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Volumn 38, Issue 7, 2008, Pages 704-716

HCV selection and HVR1 evolution in a chimpanzee chronically infected with HCV-1 over 12 years

Author keywords

Chimpanzee; HCV; HVR1; Quasi species; Sequencing

Indexed keywords

ACUTE HEPATITIS; AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHIMPANZEE; CONSENSUS SEQUENCE; CONSERVATION GENETICS; GENE STRUCTURE; GENETIC SELECTION; HEPATITIS C; HEPATITIS C VIRUS; HEPATITIS C VIRUS 1; INOCULATION; MOLECULAR EVOLUTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; UNINDEXED SEQUENCE; VIRAL GENETICS; VIRUS LOAD; VIRUS STRAIN; VIRUS TRANSMISSION;

EID: 44649155139     PISSN: 13866346     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1872-034X.2008.00320.x     Document Type: Article
Times cited : (15)

References (56)
  • 1
    • 0028348687 scopus 로고
    • Transmission of hepatitis C virus - Route, dose, and titer
    • Alter M. Transmission of hepatitis C virus - route, dose, and titer. N Engl J Med 1994; 330: 784-6.
    • (1994) N Engl J Med , vol.330 , pp. 784-786
    • Alter, M.1
  • 2
    • 0024509701 scopus 로고
    • Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome
    • Choo Q, Kuo G, Weiner A etal. Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. Science 1989; 244: 359-62.
    • (1989) Science , vol.244 , pp. 359-362
    • Choo, Q.1    Kuo, G.2    Weiner, A.3
  • 3
    • 0033932001 scopus 로고    scopus 로고
    • Recovery, persistence, and sequelae in hepatitis C virus infection: A perspective on long-term outcome
    • Alter H, Seeff L. Recovery, persistence, and sequelae in hepatitis C virus infection: A perspective on long-term outcome. Semin Liver Dis 2000; 20: 17-35.
    • (2000) Semin Liver Dis , vol.20 , pp. 17-35
    • Alter, H.1    Seeff, L.2
  • 4
    • 0030955346 scopus 로고    scopus 로고
    • Epidemiology of hepatitis C
    • Alter M. Epidemiology of hepatitis C. Hepatology 1997; 26: 62S-5S.
    • (1997) Hepatology , vol.26
    • Alter, M.1
  • 5
    • 34248182626 scopus 로고    scopus 로고
    • Complete genomic sequences for hepatitis C virus subtypes 6f, 6i, 6j, and 6m isolated from five Thai blood donors and two infected spouses with inference to sexual transmission
    • Lu L, Li C, Fu Y et al. Complete genomic sequences for hepatitis C virus subtypes 6f, 6i, 6j, and 6m isolated from five Thai blood donors and two infected spouses with inference to sexual transmission. J Gen Virol 2007; 88: 1505-18.
    • (2007) J Gen Virol , vol.88 , pp. 1505-1518
    • Lu, L.1    Li, C.2    Fu, Y.3
  • 6
    • 0034646996 scopus 로고    scopus 로고
    • The outcome of acute hepatitis C predicted by the evolution of the viral quasispecies
    • Farci P, Shimoda A, Coiana A et al. The outcome of acute hepatitis C predicted by the evolution of the viral quasispecies. Science 2000; 228: 339-44.
    • (2000) Science , vol.228 , pp. 339-344
    • Farci, P.1    Shimoda, A.2    Coiana, A.3
  • 7
    • 15244353559 scopus 로고    scopus 로고
    • Wide range of quasispecies diversity during primary hepatitis C virus infection
    • Herring B, Tsui R, Peddada L et al. Wide range of quasispecies diversity during primary hepatitis C virus infection. J Virol 2005; 79: 4340-6.
    • (2005) J Virol , vol.79 , pp. 4340-4346
    • Herring, B.1    Tsui, R.2    Peddada, L.3
  • 8
    • 0034916434 scopus 로고    scopus 로고
    • Occurrence of identical hypervariable region 1 sequences of hepatitis C virus in transfusion recipients and their respective blood donors: Divergence over time
    • Lin H, Seeff L, Barbosa L etal. Occurrence of identical hypervariable region 1 sequences of hepatitis C virus in transfusion recipients and their respective blood donors: Divergence over time. Hepatology 2001; 34: 424-9.
    • (2001) Hepatology , vol.34 , pp. 424-429
    • Lin, H.1    Seeff, L.2    Barbosa, L.3
  • 9
    • 0031749172 scopus 로고    scopus 로고
    • Evolution of hypervariable region 1 of hepatitis C virus in primary infection
    • Manzin A, Solforosi L, Petrelli E etal. Evolution of hypervariable region 1 of hepatitis C virus in primary infection. J Virol 1998; 72: 6271-6.
    • (1998) J Virol , vol.72 , pp. 6271-6276
    • Manzin, A.1    Solforosi, L.2    Petrelli, E.3
  • 10
    • 9644276894 scopus 로고    scopus 로고
    • Mode of HCV infection examined by polymorphism of hypervariable region-1 in cases of acute hepatitis C after accidental exposure to blood-borne pathogens
    • Takeda T, Tatsumi N, Nakayama Y etal. Mode of HCV infection examined by polymorphism of hypervariable region-1 in cases of acute hepatitis C after accidental exposure to blood-borne pathogens. J Med Virol 2005; 75: 35-41.
    • (2005) J Med Virol , vol.75 , pp. 35-41
    • Takeda, T.1    Tatsumi, N.2    Nakayama, Y.3
  • 11
  • 12
    • 0031783128 scopus 로고    scopus 로고
    • Hepatitis C virus infection: Virus/host interactions
    • Pawlotsky J. Hepatitis C virus infection: Virus/host interactions. J Viral Hepat 1998; 5 (Suppl 1): 3-8.
    • (1998) J Viral Hepat , vol.5 , Issue.SUPPL. 1 , pp. 3-8
    • Pawlotsky, J.1
  • 13
    • 0026021431 scopus 로고
    • Hypervariable regions in the putative glycoprotein of hepatitis C virus
    • Hijikata M, Kato N, Ootsuyama Y et al. Hypervariable regions in the putative glycoprotein of hepatitis C virus. Biochem Biophys Res Commun 1991; 175: 220-8.
    • (1991) Biochem Biophys Res Commun , vol.175 , pp. 220-228
    • Hijikata, M.1    Kato, N.2    Ootsuyama, Y.3
  • 14
    • 0026025737 scopus 로고
    • Variable and hypervariable domains are found in the regions of HCV corresponding to the flavivirus envelope and NS1 proteins and the pestivirus envelope glycoproteins
    • Weiner A, Brauer M, Rosenblatt J et al. Variable and hypervariable domains are found in the regions of HCV corresponding to the flavivirus envelope and NS1 proteins and the pestivirus envelope glycoproteins. Virology 1991; 180: 842-8.
    • (1991) Virology , vol.180 , pp. 842-948
    • Weiner, A.1    Brauer, M.2    Rosenblatt, J.3
  • 15
    • 0028945033 scopus 로고
    • Genetic heterogeneity of hepatitis C virus: Quasispecies and genotype
    • Bukh J, Miller R, Purcell R. Genetic heterogeneity of hepatitis C virus: quasispecies and genotype. Semin Liver Dis 1995; 15: 41-63.
    • (1995) Semin Liver Dis , vol.15 , pp. 41-63
    • Bukh, J.1    Miller, R.2    Purcell, R.3
  • 16
    • 0030773306 scopus 로고    scopus 로고
    • The quasispecies of hepatitis C virus and the host immune response
    • Farci P, Bukh J, Purcell R. The quasispecies of hepatitis C virus and the host immune response. Springer Semin Immunopathol 1997; 19: 5-26.
    • (1997) Springer Semin Immunopathol , vol.19 , pp. 5-26
    • Farci, P.1    Bukh, J.2    Purcell, R.3
  • 17
    • 0032862444 scopus 로고    scopus 로고
    • Quasispecies in viral persistence and pathogenesis of hepatitis C virus
    • Forns X, Purcell R, Bukh J. Quasispecies in viral persistence and pathogenesis of hepatitis C virus. Trends Microbiol 1999; 7: 402-10.
    • (1999) Trends Microbiol , vol.7 , pp. 402-410
    • Forns, X.1    Purcell, R.2    Bukh, J.3
  • 18
    • 0032809666 scopus 로고    scopus 로고
    • Evolution of the hypervariable region of hepatitis C virus
    • Smith D. Evolution of the hypervariable region of hepatitis C virus. J Viral Hepat 1999; 6 (Suppl 1): 41-6.
    • (1999) J Viral Hepat , vol.6 , Issue.SUPPL. 1 , pp. 41-46
    • Smith, D.1
  • 19
    • 0028912912 scopus 로고
    • CTL responses of HLA-A2.1-transgenic mice specific for hepatitis C viral peptides predict epitopes for CTL of humans carrying HLA-A2.1
    • Shirai M, Arichi T, Nishioka M etal. CTL responses of HLA-A2.1-transgenic mice specific for hepatitis C viral peptides predict epitopes for CTL of humans carrying HLA-A2.1. J Immunol 1995; 154: 2733-42.
    • (1995) J Immunol , vol.154 , pp. 2733-2742
    • Shirai, M.1    Arichi, T.2    Nishioka, M.3
  • 20
    • 0027223705 scopus 로고
    • Humoral immune response to hypervariable region 1 of the putative envelope glycoprotein (gp70) of hepatitis C virus
    • Kato N, Sekiya H, Ootsuyama Y etal. Humoral immune response to hypervariable region 1 of the putative envelope glycoprotein (gp70) of hepatitis C virus. J Virol 1993; 67: 3923-30.
    • (1993) J Virol , vol.67 , pp. 3923-3930
    • Kato, N.1    Sekiya, H.2    Ootsuyama, Y.3
  • 21
    • 0026568641 scopus 로고
    • Evidence for immune selection of hepatitis C virus (HCV) putative envelope glycoprotein variants: Potential role in chronic HCV infections
    • Weiner A, Geysen H, Christopherson C etal. Evidence for immune selection of hepatitis C virus (HCV) putative envelope glycoprotein variants: potential role in chronic HCV infections. Proc Natl Acad Sci USA 1992; 89: 3468-72.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 3468-3472
    • Weiner, A.1    Geysen, H.2    Christopherson, C.3
  • 22
    • 0028087985 scopus 로고
    • Prevention of hepatitis C virus infection in chimpanzees after antibody-mediated in vitro neutralization
    • Farci P, Alter H, Wong D etal. Prevention of hepatitis C virus infection in chimpanzees after antibody-mediated in vitro neutralization. Proc Natl Acad Sci USA 1994; 91: 7792-6.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 7792-7796
    • Farci, P.1    Alter, H.2    Wong, D.3
  • 23
    • 12644289313 scopus 로고    scopus 로고
    • Prevention of hepatitis C virus infection in chimpanzees by hyperimmune serum against the hypervariable region 1 of the envelope 2 protein
    • Farci P, Shimoda A, Wong D etal. Prevention of hepatitis C virus infection in chimpanzees by hyperimmune serum against the hypervariable region 1 of the envelope 2 protein. Proc Natl Acad Sci USA 1996; 93: 15394-9.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 15394-15399
    • Farci, P.1    Shimoda, A.2    Wong, D.3
  • 24
    • 0030587469 scopus 로고    scopus 로고
    • A hyperimmune serum against a synthetic peptide corresponding to the hypervariable region 1 of hepatitis C virus can prevent viral infection in cell cultures
    • Shimizu Y, Igarashi H, Kiyohara T et al. A hyperimmune serum against a synthetic peptide corresponding to the hypervariable region 1 of hepatitis C virus can prevent viral infection in cell cultures. Virology 1996; 223: 409-12.
    • (1996) Virology , vol.223 , pp. 409-412
    • Shimizu, Y.1    Igarashi, H.2    Kiyohara, T.3
  • 25
    • 0028140138 scopus 로고
    • Neutralizing antibodies against hepatitis C virus and the emergence of neutralization escape mutant viruses
    • Shimizu Y, Hijikata M, Iwamoto A etal. Neutralizing antibodies against hepatitis C virus and the emergence of neutralization escape mutant viruses. J Virol 1994; 68: 1494-500.
    • (1994) J Virol , vol.68 , pp. 1494-1500
    • Shimizu, Y.1    Hijikata, M.2    Iwamoto, A.3
  • 26
    • 0027369206 scopus 로고
    • Dynamics of genome change in the E2/NS1 region of hepatitis C virus in vivo
    • Higashi Y, Kakumu S, Yoshioka K et al. Dynamics of genome change in the E2/NS1 region of hepatitis C virus in vivo. Virology 1993; 197: 659-68.
    • (1993) Virology , vol.197 , pp. 659-668
    • Higashi, Y.1    Kakumu, S.2    Yoshioka, K.3
  • 27
    • 0032976214 scopus 로고    scopus 로고
    • Acute hepatitis C virus structural gene sequences as predictors of persistent viremia: Hypervariable region 1 as a decoy
    • Ray S, Wang Y, Laeyendecker O etal. Acute hepatitis C virus structural gene sequences as predictors of persistent viremia: Hypervariable region 1 as a decoy. J Virol 1999; 73: 2938-46.
    • (1999) J Virol , vol.73 , pp. 2938-2946
    • Ray, S.1    Wang, Y.2    Laeyendecker, O.3
  • 28
    • 0028870181 scopus 로고
    • Sequence evolution of the hypervariable region in the putative envelope region E2/NS1 of hepatitis C virus is correlated with specific humoral immune responses
    • van Doorn L, Capriles I, Maertens G etal. Sequence evolution of the hypervariable region in the putative envelope region E2/NS1 of hepatitis C virus is correlated with specific humoral immune responses. J Virol 1995; 69: 773-8.
    • (1995) J Virol , vol.69 , pp. 773-778
    • van Doorn, L.1    Capriles, I.2    Maertens, G.3
  • 29
    • 0033033612 scopus 로고    scopus 로고
    • Variation of hepatitis C virus following serial transmission: Multiple mechanisms of diversification of the hypervariable region and evidence for convergent genome evolution
    • Casino C, McAllister J, Davidson F etal. Variation of hepatitis C virus following serial transmission: Multiple mechanisms of diversification of the hypervariable region and evidence for convergent genome evolution. J Gen Virol 1999; 80: 717-25.
    • (1999) J Gen Virol , vol.80 , pp. 717-725
    • Casino, C.1    McAllister, J.2    Davidson, F.3
  • 30
    • 0036021187 scopus 로고    scopus 로고
    • Drift in the hypervariable region of the hepatitis C virus during 27 years in two patients
    • Gao G, Buskell Z, Seeff L etal. Drift in the hypervariable region of the hepatitis C virus during 27 years in two patients. J Med Virol 2002; 68: 60-7.
    • (2002) J Med Virol , vol.68 , pp. 60-67
    • Gao, G.1    Buskell, Z.2    Seeff, L.3
  • 31
    • 0031901336 scopus 로고    scopus 로고
    • Long-term evolution of the hypervariable region of hepatitis C virus in a common-source-infected cohort
    • McAllister J, Casino C, Davidson F etal. Long-term evolution of the hypervariable region of hepatitis C virus in a common-source-infected cohort. J Virol 1998; 72: 4893-905.
    • (1998) J Virol , vol.72 , pp. 4893-4905
    • McAllister, J.1    Casino, C.2    Davidson, F.3
  • 32
    • 0031925283 scopus 로고    scopus 로고
    • Analysis of hepatitis C virus-inoculated chimpanzees reveals unexpected clinical profiles
    • Bassett S, Brasky K, Lanford R. Analysis of hepatitis C virus-inoculated chimpanzees reveals unexpected clinical profiles. J Virol 1998; 72: 2589-99.
    • (1998) J Virol , vol.72 , pp. 2589-2599
    • Bassett, S.1    Brasky, K.2    Lanford, R.3
  • 33
    • 0032923618 scopus 로고    scopus 로고
    • Viral persistence, antibody to E1 and E2, and hypervariable region 1 sequence stability in hepatitis C virus-inoculated chimpanzees
    • Bassett S, Thomas D, Brasky K etal. Viral persistence, antibody to E1 and E2, and hypervariable region 1 sequence stability in hepatitis C virus-inoculated chimpanzees. J Virol 1999; 73: 1118-26.
    • (1999) J Virol , vol.73 , pp. 1118-1126
    • Bassett, S.1    Thomas, D.2    Brasky, K.3
  • 34
    • 0034011434 scopus 로고    scopus 로고
    • Hypervariable region 1 sequence stability during hepatitis C virus replication in chimpanzees
    • Ray S, Mao Q, Lanford R etal. Hypervariable region 1 sequence stability during hepatitis C virus replication in chimpanzees. J Virol 2000; 74: 3058-66.
    • (2000) J Virol , vol.74 , pp. 3058-3066
    • Ray, S.1    Mao, Q.2    Lanford, R.3
  • 35
    • 0030864915 scopus 로고    scopus 로고
    • Transmission of hepatitis C by intrahepatic inoculation with transcribed RNA
    • Kolykhalov A, Agapov E, Blight K etal. Transmission of hepatitis C by intrahepatic inoculation with transcribed RNA. Science 1997; 277: 570-4.
    • (1997) Science , vol.277 , pp. 570-574
    • Kolykhalov, A.1    Agapov, E.2    Blight, K.3
  • 36
    • 0033020469 scopus 로고    scopus 로고
    • Long-term follow-up of chimpanzees inoculated with the first infectious clone for hepatitis C virus
    • Major M, Mihalik K, Fernandez J etal. Long-term follow-up of chimpanzees inoculated with the first infectious clone for hepatitis C virus. J Virol 1999; 73: 3317-25.
    • (1999) J Virol , vol.73 , pp. 3317-3325
    • Major, M.1    Mihalik, K.2    Fernandez, J.3
  • 37
    • 0025010980 scopus 로고
    • Parenterally transmitted non-A, non-B hepatitis: Virus-specific antibody response patterns in hepatitis C virus-infected chimpanzees
    • Bradley D, Krawczynski K, Ebert J et al. Parenterally transmitted non-A, non-B hepatitis: Virus-specific antibody response patterns in hepatitis C virus-infected chimpanzees. Gastroenterology 1990; 99: 1054-60.
    • (1990) Gastroenterology , vol.99 , pp. 1054-1060
    • Bradley, D.1    Krawczynski, K.2    Ebert, J.3
  • 38
    • 30344441223 scopus 로고    scopus 로고
    • Selective transmission of hepatitis C virus genotypes and quasispecies in humans and experimentally infected chimpanzees
    • Nainan O, Lu L, Gao F et al. Selective transmission of hepatitis C virus genotypes and quasispecies in humans and experimentally infected chimpanzees. J Gen Virol 2006; 87: 83-91.
    • (2006) J Gen Virol , vol.87 , pp. 83-91
    • Nainan, O.1    Lu, L.2    Gao, F.3
  • 39
    • 0018396619 scopus 로고
    • Experimental infection of chimpanzees with antihemophilic (factor VIII) materials: Recovery of virus-like particles associated with non-A, non-B hepatitis
    • Bradley D, Cook E, Maynard J et al. Experimental infection of chimpanzees with antihemophilic (factor VIII) materials: Recovery of virus-like particles associated with non-A, non-B hepatitis. J Med Virol 1979; 3: 253-69.
    • (1979) J Med Virol , vol.3 , pp. 253-269
    • Bradley, D.1    Cook, E.2    Maynard, J.3
  • 40
    • 0035127362 scopus 로고    scopus 로고
    • Evaluation of accumulation of hepatitis C virus mutations in a chronically infected chimpanzee: Comparison of the core, E1, HVR1, and NS5b regions
    • Lu L, Nakano T, Orito E etal. Evaluation of accumulation of hepatitis C virus mutations in a chronically infected chimpanzee: Comparison of the core, E1, HVR1, and NS5b regions. J Virol 2001; 75: 3004-9.
    • (2001) J Virol , vol.75 , pp. 3004-3009
    • Lu, L.1    Nakano, T.2    Orito, E.3
  • 41
    • 0345355151 scopus 로고    scopus 로고
    • High-throughput real-time reverse transcription-PCR quantitation of hepatitis C virus RNA
    • Martell M, Gomez J, Esteban J etal. High-throughput real-time reverse transcription-PCR quantitation of hepatitis C virus RNA. J Clin Microbiol 1999; 37: 327-32.
    • (1999) J Clin Microbiol , vol.37 , pp. 327-332
    • Martell, M.1    Gomez, J.2    Esteban, J.3
  • 42
    • 0025678383 scopus 로고
    • Molecular clock of viral evolution, and the neutral theory
    • Gojobori T, Moriyama E, Kimura M. Molecular clock of viral evolution, and the neutral theory. Proc Natl Acad Sci USA 1990; 87: 10015-18.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 10015-10018
    • Gojobori, T.1    Moriyama, E.2    Kimura, M.3
  • 43
    • 0028941695 scopus 로고
    • Heterogeneity of hepatitis C virus genotypes in hemophilia: Relationship with chronic liver disease
    • Preston F, Jarvis L, Makris M etal. Heterogeneity of hepatitis C virus genotypes in hemophilia: Relationship with chronic liver disease. Blood 1995; 85: 1259-62.
    • (1995) Blood , vol.85 , pp. 1259-1262
    • Preston, F.1    Jarvis, L.2    Makris, M.3
  • 44
    • 0036096392 scopus 로고    scopus 로고
    • Update on chronic hepatitis C in hemophiliacs
    • Franchini M, Capra F, Tagliaferri A et al. Update on chronic hepatitis C in hemophiliacs. Haematologica 2002; 87: 542-9.
    • (2002) Haematologica , vol.87 , pp. 542-549
    • Franchini, M.1    Capra, F.2    Tagliaferri, A.3
  • 45
    • 0033378309 scopus 로고    scopus 로고
    • Hepatitis C virus and human immunodeficiency virus: Clinical issues in coinfection
    • Dieterich D. Hepatitis C virus and human immunodeficiency virus: clinical issues in coinfection. Am J Med 1999; 107: 79S-84S.
    • (1999) Am J Med , vol.107
    • Dieterich, D.1
  • 46
    • 0031026417 scopus 로고    scopus 로고
    • The association between hepatitis C virus genotype and human immunodeficiency virus disease progression in a cohort of hemophilic men
    • Sabin C, Telfer P, Phillips A et al. The association between hepatitis C virus genotype and human immunodeficiency virus disease progression in a cohort of hemophilic men. J Infect Dis 1997; 175: 164-8.
    • (1997) J Infect Dis , vol.175 , pp. 164-168
    • Sabin, C.1    Telfer, P.2    Phillips, A.3
  • 47
    • 0027441925 scopus 로고
    • The pathology of hepatitis C as a function of mode of transmission: Blood transfusion vs. intravenous drug use
    • Gordon S, Elloway R, Long J etal. The pathology of hepatitis C as a function of mode of transmission: Blood transfusion vs. intravenous drug use. Hepatology 1993; 18: 1338-43.
    • (1993) Hepatology , vol.18 , pp. 1338-1343
    • Gordon, S.1    Elloway, R.2    Long, J.3
  • 48
    • 0027959912 scopus 로고
    • Superinfection of chimpanzees carrying hepatitis C virus of genotype II/ 1b with that of genotype III/2a or I/1a
    • Okamoto H, Mishiro S, Tokita H etal. Superinfection of chimpanzees carrying hepatitis C virus of genotype II/1b with that of genotype III/ 2a or I/1a. Hepatology 1994; 20: 1131-6.
    • (1994) Hepatology , vol.20 , pp. 1131-1136
    • Okamoto, H.1    Mishiro, S.2    Tokita, H.3
  • 49
    • 0038122779 scopus 로고    scopus 로고
    • Liver transplantation with hepatitis C virus-infected graft: Interaction between donor and recipient viral strains
    • Fan X, Lang D, Xu Y etal. Liver transplantation with hepatitis C virus-infected graft: Interaction between donor and recipient viral strains. Hepatology 2003; 38: 25-33.
    • (2003) Hepatology , vol.38 , pp. 25-33
    • Fan, X.1    Lang, D.2    Xu, Y.3
  • 50
    • 0036137799 scopus 로고    scopus 로고
    • Search for hepatitis C virus negative-strand RNA sequences and analysis of viral sequences in the central nervous system: Evidence of replication
    • Radkowski M, Wilkinson J, Nowicki M etal. Search for hepatitis C virus negative-strand RNA sequences and analysis of viral sequences in the central nervous system: Evidence of replication. J Virol 2002; 76: 600-8.
    • (2002) J Virol , vol.76 , pp. 600-608
    • Radkowski, M.1    Wilkinson, J.2    Nowicki, M.3
  • 51
    • 0031947488 scopus 로고    scopus 로고
    • Predominance of HCV type 2a in saliva from intravenous drug users
    • Roy K, Bagg J, McCarron B et al. Predominance of HCV type 2a in saliva from intravenous drug users. J Med Virol 1998; 54: 271-5.
    • (1998) J Med Virol , vol.54 , pp. 271-275
    • Roy, K.1    Bagg, J.2    McCarron, B.3
  • 52
    • 18144379843 scopus 로고    scopus 로고
    • Compartmentalization of hepatitis C virus genotypes between plasma and peripheral blood mononuclear cells
    • Roque-Afonso A, Ducoulombier D, Di Liberto G et al. Compartmentalization of hepatitis C virus genotypes between plasma and peripheral blood mononuclear cells. J Virol 2005; 79: 6349-57.
    • (2005) J Virol , vol.79 , pp. 6349-6357
    • Roque-Afonso, A.1    Ducoulombier, D.2    Di Liberto, G.3
  • 53
    • 0031936597 scopus 로고    scopus 로고
    • Immunity in chimpanzees chronically infected with hepatitis C virus: Role of minor quasispecies in reinfection
    • Wyatt C, Andrus L, Brotman B et al. Immunity in chimpanzees chronically infected with hepatitis C virus: Role of minor quasispecies in reinfection. J Virol 1998; 72: 1725-30.
    • (1998) J Virol , vol.72 , pp. 1725-1730
    • Wyatt, C.1    Andrus, L.2    Brotman, B.3
  • 54
    • 0027225677 scopus 로고
    • Superinfection of heterologous hepatitis C virus in a patient with chronic type C hepatitis
    • Kao J, Chen P, Lai M et al. Superinfection of heterologous hepatitis C virus in a patient with chronic type C hepatitis. Gastroenterology 1993; 105: 583-7.
    • (1993) Gastroenterology , vol.105 , pp. 583-587
    • Kao, J.1    Chen, P.2    Lai, M.3
  • 55
    • 33745763869 scopus 로고    scopus 로고
    • Clinical and therapeutic implications of hepatitis C virus compartmentalization
    • Di Liberto G, Roque-Afonso A, Kara R etal. Clinical and therapeutic implications of hepatitis C virus compartmentalization. Gastroenterology 2006; 131: 76-84.
    • (2006) Gastroenterology , vol.131 , pp. 76-84
    • Di Liberto, G.1    Roque-Afonso, A.2    Kara, R.3
  • 56
    • 22344447485 scopus 로고    scopus 로고
    • Divergent and convergent evolution after a common-source outbreak of hepatitis C virus
    • Ray S, Fanning L, Wang X etal. Divergent and convergent evolution after a common-source outbreak of hepatitis C virus. J Exp Med 2005; 201: 1753-9.
    • (2005) J Exp Med , vol.201 , pp. 1753-1759
    • Ray, S.1    Fanning, L.2    Wang, X.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.