Serotonin systems upregulate the expression of hypothalamic NUCB2 via 5-HT2C receptors and induce anorexia via a leptin-independent pathway in mice

Biochemical and Biophysical Research Communications

Volumn 372, Issue 1, 2008, Pages 186-190

  Nonogaki, Katsunori ^a   Ohba, Yukie ^a   Sumii, Makiko ^a   Oka, Yoshitomo ^a  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

5 HT2C receptor; Endorphin; Food intake; Gene expression; Hypothalamus; NUCB2; Serotonin

Indexed keywords

(3 CHLOROPHENYL)PIPERAZINE; BETA ENDORPHIN; LEPTIN RECEPTOR; NUCLEOBINDIN 2; PROOPIOMELANOCORTIN; PROTEIN; SEROTONIN 2C RECEPTOR;

ANIMAL EXPERIMENT; ANOREXIA; ARTICLE; CONTROLLED STUDY; FOOD INTAKE; GENE MUTATION; HYPOTHALAMUS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; SEROTONINERGIC SYSTEM; WILD TYPE;

ANIMALS; ANOREXIA; CALCIUM-BINDING PROTEINS; DNA-BINDING PROTEINS; EATING; HYPOTHALAMUS; LEPTIN; MALE; MICE; MICE, MUTANT STRAINS; PIPERAZINES; PRO-OPIOMELANOCORTIN; RECEPTOR, SEROTONIN, 5-HT2C; RNA, MESSENGER; SEROTONIN; SEROTONIN AGONISTS; UP-REGULATION;

MUS;

EID: 44649171554     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.05.010     Document Type: Article

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