Taenia solium: Antioxidant metabolism enzymes as targets for cestocidal drugs and vaccines

Current Topics in Medicinal Chemistry

Volumn 8, Issue 5, 2008, Pages 393-399

  Vaca Paniagua, F ^a   Torres Rivera, A ^a   Parra Unda, R ^a   Landa, A ^a  

^a UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

2 Cys peroxiredoxin; Antioxidant metabolism; Glutathione transferase; Superoxide dismutase; Taenia solium

Indexed keywords

ANTICESTODAL AGENT; ANTIOXIDANT; BENCIMIDAZOLE DERIVATIVE; COPPER ZINC SUPEROXIDE DISMUTASE; GLUTATHIONE TRANSFERASE; HYDROGEN PEROXIDE; IMIDAZOLE DERIVATIVE; PEROXIREDOXIN; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; VACCINE;

ANTIOXIDANT ACTIVITY; APOPTOSIS; CELL DIFFERENTIATION; CELL GROWTH; DRUG TARGETING; HOST PARASITE INTERACTION; HUMAN; IMMUNE RESPONSE; IMMUNIZATION; NONHUMAN; NUCLEOTIDE SEQUENCE; REVIEW; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; TAENIA SOLIUM;

ANIMALS; ANTHELMINTICS; ANTIOXIDANTS; TAENIA SAGINATA; VACCINES;

EID: 44849097478     PISSN: 15680266     EISSN: None     Source Type: Journal    
DOI: 10.2174/156802608783790857     Document Type: Review

References (64)

1. Willms, K.; Merchant, M. T.; Diaz, S.; Arcos, L. Host-parasite interface in the metacestode of Taenia solium. In Cysticercosis: Present state of knowledge and perspectives; Flisser, A.; Willms, K.; Laclette, J. P.; Ridaura, C.; Beltran, F.; Eds.; Academic Press: New York, 1982, pp. 397-411.
2. Sies, H. Strategies of antioxidants defense. Eur. J. Biochem. 1993, 15, 213-219.
3. Callahan, H. L.; Crouch, R. K.; James, R. E. Helminth anti-oxidant enzymes: A protective mechanisms against host oxidants. Parasitol Today 1988, 4, 218-225.
4. 2, a necessary evil for cell signaling. Science 2006, 312, 1882-1883.
5. Buetler, T. M.; Krauskopf, A.; Ruegg, U. T. Role of Superoxide as a signaling molecule. News Physiol. Sci. 2004, 19, 120-123.
6. Fridovich, I. Superoxide radical and superoxide dismutases. Annu. Rev. Biochem. 1995, 64, 97-112.
7. Youn, H. D.; Kim, E. J.; Roe, J. H.; Hah, Y. C.; Kang, S. O. A novel nickel-containing superoxide dismutase from Streptomyces spp. Biochem. J. 1996, 15, 889-896.
8. Beyer, W. F. Jr.; Fridovich, I. In vivo competition between iron and manganese for occupancy of the active site region of the manganese-superoxide dismutase of Escherichia coli. J. Biol. Chem. 1991, 266, 303-308.
9. Smith, M. W.; Doolittle, R. F. A comparison of evolutionary rates of the two major kinds of superoxide dismutase. J. Mol. Evol. 1992, 34, 175-184.
10. Li, Y.; Huang, T. T.; Carlson, E. J.; Melov, S.; Ursell, P. C.; Olson, J. L.; Noble, L. J.; Yoshimura, M. P.; Berger, C.; Chan, P. H.; Wallace, D. C.; Epstein, C. J. Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase. Nat. Genet. 1995, 11, 376-381.
11. Fattman, C. L.; Schaefer, L. M.; Oury, T. D. Extracellular superoxide dismutase in biology and medicine. Free Radic. Biol. Med. 2003, 35, 236-256.
12. Reveillaud, I.; Phillips, J.; Duyf, B.; Hilliker, A.; Kongpachith, A.; Fleming, J. E. Phenotypic rescue by a bovine transgene in a Cu/Zn superoxide dismutase-null mutant of Drosophila melanogaster. Mol. Cell. Biol. 1994, 14, 1302-1307.
13. Reaume, A. G.; Elliott, J. L.; Hoffman, E. K.; Kowall, N. W.; Ferrante, R. J.; Siwek, D. F.; Wilcox, H. M.; Flood, D. G.; Beal, M. F.; Brown, R. H. Jr.; Scott, R. W.; Snider, W. D. Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury. Nat. Genet. 1996, 13, 43-47.
14. Rojo, A.I.; Salinas, M.; Martin, D.; Perona, R.; Cuadrado, A. Regulation of Cu/Zn-superoxide dismutase expression via the phosphatidylinositol 3 kinase/Akt pathway and nuclear factor-kappaB. J. Neurosci. 2004, 24, 7324-7334.
15. Zimmerman, M. C.; Lazartigues, E.; Lang, J. A.; Sinnayah, P.; Ahmad, I. M.; Spitz, D. R.; Davisson, R. L. Superoxide mediates the actions of angiotensin II in the central nervous system. Circ. Res. 2002, 91, 1038-1045.
16. Huang, W. C.; Chio, C. C.; Chi, K. H.; Wu, H. M.; Lin, W. W. Superoxide anion-dependent Raf/MEK/ERK activation by peroxisome proliferator activated receptor gamma agonists 15-deoxy-delta12,14-prostaglandin J2, ciglitazone, and GW1929. Exp. Cell Res. 2002, 277, 192-200.
17. Banci, L.; Benedetto, M.; Bertini, I.; Del Conte, R.; Piccioli, M.; Viezzoli, M. S. Solution structure of reduced monomeric Q133M2 copper, zinc superoxide dismutase (SOD). Why is SOD a dimeric enzyme?. Biochemistry 1998, 37, 11780-11791.
18. Hong, Z.; LoVerde, P.T.; Thakur, A.; Hammarskjold, M.L.; Rekosh, D. Schistosoma mansoni: A Cu/Zn superoxide dismutase is glycosylated when expressed in mammalian cells and localizes to a subtegumental region in adult schistosomes. Exp. Parasitol. 1993, 76, 101-114.
19. Mei, H.; LoVerde, P. T. Schistosoma mansoni: The developmental regulation and immunolocalization of antioxidant enzymes. Exp. Parasitol. 1997, 86, 69-78.
20. Mei, H.; Hirai, H.; Tanaka, M.; Hong, Z.; Rekosh, D.; LoVerde, P. T. Schistosoma mansoni: Cloning and characterization of a gene encoding cytosolic Cu/Zn superoxide dismutase. Exp. Parasitol. 1995, 80, 250-259.
21. Kim, T. S.; Jung, Y.; Na, B. K.; Kim, K. S.; Chung, P. R. Molecular cloning and expression of Cu/Zn-containing superoxide dismutase from Fasciola hepatica. Infect. Immun. 2000, 68, 3941-3948.
22. Cardoso, R. M.; Silva, C. H.; Ulian de Araujo, A. P.; Tanaka, T.; Tanaka, M.; Garratt, R. C. Structure of the cytosolic Cu,Zn superoxide dismutase from Schistosoma mansoni. Acta Crystallogr. D. Biol. Crystallogr. 2004, 60, 569-578.
23. Shalaby, K. A.; Yin, L.; Thakur, A.; Christen, L.; Niles, E. G.; LoVerde, P.T. Protection against Schistosoma mansoni utilizing DNA vaccination with genes encoding Cu/Zn cytosolic superoxide dismutase, signal peptide-containing superoxide dismutase and glutathione peroxidase enzymes. Vaccine 2003, 22, 130-136.
24. Sanchéz-Moreno, M.; Garcia-Ruiz, M. A.; Garcia-Rejon, L.; Valero, A.; Leon, P. Superoxide dismutase in cestodes. Isocnzymatic characterization and studies of inhibition by a series of benzimidazoles and by pyrimidine derivatives of recent synthesis. Arzneimittelforschung 1989, 39, 759-761.
25. Sanchez-Moreno, M.; Leon, P.; Salas-Peregrin, J. M.; Garcia-Ruiz, M. A.; Monteoliva, M. Superoxide dismutase in trematodes. Isoenzymatic characterization and studies of inhibition by a series of benzimidazoles and by pyrimidines of recent syntheses. Arzneimittelforschung 1987, 37, 903-905.
26. Feng, J. J.; Guo, H. F.; Yao, M. Y.; Xiao, S. H. Effects of mebendazole, albendazole, and praziquantel on glutathione S-transferase and superoxide dismutase of Echinococcus granulosus cyst wall harbored in mice. Zhongguo Yao Li Xue Bao. 1995, 16, 297-300
27. Henkle-Duhrsen, K.; Kampkotter, A. Antioxidant enzyme families in parasitic nematodes. Mol. Biochem. Parasitol. 2001, 114, 129-142.
28. Li, A. H.; Kong, Y.; Cho, S. H.; Lee, H. W.; Na, B. K.; Pak, J. K.; Kim T. S. Molecular cloning and characterization of the copper/zinc and manganese superoxide dismutase genes from the human parasite Clonorchis sinensis. Parasitology 2005, 130, 687-697.
29. Leid, R. W.; Suquet, C. M. A superoxide dismutase of metacestodes of Taenia taehiaeformis. Mol. Biochem. Parasitol. 1986, 18, 301-311.
30. Gonzalez, R.; Mendoza-Hernandez, G.; Plancarte, A. Purification of Taenia solium cysticerci superoxide dismutase and myoglobin copurification. Parasitol. 2002, 88, 881-987.
31. Castellanos-Gonzalez, A, Jiménez, L.; Landa, A. Cloning, production and characterisation of a recombinant Cu/Zn superoxide dismutase from Taenia solium. Int. J. Parasitol. 2002, 32, 1175-1182.
32. Sali, S.; Blundell, T. L. Comparative protein modeling by satisfaction of spatial restraints. J. Mol. Biol. 1993, 234, 779-815.
33. Rhee, S. G.; Kang, S.W.; Chang, T. S.; Jeong, W.; Kim, K. Peroxiredoxin, a novel family of peroxidases. IUBMB Life 2001, 52, 35-41.
34. Jacobson, F. S.; Morgan, R. W.; Christman, M. F.; Ames, B. N. An alkyl hydroperoxide reductase from Salmonella typhimurium involved in the defense of DNA against oxidative damage. Purification and properties. J. Biol. Chem. 1989, 264, 1488-1496
35. Dubuisson, M.; Vander-Stricht, D.; Clippe, A.; Etienne, F.; Nauser, T.; Kissner, R.; Koppenol W. H.; Rees, J. F.; Knoops, B. Human peroxiredoxin 5 is a peroxynitrite reductase. FEBS. Lett. 2004, 571, 161-165.
36. Fujii, J.; Ikeda, Y. Advances in our understanding of peroxiredoxin, a multifunctional, mammalian redox protein. Redox. Rep. 2002, 7, 123-130.
37. Rhee, S. G.; Chae, H. Z.; Kim, K. Peroxiredoxins: A historical overview and speculative preview of novel mechanisms and emerging concepts in cell signaling. Free Radic. Biol. Med. 2005, 38, 1543-1552.
38. Wood, Z. A.; Schroder, E.; Robin-Harris, J.; Poole, L. B. Structure, mechanism and regulation of peroxiredoxins. Trends Biochem. Sci. 2003, 28, 32-40.
39. Kang, S. W.; Rhee, S. G.; Chang, T. S.; Jeong, W.; Choi, M. H. 2-Cys peroxiredoxin function in intracellular signal transduction: Therapeutic implications. Trends Mol. Med. 2005, 11, 571-578
40. Kang, S. W.; Chang, T. S.; Lee, T. H.; Kim, E. S.; Yu, D. Y.; Rhee, S. G. Cystosolic peroxiredoxin attenuates the activation of Jnk and p38 but potentiates that of Erk in Hela cells stimulated with tumor necrosis factor-alpha. J. Biol. Chem. 2004, 279, 2535-2543
41. Woo, H. A.; Kang, S. W.; Kim, H. K.; Yang, K. S.; Chae, H. Z.; Rhee, S. G. Reversible oxidation of the active site cysteine of peroxiredoxins to cysteine sulfinic acid. Immunoblot detection with antibodies specific for the hyperoxidized cysteine-containing sequence. J. Biol. Chem. 2003, 278, 47361-47364.
42. Biteau, B.; Labarre, J.; Toledano, M. B. ATP-dependent reduction of cysteine-sulphinic acid by S. cerevisiae sulphiredoxin. Nature 2003, 425, 980-984.
43. Budanov, A. V.; Sablina, A. A.; Feinstein, E.; Koonin, E. V.; Chumakov, P. M. and Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD. Science 2004, 304, 596-600.
44. Woo, H. A.; Jeong, W.; Chang, T. S.; Park, K. J.; Park, S. J.; Yang, J. S.; Rhee, S. G. Reduction of cysteine sulfinic acid by sulfiredoxin is specific to 2-cys peroxiredoxins. J. Biol. Chem. 2005, 280, 3125-3128.
45. Wood, Z. A.; Poole, L. B.; Karplus, P. A. Peroxiredoxin evolution and the regulation of hydrogen peroxide signaling. Science 2003, 300, 650-653.
46. Sayed, A- A.; Williams, D. L. Biochemical characterization of 2-Cys peroxiredoxins from Schistasoma mansani. J. Biol. Chem. 2004, 279, 26159-26166.
47. Salazar-Calderon, M.; Martin-Alonso, J. M.; Ruiz de Eguino, A. D.; Casais, R.; Marin, M. S.; Parra, F. Fasciola hepatica: heterologous expression and functional characterization of a thioredoxin peroxidase. Exp. Parasitol. 2000, 95, 63-70.
48. Molina-Lopez, J.; Jimenez, L.; Ochoa-Sanchez, A.; Landa, A. Molecular cloning and characterization of a 2-Cys peroxiredoxin from Taenia solium. J. Parasitol. 2006, 92, 796-802.
49. Salinas, G.; Fernandez, V.; Fernandez, C.; Selkirk, M. E. Echinococcus granulosus: Cloning of a thioredoxin peroxidase. Exp. Parasitol. 1998, 90, 298-301.
50. Chang, T. S.; Jeong, W.; Choi, S. Y.; Yu, S.; Kang, S. W.; Rhee, S. G. Regulation of peroxiredoxin I activity by Cdc2-mediated phosphorylation. J. Biol. Chem. 2002, 277, 25370-25776.
51. Armstrong, R. N. Structure, catalytic mechanism, and evolution of the Glutathione S-transferases. Chem. Res. Toxicol. 1997, 10, 2-18.
52. Frova, C. Glutathione transferases in the genomics era: New insights and perspectives. Biomol Eng. 2006, 23, 149-169.
53. Hayes, J. D.; Flanagan, J. U.; Jowsey, I. R. Glutathione transferases. Annu. Rev. Pharmacol. Toxicol. 2005, 45, 51-88.
54. Jakobsson, P. J.; Morgenstern, R.; Mancini, J.; Ford-Hutchinson, A.; Persson, B. Common structural features of MAPEG - a widespread superfamily of membrane associated proteins with highly divergent functions in eicosanoid and glutathione metabolism. Protein Sci. 1999, 8, 689-692.
55. Sheehan D.; Meade G.; Foley V. M.; Dowd C. A. Structure, function and evolution of glutathione transferases: Implications for classifications of non-mammalians members of an ancient enzyme superfamily. Biochem. J. 2001, 360, 1-16.
56. 2+ release channels. Int. J. Biochem. Cell Biol. 2004, 36, 1599-1612.
57. Liebau, E.; De Maria, F.; Burmeister, C.; Perbandt, M.; Turella, P.; Antonini, G.; Federici, G.; Giansanti, F.; Stella, L.; Lo Bello, M.; Caccuri, A. M.; Ricci, G. Cooperativity and Pseudo-cooperativity in the Glutathione S-Transferase from Plasmodium falciparum. J. Biol. Chem. 2005, 280, 26121-26128.
58. Salvatore, L.; Wijffels, G.; Sexton, J.; Panaccio, M.; Mailer, S.; McCauley, I.; Spithill, T. Biochemical analysis of recombinant glutathione S-transferase of Fasciola hepatica. Mol. Biochem. Parasitol. 1995, 69, 281-288.
59. Walker, J.; Crowley, P.; Moreman, A.; Barret, J. Biochemical properties of cloned glutathione S-transferase from Schistosoma mansoni and Schistosoma japonicum. Mol. Biochem. Parasitol. 1993, 61, 255-264.
60. Vibanco-Pérez N.; Jiménez L.; Merchant M. T.; Landa A. Characterization of Glutathione S-transferase of Taenia solium. J. Parasitol. 1999, 85, 448-453.
61. Vibanco-Perez, N.; Jimenez, L.; Mendoza-Hernandez, G.; Landa, A. Characterization of a recombinant mu-class glutathione S-transferase from Taenia solium. Parasitol. Res. 2002, 88, 398-404.
62. Plancarte, A.; Rendon, J. L.; Landa, A. Purification, characterization and kinetic properties of the Taenia solium glutathione S - transferase isoform 26.5 kDa. Parasitol. Res. 2004, 93, 137-144.
63. Kang, S.; Alm, I.; Park C.; Chung, Y.; Hong, S.; Kong, Y.; Cho, S.; Hong, S. Clanorchis sinensis: Molecular Cloning and Characterization of 28-kDa Glutathione S-Transferase. Exp. Parasitol. 2001, 97, 186-195.
64. Hong, S.; Lee, J.; Lee, D.; Sohn, W.; Cho, S. Molecular cloning and characterization of a mu-class glutathione S-transferase from Clonorchis sinensis. Mol. Biochem. Parasitol. 2001, 115, 69-75.