A new strategy for the synthesis of oligodeoxynucleotides directed towards perfect O-selective internucleotidic bond formation without base protection

Tetrahedron Letters

Volumn 45, Issue 2, 2004, Pages 363-366

  Ohkubo, Akihiro ^a,c   Seio, Kohji ^b,c   Sekine, Mitsuo ^a,c  

^a TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^b Frontier Collaborative Research Center   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Activator; Chemical synthesis of DNA; HOBt; O Selective phosphorylation; Phosphoramidite approach without base protection

Indexed keywords

OLIGODEOXYNUCLEOTIDE DERIVATIVE;

ARTICLE; CHEMICAL BOND; CHEMICAL MODIFICATION; N PHOSPHITYLATION; NUCLEOTIDE METABOLISM; SYNTHESIS;

EID: 0346366644     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2003.10.156     Document Type: Article

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