Mannose-binding lectin (MBL) facilitates opsonophagocytosis of yeasts but not of bacteria despite MBL binding

Journal of Immunology

Volumn 180, Issue 6, 2008, Pages 4124-4132

  Brouwer, Nannette ^a   Dolman, Koert M ^a,b   Van Houdt, Michel ^a   Sta, Marleen ^a   Roos, Dirk ^a   Kuijpers, Taco W ^a,b  

^a SANQUIN RESEARCH   (Netherlands)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C3; LECTIN; MANNOSE BINDING LECTIN; ZYMOSAN; OPSONIN;

ARTICLE; CANDIDA ALBICANS; COMPLEMENT ACTIVATION; COMPLEMENT DEPOSITION; CONTROLLED STUDY; ESCHERICHIA COLI; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MALE; NEUTROPHIL; NONHUMAN; OPSONIZATION; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN BINDING; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIAE; BLOOD; COMPARATIVE STUDY; COMPLEMENT ALTERNATIVE PATHWAY; CYTOLOGY; IMMUNOLOGY; METABOLISM; MICROBIOLOGY; PHYSIOLOGY; SACCHAROMYCES CEREVISIAE;

CANDIDA ALBICANS; COMPLEMENT C3; COMPLEMENT PATHWAY, ALTERNATIVE; ESCHERICHIA COLI; FEMALE; HUMANS; MALE; MANNOSE-BINDING LECTIN; NEUTROPHILS; OPSONIN PROTEINS; PHAGOCYTOSIS; PROTEIN BINDING; SACCHAROMYCES CEREVISIAE; STAPHYLOCOCCUS AUREUS;

EID: 44849113967     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.180.6.4124     Document Type: Article

References (34)

1. Holmskov, U., S. Thiel, and J. C. Jensenius. 2003. Collections and ficolins: humoral lectins of the innate immune defense. Annu. Rev. Immunol. 21: 547-578.
2. Garred, P., F. Larsen, J. Seyfarth, R. Fujita, and H. O. Madsen. 2006. Mannose-binding lectin and its genetic variants. Genes Immun. 7: 85-94.
3. Madsen, H. O., P. Garred, S. Thiel, J. A. Kurtzhals, L. U. Lamm, L. P. Ryder, and A. Svejgaard. 1995. Interplay between promoter and structural gene variants control basal serum level of mannan-binding protein. J. Immunol. 155: 3013-3020.
4. Garred, P., F. Larsen, H. O. Madsen, and C. Koch. 2003. Mannose-binding lectin deficiency: revisited. Mol. Immunol. 40: 73-84.
5. Steffensen, R., S. Thiel, K. Varming, C. Jersild, and J. C. Jensenius. 2000. Detection of structural gene mutations and promoter polymorphisms in the mannan-binding lectin (MBL) gene by polymerase chain reaction with sequence-specific primers. J. Immunol. Methods 241: 33-42.
6. Brouwer, N., K. M. Dolman, R. van Zwieten, E. Nieuwenhuys, M. Hart, L. A. Aarden, D. Roos, and T. W. Kuijpers. 2006. Mannan-binding lectin (MBL)-mediated opsonization is enhanced by the alternative pathway amplification loop. Mol. Immunol. 43: 2051-2060.
7. Jack, D. L., N. J. Klein, and M. W. Turner. 2001. Mannose-binding lectin: targeting the microbial world for complement attack and opsonophagocytosis. Immunol. Rev. 180: 86-99.
8. Neth, O., D. L. Jack, A. W. Dodds, H. Holzel, N. J. Klein, and M. W. Turner. 2000. Mannose-binding lectin binds to a range of clinically relevant microorganisms and promotes complement deposition. Infect. Immun. 68: 688-693.
9. Turner, M. W. 1998. Mannose-binding lectin (MBL) in health and disease. Immunobiology 199: 327-339.
10. Eisen, D. P., and R. M. Minchinton. 2003. Impact of mannose-binding lectin on susceptibility to infectious diseases. Clin. Infect. Dis. 37: 1496-1505.
11. Schwaeble, W., M. R. Dahl, S. Thiel, C. Stover, and J. C. Jensenius. 2002. The mannan-binding lectin-associated serine proteases (MASPs) and MAp19: four components of the lectin pathway activation complex encoded by two genes. Immunobiology 205: 455-466.
12. Vorup-Jensen, T., J. C. Jensenius, and S. Thiel. 1998. MASP-2, the C3 convertase generating protease of the MBLectin complement activating pathway. Immunobiology 199: 348-357.
13. Moller-Kristensen, M., S. Thiel, A. Sjoholm, M. Matsushita, and J. C. Jensenius. 2007. Cooperation between MASP-1 and MASP-2 in the generation of C3 convertase through the MBL pathway. Int. Immunol. 19: 141-149.
14. Petersen, S. V., S. Thiel, L. Jensen, R. Steffensen, and J. C. Jensenius. 2001. An assay for the mannan-binding lectin pathway of complement activation. J. Immunol. Methods 257: 107-116.
15. Fijen, C. A., E. J. Kuijper, A. J. Hannema, A. G. Sjoholm, and J. P. van Putten. 1989. Complement deficiencies in patients over ten years old with meningococcal disease due to uncommon serogroups. Lancet 2: 585-588.
16. Frakking, F. N., M. D. van de Wetering, N. Brouwer, K. M. Dolman, J. Geissler, B. Lemkes, H. N. Caron, and T. W. Kuijpers. 2006. The role of mannose-binding lectin (MBL) in paediatric oncology patients with febrile neutropenia. Eur. J. Cancer 42: 909-916.
17. Roos, D., and M. de Boer. 1986. Purification and cryopreservation of phagocytes from human blood. Methods Enzymol. 132: 225-243.
18. Hoekzema, R., M. Martens, M. C. Brouwer, and C. E. Hack. 1988. The distortive mechanism for the activation of complement component C1 supported by studies with a monoclonal antibody against the "arms" of C1q. Mol. Immunol. 25: 485-494.
19. McGrath, F. D., M. C. Brouwer, G. J. Arlaud, M. R. Daha, C. E. Hack, and A. Roos. 2006. Evidence that complement protein C1q interacts with C-reactive protein through its globular head region. J. Immunol. 176: 2950-2957.
20. Katragadda, M., P. Magotti, G. Sfyroera, and J. D. Lambris. 2006. Hydrophobic effect and hydrogen bonds account for the improved activity of a complement inhibitor, compstatin. J. Med. Chem. 49: 4616-4622.
21. van Mirre, E., W. B. Breunis, J. Geissler, C. E. Hack, M. de Boer, D. Roos, and T. W. Kuijpers. 2006. Neutrophil responsiveness to IgG, as determined by fixed ratios of mRNA levels for activating and inhibitory FcγRII (CD32), is stable over time and unaffected by cytokines. Blood 108: 584-590.
22. Laursen, I., G. Houen, P. Hojrup, N. Brouwer, L. B. Krogsoe, L. Blou, and P. R. Hansen. 2007. Second-generation nanofiltered plasma-derived mannan-binding lectin product: process and characteristics. Vox Sang. 92: 338-350.
23. Krarup, A., U. B. Sorensen, M. Matsushita, J. C. Jensenius, and S. Thiel. 2005. Effect of capsulation of opportunistic pathogenic bacteria on binding of the pattern recognition molecules mannan-binding lectin, L-ficolin, and H-ficolin. Infect. Immun. 73: 1052-1060.
24. Neth, O., D. L. Jack, M. Johnson, N. J. Klein, and M. W. Turner. 2002. Enhancement of complement activation and opsonophagocytosis by complexes of mannose-binding lectin with mannose-binding lectin-associated serine protease after binding to Staphylococcus aureus. J. Immunol. 169: 4430-4436.
25. Lynch, N. J., S. Roscher, T. Hartung, S. Morath, M. Matsushita, D. N. Maennel, M. Kuraya, T. Fujita, and W. J. Schwaeble. 2004. L-ficolin specifically binds to lipoteichoic acid, a cell wall constituent of Gram-positive bacteria, and activates the lectin pathway of complement. J. Immunol. 172: 1198-1202.
26. Shi, L., K. Takahashi, J. Dundee, S. Shahroor-Karni, S. Thiel, J. C. Jensenius, F. Gad, M. R. Hamblin, K. N. Sastry, and R. A. Ezekowitz. 2004. Mannose-binding lectin-deficient mice are susceptible to infection with Staphylococcus aureus. J. Exp. Med. 199: 1379-1390.
27. Roy, S., K. Knox, S. Segal, D. Griffiths, C. E. Moore, K. I. Welsh, A. Smarason, N. P. Day, W. L. McPheat, D. W. Crook, and A. V. Hill. 2002. MBL genotype and risk of invasive pneumococcal disease: a case-control study. Lancet 359: 1569-1573.
28. Kronborg, G., N. Weis, H. O. Madsen, S. S. Pedersen, C. Wejse, H. Nielsen, P. Skinhoj, and P. Garred. 2002. Variant mannose-binding lectin alleles are not associated with susceptibility to or outcome of invasive pneumococcal infection in randomly included patients. J. Infect. Dis. 185: 1517-1520.
29. Moens, L., E. Van Hoeyveld, W. E. Peetermans, C. De Boeck, J. Verhaegen, and X. Bossuyt. 2006. Mannose-binding lectin genotype and invasive pneumococcal infection. Hum. Immunol. 67: 605-611.
30. Selander, B., H. Kayhty, E. Wedege, E. Holmstrom, L. Truedsson, C. Soderstrom, and A. G. Sjoholm. 2000. Vaccination responses to capsular polysaccharides of Neisseria meningitidis and Haemophilus influenzae type b in two C2-deficient sisters: alternative pathway-mediated bacterial killing and evidence for a novel type of blocking IgG. J. Clin. Immunol. 20: 138-149.
31. Proulx, F., E. Wagner, B. Toledano, H. Decaluwe, E. G. Seidman, and G. E. Rivard. 2003. Mannan-binding lectin in children with Escherichia coli O157:H7 haemmorrhagic colitis and haemolytic uraemic syndrome. Clin. Exp. Immunol. 133: 360-363.
32. Lillegard, J. B., R. B. Sim, P. Thorkildson, M. A. Gates, and T. R. Kozel. 2006. Recognition of Candida albicans by mannan-binding lectin in vitro and in vivo. J. Infect. Dis. 193: 1589-1597.
33. Ip, W. K., K. H. Chan, H. K. Law, G. H. Tso, E. K. Kong, W. H. Wong, Y. F. To, R. W. Yung, E. Y. Chow, K. L. Au, et al. 2005. Mannose-binding lectin in severe acute respiratory syndrome coronavirus infection. J. Infect. Dis. 191: 1697-1704.
34. Aoyagi, Y., E. E. Adderson, C. E. Rubens, J. F. Bohnsack, J. G. Min, M. Matsushita, T. Fujita, Y. Okuwaki, and S. Takahashi. 2007. L-ficolin/mannose- binding lectin-associated serine protease complexes bind to group B streptococci largely through N-acetylneuraminic acid of capsular polysaccharide, and activate the complement pathway. Infect. Immun.