Antenatal indomethacin is more likely associated with spontaneous intestinal perforation rather than NEC

American Journal of Obstetrics and Gynecology

Volumn 198, Issue 6, 2008, Pages 725-

  Gordon, Phillip V ^a   Swanson, Jonathan R ^b   Clark, Reese ^c  

^a OCHSNER CLINIC FOUNDATION   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

^c Pediatrix Medical Group Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROCORTISONE; INDOMETACIN; NITRIC OXIDE SYNTHASE; STEROID;

BIRTH WEIGHT; CHORIOAMNIONITIS; HUMAN; ILEUM; INTESTINE PERFORATION; LETTER; NECROTIZING ENTEROCOLITIS; NONHUMAN; PREMATURITY; PRENATAL EXPOSURE; PRENATAL PERIOD; PRIORITY JOURNAL; RISK FACTOR;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ENTEROCOLITIS, NECROTIZING; HUMANS; INDOMETHACIN; INTESTINAL PERFORATION; RISK FACTORS;

EID: 44449139459     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajog.2008.01.026     Document Type: Letter

References (4)

1. Amin S.B., Sinkin R.A., and Glantz J.C. Metaanalysis of the effect of antenatal indomethacin on neonatal outcomes. Am J Obstet Gynecol 197 (2007) 486.e1-486.e10
2. Attridge J.T., Clark R., Walker M.W., and Gordon P.V. New insights into spontaneous intestinal perforation using a national data set: (1) SIP is associated with early indomethacin exposure. J Perinatol 26 (2006) 93-99
3. Watterberg K.L., Gerdes J.S., Cole C.H., et al. Prophylaxis of early adrenal insufficiency to prevent bronchopulmonary dysplasia: A multicenter trial. Pediatrics 114 (2004) 1649-1657
4. Gordon P.V., Herman A.C., Marcinkiewicz Gaston B.M., Laubach V.E., and Aschner J.L. A neonatal mouse model of intestinal perforation: investigating the harmful synergism between glucocorticoids and indomethacin. J Pediatr Gastroenterol Nutr 45 (2007) 509-519