-
1
-
-
34250621337
-
Chemical genetics: Elucidating biological systems with small-molecule compounds
-
Kawasumi, M. and P. Nghiem, Chemical genetics: elucidating biological systems with small-molecule compounds. J Invest Dermatol, 2007. 127(7): p. 1577-84.
-
(2007)
J Invest Dermatol
, vol.127
, Issue.7
, pp. 1577-1584
-
-
Kawasumi, M.1
Nghiem, P.2
-
2
-
-
0037305949
-
Forward chemical genetics: Progress and obstacles on the path to a new pharmacopoeia
-
Lokey, R.S., Forward chemical genetics: progress and obstacles on the path to a new pharmacopoeia. Curr Opin Chem Biol, 2003. 7(1): p. 91-6.
-
(2003)
Curr Opin Chem Biol
, vol.7
, Issue.1
, pp. 91-96
-
-
Lokey, R.S.1
-
3
-
-
0037079065
-
Chemical genetic screening approaches to neurobiology
-
Stockwell, B.R., Chemical genetic screening approaches to neurobiology. Neuron, 2002. 36(4): p. 559-62.
-
(2002)
Neuron
, vol.36
, Issue.4
, pp. 559-562
-
-
Stockwell, B.R.1
-
5
-
-
44949211383
-
Finding the Critical Path: Applying the Semantic Web to Drug Discovery and Development
-
Neumann, E., Finding the Critical Path: Applying the Semantic Web to Drug Discovery and Development. DRUG DISCOVERY WORLD, 2005. 19(45): p. 8.
-
(2005)
DRUG DISCOVERY WORLD
, vol.19
, Issue.45
, pp. 8
-
-
Neumann, E.1
-
6
-
-
44949189564
-
-
PubChem
-
PubChem: http://pubchem.ncbi.nlm.nih.gov/.
-
-
-
-
7
-
-
13444273448
-
-
Bairoch, A., et al., The Universal Protein Resource (UniProt). Nucleic Acids Res, 2005. 33(Database issue): p. D154-9.
-
Bairoch, A., et al., The Universal Protein Resource (UniProt). Nucleic Acids Res, 2005. 33(Database issue): p. D154-9.
-
-
-
-
8
-
-
13444262395
-
-
Brooksbank, C., G. Cameron, and J. Thornton, The European Bioinformatics Institute's data resources: towards systems biology. Nucleic Acids Res, 2005. 33(Database issue): p. D46-53.
-
Brooksbank, C., G. Cameron, and J. Thornton, The European Bioinformatics Institute's data resources: towards systems biology. Nucleic Acids Res, 2005. 33(Database issue): p. D46-53.
-
-
-
-
9
-
-
0037805576
-
-
Kanehisa, M., The KEGG database. Novartis Found Symp, 2002. 247: p. 91-101; discussion 101-3, 119-28, 244-52.
-
Kanehisa, M., The KEGG database. Novartis Found Symp, 2002. 247: p. 91-101; discussion 101-3, 119-28, 244-52.
-
-
-
-
10
-
-
33644876210
-
-
Wishart, D.S., et al., DrugBank: a comprehensive resource for in silico drug discovery and exploration. Nucleic Acids Res, 2006. 34(Database issue): p. D668-72.
-
Wishart, D.S., et al., DrugBank: a comprehensive resource for in silico drug discovery and exploration. Nucleic Acids Res, 2006. 34(Database issue): p. D668-72.
-
-
-
-
11
-
-
27744460659
-
PharmGKB: The pharmacogenetics and pharmacogenomics knowledge base
-
Thorn, C.F., T.E. Klein, and R.B. Altman, PharmGKB: the pharmacogenetics and pharmacogenomics knowledge base. Methods Mol Biol, 2005. 311: p. 179-91.
-
(2005)
Methods Mol Biol
, vol.311
, pp. 179-191
-
-
Thorn, C.F.1
Klein, T.E.2
Altman, R.B.3
-
12
-
-
33749335282
-
The Connectivity Map: Using gene-expression signatures to connect small molecules, genes, and disease
-
Lamb, J., et al., The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease. Science, 2006. 313(5795): p. 1929-35.
-
(2006)
Science
, vol.313
, Issue.5795
, pp. 1929-1935
-
-
Lamb, J.1
-
13
-
-
27244447569
-
-
Neumann, E., A life science Semantic Web: are we there yet? Sci STKE, 2005. 2005(283): p. pe22.
-
Neumann, E., A life science Semantic Web: are we there yet? Sci STKE, 2005. 2005(283): p. pe22.
-
-
-
-
15
-
-
0034069495
-
Gene ontology: Tool for the unification of biology. The Gene Ontology Consortium
-
Ashburner, M., et al., Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat Genet, 2000. 25(1): p. 25-9.
-
(2000)
Nat Genet
, vol.25
, Issue.1
, pp. 25-29
-
-
Ashburner, M.1
-
16
-
-
0345863927
-
-
Bodenreider, O., The Unified Medical Language System (UMLS): integrating biomedical terminology. Nucleic Acids Res, 2004. 32 (Database issue): p. D267-70.
-
Bodenreider, O., The Unified Medical Language System (UMLS): integrating biomedical terminology. Nucleic Acids Res, 2004. 32 (Database issue): p. D267-70.
-
-
-
-
17
-
-
44949170735
-
-
gene_info: ftp://ftp.ncbi.nlm.nih.gov/gene/DA TA/gene_info.gz.
-
gene_info: ftp://ftp.ncbi.nlm.nih.gov/gene/DA TA/gene_info.gz.
-
-
-
-
18
-
-
44949157933
-
-
NCBI Interactions
-
NCBI Interactions: ftp://ftp.ncbi.nlm.nih.gov/gene/GeneRIF/ interactions.gz.
-
-
-
-
19
-
-
0037245913
-
BIND: The Biomolecular Interaction Network Database
-
Bader, G.D., D. Betel, and C.W. Hogue, BIND: the Biomolecular Interaction Network Database. Nucleic Acids Res, 2003. 31(1): p. 248-50.
-
(2003)
Nucleic Acids Res
, vol.31
, Issue.1
, pp. 248-250
-
-
Bader, G.D.1
Betel, D.2
Hogue, C.W.3
-
20
-
-
33644873184
-
-
Stark, C., et al., BioGRID: a general repository for interaction datasets. Nucleic Acids Res, 2006. 34(Database issue): p. D535-9.
-
Stark, C., et al., BioGRID: a general repository for interaction datasets. Nucleic Acids Res, 2006. 34(Database issue): p. D535-9.
-
-
-
-
21
-
-
33644877439
-
-
Mishra, G.R., et al., Human protein reference database-2006 update. Nucleic Acids Res, 2006. 34(Database issue): p. D411-4.
-
Mishra, G.R., et al., Human protein reference database-2006 update. Nucleic Acids Res, 2006. 34(Database issue): p. D411-4.
-
-
-
-
22
-
-
44949194818
-
-
BioCarta
-
BioCarta: http://www.biocarta.com/.
-
-
-
-
23
-
-
13444259844
-
-
Joshi-Tope, G., et al., Reactome: a knowledgebase of biological pathways. Nucleic Acids Res, 2005. 33(Database issue): p. D428-32.
-
Joshi-Tope, G., et al., Reactome: a knowledgebase of biological pathways. Nucleic Acids Res, 2005. 33(Database issue): p. D428-32.
-
-
-
-
24
-
-
44949181874
-
-
GO in RDF/XML: http://archive.geneontology.org/latesttermdb/go_daily- termdb.rdfxml.gz.
-
GO in RDF/XML
-
-
-
25
-
-
44949227014
-
-
gene2go: ftp://ftp. ncbi. nlm.nih.gov/gene/DATA/gene2go.gz
-
gene2go: ftp://ftp. ncbi. nlm.nih.gov/gene/DATA/gene2go.gz
-
-
-
-
26
-
-
13444266370
-
-
Hamosh, A., et al., Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders. Nucleic Acids Res, 2005. 33(Database issue): p. D514-7.
-
Hamosh, A., et al., Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders. Nucleic Acids Res, 2005. 33(Database issue): p. D514-7.
-
-
-
-
27
-
-
44949174068
-
-
XERCES: http://xerces.apache.org/xerces-j/.
-
XERCES: http://xerces.apache.org/xerces-j/.
-
-
-
-
28
-
-
44949230262
-
-
mim2gene: ftp://ftp. ncbi. nlm.nih.gov/gene/DATA/mim2gene
-
mim2gene: ftp://ftp. ncbi. nlm.nih.gov/gene/DATA/mim2gene
-
-
-
-
29
-
-
44949210477
-
-
Noy NF, CM., Fergerson RW, Knublauch H, Tu SW, Vendetti J, Musen MA. Protégé-2000: an open-source ontology-development and knowledge-acquisition environment. in AMIA Annu Symp Pro.
-
Noy NF, CM., Fergerson RW, Knublauch H, Tu SW, Vendetti J, Musen MA. Protégé-2000: an open-source ontology-development and knowledge-acquisition environment. in AMIA Annu Symp Pro.
-
-
-
-
30
-
-
44949172624
-
-
PROMPTVIZ: http: //www.thechiselgroup. org/≃chisel/projects/promp tviz/promptviz.html.
-
PROMPTVIZ: http
-
-
-
31
-
-
44949230263
-
-
OWL VIZ
-
OWL VIZ: http://www.co-ode.org/downloads/owlviz/
-
-
-
-
33
-
-
44949085553
-
An experiment in integrating large biomedical knowledge resources with RDF: Application to associating genotype and phenotype information. in WWW2007-Workshop on Healthcare and Life Sciences
-
Satya S. Sahoo, O.B., Kelly Zeng, Amit Sheth. An experiment in integrating large biomedical knowledge resources with RDF: Application to associating genotype and phenotype information. in WWW2007-Workshop on Healthcare and Life Sciences. BANFF: Proceedings of the WWW2007.
-
BANFF: Proceedings of the WWW2007
-
-
Satya, S.1
Sahoo, O.B.2
Zeng, K.3
Sheth, A.4
-
34
-
-
0035160066
-
A cholesterol-lowering drug reduces beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease
-
Refolo, L.M., et al., A cholesterol-lowering drug reduces beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease. Neurobiol Dis, 2001. 8(5): p. 890-9.
-
(2001)
Neurobiol Dis
, vol.8
, Issue.5
, pp. 890-899
-
-
Refolo, L.M.1
-
35
-
-
4444261661
-
Cholesterol homeostasis and the pathophysiology of Alzheimer's disease
-
Blain, J.F. and J. Poirier, Cholesterol homeostasis and the pathophysiology of Alzheimer's disease. Expert Rev Neurother, 2004. 4(5): p. 823-9.
-
(2004)
Expert Rev Neurother
, vol.4
, Issue.5
, pp. 823-829
-
-
Blain, J.F.1
Poirier, J.2
-
36
-
-
20844440894
-
Atorvastatin for the treatment of mild to moderate Alzheimer disease: Preliminary results
-
Sparks, D.L., et al., Atorvastatin for the treatment of mild to moderate Alzheimer disease: preliminary results. Arch Neurol, 2005. 62(5): p. 753-7.
-
(2005)
Arch Neurol
, vol.62
, Issue.5
, pp. 753-757
-
-
Sparks, D.L.1
-
37
-
-
33645672459
-
Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome
-
Habashi, J.P., et al., Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome. Science, 2006. 312(5770): p. 117-21.
-
(2006)
Science
, vol.312
, Issue.5770
, pp. 117-121
-
-
Habashi, J.P.1
-
38
-
-
33746156959
-
Global mapping of pharmacological space
-
Paolini, G.V., et al., Global mapping of pharmacological space. Nat Biotechnol, 2006. 24(7): p. 805-15.
-
(2006)
Nat Biotechnol
, vol.24
, Issue.7
, pp. 805-815
-
-
Paolini, G.V.1
-
39
-
-
0037791771
-
Activation of complement in the central nervous system: Roles in neurodegeneration and neuroprotection
-
van Beek, J., K. Elward, and P. Gasque, Activation of complement in the central nervous system: roles in neurodegeneration and neuroprotection. Ann N Y Acad Sci, 2003. 992: p. 56-71.
-
(2003)
Ann N Y Acad Sci
, vol.992
, pp. 56-71
-
-
van Beek, J.1
Elward, K.2
Gasque, P.3
-
40
-
-
0037322558
-
Formation of complement membrane attack complex in mammalian cerebral cortex evokes seizures and neurodegeneration
-
Xiong, Z.Q., et al., Formation of complement membrane attack complex in mammalian cerebral cortex evokes seizures and neurodegeneration. J Neurosci, 2003. 23(3): p. 955-60.
-
(2003)
J Neurosci
, vol.23
, Issue.3
, pp. 955-960
-
-
Xiong, Z.Q.1
-
41
-
-
0033061855
-
Up-regulated production and activation of the complement system in Alzheimer's disease brain
-
Yasojima, K., et al., Up-regulated production and activation of the complement system in Alzheimer's disease brain. Am J Pathol, 1999. 154(3): p. 927-36.
-
(1999)
Am J Pathol
, vol.154
, Issue.3
, pp. 927-936
-
-
Yasojima, K.1
-
42
-
-
6344241861
-
Characterization of C3a and C5a receptors in rat cerebellar granule neurons during maturation. Neuroprotective effect of C5a against apoptotic cell death
-
Benard, M., et al., Characterization of C3a and C5a receptors in rat cerebellar granule neurons during maturation. Neuroprotective effect of C5a against apoptotic cell death. J Biol Chem, 2004. 279(42): p. 43487-96.
-
(2004)
J Biol Chem
, vol.279
, Issue.42
, pp. 43487-43496
-
-
Benard, M.1
-
43
-
-
2342558048
-
Innate immunity in Alzheimer's disease: A model for local inflammatory reactions
-
McGeer, E.G. and P.L. McGeer, Innate immunity in Alzheimer's disease: a model for local inflammatory reactions. Mol Interv, 2001. 1(1): p. 22-9.
-
(2001)
Mol Interv
, vol.1
, Issue.1
, pp. 22-29
-
-
McGeer, E.G.1
McGeer, P.L.2
-
44
-
-
33746505701
-
Therapeutic activity of C5a receptor antagonists in a rat model of neurodegeneration
-
Woodruff, T.M., et al., Therapeutic activity of C5a receptor antagonists in a rat model of neurodegeneration. Faseb J, 2006. 20(9): p. 1407-17.
-
(2006)
Faseb J
, vol.20
, Issue.9
, pp. 1407-1417
-
-
Woodruff, T.M.1
-
45
-
-
1942517427
-
Involvement of Islet-2 in the Slit signaling for axonal branching and defasciculation of the sensory neurons in embryonic zebrafish
-
Yeo, S.Y., et al., Involvement of Islet-2 in the Slit signaling for axonal branching and defasciculation of the sensory neurons in embryonic zebrafish. Mech Dev, 2004. 121(4): p. 315-24.
-
(2004)
Mech Dev
, vol.121
, Issue.4
, pp. 315-324
-
-
Yeo, S.Y.1
-
46
-
-
0036617758
-
Slit2, a branching-arborization factor for sensory axons in the Mammalian CNS
-
Ozdinler, P.H. and R.S. Erzurumlu, Slit2, a branching-arborization factor for sensory axons in the Mammalian CNS. J Neurosci, 2002. 22(11): p. 4540-9.
-
(2002)
J Neurosci
, vol.22
, Issue.11
, pp. 4540-4549
-
-
Ozdinler, P.H.1
Erzurumlu, R.S.2
-
47
-
-
1642447149
-
Calcium signaling in chemorepellant Slit2-dependent regulation of neuronal migration
-
Xu, H.T., et al., Calcium signaling in chemorepellant Slit2-dependent regulation of neuronal migration. Proc Natl Acad Sci U S A, 2004. 101(12): p. 4296-301.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, Issue.12
, pp. 4296-4301
-
-
Xu, H.T.1
-
48
-
-
44949115160
-
-
Gudivada, Qu A.X. Jegga, AG, Neumann E.K, Aronow, B.J., A Genome - Phenome Integrated Approach for Mining Disease Genes using Semantic Web. WWW2007 Workshop on Healthcare and Life Sciences. 2007. BANFF: Proceedings of the WWW2007.
-
Gudivada, Qu A.X. Jegga, AG, Neumann E.K, Aronow, B.J., A Genome - Phenome Integrated Approach for Mining Disease Genes using Semantic Web. WWW2007 Workshop on Healthcare and Life Sciences. 2007. BANFF: Proceedings of the WWW2007.
-
-
-
-
49
-
-
44949225131
-
-
S. Brin, L.P. The Anatomy of a Large-Scale Hypertextual Web Search Engine. in WWW7 / Computer Networks 1998: Proceedings of the seventh international conference on World Wide Web 7.
-
S. Brin, L.P. The Anatomy of a Large-Scale Hypertextual Web Search Engine. in WWW7 / Computer Networks 1998: Proceedings of the seventh international conference on World Wide Web 7.
-
-
-
|