A double-blind placebo-controlled study to evaluate the safety and efficacy of L-2-oxothiazolidine-4-carboxylic acid in the treatment of patients with acute respiratory distress syndrome

Critical Care Medicine

Volumn 36, Issue 3, 2008, Pages 782-788

  Morris, Peter E ^a   Papadakos, Peter ^b   Russell, James A ^c   Wunderink, Richard ^d   Schuster, Daniel P ^e   Truwit, Jonathon D ^f   Vincent, Jean Louis ^g   Bernard, Gordon R ^h  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF ROCHESTER   (United States)

^c ST PAUL S HOSPITAL   (Canada)

^d CASE WESTERN RESERVE UNIVERSITY   (United States)

^e WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF VIRGINIA   (United States)

^g ERASME HOSPITAL   (Belgium)

^h VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Acute respiratory distress syndrome; Glutathione; Oxothiazolidine 4 carboxylic acid

Indexed keywords

2 OXO 4 THIAZOLIDINECARBOXYLIC ACID; PLACEBO; 2-OXOTHIAZOLIDINE-4-CARBOXYLIC ACID; PYROGLUTAMIC ACID; THIAZOLIDINE DERIVATIVE;

ADULT RESPIRATORY DISTRESS SYNDROME; ARTERIAL OXYGEN SATURATION; ARTICLE; ARTIFICIAL VENTILATION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; DRUG WITHDRAWAL; FEMALE; HUMAN; HYPERNATREMIA; LUNG INFILTRATE; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTICENTER STUDY; PNEUMOTHORAX; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SURVIVAL TIME; THORAX RADIOGRAPHY; TREATMENT DURATION; TREATMENT RESPONSE; ADOLESCENT; ADULT; AGED; MIDDLE AGED;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE; MIDDLE AGED; PYRROLIDONECARBOXYLIC ACID; RESPIRATORY DISTRESS SYNDROME, ADULT; THIAZOLIDINES;

EID: 44449111361     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0B013E318164E7E4     Document Type: Article

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