메뉴 건너뛰기




Volumn 9, Issue 2, 2004, Pages 133-137

Effects of metoprolol and amiodarone combination on heart rate, myocardial contractility and coronary flow: Study in isolated perfused rat hearts

Author keywords

Amiodarone; Coronary flow; Heart rate; Langendorff technique; Metoprolol; Myocardial contractility

Indexed keywords

AMIODARONE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; METOPROLOL;

EID: 4444383979     PISSN: 12056626     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (4)

References (37)
  • 2
    • 0027135308 scopus 로고
    • Beneficial effects of metoprolol in idiopathic dilated cardiomyopathy
    • for the Metoprolol in Dilated Cardiomyopathy (MDC) Trial study group
    • Waagstein F, Bristow MR, Swedberg K, et al, for the Metoprolol in Dilated Cardiomyopathy (MDC) Trial study group. Beneficial effects of metoprolol in idiopathic dilated cardiomyopathy. Lancet 1993;342:1441-6.
    • (1993) Lancet , vol.342 , pp. 1441-1446
    • Waagstein, F.1    Bristow, M.R.2    Swedberg, K.3
  • 3
    • 0033549290 scopus 로고    scopus 로고
    • Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in congestive Heart Failure (MERIT-HF)
    • Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in congestive Heart Failure (MERIT-HF). Lancet 1999;353:2001-7.
    • (1999) Lancet , vol.353 , pp. 2001-2007
  • 4
    • 0014829352 scopus 로고
    • The effect of amiodarone, a new anti-anginal drug, on cardiac muscle
    • Singh BN, Vaughan Williams EM. The effect of amiodarone, a new anti-anginal drug, on cardiac muscle. Br J Pharmacol 1970;39:657-67.
    • (1970) Br. J. Pharmacol. , vol.39 , pp. 657-667
    • Singh, B.N.1    Vaughan Williams, E.M.2
  • 5
    • 0033539532 scopus 로고    scopus 로고
    • Evidence-based analysis of amiodarone efficacy and safety
    • Connolly SJ. Evidence-based analysis of amiodarone efficacy and safety. Circulation 1999;100:2025-34.
    • (1999) Circulation , vol.100 , pp. 2025-2034
    • Connolly, S.J.1
  • 6
    • 0027998462 scopus 로고
    • Randomised trial of low-dose amiodarone in severe congestive heart failure
    • Grupo de Estudio de la Sobrevida en la Insuficiencia Cardiaca en Argentina (GESICA)
    • Doval HC, Nul DR, Grancelli HO, Perrone SV, Bortman GR, Curiel R. Randomised trial of low-dose amiodarone in severe congestive heart failure. Grupo de Estudio de la Sobrevida en la Insuficiencia Cardiaca en Argentina (GESICA). Lancet 1994;344:493-8.
    • (1994) Lancet , vol.344 , pp. 493-498
    • Doval, H.C.1    Nul, D.R.2    Grancelli, H.O.3    Perrone, S.V.4    Bortman, G.R.5    Curiel, R.6
  • 7
    • 0029004921 scopus 로고
    • Amiodarone in patients with congestive heart failure and asymptomatic ventricular arrhythmia. Survival Trial of Antiarrhythmic Therapy in Congestive Heart Failure
    • Singh SN, Fletcher RD, Fisher SG, et al. Amiodarone in patients with congestive heart failure and asymptomatic ventricular arrhythmia. Survival Trial of Antiarrhythmic Therapy in Congestive Heart Failure. N Engl J Med 1995;333:77-82.
    • (1995) N. Engl. J. Med. , vol.333 , pp. 77-82
    • Singh, S.N.1    Fletcher, R.D.2    Fisher, S.G.3
  • 8
    • 0032408143 scopus 로고    scopus 로고
    • Efficacy and safety of carvedilol in patients with chronic heart failure receiving concomitant amiodarone therapy
    • Australia/New Zeland Heart Failure Research Collaborative Group
    • Krum H, Shusterman N, MacMahon S, Sharpe N. Efficacy and safety of carvedilol in patients with chronic heart failure receiving concomitant amiodarone therapy. Australia/New Zeland Heart Failure Research Collaborative Group. J Card Fail 1998;4:281-8.
    • (1998) J. Card. Fail. , vol.4 , pp. 281-288
    • Krum, H.1    Shusterman, N.2    MacMahon, S.3    Sharpe, N.4
  • 9
    • 0032743258 scopus 로고    scopus 로고
    • Impact of concurrent amiodarone treatment on the tolerability and efficacy of carvedilol in patients with chronic heart failure
    • Macdonald PS, Keogh AM, Aboyoun C, Lund M, Amor R, McCaffrey D. Impact of concurrent amiodarone treatment on the tolerability and efficacy of carvedilol in patients with chronic heart failure. Heart 1999;82:589-93.
    • (1999) Heart , vol.82 , pp. 589-593
    • Macdonald, P.S.1    Keogh, A.M.2    Aboyoun, C.3    Lund, M.4    Amor, R.5    McCaffrey, D.6
  • 10
    • 0031038213 scopus 로고    scopus 로고
    • Randomised trial of effect of amiodarone on mortality in patients with left-ventricular dysfunction after recent myocardial infarction: EMIAT
    • for the European Myocardial Infarct Amiodarone Trial Investigators. (Errata in Lancet 1997;349:1180,1776)
    • Julian DG, Camm AJ, Frangin G, et al, for the European Myocardial Infarct Amiodarone Trial Investigators. Randomised trial of effect of amiodarone on mortality in patients with left-ventricular dysfunction after recent myocardial infarction: EMIAT. Lancet 1997;349:667-74. (Errata in Lancet 1997;349:1180,1776)
    • (1997) Lancet , vol.349 , pp. 667-674
    • Julian, D.G.1    Camm, A.J.2    Frangin, G.3
  • 11
    • 0031029373 scopus 로고    scopus 로고
    • Randomised trial of outcome after myocardial infarction in patients with frequent or repetitive ventricular premature depolarisations: CAMIAT
    • for the Canadian Amiodarone Myocardial Infarction Arrhythmia Trial Investigators
    • Cairns JA, Connolly SJ, Roberts R, Gent M, for the Canadian Amiodarone Myocardial Infarction Arrhythmia Trial Investigators. Randomised trial of outcome after myocardial infarction in patients with frequent or repetitive ventricular premature depolarisations: CAMIAT. Lancet 1997;349:675-82.
    • (1997) Lancet , vol.349 , pp. 675-682
    • Cairns, J.A.1    Connolly, S.J.2    Roberts, R.3    Gent, M.4
  • 12
    • 2542549569 scopus 로고
    • Colégio Brasileiro de Experimentação Animal (COBEA). São Paulo: Colégio Brasileiro de Experimentaçã o Animal
    • Colégio Brasileiro de Experimentação Animal (COBEA). Princípios acEticos na Experimentação Animal. São Paulo: Colégio Brasileiro de Experimentaçã o Animal, 1991.
    • (1991) Princípios AcEticos Na Experimentação Animal
  • 13
    • 34447581554 scopus 로고
    • Untersuchungen am uberlebenden sangethierherzen
    • Apud in: Doring HJ, Dehnert H, eds. The isolated perfused warm-blooded heart according to Langendorff. In: Methods in Experimental Physiology and Pharmacology, English edn. Berlin: Biomesstechnik-Verlag, 1988
    • Langendorff O. Untersuchungen am uberlebenden sangethierherzen. Pflugers Arch 1895;61:291-332. Apud in: Doring HJ, Dehnert H, eds. The isolated perfused warm-blooded heart according to Langendorff. In: Methods in Experimental Physiology and Pharmacology, English edn. Berlin: Biomesstechnik-Verlag, 1988.
    • (1895) Pflugers Arch. , vol.61 , pp. 291-332
    • Langendorff, O.1
  • 14
    • 0033849637 scopus 로고    scopus 로고
    • The isolated blood and perfusion fluid perfused heart
    • Sufherland FJ, Hearse DJ. The isolated blood and perfusion fluid perfused heart. Pharmacol Res 2000;41:613-27.
    • (2000) Pharmacol. Res. , vol.41 , pp. 613-627
    • Sufherland, F.J.1    Hearse, D.J.2
  • 15
    • 0019411802 scopus 로고
    • Effect of mechanical work load on the transmural distribution of glucose uptake in the isolated perfused rat heart, studied by regional deoxyglucose trapping
    • Takala TE, Hassinen IE. Effect of mechanical work load on the transmural distribution of glucose uptake in the isolated perfused rat heart, studied by regional deoxyglucose trapping. Circ Res 1981;49:62-9.
    • (1981) Circ. Res. , vol.49 , pp. 62-69
    • Takala, T.E.1    Hassinen, I.E.2
  • 16
    • 0021271784 scopus 로고
    • The isolated perfused rat heart: A model for studying myocardial hypoxia or ischaemia
    • de Leiris J, Harding DP, Pestre S. The isolated perfused rat heart: A model for studying myocardial hypoxia or ischaemia. Basic Res Cardiol 1984;79:313-21.
    • (1984) Basic Res. Cardiol. , vol.79 , pp. 313-321
    • de Leiris, J.1    Harding, D.P.2    Pestre, S.3
  • 17
    • 0001792525 scopus 로고
    • Untersuchungen over die hanstoffbildung in tierkorper. Hope scylersz
    • Apud in: Doring HJ, Dehnert H, eds. The isolated perfused warm-blooded heart according to Langendorff. In: Methods in Experimental Physiology and Pharmacology, English edn. Berlin: Biomesstechnik-Verlag, 1988
    • Krebs HA, Henseleit K. Untersuchungen over die hanstoffbildung in tierkorper. Hope scylersz. Phisiol Chem 1932;210:33-66. Apud in: Doring HJ, Dehnert H, eds. The isolated perfused warm-blooded heart according to Langendorff. In: Methods in Experimental Physiology and Pharmacology, English edn. Berlin: Biomesstechnik-Verlag, 1988.
    • (1932) Phisiol. Chem. , vol.210 , pp. 33-66
    • Krebs, H.A.1    Henseleit, K.2
  • 18
    • 85056017294 scopus 로고    scopus 로고
    • Atenolol and fentanyl effects upon heart rate, myocardial contractility and coronary flow in isolated rat hearts
    • (Abst)
    • Maues HK, Padua-Filho WC, Faraj M, Neves HJ, Gomes ES, Gomes OM. Atenolol and fentanyl effects upon heart rate, myocardial contractility and coronary flow in isolated rat hearts. J Mol Cell Cardiol 2001;33:A75. (Abst)
    • (2001) J. Mol. Cell Cardiol. , vol.33
    • Maues, H.K.1    Padua-Filho, W.C.2    Faraj, M.3    Neves, H.J.4    Gomes, E.S.5    Gomes, O.M.6
  • 19
    • 85056017833 scopus 로고    scopus 로고
    • Effect of diazepam and amiodarone on the myocardium contractility response: Experimental study in isolated rat hearts
    • (Abst)
    • Moraes AAP, Padua-Filho WC, Faraj M, Gomes ES, Neves HJ, Gomes OM. Effect of diazepam and amiodarone on the myocardium contractility response: Experimental study in isolated rat hearts. J Mol Cell Cardiol 2001;33:A78. (Abst)
    • (2001) J. Mol. Cell Cardiol. , vol.33
    • Moraes, A.A.P.1    Padua-Filho, W.C.2    Faraj, M.3    Gomes, E.S.4    Neves, H.J.5    Gomes, O.M.6
  • 20
    • 85056017295 scopus 로고    scopus 로고
    • Amiodarone-fentanyl association effect on the myocardial contractility, heart rate and coronary flow: Study in isolated rat heart
    • (Abst)
    • Carvalho AM, Padua-Filho WC, Faraj M, Gomes OM. Amiodarone-fentanyl association effect on the myocardial contractility, heart rate and coronary flow: Study in isolated rat heart. J Mol Cell Cardiol 2001;33:A18. (Abst)
    • (2001) J. Mol. Cell Cardiol. , vol.33
    • Carvalho, A.M.1    Padua-Filho, W.C.2    Faraj, M.3    Gomes, O.M.4
  • 23
    • 0022704135 scopus 로고
    • Influence of long-term antihypertensive therapy on cardiac function, coronary flow and myocardial oxygen consumption in spontaneously hypertensive rats
    • Friberg P, Nordlander M. Influence of long-term antihypertensive therapy on cardiac function, coronary flow and myocardial oxygen consumption in spontaneously hypertensive rats. J Hypertens 1986;4:165-73.
    • (1986) J. Hypertens. , vol.4 , pp. 165-173
    • Friberg, P.1    Nordlander, M.2
  • 24
    • 0033370273 scopus 로고    scopus 로고
    • Beta-adrenergic signalling and threshold adrenaline concentration for induction of fibrillation in the perfused heart pretreated with antihypertensive drugs
    • Gordeladze JO, Sellevold OFM, Jynge P. Beta-adrenergic signalling and threshold adrenaline concentration for induction of fibrillation in the perfused heart pretreated with antihypertensive drugs. Res Exp Med (Berl) 1999;199:129-40.
    • (1999) Res. Exp. Med. (Berl.) , vol.199 , pp. 129-140
    • Gordeladze, J.O.1    Sellevold, O.F.M.2    Jynge, P.3
  • 25
    • 0023749134 scopus 로고
    • Effects of atenolol and some others beta-adrenoceptor blocking agents on norepinephrine-induced responses in isolated and perfused rat hearts
    • Nakasone J, Kato T, Noguchi K, Nagamine F, Sakanashi M. Effects of atenolol and some others beta-adrenoceptor blocking agents on norepinephrine-induced responses in isolated and perfused rat hearts. Jpn J Pharmacol 1988;47:387-95.
    • (1988) Jpn. J. Pharmacol. , vol.47 , pp. 387-395
    • Nakasone, J.1    Kato, T.2    Noguchi, K.3    Nagamine, F.4    Sakanashi, M.5
  • 26
    • 0026042444 scopus 로고
    • Acute effects of amiodarone on ultrastructure and electrical activity of isolated guinea pig hearts
    • Stark G, Windisch M, Haller EM, et al. Acute effects of amiodarone on ultrastructure and electrical activity of isolated guinea pig hearts. Cardiovasc Res 1991;25:807-14.
    • (1991) Cardiovasc. Res. , vol.25 , pp. 807-814
    • Stark, G.1    Windisch, M.2    Haller, E.M.3
  • 29
    • 0023792968 scopus 로고
    • Amiodarone and beta-adrenergic blockers: An interaction with metoprolol but not with atenolol
    • Leor J, Levartowsky D, Sharon C, Farfel Z. Amiodarone and beta-adrenergic blockers: An interaction with metoprolol but not with atenolol. Am Heart J 1988;116:206-7.
    • (1988) Am. Heart J. , vol.116 , pp. 206-207
    • Leor, J.1    Levartowsky, D.2    Sharon, C.3    Farfel, Z.4
  • 31
    • 0023510153 scopus 로고
    • Metoprolol reduces reperfusion-induced fibrillation in the isolated rat heart: Protection is secondary to bradycardia
    • Tosaki A, Szekeres L, Hearse DJ. Metoprolol reduces reperfusion-induced fibrillation in the isolated rat heart: Protection is secondary to bradycardia. J Cardiovasc Pharmacol 1987;10:489-97.
    • (1987) J. Cardiovasc. Pharmacol. , vol.10 , pp. 489-497
    • Tosaki, A.1    Szekeres, L.2    Hearse, D.J.3
  • 33
    • 0026075331 scopus 로고
    • Preservation of membrane phospolipids by propranolol, pindolol and metoprolol: A novel mechanism of action of beta-blockers
    • Liu XK, Engelman RM, Agrawal HR, Das DK. Preservation of membrane phospolipids by propranolol, pindolol and metoprolol: A novel mechanism of action of beta-blockers. J Mol Cell Cardiol 1991;23:1091-100.
    • (1991) J. Mol. Cell Cardiol. , vol.23 , pp. 1091-1100
    • Liu, X.K.1    Engelman, R.M.2    Agrawal, H.R.3    Das, D.K.4
  • 34
    • 0023228686 scopus 로고
    • Protective effects of amiodarone pretreatment on mitochondrial function and high energy phosphates in ischaemic rat heart
    • Nokin P, Jungbluth L, Mouton J. Protective effects of amiodarone pretreatment on mitochondrial function and high energy phosphates in ischaemic rat heart. J Mol Cell Cardiol 1987;19:603-14.
    • (1987) J. Mol. Cell Cardiol. , vol.19 , pp. 603-614
    • Nokin, P.1    Jungbluth, L.2    Mouton, J.3
  • 35
    • 0028802695 scopus 로고
    • Acute amiodarone terminates ventricular fibrillation by modifying cellular Ca++ homeostasis in isolated perfused rat hearts
    • Kojima S, Wu ST, Wikman-Coffelt J, Parmley WW. Acute amiodarone terminates ventricular fibrillation by modifying cellular Ca++ homeostasis in isolated perfused rat hearts. J Pharmacol Exp Ther 1995;275:254-62.
    • (1995) J. Pharmacol. Exp. Ther. , vol.275 , pp. 254-262
    • Kojima, S.1    Wu, S.T.2    Wikman-Coffelt, J.3    Parmley, W.W.4
  • 36
    • 0026440215 scopus 로고
    • A prospective study of the efficacy and safety of adjuvant metoprolol and xamoterol in combination with amiodarone for resistant ventricular tachycardia associated with impaired left ventricular function
    • Bashir Y, Paul VE, Griffith MJ, et al. A prospective study of the efficacy and safety of adjuvant metoprolol and xamoterol in combination with amiodarone for resistant ventricular tachycardia associated with impaired left ventricular function. Am Heart J 1992;124:1233-40.
    • (1992) Am. Heart J. , vol.124 , pp. 1233-1240
    • Bashir, Y.1    Paul, V.E.2    Griffith, M.J.3
  • 37
    • 0024240244 scopus 로고
    • Efficacy and safety of low doses of beta-blocker agents combined with amiodarone in refractory ventricular tachycardia
    • Tonet J, Frank R, Fontaine G, Grosgogeat Y. Efficacy and safety of low doses of beta-blocker agents combined with amiodarone in refractory ventricular tachycardia. Pacing Clin Electrophysiol 1988;11:1984-9.
    • (1988) Pacing Clin. Electrophysiol. , vol.11 , pp. 1984-1989
    • Tonet, J.1    Frank, R.2    Fontaine, G.3    Grosgogeat, Y.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.