-
1
-
-
0037021505
-
The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men
-
Lakka HM, Laaksonen DE, Lakka TA, et al: The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men. JAMA 2002; 288: 2709-2716.
-
(2002)
JAMA
, vol.288
, pp. 2709-2716
-
-
Lakka, H.M.1
Laaksonen, D.E.2
Lakka, T.A.3
-
2
-
-
0034837376
-
Cardiovascular morbidity and mortality associated with the metabolic syndrome
-
Isomaa B, Almgren P, Tuomi T, et al: Cardiovascular morbidity and mortality associated with the metabolic syndrome. Diabetes Care 2001; 24: 683-689.
-
(2001)
Diabetes Care
, vol.24
, pp. 683-689
-
-
Isomaa, B.1
Almgren, P.2
Tuomi, T.3
-
3
-
-
0742266631
-
The metabolic syndrome and chronic kidney disease in U.S. adults
-
Chen J, Muntner P, Hamm LL, et al: The metabolic syndrome and chronic kidney disease in U.S. adults. Ann Intern Med 2004; 140: 167-174.
-
(2004)
Ann Intern Med
, vol.140
, pp. 167-174
-
-
Chen, J.1
Muntner, P.2
Hamm, L.L.3
-
4
-
-
27444433127
-
Metabolic syndrome and the risk for chronic kidney disease among nondiabetic adults
-
Kurella M, Lo JC, Chertow GM: Metabolic syndrome and the risk for chronic kidney disease among nondiabetic adults. J Am Soc Nephrol 2005; 16: 2134-2140.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 2134-2140
-
-
Kurella, M.1
Lo, J.C.2
Chertow, G.M.3
-
5
-
-
33644638791
-
Metabolic syndrome and chronic kidney disease in Okinawa, Japan
-
Tanaka H, Shiohira Y, Uezu Y, Higa A, Iseki K: Metabolic syndrome and chronic kidney disease in Okinawa, Japan. Kidney Int 2006; 69: 369-374.
-
(2006)
Kidney Int
, vol.69
, pp. 369-374
-
-
Tanaka, H.1
Shiohira, Y.2
Uezu, Y.3
Higa, A.4
Iseki, K.5
-
6
-
-
33750741932
-
Renin-angiotensin-aldosterone system and progression of renal disease
-
Ruster C, Wolf G: Renin-angiotensin-aldosterone system and progression of renal disease. J Am Soc Nephrol 2006; 17: 2985-2991.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 2985-2991
-
-
Ruster, C.1
Wolf, G.2
-
7
-
-
33645061521
-
Evidence for renoprotection by blockade of the renin-angiotensin-aldosterone system in hypertension and diabetes
-
Karalliedde J, Viberti G: Evidence for renoprotection by blockade of the renin-angiotensin-aldosterone system in hypertension and diabetes. J Hum Hypertens 2006; 20: 239-253.
-
(2006)
J Hum Hypertens
, vol.20
, pp. 239-253
-
-
Karalliedde, J.1
Viberti, G.2
-
8
-
-
31744442785
-
Thiazolidinedione effects on blood pressure in diabetic patients with metabolic syndrome treated with glimepiride
-
Derosa G, Cicero AF, Dangelo A, et al: Thiazolidinedione effects on blood pressure in diabetic patients with metabolic syndrome treated with glimepiride. Hypertens Res 2005; 28: 917-924.
-
(2005)
Hypertens Res
, vol.28
, pp. 917-924
-
-
Derosa, G.1
Cicero, A.F.2
Dangelo, A.3
-
9
-
-
33746371464
-
Protection of the kidney by thiazolidinediones: An assessment from bench to bedside
-
Sarafidis PA, Bakris GL: Protection of the kidney by thiazolidinediones: an assessment from bench to bedside. Kidney Int 2006; 70: 1223-1233.
-
(2006)
Kidney Int
, vol.70
, pp. 1223-1233
-
-
Sarafidis, P.A.1
Bakris, G.L.2
-
10
-
-
33750736646
-
The chronic kidney disease epidemic: Stepping back and looking forward
-
Kiberd B: The chronic kidney disease epidemic: stepping back and looking forward. J Am Soc Nephrol 2006; 17: 2967-2973.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 2967-2973
-
-
Kiberd, B.1
-
11
-
-
4644221457
-
Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization
-
Go AS, Chertow GM, Fan D, McCulloch CE, Hsu CY: Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med 2004; 351: 1296-1305.
-
(2004)
N Engl J Med
, vol.351
, pp. 1296-1305
-
-
Go, A.S.1
Chertow, G.M.2
Fan, D.3
McCulloch, C.E.4
Hsu, C.Y.5
-
12
-
-
0013844370
-
Hereditary obesity in the rat associated with hyperlipemia
-
Zucker LM: Hereditary obesity in the rat associated with hyperlipemia. Ann N Y Acad Sci 1965; 131: 447-458.
-
(1965)
Ann N Y Acad Sci
, vol.131
, pp. 447-458
-
-
Zucker, L.M.1
-
13
-
-
0026512081
-
The Zucker rat model of obesity, insulin resistance, hyperlipidemia, and renal injury
-
Kasiske BL, O'Donnell MP, Keane WF: The Zucker rat model of obesity, insulin resistance, hyperlipidemia, and renal injury. Hypertension 1992; 19 (Suppl 1): I110-I115.
-
(1992)
Hypertension
, vol.19
, Issue.SUPPL. 1
-
-
Kasiske, B.L.1
O'Donnell, M.P.2
Keane, W.F.3
-
14
-
-
0022152611
-
Effects of genetic obesity on renal structure and function in the Zucker rat
-
Kasiske BL, Cleary MP, O'Donnell MP, Keane WF: Effects of genetic obesity on renal structure and function in the Zucker rat. J Lab Clin Med 1985; 106: 598-604.
-
(1985)
J Lab Clin Med
, vol.106
, pp. 598-604
-
-
Kasiske, B.L.1
Cleary, M.P.2
O'Donnell, M.P.3
Keane, W.F.4
-
15
-
-
0028888973
-
Renal hemodynamic and histological consequences of diets high in unsaturated fat, protein or sucrose in obese Zucker rats
-
Alavi FK, Zawada ET, Simmons JL: Renal hemodynamic and histological consequences of diets high in unsaturated fat, protein or sucrose in obese Zucker rats. Clin Nephrol 1995; 43: 122-130.
-
(1995)
Clin Nephrol
, vol.43
, pp. 122-130
-
-
Alavi, F.K.1
Zawada, E.T.2
Simmons, J.L.3
-
16
-
-
0036236554
-
Renoprotective effects of blockade of angiotensin II AT1 receptors in an animal model of type 2 diabetes
-
Mizuno M, Sada T, Kato M, Koike H: Renoprotective effects of blockade of angiotensin II AT1 receptors in an animal model of type 2 diabetes. Hypertens Res 2002; 25: 271-278.
-
(2002)
Hypertens Res
, vol.25
, pp. 271-278
-
-
Mizuno, M.1
Sada, T.2
Kato, M.3
Koike, H.4
-
17
-
-
0026662971
-
Renal injury in obese Zucker rats: Glomerular hemodynamic alterations and effects of enalapril
-
Schmitz PG, O'Donnell MP, Kasiske BL, Katz SA, Keane WF: Renal injury in obese Zucker rats: glomerular hemodynamic alterations and effects of enalapril. Am J Physiol 1992; 263: F496-F502.
-
(1992)
Am J Physiol
, vol.263
-
-
Schmitz, P.G.1
O'Donnell, M.P.2
Kasiske, B.L.3
Katz, S.A.4
Keane, W.F.5
-
18
-
-
0030825304
-
Antihypertensive and vasculo- and renoprotective effects of pioglitazone in genetically obese diabetic rats
-
Yoshimoto T, Naruse M, Nishikawa M, et al: Antihypertensive and vasculo- and renoprotective effects of pioglitazone in genetically obese diabetic rats. Am J Physiol 1997; 272: E989-E996.
-
(1997)
Am J Physiol
, vol.272
-
-
Yoshimoto, T.1
Naruse, M.2
Nishikawa, M.3
-
19
-
-
0031847401
-
Peroxisome proliferator-activated receptor-γ agonist, rosiglitazone, protects against nephropathy and pancreatic islet abnormalities in Zucker fatty rats
-
Buckingham RE, Al-Barazanji KA, Toseland CD, et al: Peroxisome proliferator-activated receptor-γ agonist, rosiglitazone, protects against nephropathy and pancreatic islet abnormalities in Zucker fatty rats. Diabetes 1998; 47: 1326-1334.
-
(1998)
Diabetes
, vol.47
, pp. 1326-1334
-
-
Buckingham, R.E.1
Al-Barazanji, K.A.2
Toseland, C.D.3
-
20
-
-
0345599866
-
Peroxisome proliferator-activated receptor γ agonist provides superior renal protection versus angiotensin-converting enzyme inhibition in a rat model of type 2 diabetes with obesity
-
Baylis C, Atzpodien EA, Freshour G, Engels K: Peroxisome proliferator-activated receptor γ agonist provides superior renal protection versus angiotensin-converting enzyme inhibition in a rat model of type 2 diabetes with obesity. J Pharmacol Exp Ther 2003; 307: 854-860.
-
(2003)
J Pharmacol Exp Ther
, vol.307
, pp. 854-860
-
-
Baylis, C.1
Atzpodien, E.A.2
Freshour, G.3
Engels, K.4
-
21
-
-
0027428943
-
Hypertensive rats produced by in vivo introduction of the human renin gene
-
Tomita N, Higaki J, Kaneda Y, et al: Hypertensive rats produced by in vivo introduction of the human renin gene. Circ Res 1993; 73: 898-905.
-
(1993)
Circ Res
, vol.73
, pp. 898-905
-
-
Tomita, N.1
Higaki, J.2
Kaneda, Y.3
-
22
-
-
34047228310
-
Isohumulones derived from hops ameliorate renall injury via an anti-oxidative effect in Dahl salt-sensitive rats
-
Namikoshi T, Tomita N, Fujimoto S, et al: Isohumulones derived from hops ameliorate renall injury via an anti-oxidative effect in Dahl salt-sensitive rats. Hypertens Res 2007; 30: 175-184.
-
(2007)
Hypertens Res
, vol.30
, pp. 175-184
-
-
Namikoshi, T.1
Tomita, N.2
Fujimoto, S.3
-
23
-
-
0033998369
-
Early events leading to renal injury in obese Zucker (fatty) rats with type II diabetes
-
Coimbra TM, Janssen U, Grone HJ, et al: Early events leading to renal injury in obese Zucker (fatty) rats with type II diabetes. Kidney Int 2000; 57: 167-182.
-
(2000)
Kidney Int
, vol.57
, pp. 167-182
-
-
Coimbra, T.M.1
Janssen, U.2
Grone, H.J.3
-
24
-
-
10644279910
-
Disturbances in renal autoregulation and the susceptibility to hypertension-indqced chronic kidney disease
-
Palmer BF: Disturbances in renal autoregulation and the susceptibility to hypertension-indqced chronic kidney disease. Am J Med Sci 2004; 328: 330-343.
-
(2004)
Am J Med Sci
, vol.328
, pp. 330-343
-
-
Palmer, B.F.1
-
25
-
-
0027443636
-
Pioglitazone attenuates hypertension and inhibits growth of renal arteriolar smooth muscle in rats
-
Dubey RK, Zhang HY, Reddy SR, Boegehold MA, Kotchen TA: Pioglitazone attenuates hypertension and inhibits growth of renal arteriolar smooth muscle in rats. Am J Physiol 1993; 265: R726-R732.
-
(1993)
Am J Physiol
, vol.265
-
-
Dubey, R.K.1
Zhang, H.Y.2
Reddy, S.R.3
Boegehold, M.A.4
Kotchen, T.A.5
-
26
-
-
0036918348
-
Altered renal microvascular response in Zucker obese rats
-
Hayashi K, Kanda T, Homma K, et al: Altered renal microvascular response in Zucker obese rats. Metabolism 2002; 51: 1553-1561.
-
(2002)
Metabolism
, vol.51
, pp. 1553-1561
-
-
Hayashi, K.1
Kanda, T.2
Homma, K.3
-
27
-
-
33748419495
-
Pioglitazone mitigates renal glomerular vascular changes in high-rat, high-calorie-induced type 2 diabetes mellitus
-
Rodriguez WE, Tyagi N, Joshua IG, et al: Pioglitazone mitigates renal glomerular vascular changes in high-rat, high-calorie-induced type 2 diabetes mellitus. Am J Physiol Renal Physiol 2006; 291: F694-F701.
-
(2006)
Am J Physiol Renal Physiol
, vol.291
-
-
Rodriguez, W.E.1
Tyagi, N.2
Joshua, I.G.3
-
28
-
-
0028305598
-
Antihypertensive effect of pioglitazone is not invariably associated with increased insulin sensitivity
-
Zhang HY, Reddy SR, Kotchen TA: Antihypertensive effect of pioglitazone is not invariably associated with increased insulin sensitivity. Hypertension 1994; 24: 106-110.
-
(1994)
Hypertension
, vol.24
, pp. 106-110
-
-
Zhang, H.Y.1
Reddy, S.R.2
Kotchen, T.A.3
-
29
-
-
0038177982
-
Effect of thiazolidinediones and metformin on LDL oxidation and aortic endothelium relaxation in diabetic GK rats
-
Iida KT, Kawakami Y, Suzuki M, et al: Effect of thiazolidinediones and metformin on LDL oxidation and aortic endothelium relaxation in diabetic GK rats. Am J Physiol Endocrinol Metab 2003; 284: E115-E1130.
-
(2003)
Am J Physiol Endocrinol Metab
, vol.284
-
-
Iida, K.T.1
Kawakami, Y.2
Suzuki, M.3
-
30
-
-
0346157985
-
Pioglitazone prevents hypertension and reduces oxidative stress in diet-induced obesity
-
Dobrian AD, Schriver SD, Khraibi AA, Prewitt RL: Pioglitazone prevents hypertension and reduces oxidative stress in diet-induced obesity. Hypertension 2004; 43: 48-56.
-
(2004)
Hypertension
, vol.43
, pp. 48-56
-
-
Dobrian, A.D.1
Schriver, S.D.2
Khraibi, A.A.3
Prewitt, R.L.4
-
31
-
-
0037231474
-
Peroxisome proliferator-activated receptor γ ligands increase release of nitric oxide from endothelial cells
-
Calnek DS, Mazzella L, Roser S, Roman J, Hart CM: Peroxisome proliferator-activated receptor γ ligands increase release of nitric oxide from endothelial cells. Arterioscler Thromb Vasc Biol 2003; 23: 52-57.
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 52-57
-
-
Calnek, D.S.1
Mazzella, L.2
Roser, S.3
Roman, J.4
Hart, C.M.5
-
32
-
-
1542652475
-
Nitric oxide production and regulation of endothelial nitric-oxide synthase phosphorylation by prolonged treatment with troglitazone: Evidence for involvement of peroxisome proliferator-activated receptor (PPAR) γ-dependent and PPARγ-independent signaling pathways
-
Cho DH, Choi YJ, Jo SA, Jo I: Nitric oxide production and regulation of endothelial nitric-oxide synthase phosphorylation by prolonged treatment with troglitazone: evidence for involvement of peroxisome proliferator-activated receptor (PPAR) γ-dependent and PPARγ-independent signaling pathways. J Biol Chem 2004; 279: 2499-2506.
-
(2004)
J Biol Chem
, vol.279
, pp. 2499-2506
-
-
Cho, D.H.1
Choi, Y.J.2
Jo, S.A.3
Jo, I.4
-
33
-
-
20444477924
-
Pioglitazone lowers systemic asymmetric dimethylarginine by inducing dimethylarginine dimethylamino-hydrolase in rats
-
Wakino S, Hayashi K, Tatematsu S, et al: Pioglitazone lowers systemic asymmetric dimethylarginine by inducing dimethylarginine dimethylamino-hydrolase in rats. Hypertens Res 2005; 28: 255-262.
-
(2005)
Hypertens Res
, vol.28
, pp. 255-262
-
-
Wakino, S.1
Hayashi, K.2
Tatematsu, S.3
-
34
-
-
0036154243
-
Biphasic vasodilator action of troglitazone on the renal microcirculation
-
Arima S, Kohagura K, Takeuchi K, et al: Biphasic vasodilator action of troglitazone on the renal microcirculation. J Am Soc Nephrol 2002; 13: 342-349.
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 342-349
-
-
Arima, S.1
Kohagura, K.2
Takeuchi, K.3
-
35
-
-
17644375558
-
Upregulation of angiotensin IItype I receptor, inflammatory mediators, and enzymes of arachidonate metabolism in obese Zucker rat kidney: Reversal by angiotensin II type I receptor blockade
-
Xu ZG, Lanting L, Vaziri ND, et al: Upregulation of angiotensin IItype I receptor, inflammatory mediators, and enzymes of arachidonate metabolism in obese Zucker rat kidney: reversal by angiotensin II type I receptor blockade. Circulation 2005; 111: 1962-1969.
-
(2005)
Circulation
, vol.111
, pp. 1962-1969
-
-
Xu, Z.G.1
Lanting, L.2
Vaziri, N.D.3
-
36
-
-
0037076294
-
Structure, endothelial function, cell growth, and inflammation in blood vessels of angiotensin II-infused rats: Role of peroxisome proliferator-activated receptor-γ
-
Diep QN, El Mabrouk M, Cohn JS, et al: Structure, endothelial function, cell growth, and inflammation in blood vessels of angiotensin II-infused rats: role of peroxisome proliferator-activated receptor-γ. Circulation 2002; 105: 2296-2302.
-
(2002)
Circulation
, vol.105
, pp. 2296-2302
-
-
Diep, Q.N.1
El Mabrouk, M.2
Cohn, J.S.3
-
37
-
-
20044362239
-
From the periphery of the glomerular capillary wall toward the center of disease: Podocyte injury comes of age in diabetic nephropathy
-
Wolf G, Chen S, Ziyadeh FN: From the periphery of the glomerular capillary wall toward the center of disease: podocyte injury comes of age in diabetic nephropathy. Diabetes 2005; 54: 1626-1634.
-
(2005)
Diabetes
, vol.54
, pp. 1626-1634
-
-
Wolf, G.1
Chen, S.2
Ziyadeh, F.N.3
-
38
-
-
33646939809
-
Transcriptional regulation of nephrin gene by peroxisome proliferator-activated receptor-γ agonist: Molecular mechanism of the antiproteinuric effect of pioglitazone
-
Benigni A, Zoja C, Tomasoni S, et al: Transcriptional regulation of nephrin gene by peroxisome proliferator-activated receptor-γ agonist: molecular mechanism of the antiproteinuric effect of pioglitazone. J Am Soc Nephrol 2006; 17: 1624-1632.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 1624-1632
-
-
Benigni, A.1
Zoja, C.2
Tomasoni, S.3
-
39
-
-
33750736645
-
How does proteinuria cause progressive renal damage?
-
Abbate M, Zoja C, Remuzzi G: How does proteinuria cause progressive renal damage? J Am Soc Nephrol 2006; 17: 2974-2984.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 2974-2984
-
-
Abbate, M.1
Zoja, C.2
Remuzzi, G.3
-
40
-
-
0035046542
-
Peroxisome proliferator-activated receptor-γ agonist troglitazone protects against nondiabetic glomerulosclerosis in rats
-
Ma LJ, Marcantoni C, Linton MF, Fazio S, Fogo AB: Peroxisome proliferator-activated receptor-γ agonist troglitazone protects against nondiabetic glomerulosclerosis in rats. Kidney Int 2001; 59: 1899-1910.
-
(2001)
Kidney Int
, vol.59
, pp. 1899-1910
-
-
Ma, L.J.1
Marcantoni, C.2
Linton, M.F.3
Fazio, S.4
Fogo, A.B.5
-
41
-
-
20544469044
-
Pioglitazone inhibits cell growth and reduces matrix production in human kidney fibroblasts
-
Zafiriou S, Stanners SR, Saad S, Polhill TS, Poronnik P, Pollock CA: Pioglitazone inhibits cell growth and reduces matrix production in human kidney fibroblasts. J Am Soc Nephrol 2005; 16: 638-645.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 638-645
-
-
Zafiriou, S.1
Stanners, S.R.2
Saad, S.3
Polhill, T.S.4
Poronnik, P.5
Pollock, C.A.6
-
42
-
-
33645454825
-
Hepatocyte growth factor is a downstream effector that mediates the antifibrotic action of peroxisome proliferator-activated receptor-γ agonists
-
Li Y, Wen X, Spataro BC, Hu K, Dai C, Liu Y: Hepatocyte growth factor is a downstream effector that mediates the antifibrotic action of peroxisome proliferator-activated receptor-γ agonists. J Am Soc Nephrol 2006; 17: 54-65.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 54-65
-
-
Li, Y.1
Wen, X.2
Spataro, B.C.3
Hu, K.4
Dai, C.5
Liu, Y.6
-
43
-
-
0034711678
-
Modulation of vascular inflammation in vitro and in vivo by peroxisome proliferator-activated receptor-γ activators
-
Pasceri V, Wu HD, Willerson JT, Yeh ET: Modulation of vascular inflammation in vitro and in vivo by peroxisome proliferator-activated receptor-γ activators. Circulation 2000; 101: 235-238.
-
(2000)
Circulation
, vol.101
, pp. 235-238
-
-
Pasceri, V.1
Wu, H.D.2
Willerson, J.T.3
Yeh, E.T.4
-
44
-
-
0036842574
-
Antiinflammatory and antiarteriosclerotic effects of pioglitazone
-
Ishibashi M, Egashira K, Hiasa K, et al: Antiinflammatory and antiarteriosclerotic effects of pioglitazone. Hypertension 2002; 40: 687-693.
-
(2002)
Hypertension
, vol.40
, pp. 687-693
-
-
Ishibashi, M.1
Egashira, K.2
Hiasa, K.3
-
45
-
-
34547887314
-
Pioglitazone ameliorates endothelial dysfunction in obese rats with nephropathy
-
Namikoshi T, Satoh M, Tomita N, et al: Pioglitazone ameliorates endothelial dysfunction in obese rats with nephropathy. Biochem Biophys Res Commun 2007; 361: 835-840.
-
(2007)
Biochem Biophys Res Commun
, vol.361
, pp. 835-840
-
-
Namikoshi, T.1
Satoh, M.2
Tomita, N.3
|