Randomized, controlled trial of low molecular weight heparin vs. no deep vein thrombosis prophylaxis for major colon and rectal surgery in Asian patients

Diseases of the Colon and Rectum

Volumn 42, Issue 2, 1999, Pages 196-202

  Ho, Yik Hong ^a   Seow Choen, Francis ^a   Leong, Adrian ^a   Eu, Kong Weng ^a   Nyam, Denis ^a   Teoh, Meng Keng ^a  

^a SINGAPORE GENERAL HOSPITAL   (Singapore)

Author keywords

Colon; Rectum; Surgery; Venous thrombosis

Indexed keywords

ENOXAPARIN; LOW MOLECULAR WEIGHT HEPARIN;

ARTICLE; ASIAN; BLEEDING; CLINICAL TRIAL; COLORECTAL SURGERY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEEP VEIN THROMBOSIS; DOPPLER FLOWMETRY; DRUG EFFICACY; HUMAN; INCIDENCE; MAJOR CLINICAL STUDY; PROPHYLAXIS; RANDOMIZED CONTROLLED TRIAL; SUBDURAL HEMATOMA; TREATMENT INDICATION; TREATMENT OUTCOME;

EID: 0032973082     PISSN: 00123706     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02237127     Document Type: Article

References (34)

1. Mann CV, Russel RC, eds. Bailey and Love's short practice of surgery. 21st ed. London: HK Lewis & Co., 1991:241.
2. Tsakok FH. Thromboembolism diseases in women. Ann Acad Med Singapore 1974;3:399-403.
3. Hwang WS. The rarity of pulmonary thromboembolism in Asians. Singapore Med J 1968;9:276-9.
4. Tinckler LF. Absence of pulmonary embolism in Asians. Br Med J 1964;i:502.
5. Kum CK, Sim EK, Ngoi SS. Deep vein thrombosis complicating colorectal surgery in the Chinese in Singapore. Ann Acad Med Singapore 1993;22:895-7.
6. Ho YH. Deep venous thrombosis in colorectal surgery. Proceedings of the Singapore General Hospital, Singapore: Armour Publishing 1996;5:38-45.
7. Knight B. Fatal pulmonary embolism: factors of forensic interest in 400 cases. Med Sci Law 1966;6:103-36.
8. Knight B, Zaini MR. Pulmonary embolism and venous thrombosis: a pattern of incidence and predisposing factors over 70 years. Am J Forensic Med Pathol 1980; 1:227-32.
9. Hartvist F. Autopsy findings in cases with clinically uncertain cancer diagnosis. J Pathol 1979;129:111-9.
10. Karwinski B, Svendsen E. Comparison of clinical and post-mortem diagnosis of pulmonary embolism. J Clin Pathol 1989;42:135-9.
11. Svendsen E, Karwinski B. Prevalence of pulmonary embolism at necropsy in patients with cancer. J Clin Pathol 1989;42:805-9.
12. Freeman DG. Frequency of pulmonary thromboembolism in man. N Engl J Med 1965;24:1278.
13. Havig O. Deep vein thrombosis and pulmonary embolism. An autopsy study with multiple regression and analysis of possible risk factors. Acta Chir Scand 1977; 478(Suppl):4-76.
14. Morrell MT, Dunhill MS. The post-mortem incidence of pulmonary embolism in a hospital population. Br J Surg 1968;55:347-9.
15. Nurmohamed MT, Haas S, Iriarte JA, et al. A comparative trial of a low molecular weight heparin (enoxaparin) versus standard heparin for the prophylaxis of post-operative deep vein thrombosis in general surgery. Am J Surg 1995;169:567-71.
16. Kakkar W, Cohen AT, Edmonson RA, et al. Low molecular weight versus standard heparin for prevention of venous thromboembolism after major abdominal surgery. Lancet 1993;341:259-65.
17. Kakkar VV. Efficacy and safety of Clivarin and other LMWHs in general surgery: a meta-analysis. Blood Coagul Fibrinolysis 1993;4(Suppl 1):S23-7.
18. Leizorovicz A, Haugh MC, Chapuis FR, Samama MM, Boissel JP. Low molecular weight heparin in prevention of perioperative thrombosis. Br Med J 1992;304:913-20.
19. Gazzaniga GM, Angelini G, Pastorino G, Santoro E, Lucchini M, Dal-Pra ML. Enoxaparin in the prevention of deep venous thrombosis after major surgery: multi-centre study. Int Surg 1993;78:271-5.
20. Thromboembolic Risk Factors (THRIFT) Consensus Group. Risk of prophylaxis for venous thromboembolism in hospital patients. Br Med J 1992;305:567-74.
21. Croman JJ, Dorfman GS, Scola FH, Schepps B, Alexander J. Deep vein thrombosis: US assessment using vein compression. Radiology 1987;162:191-4.
22. Salzman EW, Hirsch J. Prevention of venous thrombo-embolism. In: Colman RW, Hirsch J, Marder V, Salzman EW, eds. Hemostasis and thrombosis: basic principles and clinical practice. New York: Lippincott, 1982:986.
23. Samama M, Bernard P, Bonnardot JP, Sophie C-T, Lanson Y, Tissot E. Low molecular weight heparin compared with unfractionated heparin in prevention of postoperative thrombosis. Br J Surg 1988;75:128-31.
24. Warkentin TE, Levine MN, Hirsh J, et al. Heparin-induced thrombocytopaenia in patients treated with low-molecular-weight heparin or unfractionated heparin. N Engl J Med 1995;332:1330-5.
25. Anderson FA Jr, Wheeler HB, Goldberg RJ, Hosmer DW, Forcier A, Patwardhan NA. Physician practices in the prevention of venous thromboembolism. Ann Intern Med 1991;115:591-5.
26. Gordon PH, Nivatvongs S. Principles and practice of surgery for the colon, rectum and anus. St. Louis: Quality Medical Publishing, 1992.
27. Koppenhagen K, Adolf J, Matthes M, et al. Low molecular weight heparin and prevention of postoperative thrombosis in abdominal surgery. Thromb Haemost 1992;67:627-30.
28. Garcia D, Martuzzi F, Santelmo N, et al. Post-surgical deep vein thrombosis prevention: evaluation of the risk/benefit ratio of fractionated and unfractionated heparin. Curr Med Res Opin 1992;12:572-83.
29. Haas S, Flosbach CW. Prevention of post-operative thromboembolism in general surgery with enoxaparin: preliminary findings. Acta Chir Scand Suppl 1990;556: 96-102.
30. Kavoussi LR, Sosa E, Chandhoke P, et al. Complications of laparoscopic pelvic lymph node dissection. J Urol 1993;149:322-5.
31. Ortiz H, De Miguel M, Armendariz P, Rodriguez J, Chocarro C. Coloanal anastomosis: are functional results better with a pouch? Dis Colon Rectum 1995;38:375-7.
32. Moran BJ, Blenkinsop J, Finnis D. Local recurrence after anterior resection for rectal cancer using a double stapling technique. Br J Surg 1992;79:836-8.
33. Lowe GD, Greer IA, Coole TG, et al. Risk of and prophylaxis for venous thrombosis in hospital patients. Br Med J 1992;305:567-74.
34. Ellis CN, Boggs HW, Slagle GW, Cole PA, Coyle DJ, Blakemore WS. Protein C activity, stage of disease, and vascular thrombosis in colon carcinoma. Am J Surg 1992;163:78-81.