Production of glycerol from glucose by coexpressing glycerol-3-phosphate dehydrogenase and glycerol-3-phosphatase in Klebsiella pneumoniae

Journal of Bioscience and Bioengineering

Volumn 105, Issue 5, 2008, Pages 508-512

  Zheng, Yu ^a   Zhao, Li ^a   Zhang, Jianguo ^a   Zhang, Haiyi ^a   Ma, Xingyuan ^a   Wei, Dongzhi ^a  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

1,3 propanediol; glycerol; glycerol 3 phosphatase; glycerol 3 phosphate dehydrogenase; Klebsiella pneumoniae

Indexed keywords

BIOCHEMICAL ENGINEERING; BLOOD VESSEL PROSTHESES; ELECTRIC CONDUCTIVITY MEASUREMENT; ELECTRIC MACHINE INSULATION; ENZYMES; GLUCOSE; HEALTH; MICROFLUIDICS; PALLADIUM; PROGRAMMING THEORY; PROTEINS;

GENES CODING; GLYCEROL CONCENTRATION; GLYCEROL PRODUCTION; KLEBSIELLA PNEUMONIAE; PROPANEDIOL; RECOMBINANT PROTEINS; WILD-TYPE (WT);

GLYCEROL;

GLUCOSE; GLYCEROL 3 PHOSPHATASE; GLYCEROL 3 PHOSPHATE DEHYDROGENASE; PHOSPHATASE;

ARTICLE; BACTERIAL METABOLISM; BIOREACTOR; FERMENTATION; GENETIC ENGINEERING; GLUCOSE METABOLISM; KLEBSIELLA PNEUMONIAE; LIPOGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PH;

GENETIC ENHANCEMENT; GLUCOSE; GLYCEROL; GLYCEROLPHOSPHATE DEHYDROGENASE; KLEBSIELLA PNEUMONIAE; PHOSPHORIC MONOESTER HYDROLASES; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE;

KLEBSIELLA PNEUMONIAE;

EID: 44949148079     PISSN: 13891723     EISSN: None     Source Type: Journal    
DOI: 10.1263/jbb.105.508     Document Type: Article

References (19)

1. Wang Z.X., Zhu-ge J., Fang H.Y., and Prior B.A. Glycerol production by microbial fermentation: a review. Biotechnol. Adv. 19 (2001) 201-223
2. Zeng A.P., and Biebl H. Bulk chemicals from biotechnology: the case of 1,3-propanediol production and the new trends. Adv. Biochem. Eng./Biotechnol. 74 (2002) 239-259
3. Homann T., Tag C., Biebl H., Deckwer W.D., and Schink B. Fermentation of glycerol by Klebsiella and Citrobacter strains. Appl. Microbiol. Biotechnol. 33 (1990) 121-126
4. Boenigk R., Bowien S., and Gottschalk G. Fermentation of glycerol to 1,3-propanediol in continuous cultures of Citrobacter freundii. Appl. Microbiol. Biotechnol. 38 (1993) 453-457
5. Ahrens K., Menzel K., Zeng A.P., and Deckwer W.D. Kinetic, dynamic, and pathway studies of glycerol metabolism by Klebsiella pneumoniae in anaerobic continuous culture: III. enzymes and fluxes of glycerol dissimilation and 1,3-Propanediol formation. Biotechnol. Bioeng. 59 (1998) 544-552
6. Papanikolaou S., Fick M., and Aggelis G. The effect of raw glycerol concentration on the production of 1,3-propanediol by Clostridium butyricum. J. Chem. Technol. Biotechnol. 79 (2004) 1189-1196
7. Hartlep M., Hussmann W., Prayitno N., Meynial-Salles I., and Zeng A.P. Study of two-stage processes for the microbial production of 1,3-propanediol from glucose. Appl. Microbiol. Biotechnol. 60 (2002) 60-66
8. Bakker B.M., Overkamp K.M., van Maris A.J., Kotter P., Luttik M.A., van Dijken J.P., and Pronk J.T. Stoichiometry and compartmentation of NADH metabolism in Saccharomyces cerevisiae. FEMS Microbiol. Rev. 25 (2001) 15-37
9. Hohmann S. Osmotic stress signaling and osmoadaptation in yeasts. Microbiol. Mol. Biol. Rev. 66 (2002) 300-372
10. Påhlman A.K., Granath K., Ansell R., Hohmann S., and Adler L. The yeast glycerol 3-phosphatases Gpp1p and Gpp2p are required for glycerol biosynthesis and differentially involved in the cellular responses to osmotic, anaerobic, and oxidative stress. J. Biol. Chem. 276 (2001) 3555-3563
11. Remize F., Barnavon L., and Dequin S. Glycerol export and glycerol-3-phosphate dehydrogenase, but not glycerol phosphatase, are rate limiting for glycerol production in Saccharomyces cerevisiae. Metab. Eng. 3 (2001) 301-312
12. +). Yeast 21 (2004) 119-126
13. Meynial Salles I., Forchhammer N., Croux C., Girbal L., and Soucaillea P. Evolution of a Saccharomyces cerevisiae metabolic pathway in Escherichia coli. Metab. Eng. 9 (2007) 152-159
14. Cameron D.C., Altaras N.E., Hoffman M.L., and Shaw A.J. Metabolic engineering of propanediol pathways. Biotechnol. Prog. 14 (1998) 116-125
15. Sambrook J., Fitsch E.F., and Maniatis T. Molecular cloning: a laboratory manual [M]. 3rd ed. (1989), Cold Spring Harbor Laboratory Press, New York
16. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities utilizing the principle of protein dye binding. Anal. Biochem. 72 (1976) 248-254
17. Biebl H., Zeng A.P., Menzel K., and Deckwer W.D. Fermentation of glycerol to 1,3-propanediol and 2,3-butanediol by Klebsiella pneumoniae. Appl. Microbiol. Biotechnol. 50 (1998) 24-29
18. Cheng K.K., Zhang J.A., and Liu D.H. Production of 1,3-propanediol by Klebsiella pneumoniae from glycerol broth. Biotechnol. Lett. 28 (2006) 1817-1821
19. Forage R.G., and Lin E.C.C. Dha system mediating aerobic and anaerobic dissimilation of glycerol in Klebsiella pneumoniae NCIB 418. J. Bacteriol. 151 (1982) 591-599