Serum prolidase and IGF-1 as non-invasive markers of hepatic fibrosis during four different periods after bile-duct ligation in rats

Digestive Diseases and Sciences

Volumn 53, Issue 7, 2008, Pages 1938-1945

  Tarçin, Orhan ^a,b   Gedik, Nursal ^c   Karakoyun, Berna ^d   Tahan, Veysel ^d   Sood, Gagan ^e   Çelikel, Çiǧdem ^d   Tözün, Nurdan ^d  

^a Gumussuyu Military Hospital   (Turkey)

^b Kasimpaşa Military Hospital ^*  (Turkey)

^c KASIMPASA MILITARY HOSPITAL   (Turkey)

^d MARMARA UNIVERSITY   (Turkey)

^e University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Bile duct ligation; Collagen; Hepatic fibrosis; IGF 1; Prolidase; Serum marker

Indexed keywords

COLLAGEN; PROLINE DIPEPTIDASE; SOMATOMEDIN C;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE DUCT LIGATION; CONTROLLED STUDY; DISEASE COURSE; ENZYME ACTIVITY; HISTOPATHOLOGY; LIVER FIBROSIS; LIVER INJURY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BILE DUCTS; BIOLOGICAL MARKERS; DIPEPTIDASES; INSULIN-LIKE GROWTH FACTOR I; LIGATION; LIVER CIRRHOSIS; MALE; RATS; RATS, WISTAR; REGRESSION ANALYSIS; STATISTICS, NONPARAMETRIC;

EID: 44449099772     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10620-007-0073-1     Document Type: Article

References (39)

1. Knittel T, Kobold D, Piscaglia F, Saile B, Neubauer K, Mehde M, Timpl R, Ramadori G (1999) Localization of liver myofibroblasts and hepatic stellate cells in normal and diseased rat livers: distinct roles of (myo-) fibroblast subpopulations in hepatic tissue repair. Histochem Cell Biol 112:387-401
2. Canbay A, Friedman S, Gores GJ (2004) Apoptosis: the nexus of liver injury and fibrosis. Hepatology 39:273-278
3. Friedman SL (2003) Liver fibrosis - from bench to bedside. J Hepatol 38(Suppl 1):S38-S53
4. Schuppan D, Schmid M, Somasundaram R, Ackermann R, Ruehl M, Nakamura T, Riecken EO (1998) Collagens in the liver extracellular matrix bind hepatocyte growth factor. Gastroenterology 114:139-152
5. Bataller R, North KE, Brenner DA (2003) Genetic polymorphisms and the progression of liver fibrosis: a critical appraisal. Hepatology 37:493-503
6. Afdhal NH, Nunes D (2004) Evaluation of liver fibrosis: a concise review. Am J Gastroenterol 99:1160-1174
7. Forns X, Ampurdanes S, Sanchez-Tapias JM, Guilera M, Sans M, Sanchez-Fueyo A, Quinto L, Joya P, Bruguera M, Rodes J (2001) Long-term follow-up of chronic hepatitis C in patients diagnosed at a tertiary-care center. J Hepatol 35:265-271
8. Yano M, Kumada H, Kage M, Ikeda K, Shimamatsu K, Inoue O, Hashimoto E, Lefkowitch JH, Ludwig J, Okuda K (1996) The long-term pathological evolution of chronic hepatitis C. Hepatology 23:1334-1340
9. Curry MP (2005) Serum markers of hepatic fibrosis. Up-to-date 2005; Online 13.1:1-12
10. Poynard T, Munteanu M, Imbert-Bismut F, Charlotte F, Thabut D, Le Calvez S, Messous D, Thibault V, Benhamou Y, Moussalli J, Ratziu V (2004) Prospective analysis of discordant results between biochemical markers and biopsy in patients with chronic hepatitis C. Clin Chem 50:1344-1355
11. Kobayashi M, Shimizu S (1999) Cobalt proteins. Eur J Biochem 261:1-9
12. Bazan JF, Weaver LH, Roderick SL, Huber R, Matthews BW (1994) Sequence and structure comparison suggest that methionine aminopeptidase, prolidase, aminopeptidase P, and creatinase share a common fold. Proc Natl Acad Sci USA 91:2473-2477
13. Guszczyn T, Sobolewski K (2004) Deregulation of collagen metabolism in human stomach cancer. Pathobiology 71:308-313
14. Brosset B, Myara I, Fabre M, Lemonnier A (1988) Plasma prolidase and prolinase activity in alcoholic liver disease. Clin Chim Acta 175:291-295
15. Abraham P, Wilfred G, Ramakrishna B (2000) Plasma prolidase may be an index of liver fibrosis in the rat. Clin Chim Acta 295:199-202
16. Kaymaz O, Gultepe GM, Avsar K (1999) Serum prolidase activity in diagnosis of hepatic fibrosis and following of interferon therapy, and optimization of the method. XV. National Biochemistry Congress, Abstract Book. Ankara. XV National Biochemistry Congress, Abstract Book Ankara
17. Gültepe M, Özcan A, Altin M, Öztürk G, Demirci M (1994) Evaluation of the response of hepatic fibrosis to colchicine treatment by estimating serum prolidase activity and procollagen III amino terminal propeptide levels. Turk J Med Sci 20:99-104
18. Sara V R, Hall K (1990) Insulin-like growth factors and their binding proteins. Physiol Rev 70:591-614
19. Schwander JC, Hauri C, Zapf J, Froesch ER (1983) Synthesis and secretion of insulin-like growth factor and its binding protein by the perfused rat liver: dependence on growth hormone status. Endocrinology 113:297-305
20. Blomsma MC, de Knegt RJ, Dullaart RP, Jansen PL (1997) Insulin-like growth factor-I in liver cirrhosis. J Hepatol 27:1133-1138
21. Moller S, Juul A, Becker U, Flyvbjerg A, Skakkebaek NE, Henriksen JH (1995) Concentrations, release, and disposal of insulin-like growth factor (IGF)-binding proteins (IGFBP), IGF-I, and growth hormone in different vascular beds in patients with cirrhosis. J Clin Endocrinol Metab 80:1148-1157
22. Yoshida S, Nio M, Hayashi Y, Ohi R, Kawamura I, Goto T (2003) Serum insulinlike growth factor-I in biliary atresia. J Pediatr Surg 38:211-215
23. Kountouras J, Billing BH, Scheuer PJ (1984) Prolonged bile duct obstruction: a new experimental model for cirrhosis in the rat. Br J Exp Pathol 65:305-311
24. Lopez-De Leon A, Rojkind M (1985) A simple micromethod for collagen and total protein determination in formalin-fixed paraffin-embedded sections. J Histochem Cytochem 33:737-743
25. Myara I, Myara A, Mangeot M, Fabre M, Charpentier C, Lemonnier A (1984) Plasma prolidase activity: a possible index of collagen catabolism in chronic liver disease. Clin Chem 30:211-215
26. Gültepe M, Bolat B, Kayadibi H, Avsar K (2005) Investigation of the analytical steps of direct prolidase enzyme activity measurement. Turk J Biochem 30:p063(099)
27. Ishak K, Baptista A, Bianchi L, Callea F, De Groote J, Gudat F, Denk H, Desmet V, Korb G, Mac Sween RN et al (1995) Histological grading and staging of chronic hepatitis. J Hepatol 22:696-699
28. Afdhal NH (2004) Biopsy or biomarkers: is there a gold standard for diagnosis of liver fibrosis? Clin Chem 50:1299-1300
29. Kelleher TB, Mehta SH, Bhaskar R, Sulkowski M, Astemborski J, Thomas DL, Moore RE, Afdhal NH (2005) Prediction of hepatic fibrosis in HIV/HCV co-infected patients using serum fibrosis markers: the SHASTA index. J Hepatol 43:78-84
30. Tarcin O, Avsar K, Demirturk L, Gultepe M, Oktar BK, Ozdogan OC, Tarcin O, Baloglu H, Gurbuz AK (2003) In vivo inefficiency of pentoxifylline and interferon-alpha on hepatic fibrosis in biliary-obstructed rats: assessment by tissue collagen content and prolidase activity. J Gastroenterol Hepatol 18:437-444
31. Myara I, Miech G, Fabre M, Mangeot M, Lemonnier A (1987) Changes in prolinase and prolidase activity during CCl4 administration inducing liver cytolysis and fibrosis in rat. Br J Exp Pathol 68:7-13
32. Jiang Z, You DY, Chen XC, Wu J (1992) Monitoring of serum markers for fibrosis during CCl4-induced liver damage. Effects of anti-fibrotic agents. J Hepatol 16:282-289
33. Shahin M, Schuppan D, Waldherr R, Savolainen ER, Zalpur F, Rahman HM, el Sahly AM, Abdel Razek SM, el Ruby O, Seitz HK (1995) Circulating enzyme activities of collagen turnover and undulin in patients with various degrees of schistosomiasis and alcoholic liver cirrhosis. Hepatogastroenterology 42:22-26
34. Zuyderhoudt FM, Brugman AM, Smit JJ, de Jong L (1985) Plasma prolidase in the rat: no index of liver fibrosis. Clin Chem 31:662
35. Miltyk W, Karna E, Wolczynski S, Palka J (1998) Insulin-like growth factor I-dependent regulation of prolidase activity in cultured human skin fibroblasts. Mol Cell Biochem 189:177-183
36. Vyzantiadis T, Theodoridou S, Giouleme O, Harsoulis P, Evgenidis N, Vyzantiadis A (2003) Serum concentrations of insulin-like growth factor-I (IGF-I) in patients with liver cirrhosis. Hepatogastroenterology 50:814-816
37. Kratzsch J, Blum WF, Schenker E, Keller E (1995) Regulation of growth hormone (GH), insulin-like growth factor (IGF)I, IGF binding proteins -1, -2, -3 and GH binding protein during progression of liver cirrhosis. Exp Clin Endocrinol Diabetes 103:285-291
38. Wu YL, Ye J, Zhang S, Zhong J, Xi RP (2004) Clinical significance of serum IGF-I, IGF-II and IGFBP-3 in liver cirrhosis. World J Gastroenterol 10:2740-2743
39. Sheppard MS, Minuk GY, Bhaumick B, Bala RM (1987) Insulin-like growth factors (IGF) in liver disease: differential changes of IGF-I and IGF-II. Clin Invest Med 10:49-53