Practice parameters for colon cancer

Diseases of the Colon and Rectum

Volumn 47, Issue 8, 2004, Pages 1269-1284

  Otchy, Daniel ^a   Hyman, Neil H ^a   Simmang, Clifford ^a   Anthony, Thomas ^a   Buie, W Donald ^a   Cataldo, Peter ^a   Church, James ^a   Cohen, Jeffrey ^a   Dentsman, Frederick ^a   Ellis, C Neal ^a   Kilkenny III, John W ^a   Ko, Clifford ^a   Moore, Richard ^a   Orsay, Charles ^a   Place, Ronald ^a   Rafferty, Janice ^a   Rakinic, Jan ^a   Savoca, Paul ^a   Tjandra, Joe ^a   Whiteford, Mark ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA2A INTERFERON; ANTIBIOTIC AGENT; CAPECITABINE; CARCINOEMBRYONIC ANTIGEN; CEFOTAXIME; FLUOROPYRIMIDINE DERIVATIVE; FLUOROURACIL; FOLINIC ACID; HEPARIN; LEVAMISOLE; LOW MOLECULAR WEIGHT HEPARIN; METRONIDAZOLE; MONOCLONAL ANTIBODY; SIALIDASE;

ANASTOMOSIS; ANTIBIOTIC PROPHYLAXIS; BLEEDING; BLOOD TRANSFUSION; CANCER ADJUVANT THERAPY; CANCER DIAGNOSIS; CANCER IMMUNOTHERAPY; CANCER RADIOTHERAPY; CANCER STAGING; CLINICAL TRIAL; COLON CANCER; COLON HEMORRHAGE; COLON OBSTRUCTION; COLON PERFORATION; COLON RESECTION; COMPUTER ASSISTED TOMOGRAPHY; COST EFFECTIVENESS ANALYSIS; ELECTIVE SURGERY; EVIDENCE BASED MEDICINE; HEALTH CARE QUALITY; HUMAN; INFORMED CONSENT; INTESTINE PREPARATION; LAPAROSCOPIC SURGERY; LIVER METASTASIS; LYMPH NODE METASTASIS; MEDICAL DECISION MAKING; MEDICAL SOCIETY; MEDICAL SPECIALIST; MICROSCOPY; OUTPATIENT CARE; OVARIECTOMY; OVARY METASTASIS; PRACTICE GUIDELINE; PREOPERATIVE EVALUATION; REVIEW; SIDE EFFECT; SURGICAL TECHNIQUE; THORAX RADIOGRAPHY; THROMBOEMBOLISM;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CHEMOTHERAPY, ADJUVANT; COLONIC NEOPLASMS; COMBINED MODALITY THERAPY; DIAGNOSIS, DIFFERENTIAL; HUMANS; NEOPLASM STAGING; PROGNOSIS; QUALITY OF HEALTH CARE; RADIOTHERAPY, ADJUVANT;

EID: 4444380378     PISSN: 00123706     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10350-004-0598-8     Document Type: Review

References (152)

1. Jemal A, Murray T, Samuels A, Ghafoor A, Ward E, Thun MJ. Cancer statistics. CA Cancer J Clin 2003;53:5-26.
2. Beart RW, Steele GD, Merck HR, Chmiel JS, Ocwieja KE, Winchester DP. Management and survival of patients with adenocarcinoma of the colon and rectum: a national survey of the Commission on Cancer. J Am Coll Surg 1995;181:225-36.
3. Fuchs CS, Giovannucci EL, Colditz GA, Hunter DJ, Speizer FE, Willett WC. A prospective study of family history and the risk of colorectal cancer. N Engl J Med 1994;331:l669-74.
4. Simmang CL, Senatore P, Lowry A, et al. Practice parameters for detection of colorectal neoplasms. Dis Colon Rectum 1999;42:1123-9.
5. Wiratkapun S, Kraemer M, Seow-Choen F, Ho Y-H, Eu KW. High preoperative serum carcinoembryonic antigen predicts metastatic recurrence in potentially curative colonic cancer: Results of a five-year study. Dis Colon Rectum 2001;44:231-5.
6. Graham RA, Wang S, Catalano PJ, Haller DG. Postsurgical surveillance of colon cancer: preliminary cost analysis of physician examination, carcino-embryonic antigen testing, chest x-ray, and colonoscopy. Ann Surg 1998;228:59-63.
7. Lavin PT, Day J, Holyoke ED, et al. A statistical evaluation of baseline and follow-up carcinoembryonic antigen in patients with resectable colorectal carcinoma. Cancer 1981;47:823-6.
8. Steele G, Ellenberg S, Ramming K, et al. CEA monitoring among patients in multi-institutional adjuvant therapy protocols. Ann Surg 1982;196:162-9.
9. Harrison LE, Guillem JG, Paty P, Cohen A. Preoperative carcinoembryonic antigen predicts outcomes in node-negative coon cancer patients: a multivariate analysis of 572 patients. J Am Coll Surg 1997;185:55-9.
10. McAndrew MR, Saba A. Efficacy of routine preoperative computed tomography scans in colon cancer. Am Surg 1999;65:205-8.
11. Hundt W, Braunschweig R, Reiser M. Abdominal radiology: evaluation of spiral CT in staging of colon and rectum carcinoma. Eur Radiol 1999;9:78-84.
12. Ward J, Naik KS, Guthrie JA, Wilson D, Robinson PJ. Hepatic lesion detection: comparison of MR imaging after the administration of superparamagnetic iron oxide with dual-phase CT by using alternative-free response receiver operating characteristic analysis. Radiology 1999;210:459-66.
13. Brownson P, Jenkins SA, Nott D, et al. Mechanical bowel preparation before colorectal surgery: results of a prospective, randomized trial. Br J Surg 1992;79:46l-2.
14. Burke P, Mealy K, Gillen P, Joyce W, Traynor O, Hyland J. Requirement for bowel preparation in colorectal surgery. Br J Surg 1994;81:580-1.
15. Santos JC, Batista J, Sirimarco MT, Guimaraes AS, Levy CE. Prospective randomized trial of mechanical bowel preparation in patients undergoing elective colorectal surgery. Br J Surg 1994;81:1673-6.
16. Miettinen RP, Laitinen ST, Makela JT, Paakkonen ME. Bowel preparation with oral polyethylene glycol electrolyte solution vs. no preparation in elective open colorectal surgery: prospective, randomized study. Dis Colon Rectum 2000;43:669-77.
17. Zmora O, Mahajna A, Barak B, et al. Colon and rectal surgery without mechanical bowel preparation: randomized prospective trial. Ann Surg 2003;237:363-7.
18. Platell C, Hall J. What is the role of mechanical bowel preparation in patients undergoing colorectal surgery? Dis Colon Rectum 1998;41:875-82.
19. Solla JA, Rothenberger DA. Preoperative bowel preparation: a survey of colon and rectal surgeons. Dis Colon Rectum 1990;33:154-9.
20. Beck DE, Fazio VW. Current preoperative bowel cleansing methods: results of a survey. Dis Colon Rectum 1990;33:12-5.
21. Nichols RL, Smith JW, Garcia RY, Waterman RS, Holmes JW. Current practices of preoperative bowel preparation among North American colorectal surgeons. Clin Infect Dis 1997;24:609-19.
22. Zmora O, Wexner S, Hajjar L, et al. Trends in preparation for colorectal surgery: survey of the members of the American Society of Colon and Rectal Surgeons. Am Surg 2003;69:150-4.
23. Frazee RC, Roberts J, Symmonds R, Snyder S, Hendricks J, Smith R. Prospective, randomized trial of inpatient vs. outpatient bowel preparation for elective colorectal surgery. Dis Colon Rectum 1992;35:223-6.
24. Lee EC, Roberts PL, Tarante R, Schoetz DJ, Murray JJ, Coller JA. Inpatient vs. outpatient bowel preparation for elective colorectal surgery. Dis Colon Rectum 1996; 39:369-73.
25. Baum ML, Anish DS, Chalmers TC, Sacks HS, Smith J, Fagerstrom RM. A survey of clinical trials of antibiotic prophylaxis in colon surgery: evidence against further use of no-treatment controls. N Engl J Med 1981;305:795-8.
26. Fry DE. Antibiotics in surgery. An overview. Am J Surg 1988;155:11-5.
27. Polk HC, Lopez-Mayor JF. Postoperative wound infection: a prospective study of determinant factors and prevention. Surgery 1969;66:97-103.
28. Stone HH, Hooper CA, Kolb LD, Geheber CE, Dawkins EJ. Antibiotic prophylaxis in gastric, biliary, and colonic surgery. Ann Surg 1976;184:443-50.
29. Stone HH, Haney BB, Kolb LD, Geheber CE, Hooper CA. Prophylactic and preventive antibiotic therapy: timing, duration and economics. Ann Surg 1979;189:691-9.
30. Rowe-Jones DC, Peel AL, Kingston RD, Shaw JF, Teasdale C, Cole DS. Single dose cefotaxime plus metronidazole versus three dose cefuroxime plus metronidazole as prophylaxis against wound infection in colorectal surgery: multicentre prospective randomized study. BMJ 1990;300:18-22.
31. Jones RN, Wojeski WV. Single-dose surgical prophylaxis using ticarcillin/clavulanic acid (Timentin): a prospective, randomized comparison with cefotaxime. Diagn Microbiol Infect Dis 1987;7:219-23.
32. Jagelman DG, Fabian TC, Nichols RL, Stone HH, Wilson SE, Zellner SR. Single-dose cefotetan versus multiple-dose cefoxitin as prophylaxis in colorectal surgery. Am J Surg 1988;155:71-6.
33. Colizza S, De Fasio S, Addari A, Grande R, Cucchiara G. Short-term prophylaxis with cefuroxime in colorectal surgery for cancer. J Surg Oncol 1987;35:266-8.
34. Mittermyer H, Gross C, Brucke P. Single dose Cefixime/metronidazole versus metronidazole alone in elective colorectal surgery. Am Surg 1984;50:418-23.
35. Chung M, Steinmetz OK, Gordon PH. Perioperative blood transfusion and outcome after resection for colorectal carcinoma. Br J Surg 1993;80:427-32.
36. Jensen LS, Kissmeyer-Nielsen P, Wolff B, Qvist N. Randomized comparison of leucocyte-depleted versus buffy-coat poor blood transfusion and complications after colorectal surgery. Lancet 1996;348:841-5.
37. Busch OR, Hop WC, Hoynck MA, Marguet RL, Jeekel J. Blood transfusions and prognosis in colorectal cancer. N Engl J Med 1993;328:1372-6.
38. Tang R, Wang JY, Chien CR, Chen JS, Lin SE, Fan HA. The association between perioperative blood transfusion and survival of patients with colorectal cancer. Cancer 1993;72:341-8.
39. Spahn DR. Perioperative transfusion triggers for red blood cells. Vox Sang 2000;78:163-6.
40. Anonymous. Practice guidelines for blood component therapy. A report by the American Society of Anesthesiologists Task Force on Blood Component Therapy. Anesthesiology 1996;84:732-47.
41. Jensen LS, Andersen AJ, Christiansen PM, et al. Postoperative infection and natural killer cell function following blood transfusion in patients undergoing elective colorectal surgery. Br J Surg 1992;79:513-6.
42. Blumberg N, Heal JM. Effects of transfusion on immune function: cancer recurrence and infection. Arch Pathol Lab Med 1994;79:371-9.
43. Fischer E, Lenhard V, Seifert P, Kluge A, Johannsen R. Blood transfusion induced suppression of cellular immunity in man. Hum Immunol 1980;3:187-94.
44. van Twuyver E, Mooijaart RJ, Berge IJ, et al. Pretransplantation blood transfusion revisited. N Engl J Med 1991;325:1210-3.
45. Houbiers JG, van de Velde CJ, van de Watering IM, et al. Transfusion of red cells is associated with increased incidence of bacterial infection after colorectal surgery; a prospective study. Transfusion (Paris) 1997;37:126-34.
46. Vamvakas EC, Caryen JH, Hibbard PL. Blood transfusion and infection after colorectal cancer surgery. Transfusion (Paris) 1996;36:1000-8.
47. Vignali A, Braga M, Dionigi P, et al. Impact of a programme of autologous blood donation on the incidence of infection in patients with colorectal cancer. Eur J Surg 1995;161:487-92.
48. Houbiers JG, Brand A, van de Watering LM, et al. Randomized controlled trial comparing transfusion of leucocyte-depleted or buffy-coat-depleted blood in surgery for colorectal cancer. Lancet 1994;344:573-8.
49. Voogt PG, van de Velde CJ, Brand A, et al. Perioperative blood transfusion and cancer prognosis. Cancer 1987;59:836-43.
50. Heiss MM, Mempel W, Delanoff C, et al. Blood transfusion-modulated tumor recurrence; first results of a randomized study of autologous versus allogenic blood transfusion in colorectal cancer surgery. J Clin Oncol 1994;12:1859-67.
51. Vanvakas EC. Perioperative blood transfusion and cancer recurrence, meta-analysis for explanation. Transfusion (Paris) 1995;35:760-8.
52. Collins R, Scrimgeour A, Yusuf S, Peto R. Reduction in fatal pulmonary embolism and venous thrombosis by perioperative administration of subcutaneous heparin. Overview of results of randomized trials in general, orthopedic and urologic surgery. N Engl J Med 1988; 318:1162-73.
53. Kakkar VV, Howe CT, Nicolaides AN, Renney JT, Clarke MB. Deep venous thrombosis of the leg: is there a "high risk" group? Am J Surg 1970;120:527-30.
54. Ho Y-H, Seow-Choen F, Leong A, Eu K-W, Nyam D, Teoh M-K. Randomized, controlled trial of low molecular weight heparin vs. no deep vein thrombosis prophylaxis for major colon and rectal surgery in Asian patients. Dis Colon Rectum 1999;42:196-203.
55. Kakkar VV, Djazaeri B, Fokm J, Fletcher M, Sculh MF, Westwick J. Low-molecular-weight heparin and prevention of postoperative deep vein thrombosis. Br J Med 1982;284:375-9.
56. Turpie AG, Levin MN, Hirsh J, et al. A randomized controlled trial of a low-molecula-weight heparin (Enoxaprin) to prevent deep-vein thrombosis in patients undergoing elective hip surgery. N Engl J Med 1986;315:925-9.
57. McLeod RS, Geerts WH, Sniderman KW, et al. Subcutaneous heparin versus low-molecular-weight heparin as thromboprophylaxis in patients undergoing colorectal surgery. Results of the Canadian colorectal DVT Prophylaxis Trial: a randomized, double-blind trial. Ann Surg 2001;233:438-44.
58. Etchells E, McLeod RS, Geerts W, Barton P, Petsky AS. Economic analysis of low-dose heparin vs the low-molecular weight heparin Enoxaparin for prevention of venous thromboembolism after colorectal surgery. Arch Intern Med 1999;159:1221-8.
59. Clagett GP, Reisch JS. Prevention of venous thromboembolism in general surgery patients. Results of meta-analysis. Ann Surg 1988;208:227-40.
60. Dentsman F, Lowry A, Vernava A, et al. Practice parameters for the prevention of venous thromboembolism. Dis Colon Rectum 2000;43:1037-47.
61. R French Association for Surgical ResearchRouffett F, Hay J-M, et al. Curative resection for left colonic carcinoma: hemicolectomy vs. segmental colectomy. A prospective, controlled multicenter trial. Dis Colon Rectum 1994;37:651-9.
62. Malassagne B, Valleur P, Serra J, et al. Relationship of apical lymph node involvement to survival in resected colon carcinoma. Dis Colon Rectum 1993;36:645-53.
63. Newland RC, Chapes PH, Smyth EJ. The prognostic value of substaging colorectal cancer. Cancer 1987;60:852-7.
64. Kawamura YJ, Umetani N, Sunami E, Watanabe T, Masaki T, Muto T. Effect of high ligation on the long-term of patients with operable colon cancer, particularly those with limited nodal involvement. Eur J Surg 2000; 166:803-7.
65. Hayash N, Egami H, Kai M, Kurusu Y, Takano S, Ogawa M. No-touch isolation technique reduces intraoperative shedding of tumor cells into the portal vein during resection of colorectal cancer. Surgery 1999; 125:369-74.
66. Wiggers T, Jeekel J, Arends JW, et al. No-touch isolation technique in colon cancer. A controlled prospective trial. Br J Surg 1988;75:409-15.
67. Welch JP. Multiple colorectal tumors: an appraisal of natural history and therapeutic options. Am J Surg 1981;142:274-80.
68. Whelan RL, Wong WD, Goldberg SM, Rothenberger DA. Synchronous bowel anastomoses. Dis Colon Rectum 1989;32:365-8.
69. Sugerbaker PH, Corlew S. Influence of surgical techniques on survival in patients with colorectal cancer: a review. Dis Colon Rectum 1982;25:545-57.
70. Lopez MS, Monafo WW. Role of extended resection in the initial treatment of locally advanced colorectal carcinoma. Surgery 1993;113:365-72.
71. Gall FP, Tonak J, Altendorf A. Multivisceral resections in colorectal cancer. Dis Colon Rectum 1987;30:337-41.
72. Hunter JA, Ryan JA, Schultz P. En bloc resection of colon cancer adherent to other organs. Am J Surg 1987;154:67-71.
73. Hughes KS, Rossi RL. Colorectal cancer metastatic to the liver: resection. In: Cameron J, ed. Current surgical therapy. 4th ed. St. Louis: Mosby 1992:1-5.
74. Taylor M, Forster J, Langer B, Taylor BR, Greig PD, Mahut C. A study of prognostic factors for hepatic resection for colorectal metastases. Am J Surg 1997;173:467-71.
75. Wanebo HJ, Chu QD, Vezeridis MP, Soderberg C. Patient selection for hepatic resection of colorectal metastases. Arch Surg 1996;131:322-8.
76. Lyass S, Zamir G, Matot I, Goitein D, Eid A, Jurim O. Combined colon and hepatic resection for synchronous colorectal liver metastases. J Surg Oncol 2001;78:17-21.
77. deSañtibanes E, Lasalle F, McCormack L, et al. Simultaneous colorectal and hepatic resections for colorectal cancer: postoperative and long-term outcomes. J Am Coll Surg 2002;195:196-202.
78. Cutait R, Lesser ML, Enker WE. Prophylactic oophorectomy in surgery for large-bowel cancer. Dis Colon Rectum 1983;26:6-11.
79. Young-Fadok TM, Wolff BG, Nivatrongs S, Metzger PP, Ilstrup DM. Prophylactic oophorectomy in colorectal carcinoma: preliminary results of a randomized, prospective trial. Dis Colon Rectum 1998;41:277-85.
80. Morrow M, Enker WE. Late ovarian metastases in carcinoma of the colon and rectum. Arch Surg 1984;119:1385-8.
81. Falk PM, Beart RW, Wexner SD, et al. Laparoscopic colectomy: a critical appraisal. Dis Colon Rectum 1993; 36:28-34.
82. Franklin ME, Rosenthal D, Abrego-Medina D, et al. Prospective evaluation of open vs. laparoscopic colon surgery for adenocarcinoma: five-year results. Dis Colon Rectum 1996;39(Suppl):S35-46.
83. Khalili TM, Fleshner PR, Hiatt JR, et al. Colorectal cancer: comparison of laparoscopic with open approaches. Dis Colon Rectum 1998;41:832-8.
84. Moore JE, Bokey EL, Newland RC, et al. Lymphovascular clearance in laparoscopically assisted right hemicolectomy is similar to open surgery. ANZ J Surg 1999; 66:605-7.
85. Hoffman G, Baker J, Fitchett C, Vansant J. Laparoscopic-assisted colectomy. Initial experience. Ann Surg 1994;219:732-43.
86. Hartley JE, Mehigan BJ, Qureshi AE, Duthie GS, Lee PW, Monson JR. Total mesorectal excision: assessment of the laparoscopic approach. Dis Colon Rectum 2001; 44:315-21.
87. Nduka CC, Monson JR, Menzies-Gow N, Darz A. Abdominal wall metastases following laparoscopy. Br J Surg 1994;81:648-52.
88. Wexner SD, Cohen SM. Port site metastases after laparoscopic colorectal surgery for cure of malignancy. Br J Surg 1995;82:295-8.
89. Allendorf JD, Bessler M, Whelan RL, et al. Better preservation of immune function after laparoscopic-assisted vs. open bowel resection in a murine model. Dis Colon Rectum 1996;39:S67-72.
90. Delgado S, Lacy AM, Filella X, et al. Acute phase response in laparoscopic and open colectomy in colon cancer: randomized study. Dis Colon Rectum 2001;44:638-46.
91. Stocchi L, Nelson H. Laparoscopic colectomy for coon cancer: Trial update. J Surg Oncol 1998;68:255-67.
92. Runkel HS, Hinz U, Lehnert T, Buhr HJ, Herfarth C. Improved outcome after emergency surgery for cancer of the large intestine. Br J Surg 1998;85:1260-5.
93. Smithers BM, Theile DE, Cohen JR, Evans EB, Davis NC. Emergency right hemicolectomy in colon carcinoma: a prospective study. ANZ J Surg 1986;56:749-52.
94. Matheson NA. Management of obstructed and perforated large bowel carcinoma. Bailleires Clin Gastroenterol 1989;3:671-97.
95. Gordon PH. Malignant neoplasms of the colon. In: Gordon PH, Nivatvongs S, eds. Principles and practice of surgery for the colon, rectum and anus. St. Louis: Quality Medical Publishing 1999:648-51.
96. Lopez-Kostner F, Hool GR, Lavery IC. Management and causes of acute large bowel obstruction. Surg Clin North Am 1997;77:1265-90.
97. The SCOTIA Group. Single stage treatment for malignant left-sided colonic obstruction: a prospective randomized clinical trial comparing subtotal colectomy with segmental resection following intraoperative irrigation. Br J Surg 1995;82:1622-7.
98. Kopera T, Kisser M, Schultz F. Emergency surgery for colon cancer in the aged. Arch Surg 1997;132:1032-7.
99. Perrier G, Peillon C, Liberge N, Steinmetz L, Boyet L, Testart J. Cecostomy is a useful surgical procedure: study of 113 colonic obstructions caused by cancer. Dis Colon Rectum 2000;43:50-4.
100. Kronberg O. Acute obstruction from tumor in the left colon without spread. A randomized trial of emergency colostomy versus resection. Int J Colorectal Dis 1995;10:1-5.
101. Dauphine CE, Tan P, Beart RW, Vukasin P, Cohen H, Corman ML. Placement of self-expanding metal stents for acute management of large-bowel obstruction: a collective review. Ann Surg Oncol 2002;9:574-9.
102. Spinelli P, Mancini A. Use of self-expanding metal stents for palliation of rectosigmoid cancer. Gastrointest Endosc 2001;53:203-6.
103. Binkert CA, Ledermann H, Jost R, Saurenmann P, Decurtins M, Zollikofer CL. Acute colonic obstruction: clinical aspects and cost-effectiveness of preoperative and palliative treatment with self-expanding metallic stents' a preliminary report. Radiology 1998;206:199-204.
104. Camunez F, Echenagusia A, Simo G, Turgano F, Vasquez J, Barreiro-Meiro I. Malignant colorectal obstruction treated by means of self-expanding metallic stents: effectiveness before surgery and in palliation. Radiology 2000;216:492-7.
105. Corman ML. Carcinoma of the colon. In: Corman ML, ed. Colon and rectal surgery. Philadelphia: Lippincott-Raven 1998:625-732.
106. Vernava AM, Moore BA, Longo WE, Johnson FE. Lower gastrointestinal bleeding. Dis Colon Rectum 1997;40:846-58.
107. Parkes BM, Obeid FN, Sorensen VJ, Horst HM, Fath JJ. The management of massive lower gastrointestinal bleeding. Am Surg 1993;59:676-8.
108. Farner F, Lichliter W, Kuhn J, Fisher T. Total colectomy versus limited colonic resection for acute lower gastrointestinal bleeding. Am J Surg 1999;178:587-91.
109. Yarbro JW, Page DL, Fielding LP, Partridge EE, Murphy GP. American Joint Committee on Cancer prognostic factors consensus conference. Cancer 1999;86:2436-46.
110. Williams ST, Beart RW. Staging of colorectal cancer. Semin Surg Oncol 1992;8:89-93.
111. International Working Group in Colorectal Cancer (IWGCRC). An international multidisciplinary approach to the management of advanced colorectal cancer. Ann Chir Gynaecol 1998;87:255-64.
112. Jass JR, Love SB, Northover JM. A new prognostic classification of rectal cancer. Lancet 1987;1:1303-6.
113. Fielding LP, Arsenault PA, Chapuis PH, et al. Clinicopathological staging for colorectal cancer: an International Documentation System (IDS) and an International Comprehensive Anatomical Terminology (ICAT). J Gastroenterol Hepatol 1991;6:325-44.
114. Green F, Page D, Flemming I, et al. AJCC cancer staging manual. 6th ed. New York: Springer-Verlag 2002:113-23.
115. Knudsen JB, Nilsson T, Sprechler M, Johnasen A, Christensen N. Venous and nerve invasion as prognostic factors in postoperative survival of patients with resectable cancer of the rectum. Dis Colon Rectum 1983;26:613-7.
116. Venkatesh KS, Weingart DJ, Ramanujum PJ. Comparison of double and single parameters in DNA analysis for staging and as a prognostic indicator in patients with colon and rectal carcinoma. Dis Colon Rectum 1994;37:1142-7.
117. Thibodeau SN, French AJ, Cunningham JM, et al. Microsatellite instability in colorectal cancer: different mutator phenotypes and the principal involvement of hMLH1. Cancer Res 1998;58:1713-8.
118. Justice AC, Covinsky KE, Berlin JA. Assessing the generalizability of prognostic information. Ann Intern Med 1999;130:515-24.
119. Haboubi NY, Clark P, Kaftan SM, Schofield PF. The importance of combining xylene clearance and immunohistochemistry in the accurate staging of colorectal carcinoma. J R Soc Med 1992;85:386-8.
120. Scott KW, Grace RH. Detection of lymph node metastases in colorectal carcinoma before and after fat clearance. Br J Surg 1989;76:1165-7.
121. Cserni G, Vajda K, Tarjan M, Bori R, Svebis M, Baltas B. Nodal staging of colorectal carcinomas from quantitative and qualitative aspects. Can lymphatic mapping help staging? Pathol Oncol Res 1999;5:291-6.
122. Goldstein NS, Sanford W, Coffey M, Layfield LJ. Lymph node recovery from colorectal resection specimens removed for adenocarcinoma: trends over time and a recommendation for a minimum number of lymph nodes to be recovered. Am J Clin Pathol 1996;106:209-16.
123. Hernanz F, Revuelta S, Redondo C, Madrazo C, Castillo J, Gomez-Fleitas M. Colorectal adenocarcinoma: quality of the assessment of lymph node metastases. Dis Colon Rectum 1994;37:373-7.
124. Herrera-Ornelas L, Justiniano J, Castillo N, Petrelli NJ, Stulc JP, Mittelman A. Metastases in small lymph nodes from colon cancer. Arch Surg 1987;122:1253-6.
125. Tang R, Wang JY, Chen JS, et al. Survival impact of lymph node metastasis in TNM Stage III carcinoma of the colon and rectum. J Am Coll Surg 1995;180:705-12.
126. Bilchik AJ, Saha S, Wiese D, et al. Molecular staging of early colon cancer on the basis of sentinel node analysis: a multicenter phase II trial. J Clin Oncol 2001;19:1128-36.
127. Liefers GJ, Cleton-Jansen AM, Van De Velde CJ, et al. Micrometastases and survival in stage II colorectal cancer. N Engl J Med 1998;339:223-8.
128. Thebo JS, Senagore AJ, Reinhold DS, Stapleton SR. Molecular staging of colorectal cancer: K-ras mutation analysis of lymph nodes upstages Dukes B patients. Dis Colon Rectum 2000;43:155-62.
129. Greenson JK, Isenhart CE, Rice R, Mojzisik C, Houchens D, Martin EW. Identification of occult micrometastases in pericolic lymph nodes of Dukes' B colorectal cancer patients using monoclonal antibodies against cytokeratin and CC49. Cancer 1994;73:563-9.
130. Jeffers MD, O'Dowd FM, Mulcahy H, Stagg M, O'Donoghue DP, Toner M. The prognostic significance of immunohistochemically detected lymph node micrometastases in colorectal carcinoma. J Pathol 1994;172:183-7.
131. O'Connell MJ, Laurie JA, Kahn M, et al. Prospectively randomized trial of postoperative adjuvant chemotherapy in patients with high-risk colon cancer. J Clin Oncol 1998;16:295-300.
132. QUASAR Collaborative Group. Comparison of fluorouracil with additional levamisole, higher dose folinic acid, or both, as adjuvant chemotherapy for colorectal cancer: a randomized trial. Lancet 2000;355:1588-96.
133. Fountzilas G, Zisiadis A, Dafni U, et al. Fluorouracil and leucovorin with or without interferon alfa-2a as adjuvant treatment, in patients with high-risk colon cancer: a randomized phase III study conducted by the Hellenic Cooperative Oncology Group. Oncology 2000;58:227-36.
134. Wolmark N, Bryant J, Smith R, et al. Adjuvant 5-fluorouracil and leucovorin with or without interferon alfa-2a in colon carcinoma: NSABP protocol C-05. J Natl Cancer Inst 1998;90:1810-6.
135. Wolmark N, Colangelo L, Wieand S. NSABP trials in colon cancer. Semin Oncol 2001;28:9-13.
136. Bleiberg H. Adjuvant therapy in high-risk colon cancer. Semin Oncol 2000;27 (Suppl):48-59.
137. Marsoni S. Efficacy of adjuvant fluorouracil and leucovorin in stage B2 and C colon cancer. International Multicenter Pooled Analysis of Colon Cancer Trials Investigators. Semin Oncol 2001;28:14-9.
138. Smith RE, Lembersky BC, Wienad HS, Colangelo L, Mamounas EP. UFT/leucovorin vs 5-FU/leucovorin in colon cancer. Oncology 2000;14:24-7.
139. Hoover HC, Brankhorst JS, Peters LC, et al. Adjuvant active specific immunotherapy for human colorectal cancer: 6.5-year median follow-up of a phase III prospectively randomized trial. J Clin Oncol 1993;11: 390-9.
140. Harris J, Ryan L, Adams G, et al. Survival and relapse in adjuvant autologous tumor vaccine therapy for Dukes B and C colon cancer' EST 5283. Proc Am Soc Clin Oncol 1994;13:294.
141. Vermorken JB, Claessen AM, van Tinteren H, et al. Active specific immunotherapy for stage II and stage III human colon cancer: a randomized trial. Lancet 1999;353:345-50.
142. Gray BN, Walker C, Andrewartha L, Freeman S, Bennett RC. Controlled clinical trial of adjuvant immunotherapy with BCG and neuraminidase-treated autologous tumor cells in large bowel cancer. J Surg Oncol 1989;40:34-7.
143. Riethmuller G, Holz E, Schlimok G, et al. Monoclonal antibody therapy for resected Duke's C colorectal cancer: seven-year outcome of a multicenter randomized trial. J Clin Oncol 1998;16:1788-94.
144. Rougier P, Sahmoud T, Nitti D, et al. Adjuvant portal-vein infusion of fluorouracil and heparin in colorectal cancer: a randomized trial. Lancet 1998;351:1677-81.
145. Laffer U, Maubach R, Metzger U, et al. Randomized trial of adjuvant perioperative chemotherapy in radically resected colorectal cancer (SAKK 40/87). Proc Am Soc Clin Oncol 1998;17:256A.
146. James RD. on behalf of the AXIS collaborators: Intraportal 5FU (PVI) and perioperative radiotherapy (RT) in the adjuvant treatment of colorectal cancer (CRCa)-3681 patients randomized in the UK Coordinating Committee on Cancer Research (UKCCCR) AIXS Trial. Proc Am Soc Clin Oncol 1999;18:264A.
147. Labianca R, Boffi L, Marsoni S, et al. A randomized trial of Intraportal (IP) versus systemic (SY) versus IP + SY adjuvant chemotherapy in patients with resected Dukes B-C colon carcinoma (CC). Proc Am Soc Clin Oncol 1999;18:264A.
148. Vaillant JC, Nordlinger B, Deuffic S, et al. Adjuvant intraperitoneal 5-fluorouracil in high-risk colon cancer: a multicenter phase III trial. Ann Surg 2000;231: 449-56.
149. Scheithauer W, Kornek GV, Marczell A, et al. Combined intravenous and intraperitoneal chemotherapy with fluorouracil + leucovorin vs fluorouracil + levamisole for adjuvant therapy of resected colon carcinoma. Br J Cancer 1998;77:1349-54.
150. Merrick HW, Turner SS, Dobelbower RR, Bennett JM, Haller D. Large-field external beam irradiation as a surgical adjuvant for node-positive colon carcinoma: an Eastern Cooperative Oncology Group Pilot Study (PA285). Am J Clin Oncol 2000;23:337-40.
151. Willett CG, Goldberg S, Shellito PC, et al. Does postoperative irradiation play a role in the adjuvant therapy of stage T4 colon cancer? Cancer J Sci Am 1999;5:242-7.
152. Palermo JA, Richards F, Lohman KK, et al. Phase II trial of adjuvant radiation and intraperitoneal 5-fluorouracil for locally advanced colon cancer: results with 10-year follow-up. Int J Radiat Oncol Biol Phys 2000;47:725-33.