COUP-TFI modulates estrogen signaling and influences proliferation, survival and migration of breast cancer cells

Breast Cancer Research and Treatment

Volumn 110, Issue 1, 2008, Pages 69-83

  Le Dily, François ^a   Métivier, Raphaël ^a   Guéguen, Marie Madeleine ^a   Le Péron, Christine ^a   Flouriot, Gilles ^a   Tas, Patrick ^b   Pakdel, Farzad ^a  

^a CNRS   (France)

^b PONTCHAILLOU UNIVERSITY HOSPITAL   (France)

Author keywords

Breast cancer; COUP TFI; Estrogen receptor; Proliferation differentiation; Transcription

Indexed keywords

CHICKEN OVALBUMIN UPSTREAM PROMOTER TRANSCRIPTION FACTOR 1; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR ALPHA; RNA HELICASE; SERINE;

APOPTOSIS; ARTICLE; BREAST CANCER; BREAST CELL; CANCER CELL; CANCER GROWTH; CATHEPSIN D GENE; CELL CYCLE PROGRESSION; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; CHROMATIN IMMUNOPRECIPITATION; COMPARATIVE STUDY; CONTROLLED STUDY; GENE; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

BREAST NEOPLASMS; CATHEPSIN D; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; COUP TRANSCRIPTION FACTOR I; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; NEOPLASM INVASIVENESS; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

EID: 44849112135     PISSN: 01676806     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10549-007-9693-6     Document Type: Article

References (54)

1. Sommer S, Fuqua SA (2001) Estrogen receptor and breast cancer. Semin Cancer Biol 11(5):339-352
2. Nilsson S, Makela S, Treuter E et al (2001) Mechanisms of estrogen action. Physiol Rev 81(4):1535-1565
3. Safe S (2001) Transcriptional activation of genes by 17 beta-estradiol through estrogen receptor-Sp1 interactions. Vitam Horm 62:231-252
4. Klinge CM (2000) Estrogen receptor interaction with co-activators and co-repressors. Steroids 65(5):227-251
5. Endoh H, Maruyama K, Masuhiro Y et al (1999) Purification and identification of p68 RNA helicase acting as a transcriptional coactivator specific for the activation function 1 of human estrogen receptor alpha. Mol Cell Biol 19(8):5363-5372
6. Watanabe M, Yanagisawa J, Kitagawa H et al (2001) A subfamily of RNA-binding DEAD-box proteins acts as an estrogen receptor alpha coactivator through the N-terminal activation domain (AF-1) with an RNA coactivator, SRA. Embo J 20(6):1341-1352
7. Gadducci A, Biglia N, Sismondi P et al (2005) Breast cancer and sex steroids: critical review of epidemiological, experimental and clinical investigations on etiopathogenesis, chemoprevention and endocrine treatment of breast cancer. Gynecol Endocrinol 20(6):343-360
8. Foster JS, Henley DC, Ahamed S et al (2001) Estrogens and cell-cycle regulation in breast cancer. Trends Endocrinol Metab 12(7):320-327
9. Gompel A, Somai S, Chaouat M et al (2000) Hormonal regulation of apoptosis in breast cells and tissues. Steroids 65(10-11):593-598
10. Osborne CK (1998) Steroid hormone receptors in breast cancer management. Breast Cancer Res Treat 51(3):227-238
11. Frasor J, Danes JM, Komm B et al (2003) Profiling of estrogen up- and down-regulated gene expression in human breast cancer cells: insights into gene networks and pathways underlying estrogenic control of proliferation and cell phenotype. Endocrinology 144(10):4562-4574
12. Deblois G, Giguere V (2003) Ligand-independent coactivation of ERalpha AF-1 by steroid receptor RNA activator (SRA) via MAPK activation. J Steroid Biochem Mol Biol 85(2-5):123-131
13. Métivier R, Gay FA, Hubner MR et al (2002) Formation of an hER alpha-COUP-TFI complex enhances hER alpha AF-1 through Ser118 phosphorylation by MAPK. Embo J 21(13):3443-3453
14. Burbach JP, Lopes da Silva S, Cox JJ et al (1994) Repression of estrogen-dependent stimulation of the oxytocin gene by chicken ovalbumin upstream promoter transcription factor I. J Biol Chem 269(21):15046-15053
15. Liu Y, Yang N, Teng CT (1993) COUP-TF acts as a competitive repressor for estrogen receptor-mediated activation of the mouse lactoferrin gene. Mol Cell Biol 13(3):1836-1846
16. Tsai SY, Tsai MJ (1997) Chick ovalbumin upstream promoter-transcription factors (COUP-TFs): coming of age. Endocr Rev 18(2):229-240
17. Pereira FA, Qiu Y, Zhou G et al (1999) The orphan nuclear receptor COUP-TFII is required for angiogenesis and heart development. Genes Dev 13(8):1037-1049
18. Pereira FA, Tsai MJ, Tsai SY (2000) COUP-TF orphan nuclear receptors in development and differentiation. Cell Mol Life Sci 57(10):1388-1398
19. Qiu Y, Pereira FA, DeMayo FJ et al (1997) Null mutation of mCOUP-TFI results in defects in morphogenesis of the glossopharyngeal ganglion, axonal projection, and arborization. Genes Dev 11(15):1925-1937
20. Kieback DG, Levi T, Kohlberger P et al (1996) Chicken ovalbumin upstream promoter-transcription factor (COUP-TF) expression in human endometrial cancer cell lines. Anticancer Res 16(6B):3371-3376
21. Kieback DG, Runnebaum IB, Moebus VJ et al (1993) Chicken ovalbumin upstream promoter transcription factor (COUP-TF): an orphan steroid receptor with a specific pattern of differential expression in human ovarian cancer cell lines. Gynecol Oncol 51(2):167-170
22. Navab R, Gonzalez-Santos JM, Johnston MR et al (2004) Expression of chicken ovalbumin upstream promoter-transcription factor II enhances invasiveness of human lung carcinoma cells. Cancer Res 64(15):5097-5105
23. Merot Y, Metivier R, Penot G et al (2004) The relative contribution exerted by AF-1 and AF-2 transactivation functions in estrogen receptor alpha transcriptional activity depends upon the differentiation stage of the cell. J Biol Chem 279(25):26184-26191
24. Metivier R, Penot G, Hubner MR et al (2003) Estrogen receptor-alpha directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter. Cell 115(6):751-763
25. Keepers YP, Pizao PE, Peters GJ et al (1991) Comparison of the sulforhodamine B protein and tetrazolium (MTT) assays for in vitro chemosensitivity testing. Eur J Cancer 27(7):897-900
26. Lacroix M, Leclercq G (2004) Relevance of breast cancer cell lines as models for breast tumours: an update. Breast Cancer Res Treat 83(3):249-289
27. Klinge CM, Silver BF, Driscoll MD et al (1997) Chicken ovalbumin upstream promoter-transcription factor interacts with estrogen receptor, binds to estrogen response elements and half-sites, and inhibits estrogen-induced gene expression. J Biol Chem 272(50):31465-31474
28. Perry RR, Kang Y, Greaves B (1995) Effects of tamoxifen on growth and apoptosis of estrogen-dependent and -independent human breast cancer cells. Ann Surg Oncol 2(3):238-245
29. Platet N, Cathiard AM, Gleizes M et al (2004) Estrogens and their receptors in breast cancer progression: a dual role in cancer proliferation and invasion. Crit Rev Oncol Hematol 51(1):55-67
30. Platet N, Cunat S, Chalbos D et al (2000) Unliganded and liganded estrogen receptors protect against cancer invasion via different mechanisms. Mol Endocrinol 14(7):999-1009
31. Vincent-Salomon A, Thiery JP (2003) Host microenvironment in breast cancer development: epithelial-mesenchymal transition in breast cancer development. Breast Cancer Res 5(2):101-106
32. Adam F, Sourisseau T, Metivier R et al (2000) COUP-TFI (chicken ovalbumin upstream promoter-transcription factor I) regulates cell migration and axogenesis in differentiating P19 embryonal carcinoma cells. Mol Endocrinol 14(12):1918-1933
33. Garbett EA, Reed MW, Stephenson TJ et al (2000) Proteolysis in human breast cancer. Mol Pathol 53(2):99-106
34. Marshman E, Green KA, Flint DJ et al (2003) Insulin-like growth factor binding protein 5 and apoptosis in mammary epithelial cells. J Cell Sci 116(Pt 4):675-682
35. Williams TM, Medina F, Badano I et al (2004) Caveolin-1 gene disruption promotes mammary tumorigenesis and dramatically enhances lung metastasis in vivo. Role of Cav-1 in cell invasiveness and matrix metalloproteinase (MMP-2/9) secretion. J Biol Chem 279(49):51630-51646
36. Sparatore B, Patrone M, Passalacqua M et al (2005) Activation of A431 human carcinoma cell motility by extracellular high-mobility group box 1 protein and epidermal growth factor stimuli. Biochem J 389(Pt 1):215-221
37. More E, Fellner T, Doppelmayr H et al (2003) Activation of the MAP kinase pathway induces chicken ovalbumin upstream promoter-transcription factor II (COUP-TFII) expression in human breast cancer cell lines. J Endocrinol 176(1):83-94
38. Nakshatri H, Mendonca MS, Bhat-Nakshatri P et al (2000) The orphan receptor COUP-TFII regulates G2/M progression of breast cancer cells by modulating the expression/activity of p21(WAF1/CIP1), cyclin D1, and cdk2. Biochem Biophys Res Commun 270(3):1144-1153
39. Lin B, Chen GQ, Xiao D et al (2000) Orphan receptor COUP-TF is required for induction of retinoic acid receptor beta, growth inhibition, and apoptosis by retinoic acid in cancer cells. Mol Cell Biol 20(3):957-970
40. Lannigan DA (2003) Estrogen receptor phosphorylation. Steroids 68(1):1-9
41. Rochette-Egly C (2003) Nuclear receptors: integration of multiple signalling pathways through phosphorylation. Cell Signal 15(4):355-366
42. Britton DJ, Hutcheson IR, Knowlden JM et al (2006) Bidirectional cross talk between ERalpha and EGFR signalling pathways regulates tamoxifen-resistant growth. Breast Cancer Res Treat 96(2):131-146
43. Bunone G, Briand PA, Miksicek RJ et al (1996) Activation of the unliganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation. Embo J 15(9):2174-2183
44. Fujita T, Kobayashi Y, Wada O et al (2003) Full activation of estrogen receptor alpha activation function-1 induces proliferation of breast cancer cells. J Biol Chem 278(29):26704-26714
45. Bailey P, Sartorelli V, Hamamori Y et al (1998) The orphan nuclear receptor, COUP-TF II, inhibits myogenesis by post-transcriptional regulation of MyoD function: COUP-TF II directly interacts with p300 and myoD. Nucleic Acids Res 26(23):5501-5510
46. Eubank DW, Duplus E, Williams SC et al (2001) Peroxisome proliferator-activated receptor gamma and chicken ovalbumin upstream promoter transcription factor II negatively regulate the phosphoenolpyruvate carboxykinase promoter via a common element. J Biol Chem 276(32):30561-30569
47. Rochefort H, Garcia M, Glondu M et al (2000) Cathepsin D in breast cancer: mechanisms and clinical applications, a 1999 overview. Clin Chim Acta 291(2):157-170
48. Hall JM, Korach KS (2003) Stromal cell-derived factor 1, a novel target of estrogen receptor action, mediates the mitogenic effects of estradiol in ovarian and breast cancer cells. Mol Endocrinol 17(5):792-803
49. Damiens E, El Yazidi I, Mazurier J et al (1999) Lactoferrin inhibits G1 cyclin-dependent kinases during growth arrest of human breast carcinoma cells. J Cell Biochem 74(3):486-498
50. Cassoni P, Sapino A, Marrocco T et al (2004) Oxytocin and oxytocin receptors in cancer cells and proliferation. J Neuroendocrinol 16(4):362-364
51. Le Goff P, Montano MM, Schodin DJ et al (1994) Phosphorylation of the human estrogen receptor. Identification of hormone-regulated sites and examination of their influence on transcriptional activity. J Biol Chem 269:4458-4466
52. Giamarchi C, Solanas M, Chailleux C et al (1999) Chromatin structure of the regulatory regions of pS2 and cathepsin D genes in hormone-dependent and -independent breast cancer cell lines. Oncogene 18(2):533-541
53. Chalbos D, Philips A, Galtier F et al (1993) Synthetic antiestrogens modulate induction of pS2 and cathepsin-D messenger ribonucleic acid by growth factors and adenosine 3′,5′-monophosphate in MCF7 cells. Endocrinology 133(2):571-576
54. Wang F, Duan R, Chirgwin J et al (2000) Transcriptional activation of cathepsin D gene expression by growth factors. J Mol Endocrinol 24(2):193-202