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Volumn 67, Issue 1, 2008, Pages 64-70

Efficacy and safety of pemetrexed in elderly cancer patients: Results of an integrated analysis

Author keywords

Chemotherapy; Elderly; Integrated study; Mesothelioma; Metastatic cancer; Non small cell lung cancer; Pancreatic cancer; Pemetrexed; Pooled study

Indexed keywords

CISPLATIN; CYANOCOBALAMIN; DEXAMETHASONE; DOCETAXEL; FOLIC ACID; GEMCITABINE; PEMETREXED;

EID: 44649133200     PISSN: 10408428     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.critrevonc.2008.01.011     Document Type: Review
Times cited : (13)

References (38)
  • 2
    • 0037093947 scopus 로고    scopus 로고
    • Annual report to the nation on the status of cancer, 1973-1999, featuring implications of age and aging on U.S. cancer burden
    • Edwards B.K., Howe H.L., Ries L.A., Thun M.J., Rosenberg H.M., Yancik R., et al. Annual report to the nation on the status of cancer, 1973-1999, featuring implications of age and aging on U.S. cancer burden. Cancer 94 10 (2002) 2766-2792
    • (2002) Cancer , vol.94 , Issue.10 , pp. 2766-2792
    • Edwards, B.K.1    Howe, H.L.2    Ries, L.A.3    Thun, M.J.4    Rosenberg, H.M.5    Yancik, R.6
  • 3
    • 44649164199 scopus 로고    scopus 로고
    • SEER cancer statistics review, 1975-2004. Bethesda, MD: National Cancer Institute; 2007 (accessed at http://seer.cancer.gov/csr/1975_2004).
    • SEER cancer statistics review, 1975-2004. Bethesda, MD: National Cancer Institute; 2007 (accessed at http://seer.cancer.gov/csr/1975_2004).
  • 4
    • 44649116825 scopus 로고    scopus 로고
    • Cancer in the elderly: focus on pharmacotherapy
    • Ignoffo R. Cancer in the elderly: focus on pharmacotherapy. US Pharm 26 (2001) HS26-HS35
    • (2001) US Pharm , vol.26
    • Ignoffo, R.1
  • 5
    • 0030886129 scopus 로고    scopus 로고
    • Cancer burden in the aged: an epidemiologic and demographic overview
    • Yancik R. Cancer burden in the aged: an epidemiologic and demographic overview. Cancer 80 7 (1997) 1273-1283
    • (1997) Cancer , vol.80 , Issue.7 , pp. 1273-1283
    • Yancik, R.1
  • 8
    • 4544328968 scopus 로고    scopus 로고
    • Greater risks of chemotherapy toxicity in elderly patients with cancer
    • Repetto L. Greater risks of chemotherapy toxicity in elderly patients with cancer. J Support Oncol 1 4 Suppl 2 (2003) 18-24
    • (2003) J Support Oncol , vol.1 , Issue.4 SUPPL. 2 , pp. 18-24
    • Repetto, L.1
  • 9
    • 4444351115 scopus 로고    scopus 로고
    • Pemetrexed: a novel antifolate agent enters clinical practice
    • Kut V., Patel J.D., and Argiris A. Pemetrexed: a novel antifolate agent enters clinical practice. Expert Rev Anticancer Ther 4 4 (2004) 511-522
    • (2004) Expert Rev Anticancer Ther , vol.4 , Issue.4 , pp. 511-522
    • Kut, V.1    Patel, J.D.2    Argiris, A.3
  • 10
    • 13744252016 scopus 로고    scopus 로고
    • Biochemical pharmacology of pemetrexed
    • Calvert A.H. Biochemical pharmacology of pemetrexed. Oncology (Williston Park) 18 13 Suppl 8 (2004) 13-17
    • (2004) Oncology (Williston Park) , vol.18 , Issue.13 SUPPL. 8 , pp. 13-17
    • Calvert, A.H.1
  • 12
    • 15444374157 scopus 로고    scopus 로고
    • Pemetrexed therapy for malignant pleural mesothelioma
    • Puto K., and Garey J.S. Pemetrexed therapy for malignant pleural mesothelioma. Ann Pharmacother 39 4 (2005) 678-683
    • (2005) Ann Pharmacother , vol.39 , Issue.4 , pp. 678-683
    • Puto, K.1    Garey, J.S.2
  • 13
    • 13744259507 scopus 로고    scopus 로고
    • Pemetrexed in second-line treatment of non-small-cell lung cancer
    • De Marinis F., and De Petris L. Pemetrexed in second-line treatment of non-small-cell lung cancer. Oncology (Williston Park) 18 13 Suppl 8 (2004) 38-42
    • (2004) Oncology (Williston Park) , vol.18 , Issue.13 SUPPL. 8 , pp. 38-42
    • De Marinis, F.1    De Petris, L.2
  • 14
    • 2442661845 scopus 로고    scopus 로고
    • Randomized phase III trial of pemetrexed versus docetaxel in patients with non-small-cell lung cancer previously treated with chemotherapy
    • Hanna N., Shepherd F.A., Fossella F.V., Pereira J.R., De Marinis F., von Pawel J., et al. Randomized phase III trial of pemetrexed versus docetaxel in patients with non-small-cell lung cancer previously treated with chemotherapy. J Clin Oncol 22 9 (2004) 1589-1597
    • (2004) J Clin Oncol , vol.22 , Issue.9 , pp. 1589-1597
    • Hanna, N.1    Shepherd, F.A.2    Fossella, F.V.3    Pereira, J.R.4    De Marinis, F.5    von Pawel, J.6
  • 15
    • 27144530079 scopus 로고    scopus 로고
    • A phase III trial of pemetrexed plus gemcitabine versus gemcitabine in patients with unresectable or metastatic pancreatic cancer
    • Oettle H., Richards D., Ramanathan R.K., van Laethem J.L., Peeters M., Fuchs M., et al. A phase III trial of pemetrexed plus gemcitabine versus gemcitabine in patients with unresectable or metastatic pancreatic cancer. Ann Oncol 16 10 (2005) 1639-1645
    • (2005) Ann Oncol , vol.16 , Issue.10 , pp. 1639-1645
    • Oettle, H.1    Richards, D.2    Ramanathan, R.K.3    van Laethem, J.L.4    Peeters, M.5    Fuchs, M.6
  • 16
    • 0041629528 scopus 로고    scopus 로고
    • Phase III study of pemetrexed in combination with cisplatin versus cisplatin alone in patients with malignant pleural mesothelioma
    • Vogelzang N.J., Rusthoven J.J., Symanowski J., Denham C., Kaukel E., Ruffie P., et al. Phase III study of pemetrexed in combination with cisplatin versus cisplatin alone in patients with malignant pleural mesothelioma. J Clin Oncol 21 14 (2003) 2636-2644
    • (2003) J Clin Oncol , vol.21 , Issue.14 , pp. 2636-2644
    • Vogelzang, N.J.1    Rusthoven, J.J.2    Symanowski, J.3    Denham, C.4    Kaukel, E.5    Ruffie, P.6
  • 17
    • 0016799829 scopus 로고
    • Sequential treatment assignment with balancing for prognostic factors in the controlled clinical trial
    • Pocock S.J., and Simon R. Sequential treatment assignment with balancing for prognostic factors in the controlled clinical trial. Biometrics 31 1 (1975) 103-115
    • (1975) Biometrics , vol.31 , Issue.1 , pp. 103-115
    • Pocock, S.J.1    Simon, R.2
  • 18
    • 8244258015 scopus 로고    scopus 로고
    • Cancer patient survival in the elderly in Italy
    • ITACARE Working Group
    • Vercelli M., Quaglia A., Casella C., Mangone L., and ITACARE Working Group. Cancer patient survival in the elderly in Italy. Tumori 83 1 (1997) 490-496
    • (1997) Tumori , vol.83 , Issue.1 , pp. 490-496
    • Vercelli, M.1    Quaglia, A.2    Casella, C.3    Mangone, L.4
  • 19
    • 26444514977 scopus 로고    scopus 로고
    • Clinical pharmacology issues relevant to the dosing and toxicity of chemotherapy drugs in the elderly
    • Wasil T., and Lichtman S.M. Clinical pharmacology issues relevant to the dosing and toxicity of chemotherapy drugs in the elderly. Oncologist 10 8 (2005) 602-612
    • (2005) Oncologist , vol.10 , Issue.8 , pp. 602-612
    • Wasil, T.1    Lichtman, S.M.2
  • 20
    • 0036140654 scopus 로고    scopus 로고
    • Therapy choices among older patients with lung carcinoma: an evaluation of two trials of the Cancer and Leukemia Group B
    • Rocha Lima C.M., Herndon J.E., Kosty M., Clamon G., and Green M.R. Therapy choices among older patients with lung carcinoma: an evaluation of two trials of the Cancer and Leukemia Group B. Cancer 94 1 (2002) 181-187
    • (2002) Cancer , vol.94 , Issue.1 , pp. 181-187
    • Rocha Lima, C.M.1    Herndon, J.E.2    Kosty, M.3    Clamon, G.4    Green, M.R.5
  • 21
    • 0141465153 scopus 로고    scopus 로고
    • The outcome of combined-modality therapy for stage III non-small-cell lung cancer in the elderly
    • Schild S.E., Stella P.J., Geyer S.M., Bonner J.A., McGinnis W.L., Mailliard J.A., et al. The outcome of combined-modality therapy for stage III non-small-cell lung cancer in the elderly. J Clin Oncol 21 17 (2003) 3201-3206
    • (2003) J Clin Oncol , vol.21 , Issue.17 , pp. 3201-3206
    • Schild, S.E.1    Stella, P.J.2    Geyer, S.M.3    Bonner, J.A.4    McGinnis, W.L.5    Mailliard, J.A.6
  • 22
    • 0141688376 scopus 로고    scopus 로고
    • Aggressive treatment for the fit elderly with non-small-cell lung cancer? Yes!
    • Sequist L.V., and Lynch T.J. Aggressive treatment for the fit elderly with non-small-cell lung cancer? Yes!. J Clin Oncol 21 17 (2003) 3186-3188
    • (2003) J Clin Oncol , vol.21 , Issue.17 , pp. 3186-3188
    • Sequist, L.V.1    Lynch, T.J.2
  • 23
    • 0344980098 scopus 로고    scopus 로고
    • Gemcitabine plus vinorelbine in nonsmall cell lung carcinoma patients age 70 years or older or patients who cannot receive cisplatin
    • Oncopaz Cooperative Group
    • Feliu J., et al., Oncopaz Cooperative Group. Gemcitabine plus vinorelbine in nonsmall cell lung carcinoma patients age 70 years or older or patients who cannot receive cisplatin. Cancer 86 8 (1999) 1463-1469
    • (1999) Cancer , vol.86 , Issue.8 , pp. 1463-1469
    • Feliu, J.1
  • 24
    • 9844245135 scopus 로고    scopus 로고
    • Cisplatin-based combination chemotherapy for elderly patients with non-small-cell lung cancer
    • Kubota K., Furuse K., Kawahara M., Kodama N., Ogawara M., Takada M., et al. Cisplatin-based combination chemotherapy for elderly patients with non-small-cell lung cancer. Cancer Chemother Pharmacol 40 6 (1997) 469-474
    • (1997) Cancer Chemother Pharmacol , vol.40 , Issue.6 , pp. 469-474
    • Kubota, K.1    Furuse, K.2    Kawahara, M.3    Kodama, N.4    Ogawara, M.5    Takada, M.6
  • 25
    • 0001323349 scopus 로고
    • Correlation between age and prognosis in patients with advanced non-small-cell lung cancer prognosis with cisplatin containing chemotherapy: a retrospective multicenter study
    • Rinaldi M., de Marinis F., and Ardizzoni A. Correlation between age and prognosis in patients with advanced non-small-cell lung cancer prognosis with cisplatin containing chemotherapy: a retrospective multicenter study. Ann Oncol 5 Suppl 8 (1994) 58
    • (1994) Ann Oncol , vol.5 , Issue.SUPPL. 8 , pp. 58
    • Rinaldi, M.1    de Marinis, F.2    Ardizzoni, A.3
  • 26
    • 0037028750 scopus 로고    scopus 로고
    • Cisplatin-based therapy for elderly patients with advanced non-small-cell lung cancer: implications of Eastern Cooperative Oncology Group 5592, a randomized trial
    • Langer C.J., Manola J., Bernardo P., Kugler J.W., Bonomi P., Cella D., et al. Cisplatin-based therapy for elderly patients with advanced non-small-cell lung cancer: implications of Eastern Cooperative Oncology Group 5592, a randomized trial. J Natl Cancer Inst 94 3 (2002) 173-181
    • (2002) J Natl Cancer Inst , vol.94 , Issue.3 , pp. 173-181
    • Langer, C.J.1    Manola, J.2    Bernardo, P.3    Kugler, J.W.4    Bonomi, P.5    Cella, D.6
  • 27
    • 16644396077 scopus 로고    scopus 로고
    • Single-agent versus combination chemotherapy in advanced non-small-cell lung cancer: the cancer and leukemia group B (study 9730)
    • Lilenbaum R.C., Herndon J.E., List M.A., Desch C., Watson D.M., Miller A.A., et al. Single-agent versus combination chemotherapy in advanced non-small-cell lung cancer: the cancer and leukemia group B (study 9730). J Clin Oncol 23 1 (2005) 190-196
    • (2005) J Clin Oncol , vol.23 , Issue.1 , pp. 190-196
    • Lilenbaum, R.C.1    Herndon, J.E.2    List, M.A.3    Desch, C.4    Watson, D.M.5    Miller, A.A.6
  • 29
    • 0037014798 scopus 로고    scopus 로고
    • Re: Cisplatin-based therapy for elderly patients with advanced non-small-cell lung cancer: implications of Eastern Cooperative Oncology Group 5592, a randomized trial
    • 1029-1030, author reply 30-31
    • Perrone F., Gallo C., and Gridelli C. Re: Cisplatin-based therapy for elderly patients with advanced non-small-cell lung cancer: implications of Eastern Cooperative Oncology Group 5592, a randomized trial. J Natl Cancer Inst 94 13 (2002) 1029-1030, author reply 30-31
    • (2002) J Natl Cancer Inst , vol.94 , Issue.13
    • Perrone, F.1    Gallo, C.2    Gridelli, C.3
  • 30
    • 0034861227 scopus 로고    scopus 로고
    • Pemetrexed disodium: a novel antifolate clinically active against multiple solid tumors
    • Hanauske A.R., Chen V., Paoletti P., and Niyikiza C. Pemetrexed disodium: a novel antifolate clinically active against multiple solid tumors. Oncologist 6 4 (2001) 363-373
    • (2001) Oncologist , vol.6 , Issue.4 , pp. 363-373
    • Hanauske, A.R.1    Chen, V.2    Paoletti, P.3    Niyikiza, C.4
  • 31
    • 0036562507 scopus 로고    scopus 로고
    • Homocysteine and methylmalonic acid: markers to predict and avoid toxicity from pemetrexed therapy
    • Niyikiza C., Baker S.D., Seitz D.E., Walling J.M., Nelson K., Rusthoven J.J., et al. Homocysteine and methylmalonic acid: markers to predict and avoid toxicity from pemetrexed therapy. Mol Cancer Ther 1 7 (2002) 545-552
    • (2002) Mol Cancer Ther , vol.1 , Issue.7 , pp. 545-552
    • Niyikiza, C.1    Baker, S.D.2    Seitz, D.E.3    Walling, J.M.4    Nelson, K.5    Rusthoven, J.J.6
  • 32
    • 0019378585 scopus 로고
    • Dose-response effect of adjuvant chemotherapy in breast cancer
    • Bonadonna G., and Valagussa P. Dose-response effect of adjuvant chemotherapy in breast cancer. N Engl J Med 304 1 (1981) 10-15
    • (1981) N Engl J Med , vol.304 , Issue.1 , pp. 10-15
    • Bonadonna, G.1    Valagussa, P.2
  • 33
    • 0142085807 scopus 로고    scopus 로고
    • Factors associated with early termination of CHOP therapy and the impact on survival among patients with chemosensitive intermediate-grade non-Hodgkin's lymphoma
    • Chrischilles E.A., Link B.K., Scott S.D., Delgado D.J., and Fridman M. Factors associated with early termination of CHOP therapy and the impact on survival among patients with chemosensitive intermediate-grade non-Hodgkin's lymphoma. Cancer Control 10 5 (2003) 396-403
    • (2003) Cancer Control , vol.10 , Issue.5 , pp. 396-403
    • Chrischilles, E.A.1    Link, B.K.2    Scott, S.D.3    Delgado, D.J.4    Fridman, M.5
  • 34
    • 1542753592 scopus 로고    scopus 로고
    • Incidence and predictors of low dose-intensity in adjuvant breast cancer chemotherapy: a nationwide study of community practices
    • Lyman G.H., Dale D.C., and Crawford J. Incidence and predictors of low dose-intensity in adjuvant breast cancer chemotherapy: a nationwide study of community practices. J Clin Oncol 21 24 (2003) 4524-4531
    • (2003) J Clin Oncol , vol.21 , Issue.24 , pp. 4524-4531
    • Lyman, G.H.1    Dale, D.C.2    Crawford, J.3
  • 35
    • 0022602852 scopus 로고
    • Effect of age on therapeutic outcome in advanced diffuse histiocytic lymphoma: the Southwest Oncology Group experience
    • Dixon D.O., Neilan B., Jones S.E., Lipschitz D.A., Miller T.P., Grozea P.N., et al. Effect of age on therapeutic outcome in advanced diffuse histiocytic lymphoma: the Southwest Oncology Group experience. J Clin Oncol 4 3 (1986) 295-305
    • (1986) J Clin Oncol , vol.4 , Issue.3 , pp. 295-305
    • Dixon, D.O.1    Neilan, B.2    Jones, S.E.3    Lipschitz, D.A.4    Miller, T.P.5    Grozea, P.N.6
  • 36
    • 0037050352 scopus 로고    scopus 로고
    • Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer
    • Schiller J.H., Harrington D., Belani C.P., Langer C., Sandler A., Krook J., et al. Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer. N Engl J Med 346 2 (2002) 92-98
    • (2002) N Engl J Med , vol.346 , Issue.2 , pp. 92-98
    • Schiller, J.H.1    Harrington, D.2    Belani, C.P.3    Langer, C.4    Sandler, A.5    Krook, J.6
  • 37
    • 0041570235 scopus 로고    scopus 로고
    • The impact of age on toxicity, response rate, quality of life, and survival in patients with advanced: stage IIIB or IV nonsmall cell lung carcinoma treated with carboplatin and paclitaxel
    • Hensing T.A., Peterman A.H., Schell M.J., Lee J.H., and Socinski M.A. The impact of age on toxicity, response rate, quality of life, and survival in patients with advanced: stage IIIB or IV nonsmall cell lung carcinoma treated with carboplatin and paclitaxel. Cancer 98 4 (2003) 779-788
    • (2003) Cancer , vol.98 , Issue.4 , pp. 779-788
    • Hensing, T.A.1    Peterman, A.H.2    Schell, M.J.3    Lee, J.H.4    Socinski, M.A.5
  • 38
    • 0029761682 scopus 로고    scopus 로고
    • Determinants of survival in older cancer patients
    • Goodwin J.S., Samet J.M., and Hunt W.C. Determinants of survival in older cancer patients. J Natl Cancer Inst 88 15 (1996) 1031-1038
    • (1996) J Natl Cancer Inst , vol.88 , Issue.15 , pp. 1031-1038
    • Goodwin, J.S.1    Samet, J.M.2    Hunt, W.C.3


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