesioned rat. In: 32nd annual meeting, society for neuroscience, Orlando. Soc Neurosci Program No. 787.6
-
(2002)
32nd Annual Meeting, Society for Neuroscience
-
-
Pontén, H.1
Carlsson, A.2
Kullingsjö, J.3
Sonesson, C.4
Waters, E.S.5
Waters, N.6
Tedroff, J.7
-
20
-
-
0031951428
-
Real-time assessments of dopamine function during behavior: Single-unit recording, iontophoresis, and fast-scan cyclic voltammetry in awake, unrestrained rats
-
1
-
Rebec GV (1998) Real-time assessments of dopamine function during behavior: single-unit recording, iontophoresis, and fast-scan cyclic voltammetry in awake, unrestrained rats. Alcohol Clin Exp Res 22(1):32-40
-
(1998)
Alcohol Clin Exp Res
, vol.22
, pp. 32-40
-
-
Rebec, G.V.1
-
23
-
-
8244235137
-
Neurochemical characteristics of amisulpride, an atypical dopamine D2/D3 receptor antagonist with both presynaptic and limbic selectivity.
-
1
-
Schoemaker H, Claustre Y, Fage D, Rouquier L, Chergui K, Curet O, Oblin A, Gonon F, Carter C, Benavides J, Scatton B (1997) Neurochemical characteristics of amisulpride, an atypical dopamine D2/D3 receptor antagonist with both presynaptic and limbic selectivity. J Pharmacol Exp Ther 280(1):83-97
-
(1997)
J Pharmacol Exp Ther
, vol.280
, pp. 83-97
-
-
Schoemaker, H.1
Claustre, Y.2
Fage, D.3
Rouquier, L.4
Chergui, K.5
Curet, O.6
Oblin, A.7
Gonon, F.8
Carter, C.9
Benavides, J.10
Scatton, B.11
-
24
-
-
33846702551
-
Dopamine partial agonist action of (-)OSU6162 is consistent with dopamine hyperactivity in psychosis
-
2-3
-
Seeman P, Guan HC (2007) Dopamine partial agonist action of (-)OSU6162 is consistent with dopamine hyperactivity in psychosis. Eur J Pharmacol 557(2-3):151-153
-
(2007)
Eur J Pharmacol
, vol.557
, pp. 151-153
-
-
Seeman, P.1
Guan, H.C.2
-
26
-
-
0344945101
-
The dopamine D3 receptor in the pathophysiology and treatment of neuropsychiatric disorders
-
2 Marcel Dekker New York
-
Sokoloff P, Griffon N, Gullin O, Diaz J, Pilon C, Schwartz J-C (2003) The dopamine D3 receptor in the pathophysiology and treatment of neuropsychiatric disorders. In: Sidhu A, Laruelle M, Vernier P (eds) Dopamine receptors and transporters, 2nd edn. Marcel Dekker, New York
-
(2003)
Dopamine Receptors and Transporters
-
-
Sokoloff, P.1
Griffon, N.2
Gullin, O.3
Diaz, J.4
Pilon, C.5
Schwartz, J.-C.6
Sidhu, A.7
Laruelle, M.8
Vernier, P.9
-
27
-
-
0027934781
-
Substituted (S)-phenylpiperidines and rigid congeners as preferential dopamine autoreceptor antagonists: Synthesis and structure-activity relationships
-
17
-
Sonesson C, Lin CH, Hansson L, Waters N, Svensson K, Carlsson A, Smith MW, Wikström H (1994) Substituted (S)-phenylpiperidines and rigid congeners as preferential dopamine autoreceptor antagonists: synthesis and structure-activity relationships. J Med Chem 37(17):2735-2753
-
(1994)
J Med Chem
, vol.37
, pp. 2735-2753
-
-
Sonesson, C.1
Lin, C.H.2
Hansson, L.3
Waters, N.4
Svensson, K.5
Carlsson, A.6
Smith, M.W.7
Wikström, H.8
-
28
-
-
0022461560
-
Effects of neuroleptic drugs on the inhibition of exploratory behaviour induced by a low dose of apomorphine: Implications for the identity of dopamine receptors
-
2
-
Ståhle L, Ungerstedt U (1986) Effects of neuroleptic drugs on the inhibition of exploratory behaviour induced by a low dose of apomorphine: implications for the identity of dopamine receptors. Pharmacol Biochem Behav 25(2):473-480
-
(1986)
Pharmacol Biochem Behav
, vol.25
, pp. 473-480
-
-
Ståhle, L.1
Ungerstedt, U.2
-
30
-
-
20344400385
-
Aripiprazole's low intrinsic activities at human dopamine D2L and D2S receptors render it a unique antipsychotic
-
1-3
-
Tadori Y, Miwa T, Tottori K, Burris KD, Stark A, Mori T, Kikuchi T (2005) Aripiprazole's low intrinsic activities at human dopamine D2L and D2S receptors render it a unique antipsychotic. Eur J Pharmacol 515(1-3):10-19
-
(2005)
Eur J Pharmacol
, vol.515
, pp. 10-19
-
-
Tadori, Y.1
Miwa, T.2
Tottori, K.3
Burris, K.D.4
Stark, A.5
Mori, T.6
Kikuchi, T.7
-
31
-
-
35348854954
-
Differences in agonist/antagonist properties at human dopamine D(2) receptors between aripiprazole, bifeprunox and SDZ 208-912
-
2-3
-
Tadori Y, Kitagawa H, Forbes RA, McQuade RD, Stark A, Kikuchi T (2007) Differences in agonist/antagonist properties at human dopamine D(2) receptors between aripiprazole, bifeprunox and SDZ 208-912. Eur J Pharmacol 574(2-3):103-111
-
(2007)
Eur J Pharmacol
, vol.574
, pp. 103-111
-
-
Tadori, Y.1
Kitagawa, H.2
Forbes, R.A.3
McQuade, R.D.4
Stark, A.5
Kikuchi, T.6
-
32
-
-
0032693984
-
Long-lasting improvement following (-)-OSU6162 in a patient with Huntington's disease
-
7
-
Tedroff J, Ekesbo A, Sonesson C, Waters N, Carlsson A (1999) Long-lasting improvement following (-)-OSU6162 in a patient with Huntington's disease. Neurology 53(7):1605-1606
-
(1999)
Neurology
, vol.53
, pp. 1605-1606
-
-
Tedroff, J.1
Ekesbo, A.2
Sonesson, C.3
Waters, N.4
Carlsson, A.5
-
33
-
-
0027521571
-
The dopamine D3-receptor: A postsynaptic receptor inhibitory on rat locomotor activity
-
1
-
Waters N, Svensson K, Haadsma Svensson SR, Smith MW, Carlsson A (1993) The dopamine D3-receptor: a postsynaptic receptor inhibitory on rat locomotor activity. J Neural Transm Gen Sect 94(1):11-19
-
(1993)
J Neural Transm Gen Sect
, vol.94
, pp. 11-19
-
-
Waters, N.1
Svensson, K.2
Haadsma Svensson, S.R.3
Smith, M.W.4
Carlsson, A.5
-
34
-
-
0028173014
-
Differential effects of dopamine D2 and D3 receptor antagonists in regard to dopamine release, in vivo receptor displacement and behaviour
-
1
-
Waters N, Löfberg L, Haadsma Svensson S, Svensson K, Sonesson C, Carlsson A (1994) Differential effects of dopamine D2 and D3 receptor antagonists in regard to dopamine release, in vivo receptor displacement and behaviour. J Neural Transm Gen Sect 98(1):39-55
-
(1994)
J Neural Transm Gen Sect
, vol.98
, pp. 39-55
-
-
Waters, N.1
Löfberg, L.2
Haadsma Svensson, S.3
Svensson, K.4
Sonesson, C.5
Carlsson, A.6
-
35
-
-
21244464168
-
Pharmacology of ACR16, a dopamine stabilizer
-
Orlando. Soc Neurosci Program No. 894.13
-
Waters N, Carlsson A, Carlsson M, Martin P, Tedroff J, Kullingsjö J, Pettersson F, Sonesson C, Waters ES (2002) Pharmacology of ACR16, a dopamine stabilizer. In: 32nd annual meeting, society for neuroscience, Orlando. Soc Neurosci Program No. 894.13
-
(2002)
32nd Annual Meeting, Society for Neuroscience
-
-
Waters, N.1
Carlsson, A.2
Carlsson, M.3
Martin, P.4
Tedroff, J.5
Kullingsjö, J.6
Pettersson, F.7
Sonesson, C.8
Waters, E.S.9
|