Viper metalloproteinase (Agkistrodon halys Pallas) with antimicrobial activity against multi-drug resistant human pathogens

Journal of Cellular Physiology

Volumn 216, Issue 1, 2008, Pages 54-68

  Samy, Ramar Perumal ^a   Gopalakrishnakone, Ponnampalam ^a   Chow, Vincent T K ^a   Ho, Bow ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

METALLOPROTEINASE; METHIONYLISOLEUCYLGLUTAMINYLVALYLLEUCYLLEUCYLVALYLTHREONYL ISOLEUCYLCYSTEINYLLEUCYLALANYLVALYLPHENYLALANYLPROLYLTYROSYL GLUTAMINYLGLYCYLSERYLSERYLISOLEUCYLISOLEUCYLLEUCYLGLUTAMYLSERINE; POLYPEPTIDE; ANTIINFECTIVE AGENT; SNAKE VENOM;

AGKISTRODON HALYS; AMINO ACID SEQUENCE; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIOSTASIS; BURKHOLDERIA PSEUDOMALLEI; CONTROLLED STUDY; CYTOTOXICITY; ENTEROBACTER AEROGENES; ESCHERICHIA COLI; HUMAN; HUMAN CELL; MINIMUM INHIBITORY CONCENTRATION; MONOCYTE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEUS MIRABILIS; PROTEUS VULGARIS; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; AGKISTRODON; ANIMAL; BACTERIUM; CELL LINE; DOSE RESPONSE; DRUG EFFECT; ENZYMOLOGY; GENETICS; METABOLISM; MICROBIOLOGICAL EXAMINATION; MOLECULAR GENETICS; MULTIDRUG RESISTANCE; SEQUENCE ALIGNMENT; ULTRASTRUCTURE;

BACTERIA (MICROORGANISMS); BURKHOLDERIA PSEUDOMALLEI; ENTEROBACTER AEROGENES; ESCHERICHIA COLI; GLOYDIUS HALYS; PROTEUS MIRABILIS; PROTEUS VULGARIS; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; VIPERIDAE; VIPERINAE;

AGKISTRODON; AMINO ACID SEQUENCE; ANIMALS; ANTI-INFECTIVE AGENTS; BACTERIA; CELL LINE; CROTALID VENOMS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, MULTIPLE, BACTERIAL; HUMANS; METALLOPROTEASES; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; SEQUENCE ALIGNMENT;

EID: 44449102736     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.21373     Document Type: Article

References (47)

1. Bauer AW, Kirby WM, Sherris JC, Turck M. 1966. Antibiotic susceptibility testing by a standardized single disk method. Am J Clin Pathol 45:493-496.
2. Bessalle R, Gorea A, Shalit I, Metzger JW, Dass C, Desiderio DM, Fridkin M. 1993. Structure-function studies of amphiphilic antibacterial peptides. J Med Chem 36:1203-1209.
3. Bjarnason JB, Fox JW. 1994. Hemorrhagic metalloproteinases from snake venoms. Pharmacol Ther 62:325-372.
4. Bode W, Gomis-Rüth FX, Stockler W. 1993. Astacins, serralysins, snake venom and matrix metalloproteinases exhibit identical zinc-binding environments (HEXX-HXXGXXH and Met-turn) and topologies and should be grouped into a common family, the 'metzincins'. FEBS Lett 331:134-140.
5. Bradford MM. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Ann Biochem 72:248-254.
6. Brogden KA. 2005. Antimicrobial peptides: Pore formers or metabolic inhibitors in bacteria? Nat Rev Microbiol 3:238-250.
7. Dathe M, Schumann M, Wieprecht T, Winkler A, Beyermann M, Krause E, Matsuzaki K, Murase O, Bienert M. 1996. Peptide helicity and membrane surface charge modulate the balance of electrostatic and hydrophobic interactions with lipid bilayers and biological membranes. Biochemistry 35:12612-12622.
8. Elsinghorst EA. 1994. Measurement of invasion by gentamicin reistance. Methods Enzymol 236:405-420.
9. Fini C, Palmerini CA, Damiani P, Stochaj U, Mannherz HG, Floridi A. 1990. 5′-nucleotidase from bull seminal plasma, chicken gizzard and snake venom is a zinc metalloprotein. Biochim Biophys Acta 1038:18-22.
10. Fox JW, Long C. 1998. ADAMs/MDC family of proteins and their relationships to the snake venom metalloproteinases. In: Bayley GS, editor. Enzymes from snake venom. Fort Colli, CO: Alaken. pp 151-178.
11. Fox JW, Serrano MT. 2005. Structure considerations of the snake venom metallproteinases, key members of the M12 reprolysin family of metalloproteinases. Toxicon 45:969-985.
12. Gallo RL, Murkami M, Ohtaje T, Zaiou M. 2002. Biology and clinical relevance of naturally occurring antimicrobial peptides. J Allergy Clin Immunol 110:823-831.
13. Ganz T. 2003. Defensins: Antimicrobial peptides of innate immunity. Nat Rev Immunol 3:710-720.
14. Giesbrecht P, Kersten T, Maidhof H, Wecke J. 1998. Staphylococcal cell wall: Morphogenesis and fatal variations in the presence of penicillin. Microbiol Mol Biol Rev 62:1371-1414.
15. 2 from the venom of Agkistrodon halys pallas. Toxicon 30:516.
16. Hancock RE, Scoot MG. 2000. The role of antimicrobial peptides in animal defences. Proc Natl Acad Sci USA 97:8856-5861.
17. Hancock RE, Fall T, Brown M. 1995. Cationic bactericidal peptides. Adv Microb Physiol 37:135-175.
18. Hite LA, Jia LG, Bjarnason JB, Fox JW. 1994. cDNA sequences for four snake venom metalloproteinases: Structure, classification and their relationship to mammalian reproductive proteins. Arch Biophys 308:182-191.
19. Hodgkin EE, Gillman IC, Gilbert RJ. 1994. Retrospective analysis of a secondary structure prediction: The catalytic domain of matrix metalloproteinases. Protein Sci 3:984-986.
20. Kamiguti AS, Zuzel M, Theakston RDG. 1998. Snake venom metalloproteinases and disintegrins: Interactions with cells. Braz J Med Biol Res 31:853-862.
21. 2. J Biol Chem 277:5849-5857.
22. Krijgsveld J, Zaat SAJ, Meeldijk J, Van Veelan PA, Fang G, Poolman B, Brandt E, Ehlert JE, Kuijpers AJ, Engber GHM, Feijen J, Dankert J. 2000. Thrombocidins, microbicidal proteins from human blood platelets, are C-terminal deletion products of CXC-chemokines. J Biol Chem 226:497-509.
23. Laemmli UK. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage. Nature 227:680-685.
24. Liu Q, Xu W, Cheng X, Jin G, Shen X, Lou H, Liu J. 1999. Molecular cloning and sequence analysis of cDNA encoding haemorrhagic toxin acutolysin A from Agkistrodon acutus. Toxicon 37:1539-1548.
25. Liu JW, Du XY, Liu P, Chen X, Xu JM, Wu XF, Zhou YC. 2000. Purification, characterization, and cDNA sequence of halysetin, a disintegrin-like/cysteine- rich protein from the venom of Agkistradon halys Pallas. Biochem Biophys Res Commun 278:112-118.
26. Mandelbaum FR, Ractü AP, Asswauaw MT. 1982. Isolation and characterization of a proteolytic enzyme from the venom of the snake Bothrops jararota (jararaca). Toxicon 20:955-972.
27. Matsuzaki K. 1998. Magainins as paradigm for the mode of action of pore forming polypetides. Biochim Biophys Acta 1376:391-400.
28. Mebs D, Panholze F. 1982. Isolation of a hemorrhagic principle from Bitis arietans (puff adder) snake venom. Toxicon 20:509-512.
29. Motizuki M, Itoh T, Satoh T, Yokota S, Yamada M, Shimamura S, Samejima T, Tsurugi K. 1999. Lipid-binding and antimicrobial properties of synthetic peptides of bovine apolipoprotein A-II. Biochem J 342:215-221.
30. National Committee for Clinical Laboratory Standards. 1997a Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria that Grow Aerobically. Approved Standard M7-A4. National Committee for Clinical Standards. Wayne Pennsylvania. January 1997.
31. National Committee for Clinical Laboratory Standards. 1997b Performance Standards for Antimicrobial Disk Susceptibility Tests: Approved Standard M2-A6. National Committee for Clinical Standards. Wayne Pennsylvania, January 1997.
32. 2 from Agkistrodon piscivorus piscivorus snake venom: Synthetic C-terminal peptides from Lys49. but not from Asp49 myotoxins, exert membrane-damaging activities. Toxicon 39:1587-1594.
33. Pachiappan A, Thwin MM, Manikandan J, Gopalakrishnakone P. 2005. Glial inflammation and neurodegeneration induced by candoxin. a novel neurotoxin from Bungarus candidus venom: Global gene expression analysis using microarray. Toxicon 46:883-899.
34. Park CB, Kim HS, Kim SC. 1998. Mechanism of action of the antimicrobial peptide buforin II: Buforin II kills microorganisms by penetrating the cell membrane and inhibiting cellular functions. Biochem Biophys Res Commun 224:253-257.
35. Pirkle H. 1998. Thrombin-like enzymes from snake venoms: An updated inventory. Thromb Haemost 79:675-683.
36. Pretzer D, Schulteis BS, Smith CD, Vander Velde DG, Mitchell JW, Manning M. 1993. Fibrolase, a fibrinolytic protein from snake venom. In: Pearlman R, Wang YJ, editors. Pharmaceutical biotechnology Vol. 5. New York: Plenum Press. pp 287-314.
37. Randolph A, Chamberlain SH, Chu HL, Retzios AD, Markland FS, Jr., Masiarz FR. 1992. Amino acid sequence of fibrolase, a direct-acting fibrinolytic enzyme from Agkistrodon eontortrix contortrix venom. Protein Sci 1:590-600.
38. Sakai J, Zhang S, Chen H, Atsumi F, Matsui T, Shiono H, Sanada S, Okada T. 2006. Primary structure of a thrombin-like serine protease, kangshuanmei, from the venom of Agkistrodon halys brevicaudus stejneger. Toxicon 48:313-322.
39. Silva FP, Jr., De-Simone SG. 2004. S1 subsite in snake venome thrombin-like enzymes: Can S1 subsite lipophilicity be used to sort binding affinities of trypsin-like enzyme to small-molecule inhibitors? Bioorg Med Chem 12:2571-2587.
40. Trummal K, Tonismagi K, Siigur E, Aaspollu A, Lopp A, Sillat T, Saat R, Kasak L, Tammiste I, Kogerman P, Kalkkinen N, Siigur J. 2005. A novel metalloproteinase from Vipera lebetina venom induces human endothelial cell apoptosis. Toxicon 46:46-61.
41. Wan SG, Jin Y, Lee WH, Zhang Y. 2006. A snake venom metalloproteinase that inhibited cell proliferation and induced morphological changes of ECV304 cells. Toxicon 15: 47: 480-489.
42. Wang SH, Shen XC, Yang GZ, Wu XF. 2003. cDNA cloning and characterization of Agkistin, a new metalloproteinases from Agkistrodon halys. Biochem Biophys Res Commun 301:298-303.
43. Watters AA, Jones RN, Leeds JA, Denys G, Sader HS, Fritsche TR. 2006. Antimicrobial activity of a novel peptide deformylase inhibitor, LBM415, tested against respiratory tract and cutaneous infection pathogens: A global surveillance report (2003-2004). J Antimicrob Chemother 57:914-923.
44. You WK, Seo HJ, Chung KH, Kim DS. 2003. A novel metalloproteinases from Gloydius halys venom induces enthothelial cell apoptosis through its protease and disintegrin-like domains. J Biochem (Tokyo) 134:739-749.
45. Zasloff M. 2002. Antimicrobial peptides of multicellular organisms. Nature 415:389-395.
46. Zhang S, Ma B, Sakai J, Shiono H, Matsui T, Sugie I, Okada T. 2001. Characterization of a thrombin-like serine protease, kangshuanmei, isolated from the venom of a Chinese snake, Agkistrodon halys brevicaudus stejnerger. J Nat Toxins 10:221-238.
47. 2 from Agkistrodon halys Pallas: Implications for its association, hemolytic and anticoagulant activities. Toxicon 38:901-916.