메뉴 건너뛰기




Volumn 60, Issue 5, 2008, Pages 483-492

Contribution of the primary sensory neurons and spinal glial cells to the pathomechanisms of neuropathic pain

Author keywords

Glia; MAPK; Neuropathic pain; Neurotrophic factor; TRP

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CALCITONIN GENE RELATED PEPTIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; NEUROTROPIC AGENT; SUBSTANCE P; VANILLOID RECEPTOR 1;

EID: 44449162257     PISSN: 00068969     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (15)

References (31)
  • 1
    • 0037704450 scopus 로고    scopus 로고
    • Differential activation of extracellular signal-regulated protein kinase in primary afferent neurons regulates brain-derived neurotrophic factor expression after peripheral inflammation and nerve injury
    • Obata K, Yamanaka H, Dai Y, Tachibana T, Fukuoka T, et al: Differential activation of extracellular signal-regulated protein kinase in primary afferent neurons regulates brain-derived neurotrophic factor expression after peripheral inflammation and nerve injury. J Neurosci 23: 4117-4126, 2003
    • (2003) J Neurosci , vol.23 , pp. 4117-4126
    • Obata, K.1    Yamanaka, H.2    Dai, Y.3    Tachibana, T.4    Fukuoka, T.5
  • 2
    • 8544239374 scopus 로고    scopus 로고
    • Role of mitogen-activated protein kinase activation in injured and intact primary afferent neurons for mechanical and heat hypersensitivity after spinal nerve ligation
    • Obata K, Yamanaka H, Kobayashi K, Dai Y, Mizushima T, et al: Role of mitogen-activated protein kinase activation in injured and intact primary afferent neurons for mechanical and heat hypersensitivity after spinal nerve ligation. J Neurosci 24: 10211-10222, 2004
    • (2004) J Neurosci , vol.24 , pp. 10211-10222
    • Obata, K.1    Yamanaka, H.2    Kobayashi, K.3    Dai, Y.4    Mizushima, T.5
  • 3
    • 0036700128 scopus 로고    scopus 로고
    • Contribution of the spared primary afferent neurons to the pathomechanisms of neuropathic pain
    • Fukuoka T, Noguchi K: Contribution of the spared primary afferent neurons to the pathomechanisms of neuropathic pain. Mol Neurobiol 26: 57-67, 2002
    • (2002) Mol Neurobiol , vol.26 , pp. 57-67
    • Fukuoka, T.1    Noguchi, K.2
  • 4
    • 0037223202 scopus 로고    scopus 로고
    • Contribution of injured and uninjured dorsal root ganglion neurons to pain behavior and the changes in gene expression following chronic constriction injury of the sciatic nerve in rats
    • Obata K, Yamanaka H, Fukuoka T, Dai Y, Tokunaga A, et al: Contribution of injured and uninjured dorsal root ganglion neurons to pain behavior and the changes in gene expression following chronic constriction injury of the sciatic nerve in rats. Pain 101: 65-77, 2003
    • (2003) Pain , vol.101 , pp. 65-77
    • Obata, K.1    Yamanaka, H.2    Fukuoka, T.3    Dai, Y.4    Tokunaga, A.5
  • 5
    • 33645972629 scopus 로고    scopus 로고
    • BDNF in sensory neurons and chronic pain
    • Obata K, Noguchi K: BDNF in sensory neurons and chronic pain. Neurosci Res 55: 1-10, 2006
    • (2006) Neurosci Res , vol.55 , pp. 1-10
    • Obata, K.1    Noguchi, K.2
  • 6
    • 30144445704 scopus 로고    scopus 로고
    • The effect of site and type of nerve injury on the expression of brain-derived neurotrophic factor in the dorsal root ganglion and on neuropathic pain behavior
    • Obata K, Yamanaka H, Kobayashi K, Dai Y, Mizushima T, et al: The effect of site and type of nerve injury on the expression of brain-derived neurotrophic factor in the dorsal root ganglion and on neuropathic pain behavior. Neuroscience 137: 961-970, 2006
    • (2006) Neuroscience , vol.137 , pp. 961-970
    • Obata, K.1    Yamanaka, H.2    Kobayashi, K.3    Dai, Y.4    Mizushima, T.5
  • 7
    • 1642357495 scopus 로고    scopus 로고
    • MAPK activation in nociceptive neurons and pain hypersensitivity
    • Obata K, Noguchi K: MAPK activation in nociceptive neurons and pain hypersensitivity. Life Sci 74: 2643-2653, 2004
    • (2004) Life Sci , vol.74 , pp. 2643-2653
    • Obata, K.1    Noguchi, K.2
  • 8
    • 44449169528 scopus 로고    scopus 로고
    • Regulation of ERK in sensory neurons during inflammation
    • eds Schmidt RF, Willis WD, Springer-Verlag, Heidelberg, Germany, in press
    • Obata K, Dai Y, Noguchi K: Regulation of ERK in sensory neurons during inflammation. In: Encyclopedic Reference of Pain, (eds) Schmidt RF, Willis WD, Springer-Verlag, Heidelberg, Germany, 2007, in press
    • (2007) Encyclopedic Reference of Pain
    • Obata, K.1    Dai, Y.2    Noguchi, K.3
  • 9
    • 0036710293 scopus 로고    scopus 로고
    • Expression of neurotrophic factors in the dorsal root ganglion in a rat model of lumbar disc herniation
    • Obata K, Tsujino H, Yamanaka H, Dai Y, Fukuoka T, et al: Expression of neurotrophic factors in the dorsal root ganglion in a rat model of lumbar disc herniation. Pain 99: 121-132, 2002
    • (2002) Pain , vol.99 , pp. 121-132
    • Obata, K.1    Tsujino, H.2    Yamanaka, H.3    Dai, Y.4    Fukuoka, T.5
  • 10
    • 2942520147 scopus 로고    scopus 로고
    • Contribution of degeneration of motor and sensory fibers to pain behavior and the changes in neurotrophic factors in rat dorsal root ganglion
    • Obata K, Yamanaka H, Dai Y, Mizushima T, Fukuoka T, et al: Contribution of degeneration of motor and sensory fibers to pain behavior and the changes in neurotrophic factors in rat dorsal root ganglion. Exp Neurol 188: 149-160, 2004
    • (2004) Exp Neurol , vol.188 , pp. 149-160
    • Obata, K.1    Yamanaka, H.2    Dai, Y.3    Mizushima, T.4    Fukuoka, T.5
  • 11
    • 2942685267 scopus 로고    scopus 로고
    • Activation of extracellular signal-regulated protein kinase in the dorsal root ganglion following inflammation near the nerve cell body
    • Obata K, Yamanaka H, Dai Y, Mizushima T, Fukuoka T, et al: Activation of extracellular signal-regulated protein kinase in the dorsal root ganglion following inflammation near the nerve cell body. Neuroscience 126: 1011-1021, 2004
    • (2004) Neuroscience , vol.126 , pp. 1011-1021
    • Obata, K.1    Yamanaka, H.2    Dai, Y.3    Mizushima, T.4    Fukuoka, T.5
  • 12
    • 0032188750 scopus 로고    scopus 로고
    • Change in mRNAs for neuropeptides and the GABA (A) receptor in dorsal root ganglion neurons in a rat experimental neuropathic pain model
    • Fukuoka T, Tokunaga A, Kondo E, Miki K, Tachibana T, et al: Change in mRNAs for neuropeptides and the GABA (A) receptor in dorsal root ganglion neurons in a rat experimental neuropathic pain model. Pain 78: 13-26, 1998
    • (1998) Pain , vol.78 , pp. 13-26
    • Fukuoka, T.1    Tokunaga, A.2    Kondo, E.3    Miki, K.4    Tachibana, T.5
  • 13
    • 0000651996 scopus 로고    scopus 로고
    • The role of neighboring intact dorsal root ganglion neurons in a rat neuropathic pain model
    • eds Devor M, Rowbotham MC, Wiesenfeld-Hallin Z, IASP Press, Seattle, WA
    • Fukuoka T, Tokunaga A, Kondo E, Noguchi K: The role of neighboring intact dorsal root ganglion neurons in a rat neuropathic pain model. In: Proceedings of the 9th World Congress on Pain, (eds) Devor M, Rowbotham MC, Wiesenfeld-Hallin Z, IASP Press, Seattle, WA, 1999, pp137-146
    • (1999) Proceedings of the 9th World Congress on Pain , pp. 137-146
    • Fukuoka, T.1    Tokunaga, A.2    Kondo, E.3    Noguchi, K.4
  • 14
    • 0035400009 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor increases in the uninjured dorsal root ganglion neurons in selective spinal nerve ligation model
    • Fukuoka T, Kondo E, Dai Y, Hashimoto N, Noguchi K: Brain-derived neurotrophic factor increases in the uninjured dorsal root ganglion neurons in selective spinal nerve ligation model. J Neurosci 21: 4891-4900, 2001
    • (2001) J Neurosci , vol.21 , pp. 4891-4900
    • Fukuoka, T.1    Kondo, E.2    Dai, Y.3    Hashimoto, N.4    Noguchi, K.5
  • 15
    • 33751089066 scopus 로고    scopus 로고
    • Suppression of the p75 neurotrophin receptor in uninjured sensory neurons reduces neuropathic pain after nerve injury
    • Obata K, Katsura H, Sakurai J, Kobayashi K, Yamanaka H, et al: Suppression of the p75 neurotrophin receptor in uninjured sensory neurons reduces neuropathic pain after nerve injury. J Neurosci 26: 11974-11986, 2006
    • (2006) J Neurosci , vol.26 , pp. 11974-11986
    • Obata, K.1    Katsura, H.2    Sakurai, J.3    Kobayashi, K.4    Yamanaka, H.5
  • 16
    • 24644462327 scopus 로고    scopus 로고
    • TRPA1 induced in sensory neurons contributes to cold hyperalgesia after inflammation and nerve injury
    • Obata K, Katsura H, Mizushima T, Yamanaka H, Kobayashi K, et al: TRPA1 induced in sensory neurons contributes to cold hyperalgesia after inflammation and nerve injury. J Clin Invest 115: 2393-2401, 2005
    • (2005) J Clin Invest , vol.115 , pp. 2393-2401
    • Obata, K.1    Katsura, H.2    Mizushima, T.3    Yamanaka, H.4    Kobayashi, K.5
  • 17
    • 33746083982 scopus 로고    scopus 로고
    • Antisense knock down of TRPA1, but not TRPM8, alleviates cold hyperalgesia after spinal nerve ligation in rats
    • Katsura H, Obata K, Mizushima T, Yamanaka H, Kobayashi K, et al: Antisense knock down of TRPA1, but not TRPM8, alleviates cold hyperalgesia after spinal nerve ligation in rats. Exp Neurol 200: 112-123, 2006
    • (2006) Exp Neurol , vol.200 , pp. 112-123
    • Katsura, H.1    Obata, K.2    Mizushima, T.3    Yamanaka, H.4    Kobayashi, K.5
  • 18
  • 19
    • 34547889515 scopus 로고    scopus 로고
    • Roles of extracellular signal-regulated protein kinases 5 in spinal microglia and primary sensory neurons for neuropathic pain
    • Obata K, Katsura H, Mizushima T, Sakurai J, Kobayashi K, et al: Roles of extracellular signal-regulated protein kinases 5 in spinal microglia and primary sensory neurons for neuropathic pain. J Neurochem 102: 1569-1584, 2007
    • (2007) J Neurochem , vol.102 , pp. 1569-1584
    • Obata, K.1    Katsura, H.2    Mizushima, T.3    Sakurai, J.4    Kobayashi, K.5
  • 20
    • 10844241535 scopus 로고    scopus 로고
    • Differential activation of MAPK in injured and uninjured DRG neurons following chronic constriction injury of the sciatic nerve in rats
    • Obata K, Yamanaka H, Dai Y, Mizushima T, Fukuoka T, et al: Differential activation of MAPK in injured and uninjured DRG neurons following chronic constriction injury of the sciatic nerve in rats. Eur J Neurosci 20: 2881-2895, 2004
    • (2004) Eur J Neurosci , vol.20 , pp. 2881-2895
    • Obata, K.1    Yamanaka, H.2    Dai, Y.3    Mizushima, T.4    Fukuoka, T.5
  • 21
    • 0035076820 scopus 로고    scopus 로고
    • Differential regulation of P2X (3) mRNA expression by peripheral nerve injury in intact and injured neurons in the rat sensory ganglia
    • Tsuzuki K, Kondo E, Fukuoka T, Dai Y, Tsujino H, et al: Differential regulation of P2X (3) mRNA expression by peripheral nerve injury in intact and injured neurons in the rat sensory ganglia. Pain 91: 351-360, 2001
    • (2001) Pain , vol.91 , pp. 351-360
    • Tsuzuki, K.1    Kondo, E.2    Fukuoka, T.3    Dai, Y.4    Tsujino, H.5
  • 22
    • 0036711435 scopus 로고    scopus 로고
    • VR1, but not P2X (3), increases in the spared L4 DRG in rats with L5 spinal nerve ligation
    • Fukuoka T, Tokunaga A, Tachibana T, Dai Y, Yamanaka H, et al: VR1, but not P2X (3), increases in the spared L4 DRG in rats with L5 spinal nerve ligation. Pain 99: 111-120, 2002
    • (2002) Pain , vol.99 , pp. 111-120
    • Fukuoka, T.1    Tokunaga, A.2    Tachibana, T.3    Dai, Y.4    Yamanaka, H.5
  • 23
    • 33947517578 scopus 로고    scopus 로고
    • Tissue type plasminogen activator induced in rat dorsal horn astrocytes contributes to mechanical hypersensitivity following dorsal root injury
    • Kozai T, Yamanaka H, Dai Y, Obata K, Kobayashi K, et al: Tissue type plasminogen activator induced in rat dorsal horn astrocytes contributes to mechanical hypersensitivity following dorsal root injury. Glia 55: 595-603, 2007
    • (2007) Glia , vol.55 , pp. 595-603
    • Kozai, T.1    Yamanaka, H.2    Dai, Y.3    Obata, K.4    Kobayashi, K.5
  • 24
    • 33748279280 scopus 로고    scopus 로고
    • Activation of Src-family kinases in spinal microglia contributes to mechanical hypersensitivity after nerve injury
    • Katsura H, Obata K, Mizushima T, Sakurai J, Kobayashi K, et al: Activation of Src-family kinases in spinal microglia contributes to mechanical hypersensitivity after nerve injury. J Neurosci 26: 8680-8690, 2006
    • (2006) J Neurosci , vol.26 , pp. 8680-8690
    • Katsura, H.1    Obata, K.2    Mizushima, T.3    Sakurai, J.4    Kobayashi, K.5
  • 25
    • 0028800179 scopus 로고
    • Substance P induced by peripheral nerve injury in primary afferent sensory neurons and its effect on dorsal column nucleus neurons
    • Noguchi K, Kawai Y, Fukuoka T, Senba E, Miki K: Substance P induced by peripheral nerve injury in primary afferent sensory neurons and its effect on dorsal column nucleus neurons. J Neurosci 15: 7633-7643, 1995
    • (1995) J Neurosci , vol.15 , pp. 7633-7643
    • Noguchi, K.1    Kawai, Y.2    Fukuoka, T.3    Senba, E.4    Miki, K.5
  • 26
    • 0342275181 scopus 로고    scopus 로고
    • Calcitonin gene-related peptide increase in the rat spinal dorsal horn and dorsal column nucleus following peripheral nerve injury: Up-regulation in a subpopulation of primary afferent sensory neurons
    • Miki K, Fukuoka T, Tokunaga A, Noguchi K: Calcitonin gene-related peptide increase in the rat spinal dorsal horn and dorsal column nucleus following peripheral nerve injury: up-regulation in a subpopulation of primary afferent sensory neurons. Neuroscience 82: 1243-1252, 1998
    • (1998) Neuroscience , vol.82 , pp. 1243-1252
    • Miki, K.1    Fukuoka, T.2    Tokunaga, A.3    Noguchi, K.4
  • 27
    • 17344394536 scopus 로고    scopus 로고
    • Responses of dorsal column nuclei neurons in rats with experimental mononeuropathy
    • Miki K, Iwata K, Tsuboi Y, Sumino R, Fukuoka T, et al: Responses of dorsal column nuclei neurons in rats with experimental mononeuropathy. Pain 76: 407-415, 1998
    • (1998) Pain , vol.76 , pp. 407-415
    • Miki, K.1    Iwata, K.2    Tsuboi, Y.3    Sumino, R.4    Fukuoka, T.5
  • 28
    • 0033961211 scopus 로고    scopus 로고
    • Dorsal column-thalamic pathway is involved in thalamic hyperexcitability following peripheral nerve injury: A lesion study in rats with experimental mononeuropathy
    • Miki K, Iwata K, Tsuboi Y, Morimoto T, Kondo E, et al: Dorsal column-thalamic pathway is involved in thalamic hyperexcitability following peripheral nerve injury: a lesion study in rats with experimental mononeuropathy. Pain 85: 263-271, 2000
    • (2000) Pain , vol.85 , pp. 263-271
    • Miki, K.1    Iwata, K.2    Tsuboi, Y.3    Morimoto, T.4    Kondo, E.5
  • 29
    • 0032745022 scopus 로고    scopus 로고
    • Excitability of spinal cord and gracile nucleus neurons in rats with chronically injured sciatic nerve examined by c-fos expression
    • Tokunaga A, Kondo E, Fukuoka T, Miki K, Dai Y, et al: Excitability of spinal cord and gracile nucleus neurons in rats with chronically injured sciatic nerve examined by c-fos expression. Brain Res 847: 321-331, 1999
    • (1999) Brain Res , vol.847 , pp. 321-331
    • Tokunaga, A.1    Kondo, E.2    Fukuoka, T.3    Miki, K.4    Dai, Y.5
  • 30
    • 1542269755 scopus 로고    scopus 로고
    • Enhancement of stimulation-induced ERK activation in the spinal dorsal horn and gracile nucleus neurons in rats with peripheral nerve injury
    • Wang H, Dai Y, Fukuoka T, Yamanaka H, Obata K, et al: Enhancement of stimulation-induced ERK activation in the spinal dorsal horn and gracile nucleus neurons in rats with peripheral nerve injury. Eur J Neurosci 19: 884-890, 2004
    • (2004) Eur J Neurosci , vol.19 , pp. 884-890
    • Wang, H.1    Dai, Y.2    Fukuoka, T.3    Yamanaka, H.4    Obata, K.5
  • 31
    • 1642499176 scopus 로고    scopus 로고
    • Tissue plasminogen activator in primary afferents induces dorsal horn excitability and pain response after peripheral nerve injury
    • Yamanaka H, Obata K, Fukuoka T, Dai Y, Kobayashi K, et al: Tissue plasminogen activator in primary afferents induces dorsal horn excitability and pain response after peripheral nerve injury. Eur J Neurosci 19: 93-102, 2004
    • (2004) Eur J Neurosci , vol.19 , pp. 93-102
    • Yamanaka, H.1    Obata, K.2    Fukuoka, T.3    Dai, Y.4    Kobayashi, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.