메뉴 건너뛰기




Volumn 6, Issue SUPPL. 1, 1999, Pages 41-46

Evolution of the hypervariable region of hepatitis C virus

Author keywords

Evolution; Function; Hepatitis C virus; Hypervariable region; Persistence

Indexed keywords

VIRUS PROTEIN;

EID: 0032809666     PISSN: 13520504     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2893.1999.00010.x     Document Type: Article
Times cited : (40)

References (51)
  • 1
    • 0026334457 scopus 로고
    • Nucleotide sequence and mutation rate of the H strain of hepatitis C virus
    • Ogata N, Alter HJ, Miller RH, Purcell RH. Nucleotide sequence and mutation rate of the H strain of hepatitis C virus. Proc Natl Acad Sci USA 1991; 88: 3392-3396.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 3392-3396
    • Ogata, N.1    Alter, H.J.2    Miller, R.H.3    Purcell, R.H.4
  • 2
    • 0026726857 scopus 로고
    • Genetic drift of hepatitis C virus during an 8.2 year infection in a chimpanzee: Variability and stability
    • Okamoto H, Kojima M, Okada S-I et al. Genetic drift of hepatitis C virus during an 8.2 year infection in a chimpanzee: variability and stability. Virol 1992; 190: 894-899.
    • (1992) Virol , vol.190 , pp. 894-899
    • Okamoto, H.1    Kojima, M.2    Okada, S.-I.3
  • 3
    • 0026630482 scopus 로고
    • Genomic characterisation and mutation rate of hepatitis C virus isolated from a patient who contracted hepatitis during an epidemic on non-A, non-B hepatitis in Japan
    • Abe K, Inchauspe G, Fujisawa K. Genomic characterisation and mutation rate of hepatitis C virus isolated from a patient who contracted hepatitis during an epidemic on non-A, non-B hepatitis in Japan. J Gen Virol 1992; 73: 2725-2729.
    • (1992) J Gen Virol , vol.73 , pp. 2725-2729
    • Abe, K.1    Inchauspe, G.2    Fujisawa, K.3
  • 4
    • 0030893694 scopus 로고    scopus 로고
    • Epitope mapping of antibodies directed against hypervariable region 1 in acute self-limiting and chronic infections due to hepatitis C virus
    • Zibert A, Kraas W, Meisel H, Jung G, Roggendorf M. Epitope mapping of antibodies directed against hypervariable region 1 in acute self-limiting and chronic infections due to hepatitis C virus. J Virol 1997; 71: 4123-4127.
    • (1997) J Virol , vol.71 , pp. 4123-4127
    • Zibert, A.1    Kraas, W.2    Meisel, H.3    Jung, G.4    Roggendorf, M.5
  • 5
    • 0031901336 scopus 로고    scopus 로고
    • Long-term evolution of the hypervariable region of hepatitis C virus in a common-source-infected cohort
    • McAllister J, Casino C, Davidson F et al. Long-term evolution of the hypervariable region of hepatitis C virus in a common-source-infected cohort. J Virol 1998; 72: 4893-4905.
    • (1998) J Virol , vol.72 , pp. 4893-4905
    • McAllister, J.1    Casino, C.2    Davidson, F.3
  • 6
    • 0026568641 scopus 로고
    • Evidence for immune selection of hepatitis C virus (HCV) putative envelope glycoprotein variants: Potential role in chronic HCV infections
    • Weiner AJ, Geysen HM, Christopherson C et al. Evidence for immune selection of hepatitis C virus (HCV) putative envelope glycoprotein variants: potential role in chronic HCV infections. Proc Natl Acad Sci USA 1992; 89: 3468-3472.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 3468-3472
    • Weiner, A.J.1    Geysen, H.M.2    Christopherson, C.3
  • 7
    • 0028308318 scopus 로고
    • Genetic drift in hypervariable region 1 of the viral genome in persistent hepatitis C virus infection
    • Kato N, Ootsuyama Y, Sekiya H et al. Genetic drift in hypervariable region 1 of the viral genome in persistent hepatitis C virus infection. J Virol 1994; 68: 4776-4784.
    • (1994) J Virol , vol.68 , pp. 4776-4784
    • Kato, N.1    Ootsuyama, Y.2    Sekiya, H.3
  • 8
    • 0028355846 scopus 로고
    • Genetic alterations of the putative envelope proteins encoding region of the hepatitis C virus in the progression to relapsed phase from acute hepatitis: Humoral immune response to hypervariable region 1
    • Sekiya H, Kato N, Ootsuyama Y et al. Genetic alterations of the putative envelope proteins encoding region of the hepatitis C virus in the progression to relapsed phase from acute hepatitis: humoral immune response to hypervariable region 1. Int J Cancer 1994; 57: 664-670.
    • (1994) Int J Cancer , vol.57 , pp. 664-670
    • Sekiya, H.1    Kato, N.2    Ootsuyama, Y.3
  • 9
    • 0029073169 scopus 로고
    • Occurrence of antibodies reactive with more than one variant of the putative envelope glycoprotein (gp70) hypervariable region 1 in viremic hepatitis C virus-infected patients
    • Scarselli E, Cerino A, Esposito G et al. Occurrence of antibodies reactive with more than one variant of the putative envelope glycoprotein (gp70) hypervariable region 1 in viremic hepatitis C virus-infected patients. J Virol 1995; 69: 4407-1412.
    • (1995) J Virol , vol.69 , pp. 4407-11412
    • Scarselli, E.1    Cerino, A.2    Esposito, G.3
  • 10
    • 0028354145 scopus 로고
    • Hypervariable region of hepatitis C virus envelope glycoprotein (E2 NS1) in an agammaglobulinemic patient
    • Kumar U, Monjardino J, Thomas HC. Hypervariable region of hepatitis C virus envelope glycoprotein (E2 NS1) in an agammaglobulinemic patient. Gastroenterology 1994; 106: 1072-1075.
    • (1994) Gastroenterology , vol.106 , pp. 1072-1075
    • Kumar, U.1    Monjardino, J.2    Thomas, H.C.3
  • 11
    • 0030893672 scopus 로고    scopus 로고
    • Variation of hepatitis C virus hypervariable region 1 in immunocompromised patients
    • Odeberg J, Yun ZB, Sonnerborg A et al. Variation of hepatitis C virus hypervariable region 1 in immunocompromised patients. J Infect Dis 1997; 175: 938-943.
    • (1997) J Infect Dis , vol.175 , pp. 938-943
    • Odeberg, J.1    Yun, Z.B.2    Sonnerborg, A.3
  • 12
    • 0031982502 scopus 로고    scopus 로고
    • Comparison of the rate of sequence variation in the hypervariable region of E2/NS1 region of hepatitis C virus in normal and hypogammaglobulinemic patients
    • Booth JCL, Kumar U, Webster D, Monjardino J, Thomas HC. Comparison of the rate of sequence variation in the hypervariable region of E2/NS1 region of hepatitis C virus in normal and hypogammaglobulinemic patients. Hepatol 1998; 27: 223-227.
    • (1998) Hepatol , vol.27 , pp. 223-227
    • Booth, J.C.L.1    Kumar, U.2    Webster, D.3    Monjardino, J.4    Thomas, H.C.5
  • 13
    • 0029881316 scopus 로고    scopus 로고
    • Hepatitis C in human immunodeficiency virus-coinfected patients: Increased variability in the hypervariable envelope coding domain
    • Sherman KE, Andreatta C, Obrien J, Gutierrez A, Harris R. Hepatitis C in human immunodeficiency virus-coinfected patients: Increased variability in the hypervariable envelope coding domain. Hepatol 1996; 23: 688-694.
    • (1996) Hepatol , vol.23 , pp. 688-694
    • Sherman, K.E.1    Andreatta, C.2    Obrien, J.3    Gutierrez, A.4    Harris, R.5
  • 14
    • 0030993616 scopus 로고    scopus 로고
    • Effect of immunosuppression on composition of quasispecies population of hepatitis C virus in patients with chronic hepatitis C coinfected with human immunodeficiency virus
    • Toyoda H, Fukuda Y, Koyama Y et al. Effect of immunosuppression on composition of quasispecies population of hepatitis C virus in patients with chronic hepatitis C coinfected with human immunodeficiency virus. J Hepatol 1997; 26: 975-982.
    • (1997) J Hepatol , vol.26 , pp. 975-982
    • Toyoda, H.1    Fukuda, Y.2    Koyama, Y.3
  • 15
    • 4244042223 scopus 로고    scopus 로고
    • A quantitative test to estimate neutralizing antibodies to the hepatitis C virus: Cytofluorimetric assessment of envelope glycoprotein 2 binding to target cells
    • Rosa D, Campagnoli S, Moretto C et al. A quantitative test to estimate neutralizing antibodies to the hepatitis C virus: Cytofluorimetric assessment of envelope glycoprotein 2 binding to target cells. Proc Natl Acad Sci USA 1996; 93: 1759-1763.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 1759-1763
    • Rosa, D.1    Campagnoli, S.2    Moretto, C.3
  • 16
    • 0029037291 scopus 로고
    • Antibodies in human sera specific to hypervariable region 1 of hepatitis C virus can block viral attachment
    • Zibert A, Schreier E, Roggendorf M. Antibodies in human sera specific to hypervariable region 1 of hepatitis C virus can block viral attachment. Virol 1995; 208: 653-661.
    • (1995) Virol , vol.208 , pp. 653-661
    • Zibert, A.1    Schreier, E.2    Roggendorf, M.3
  • 17
    • 12644289313 scopus 로고    scopus 로고
    • Prevention of hepatitis C virus infection in chimpanzees by hyperimmune serum against the hypervariable region 1 of the envelope 2 protein
    • Farci P, Shimoda A, Wong D et al. Prevention of hepatitis C virus infection in chimpanzees by hyperimmune serum against the hypervariable region 1 of the envelope 2 protein. Proc Natl Acad Sci USA 1996; 93: 15394-15399.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 15394-15399
    • Farci, P.1    Shimoda, A.2    Wong, D.3
  • 18
    • 0033033612 scopus 로고    scopus 로고
    • Variation of hepatitis C virus following serial transmission: Multiple mechanisms of diversification of the hypervariable region and evidence for convergent evolution
    • Casino C, McAllister J, Davidson F et al. Variation of hepatitis C virus following serial transmission: multiple mechanisms of diversification of the hypervariable region and evidence for convergent evolution. J Gen Virol 1999; 80: 717-725.
    • (1999) J Gen Virol , vol.80 , pp. 717-725
    • Casino, C.1    McAllister, J.2    Davidson, F.3
  • 20
    • 0030846785 scopus 로고    scopus 로고
    • Characteristics of nucleotide substitution in the hepatitis C virus genome: Constraints on sequence change in coding regions at both ends of the genome
    • Smith DB, Simmonds P. Characteristics of nucleotide substitution in the hepatitis C virus genome: constraints on sequence change in coding regions at both ends of the genome. J Mol Evol 1997; 45: 238-246.
    • (1997) J Mol Evol , vol.45 , pp. 238-246
    • Smith, D.B.1    Simmonds, P.2
  • 21
    • 0031017973 scopus 로고    scopus 로고
    • The origin of hepatitis C virus genotypes
    • Smith DB, Pathirana S, Davidson F et al. The origin of hepatitis C virus genotypes. J Gen Virol 1997; 78: 321-328.
    • (1997) J Gen Virol , vol.78 , pp. 321-328
    • Smith, D.B.1    Pathirana, S.2    Davidson, F.3
  • 22
    • 0026335327 scopus 로고
    • Marked sequence diversity in the putative envelope proteins of hepatitis C viruses
    • Kato N, Ootsuyama Y, Tanaka T et al. Marked sequence diversity in the putative envelope proteins of hepatitis C viruses. Virus Res 1992; 22: 107-123.
    • (1992) Virus Res , vol.22 , pp. 107-123
    • Kato, N.1    Ootsuyama, Y.2    Tanaka, T.3
  • 23
    • 0028002086 scopus 로고
    • Sequence variability in the env-coding region of hepatitis C virus isolated from patients infected during a single source outbreak
    • Hohne M, Schreier E, Roggendorf M. Sequence variability in the env-coding region of hepatitis C virus isolated from patients infected during a single source outbreak. Arch Virol 1994; 137: 25-34.
    • (1994) Arch Virol , vol.137 , pp. 25-34
    • Hohne, M.1    Schreier, E.2    Roggendorf, M.3
  • 24
    • 0029027677 scopus 로고
    • Dynamic analysis of heterogeneous hepatitis C virus populations by direct solid-phase sequencing
    • Odeberg J, Yun ZB, Sonnerborg A, Uhlen M, Lundeberg J. Dynamic analysis of heterogeneous hepatitis C virus populations by direct solid-phase sequencing. J Clin Microbiol 1995; 33: 1870-1874.
    • (1995) J Clin Microbiol , vol.33 , pp. 1870-1874
    • Odeberg, J.1    Yun, Z.B.2    Sonnerborg, A.3    Uhlen, M.4    Lundeberg, J.5
  • 25
    • 0027397555 scopus 로고
    • Sequence variation in the large envelope glycoprotein (E2/NS1) of hepatitis C virus during chronic infection
    • Kumar U, Brown J, Monjardino J, Thomas HC. Sequence variation in the large envelope glycoprotein (E2/NS1) of hepatitis C virus during chronic infection. J Infect Dis 1993; 167: 726-730.
    • (1993) J Infect Dis , vol.167 , pp. 726-730
    • Kumar, U.1    Brown, J.2    Monjardino, J.3    Thomas, H.C.4
  • 26
    • 0027369206 scopus 로고
    • Dynamics of genome change in the E2/NS1 region of hepatitis C virus in vivo
    • Higashi Y, Kakumu S, Yoshioka K et al. Dynamics of genome change in the E2/NS1 region of hepatitis C virus in vivo. Virol 1993; 197: 659-668.
    • (1993) Virol , vol.197 , pp. 659-668
    • Higashi, Y.1    Kakumu, S.2    Yoshioka, K.3
  • 27
    • 0029024922 scopus 로고
    • Quasispecies of Hepatitis C virus and Genetic Drift of the Hypervariable region in Chronic Type C hepatitis
    • Kao JH, Chen PJ, Lai MY, Wang TH, Chen DS. Quasispecies of Hepatitis C virus and Genetic Drift of the Hypervariable region in Chronic Type C hepatitis. J Infect Dis 1995; 172: 261-264.
    • (1995) J Infect Dis , vol.172 , pp. 261-264
    • Kao, J.H.1    Chen, P.J.2    Lai, M.Y.3    Wang, T.H.4    Chen, D.S.5
  • 28
    • 0028001698 scopus 로고
    • Influence of antibodies to the hypervariable region of E2/NS1 glycoprotein on the selective replication of hepatitis C virus in chimpanzees
    • Kojima M, Osuga T, Tsuda F, Tanaka T, Okamoto H. Influence of antibodies to the hypervariable region of E2/NS1 glycoprotein on the selective replication of hepatitis C virus in chimpanzees. Virol 1994; 204: 665-672.
    • (1994) Virol , vol.204 , pp. 665-672
    • Kojima, M.1    Osuga, T.2    Tsuda, F.3    Tanaka, T.4    Okamoto, H.5
  • 29
    • 0028870181 scopus 로고
    • Sequence evolution of the hypervariable region in the putative envelope region E2/NS1 of hepatitis C virus is correlated with specific humoral immune responses
    • Vandoorn LJ, Capriles I, Maertens G et al. Sequence evolution of the hypervariable region in the putative envelope region E2/NS1 of hepatitis C virus is correlated with specific humoral immune responses. J Virol 1995; 69: 773-778.
    • (1995) J Virol , vol.69 , pp. 773-778
    • Vandoorn, L.J.1    Capriles, I.2    Maertens, G.3
  • 30
    • 0031936597 scopus 로고    scopus 로고
    • Immunity in chimpanzees chronically infected with hepatitis C virus: Role of minor quasispecies in reinfection
    • Wyatt CA, Andrus L, Brotman B et al. Immunity in chimpanzees chronically infected with hepatitis C virus: Role of minor quasispecies in reinfection. J Virol 1998; 72: 1725-1730.
    • (1998) J Virol , vol.72 , pp. 1725-1730
    • Wyatt, C.A.1    Andrus, L.2    Brotman, B.3
  • 31
    • 0026703267 scopus 로고
    • The degree of variability in the amino terminal region of the E2/NS1 protein of hepatitis C virus corrleates with responsiveness to interferon therapy in viraemic patients
    • Okada S-I, Akahane Y, Suzuki H, Okamoto H, Mishiro S. The degree of variability in the amino terminal region of the E2/NS1 protein of hepatitis C virus corrleates with responsiveness to interferon therapy in viraemic patients. Hepatol 1992; 16: 619-624.
    • (1992) Hepatol , vol.16 , pp. 619-624
    • Okada, S.-I.1    Akahane, Y.2    Suzuki, H.3    Okamoto, H.4    Mishiro, S.5
  • 32
    • 0031958419 scopus 로고    scopus 로고
    • Evolution of hepatitis C virus quasispecies in hypervariable region 1 and the putative interferon sensitivity-determining region during interferon therapy and natural infection
    • Polyak SJ, McArdle S, Liu SL et al. Evolution of hepatitis C virus quasispecies in hypervariable region 1 and the putative interferon sensitivity-determining region during interferon therapy and natural infection. J Virol 1998; 72: 4288-4296.
    • (1998) J Virol , vol.72 , pp. 4288-4296
    • Polyak, S.J.1    McArdle, S.2    Liu, S.L.3
  • 33
    • 0031749172 scopus 로고    scopus 로고
    • Evolution of hypervariable region 1 of hepatitis C virus in primary infection
    • Manzin A, Solforosi L, Petrelli E et al. Evolution of hypervariable region 1 of hepatitis C virus in primary infection. J Virol 1998; 72: 6271-6276.
    • (1998) J Virol , vol.72 , pp. 6271-6276
    • Manzin, A.1    Solforosi, L.2    Petrelli, E.3
  • 34
    • 0027934221 scopus 로고
    • Frequent reinfection and reactivation of hepatitis C virus genotypes in multitransfused hemophiliacs
    • Jarvis LM, Watson HG, McOmish F et al. Frequent reinfection and reactivation of hepatitis C virus genotypes in multitransfused hemophiliacs. J Infect Dis 1994; 170: 1018-1022.
    • (1994) J Infect Dis , vol.170 , pp. 1018-1022
    • Jarvis, L.M.1    Watson, H.G.2    McOmish, F.3
  • 35
    • 8944249298 scopus 로고    scopus 로고
    • Maintaining the integrity of human immunodeficiency virus sequence databases
    • Learn GH, Korber BTM, Foley B et al. Maintaining the integrity of human immunodeficiency virus sequence databases. J Virol 1996; 70: 5720-5730.
    • (1996) J Virol , vol.70 , pp. 5720-5730
    • Learn, G.H.1    Korber, B.T.M.2    Foley, B.3
  • 36
    • 0029860266 scopus 로고    scopus 로고
    • Hypervariable region sequence in cryoglobulin-associated hepatitis C virus in sera of patients with chronic hepatitis C. Relationship to antibody response against hypervariable region genome
    • Aiyama T, Yoshioka K, Okumura A et al. Hypervariable region sequence in cryoglobulin-associated hepatitis C virus in sera of patients with chronic hepatitis C. Relationship to antibody response against hypervariable region genome. Hepatol 1996; 24: 1346-1350.
    • (1996) Hepatol , vol.24 , pp. 1346-1350
    • Aiyama, T.1    Yoshioka, K.2    Okumura, A.3
  • 37
    • 0030878535 scopus 로고    scopus 로고
    • Virus 'quasispecies': Making a mountain out of a molehill?
    • Smith DB, McAllister J, Casino C, Simmonds P. Virus 'quasispecies': Making a mountain out of a molehill? J Gen Virol 1997; 78: 1511-1519.
    • (1997) J Gen Virol , vol.78 , pp. 1511-1519
    • Smith, D.B.1    McAllister, J.2    Casino, C.3    Simmonds, P.4
  • 38
    • 0027304173 scopus 로고
    • A structurally flexible and antigenically variable n-terminal domain of the hepatitis C virus E2/NS1 protein - Implication for an escape from antibody
    • Taniguchi S, Okamoto H, Sakamoto M et al. A structurally flexible and antigenically variable n-terminal domain of the hepatitis C virus E2/NS1 protein - implication for an escape from antibody. Viol 1993; 195: 29 7-301.
    • (1993) Viol , vol.195 , pp. 297-301
    • Taniguchi, S.1    Okamoto, H.2    Sakamoto, M.3
  • 39
    • 0028230023 scopus 로고
    • Genetic alteration of the hepatitis C virus hypervariable region obtained from an asymptomatic carrier
    • Nakazawa T, Kato N, Ootsuyama Y et al. Genetic alteration of the hepatitis C virus hypervariable region obtained from an asymptomatic carrier. Int J Cancer 1994; 56: 204-207.
    • (1994) Int J Cancer , vol.56 , pp. 204-207
    • Nakazawa, T.1    Kato, N.2    Ootsuyama, Y.3
  • 40
    • 0027974113 scopus 로고
    • Evolution and selection of hepatitis C virus variants in patients with chronic hepatitis C
    • Kurosaki M, Enomoto N, Marumo F, Sato C. Evolution and selection of hepatitis C virus variants in patients with chronic hepatitis C. Virol 1994; 205: 161-169.
    • (1994) Virol , vol.205 , pp. 161-169
    • Kurosaki, M.1    Enomoto, N.2    Marumo, F.3    Sato, C.4
  • 41
    • 0030065866 scopus 로고    scopus 로고
    • Specific detection of hepatitis C virus minus strand RNA in hematopoietic cells
    • Lerat H, Berby F, Trabaud MA et al. Specific detection of hepatitis C virus minus strand RNA in hematopoietic cells. J Clin Invest 1996; 97: 845-851.
    • (1996) J Clin Invest , vol.97 , pp. 845-851
    • Lerat, H.1    Berby, F.2    Trabaud, M.A.3
  • 42
    • 0031902868 scopus 로고    scopus 로고
    • Low level or absent in vivo replication of hepatitis C virus and hepatitis G virus/GB virus C in peripheral blood mononuclear cells
    • Mellor J, Haydon GH, Blair C, Livingstone WJ, Simmonds P. Low level or absent in vivo replication of hepatitis C virus and hepatitis G virus/GB virus C in peripheral blood mononuclear cells. J Gen Virol 1998; 79: 705-714.
    • (1998) J Gen Virol , vol.79 , pp. 705-714
    • Mellor, J.1    Haydon, G.H.2    Blair, C.3    Livingstone, W.J.4    Simmonds, P.5
  • 43
    • 0030837422 scopus 로고    scopus 로고
    • Sequence analysis of the hepatitis C virus genome recovered from serum, liver, and peripheral blood mononuclear cells of infected chimpanzees
    • Shimizu YK, Igarashi H, Kanematu T et al. Sequence analysis of the hepatitis C virus genome recovered from serum, liver, and peripheral blood mononuclear cells of infected chimpanzees. J Virol 1997; 71: 5769-5773.
    • (1997) J Virol , vol.71 , pp. 5769-5773
    • Shimizu, Y.K.1    Igarashi, H.2    Kanematu, T.3
  • 44
    • 0029787201 scopus 로고    scopus 로고
    • Comparison of hypervariable regions (HVR1 and HVR2) in positive-and negative-stranded hepatitis C virus RNA in cancerous and non-cancerous liver tissue, peripheral blood mononuclear cells and serum from a patient with hepatoccllular carcinoma
    • Saito S, Kato N, Hijikata M et al. Comparison of hypervariable regions (HVR1 and HVR2) in positive-and negative-stranded hepatitis C virus RNA in cancerous and non-cancerous liver tissue, peripheral blood mononuclear cells and serum from a patient with hepatoccllular carcinoma. Int J Cancer 1996; 67: 199-203.
    • (1996) Int J Cancer , vol.67 , pp. 199-203
    • Saito, S.1    Kato, N.2    Hijikata, M.3
  • 45
    • 0030878538 scopus 로고    scopus 로고
    • Differences in hepatitis C virus quasispecies composition between liver, peripheral blood mononuclear cells and plasma
    • Maggi F, Fornai C, Vatteroni ML et al. Differences in hepatitis C virus quasispecies composition between liver, peripheral blood mononuclear cells and plasma. J Gen Virol 1997; 78: 1521-1525.
    • (1997) J Gen Virol , vol.78 , pp. 1521-1525
    • Maggi, F.1    Fornai, C.2    Vatteroni, M.L.3
  • 46
    • 0031932434 scopus 로고    scopus 로고
    • Genetic diversity and tissue compartmentalization of the hepatitis C virus genome in blood mononuclear cells, liver, and serum from chronic hepatitis C patients
    • Navas S, Martin J, Quiroga JA, Castillo I, Carreno V. Genetic diversity and tissue compartmentalization of the hepatitis C virus genome in blood mononuclear cells, liver, and serum from chronic hepatitis C patients. J Virol 1998; 72: 1640-1646.
    • (1998) J Virol , vol.72 , pp. 1640-1646
    • Navas, S.1    Martin, J.2    Quiroga, J.A.3    Castillo, I.4    Carreno, V.5
  • 47
    • 0027223705 scopus 로고
    • Humoral immune response to hypervariable region-1 of the putative envelope glycoprotein (gp70) of hepatitis C virus
    • Kato N, Sekiya H, Ootsuyama Y et al. Humoral immune response to hypervariable region-1 of the putative envelope glycoprotein (gp70) of hepatitis C virus. J Virol 1993; 67: 3923-3930.
    • (1993) J Virol , vol.67 , pp. 3923-3930
    • Kato, N.1    Sekiya, H.2    Ootsuyama, Y.3
  • 48
    • 0030175958 scopus 로고    scopus 로고
    • Deficiency of antibody response to hypervariable region of hepatitis C virus in patients with chronic hepatitis C
    • Yoshioka K, Higashi Y, Tanaka K et al. Deficiency of antibody response to hypervariable region of hepatitis C virus in patients with chronic hepatitis C. J Hepatol 1996; 24: 649-657.
    • (1996) J Hepatol , vol.24 , pp. 649-657
    • Yoshioka, K.1    Higashi, Y.2    Tanaka, K.3
  • 49
    • 0030838676 scopus 로고    scopus 로고
    • Identification of GB virus C variants by phylogenetic analysis of 5′-untranslated and coding region sequences
    • Muerhoff AS, Smith DB, Leary TP et al. Identification of GB virus C variants by phylogenetic analysis of 5′-untranslated and coding region sequences. J Virol 1997; 71: 6501-6508.
    • (1997) J Virol , vol.71 , pp. 6501-6508
    • Muerhoff, A.S.1    Smith, D.B.2    Leary, T.P.3
  • 50
    • 0030849334 scopus 로고    scopus 로고
    • Mutation rate of GB virus C hepatitis G virus over the entire genome and in subgenomic regions
    • Nakao H, Okamoto H, Fukuda M et al. Mutation rate of GB virus C hepatitis G virus over the entire genome and in subgenomic regions. Virol 1997; 233: 43-50.
    • (1997) Virol , vol.233 , pp. 43-50
    • Nakao, H.1    Okamoto, H.2    Fukuda, M.3
  • 51
    • 0027979266 scopus 로고
    • ODEN: A program package for molecular evolutionary analysis and database search of DNA and amino acid sequences
    • Ina Y. ODEN: a program package for molecular evolutionary analysis and database search of DNA and amino acid sequences. Comput Appl Biosci 1994; 10: 11-12.
    • (1994) Comput Appl Biosci , vol.10 , pp. 11-12
    • Ina, Y.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.