Efficacy and safety of carvedilol in patients with chronic heart failure receiving concomitant amiodarone therapy

Journal of Cardiac Failure

Volumn 4, Issue 4, 1998, Pages 281-288

  Krum, Henry ^a   Shusterman, Neil ^b   MacMahon, Stephen ^c   Sharpe, Norman ^c  

^a MONASH UNIVERSITY   (Australia)

^b GLAXOSMITHKLINE   (United Kingdom)

^c UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Amiodarone; Antiarrhythmic; Carvedilol; Heart failure; Blocker

Indexed keywords

AMIODARONE; ANTIARRHYTHMIC AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CARVEDILOL; PLACEBO;

ADULT; AGED; ARTICLE; ATRIOVENTRICULAR BLOCK; CARDIOVASCULAR DISEASE; CHRONIC DISEASE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG INDUCED DISEASE; DRUG SAFETY; FEMALE; HEART ARRHYTHMIA; HEART FAILURE; HEART LEFT VENTRICLE EJECTION FRACTION; HEMODYNAMIC PARAMETERS; HUMAN; HYPOTENSION; ISCHEMIC HEART DISEASE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME;

EID: 0032408143     PISSN: 10719164     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1071-9164(98)90233-0     Document Type: Article

References (15)

1. Packer M, Bristow MR, Cohn JN, Colucci WS, Fowler MB, Gilbea MD, Shusterman NH, for the US Carvedilol Heart Failure Study Group: The effect of carvedilol on morbidity and mortality in patients with chronic heart failure. N Eng J Med 1996;334:1349-55
2. Krum H, Sackner-Bernstein JD, Goldsmith R, Kukin ML, Schwartz B, Penn J, Medina N, Yushak M, Horn E, Katz SD, Levin HR, Neuberg GW, DeLong G, Packer M: Double-blind, placebo-controlled study of the long-term efficacy of carvedilol in severe chronic heart failure. Circulation 1995;92:1499-06
3. Metra M, Nardi M, Giubbini R, Del Cas L: Effects of short and long-term carvedilol administration on rest and exercise hemodynamic variables, exercise capacity and clinical conditions in patients with idiopathic dilated cardiomyopathy. J Am Coll Cardiol 1994;24:1678-87
4. Olsen SL, Gilbert EM, Renlund DG, Taylor DO, Yanowitz FD, Bristow MR: Carvedilol improves left ventricular function and symptoms in chronic heart failure: a double-blind randomised study. J Am Coll Cardiol 1995;25: 1225-31
5. Australia/New Zealand Heart Failure Research Collaborative Group: Randomised, placebo-controlled trial of carvedilol in patients with congestive heart failure due to ischaemic heart disease. Lancet 1997;349:375-80
6. Mason JW: Amiodarone. N Engl J Med 1987;316:455-566
7. Bigger JT Jr: Why patients with congestive heart failure die: arrhythmias and sudden cardiac death. Circulation 1987;75:28-35
8. Cleland JGF, Dargie HJ, Findlay JN, Wilson JT: Clinical, haemodynamic and anti-arrhythmic effects of long term treatment with amiodarone in patients with heart failure. Br Heart J 1987;57:436-45
9. Australia-New Zealand Heart Failure Research Collaborative Group: Effects of carvedilol, a vasolidator-β-blocker, in patients with congestive heart failure due to ischemic heart disease. Circulation 1995;92:212-8
10. Doval HC, Nul R, Grancelli HO, Perrone SV, Bortman GR, Curiel R, for GESICA. Randomised trial of low-dose amiodarone in severe congestive heart failure. Lancet 1994;334:493-4
11. Singh SN, Fletcher RD, Fisher SG, Singh BN, Lewis HD, Deedwania PC, Massie BM, Colling C, Lazzeri D, for the Survival Trial of Antiarrhythmic Therapy in Congestive Heart Failure: Amiodarone in patients with congestive heart failure and asymptomatic ventricular arrhythmia. N Engl J Med 1995;333:77-82
12. Julian DG, Camm AJ, Frangin G, Janse MJ, Munoz JA, Schwartz PJ, Simon P, for the European Myocardial Infarct Amiodarone Trial Investigators: Randomised trial of effect of amiodarone on mortality in patients with left ventricular dysfunction after recent myocardial infarction: EMIAT. Lancet 1997;349:667-74
13. Carins JA, Connoley SJ, Roberts R, Gent M, for the Canadian Amiodarone Myocardial Infarction Arrhythmia Trial Investigators: Randomised trial of outcome after myocardial infarction in patients with frequent or repetitive ventricular premature depolarisations: CAMIAT. Lancet 1997;349:675-82
14. Doughty RN, Whalley GA, Gamble G, MacMahon S, Sharpe N, on behalf of the Australia-New Zealand Heart Failure Research Collaborative Group: Left ventricular remodelling with carvedilol in patients with congestive heart failure due to ischaemic heart disease. J Am Coll Cardiol 1991;29:1060-6
15. MacDonald PS, Keogh AM, Aboyoun C, Amor R, Lund M: The impact of concurrent amiodarone therapy on the response to carvedilol in heart failure. Circulation 1997; 96:1-578 (abstr 3234, suppl 1)