Are highly lipophilic volatile compounds expected to bioaccumulate with repeated exposures?

Toxicology Letters

Volumn 179, Issue 2, 2008, Pages 85-92

  Andersen, Melvin E ^a   Reddy, Micaela B ^b   Plotzke, Kathleen P ^c  

^a HAMNER INSTITUTES FOR HEALTH SCIENCES   (United States)

^b Department of Environmental and Radiological Health Sciences   (United States)

^c DOW CORNING CORPORATION   (United States)

Author keywords

Bioaccumulation; Decamethylcyclopentasiloxane (D5); Inhalation pharmacokinetics; Octamethylcyclotetrasiloxane (D4); PBPK modeling; Volatile compounds

Indexed keywords

DECAMETHYLCYCLOPENTASILOXANE; OCTAMETHYLCYCLOTETRASILOXANE; VOLATILE AGENT;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; CONTROLLED STUDY; EXPOSURE; HUMAN; HUMAN TISSUE; LIPOPHILICITY; MATHEMATICAL COMPUTING; NONHUMAN; PARTITION COEFFICIENT; PRIORITY JOURNAL; RAT; SIMULATION;

ANIMALS; FEMALE; HUMANS; INHALATION EXPOSURE; MALE; MODELS, BIOLOGICAL; RATS; RATS, INBRED F344; SILOXANES; TISSUE DISTRIBUTION; VOLATILIZATION;

RATTUS;

EID: 44649162440     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2008.04.007     Document Type: Article

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