Atherosclerosis

Autoimmunity

Volumn 37, Issue 4, 2004, Pages 351-355

  Nilsson, Jan ^a   Fredrikson, Gunilla Nordin ^a,b  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b MALMÖ UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN B100; HEAT SHOCK PROTEIN 60; HEAT SHOCK PROTEIN 65; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; MALONALDEHYDE; OXIDIZED LOW DENSITY LIPOPROTEIN; PEPTIDE ANTIBODY; PHOSPHOLIPID ANTIBODY; PROTEIN ANTIBODY;

ANGIOCARDIOGRAPHY; ANTIBODY TITER; ARTICLE; ATHEROSCLEROTIC PLAQUE; CARDIOVASCULAR RISK; CORONARY ARTERY ATHEROSCLEROSIS; DIAGNOSTIC VALUE; DISEASE MARKER; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; HEART DEATH; HEART INFARCTION; HUMAN; LIPID OXIDATION; NONHUMAN; PREDICTION; RISK ASSESSMENT; SUDDEN DEATH; TRANSLUMINAL CORONARY ANGIOPLASTY;

ANTIGENS; ARTERIOSCLEROSIS; AUTOANTIBODIES; BIOLOGICAL MARKERS; CHOLESTEROL, LDL; HEAT-SHOCK PROTEINS; HUMANS; OXIDATION-REDUCTION; PEPTIDE FRAGMENTS; PHOSPHOLIPIDS; PROGNOSIS;

EID: 4444344600     PISSN: 08916934     EISSN: None     Source Type: Journal    
DOI: 10.1080/08916930410001705402     Document Type: Article

References (50)

1. Tuzcu, E.M., Kapadia, S.R., Tutar, E., Ziada, K.M., Hobbs, R.E., McCarthy, P.M., Young, J.B. and Nissen, S.E. (2001) "High prevalence of coronary atherosclerosis in asymptomatic teenagers and young adults: evidence from intravascular ultrasound", Circulation 103, 2705-2710.
2. Ross, R. (1999) "Atherosclerosis - an inflammatory disease", N. Engl. J. Med. 340, 115-126.
3. Glass, C.K. and Witztum, J.L. (2001) "Atherosclerosis: the road ahead", Cell 104, 503-516.
4. Berliner, J., Navab, M., Fogelman, A., Frank, J., Demer, L., Edwards, P., Watson, A. and Lusis, A.J. (1995) "Atherosclerosis: basic mechanisms. Oxidation, inflammation and genetics", J. Clin. Investig. 91, 2488-2496.
5. Libby, P (2002) "Inflammation in atherosclerosis", Nature 420, 868-874.
6. Palinski, W. and Witztum, J.L. (2000) "Immune responses to oxidative neoepitopes on LDL and phospholipids modulate the development of atherosclerosis", J. Intern. Med. 247, 371-380.
7. Binder, C.J., Chang, M.K., Shaw, P.X., Miller, Y.I., Hartvigsen, K., Dewan, A. and Witztum, J.L. (2002) "Innate and acquired immunity in atherogenesis", Nat. Med. 8, 1218-1226.
8. Hansson, G.K., Libby, P., Schonbeck, U. and Yan, Z.Q. (2002) "Innate and adaptive immunity in the pathogenesis of atherosclerosis", Circ. Res. 91, 281-291.
9. Stemme, S., Faber, B., Holm, J., Wiklund, O., Witztum, J.L. and Hansson, G.K. (1995) "T lymphocytes from human atherosclerotic plaques recognize oxidized low density lipoprotein", Proc. Natl. Acad. Sci. USA 92, 3893-3897.
10. Palinski, W., Miller, E. and Witztum, J.L. (1995) "Immunization of low density lipoprotein (LDL) receptor-deficient rabbits with homologous malondialdehyde-modified LDL reduces atherogenesis", Proc. Natl. Acad. Sci. USA 92, 821-825.
11. Ameli, S., Hultgårdh-Nilsson, A., Regnström, J., Calara, F., Yano, J., Cercek B., Shah, P.K. and Nilsson, J. (1996) "Effect of immunization with homologous LDL on early atherosclerosis in hypercholesterolemic rabbits", Arterioscler. Thromb. Vasc. Biol. 16, 1074-1079.
12. Nilsson, J., Calara, F., Regnström, J., Hultgårdh-Nilsson, A., Ameli, S., Cercek, B. and Shah, P. (1997) "Immunization with homologous oxidized low density lipoprotein reduces neointimal formation after balloon in hypercholesterolemic rabbits", J. Am. Coll. Cardiol. 30, 1886-1891.
13. Freigang, S., Horkko, S., Miller, E., Witztum, J.L. and Palinski, W. (1998) "Immunization of LDL receptor-deficient mice with homologous malondialdehyde-modified and native LDL reduces progression of atherosclerosis by mechanisms other than induction of high titers of antibodies to oxidative neoepitopes", Arterioscler. Thromb. Vasc. Biol. 18, 1972-1982.
14. George, J., Afek, A., Gilburd, B., Levkovitz, H., Shaish, A., Goldberg, I., Kopolovic, Y., Wick, G., Shoenfeld, Y. and Harats, D. (1998) "Hyperimmunization of apo-E-deficient mice with homologous malondialdehyde low-density lipoprotein suppresses early atherogenesis", Atherosclerosis 138, 147-152.
15. Zhou, X., Caligiuri, G., Hamsten, A., Lefvert, A.K. and Hansson, G.K. (2001) "LDL immunization induces T-cell-dependent antibody formation and protection against atherosclerosis", Arterioscler. Thromb. Vasc. Biol. 21, 108-114.
16. Lehtimaki, T., Lehtinen, S., Solakivi, T., Nikkila, M., Jaakkola, O., Jokela, H., Yla-Herttuala, S., Luoma, J.S., Koivula, T. and Nikkari, T. (1999) "Autoantibodies against oxidized low density lipoprotein in patients with angiographically verified coronary artery disease", Arterioscler. Thromb. Vasc. Biol. 19, 23-27.
17. Inoue, T., Uchida, T., Kamishirado, H., Takayanagi, K., Hayashi, T. and Morooka, S. (2001) "Clinical significance of antibody against oxidized low density lipoprotein in patients with atherosclerotic coronary artery disease", J. Am. Coll. Cardiol. 37, 775-779.
18. Tornvall, P., Waeg, G., Nilsson, J., Hamsten, A. and Regnstrom, J. (2003) "Autoantibodies against modified low-density lipoproteins in coronary artery disease", Atherosclerosis 167, 347-353.
19. Boullier, A., Hamon, M., Walters-Laporte, E., Martin-Nizart, F., Mackereel, R., Fruchart, J.C., Bertrand, M. and Duriez, P. (1995) "Detection of autoantibodies against oxidized low-density lipoproteins and of IgG-bound low density lipoproteins in patients with coronary artery disease", Clin. Chim. Acta 238, 1-10.
20. van de Vijver, L.P., Steyger, R., van Poppel, G., Boer, J.M., Kruijssen, D.A., Seidell, J.C. and Princen, H.M. (1996) " Autoantibodies against MDA-LDL in subjects with severe and minor atherosclerosis and healthy population controls", Atherosclerosis 122, 245-253.
21. McDowell, A., Young, I.S. and Wisdom, G.B. (2002) "Autoantibodies to malondialdehyde-modified low-density lipoprotein in patients with angiographically confirmed coronary artery disease" , J. Pharm. Pharmacol. 54, 1651-1657.
22. Rossi, G.P., Cesari, M., De Toni, R., Zanchetta, M., Maiolino, G., Pedon, L., Ganzaroli, C., Maiolino, P. and Pessina, A.C. (2003) "Antibodies to oxidized low-density lipoproteins and angiographically assessed coronary artery disease in white patients" , Circulation 108, 2467-2472.
23. Karvonen, J., Paivansalo, M., Kesaniemi, Y.A. and Horkko, S. (2003) "Immunoglobulin M type of autoantibodies to oxidized low-density lipoprotein has an inverse relation to carotid artery atherosclerosis", Circulation 108, 2107-2112.
24. Fukumoto, M., Shoji, T., Emoto, M., Kawagishi, T., Okuno, Y. and Nishizawa, Y. (2000) "Antibodies against oxidized LDL and carotid artery intima-media thickness in a healthy population", Arterioscler. Thromb. Vasc. Biol. 20, 703-707.
25. Hulthe, J., Bokemark, L. and Fagerberg, B. (2001) "Antibodies to oxidized LDL in relation to intima-media thickness in carotid and femoral arteries in 58-year-old subjectively clinically healthy men", Arterioscler. Thromb Vasc. Biol. 21, 101-107.
26. Palinski, W., Horkko, S., Miller, E., Steinbrecher, U.P., Powell, H.C., Curtiss, L.K. and Witztum, J.L. (1996) "Cloning of monoclonal autoantibodies to epitopes of oxidized lipoproteins from apolipoprotein E-deficient mice. Demonstration of epitopes of oxidized low density lipoprotein in human plasma", J. Clin. Investig. 98, 800-814.
27. Horkko, S., Bird, D.A., Miller, E., Itabe, H., Leitinger, N., Subbanagounder, G., Berliner, J.A., Friedman, P., Dennis, E.A., Curtiss, L.K., Palinski, W. and Witztum, J.L. (1999) "Monoclonal autoantibodies specific for oxidized phospholipids or oxidized phospholipid-protein adducts inhibit macrophage uptake of oxidized low-density lipoproteins", J. Clin. Investig. 103, 117-128.
28. Friedman, R, Horkko, S., Steinberg, D., Witztum, J.L. and Dennis, E.A. (2002) "Correlation of antiphospholipid antibody recognition with the structure of synthetic oxidized phospholipids. Importance of Schiff base formation and aldol concentration", J. Biol. Chem. 277, 7010-7020.
29. Chang, M.K., Bergmark, C., Laurila, A., Horkko, S., Han, K.H., Friedman, P., Dennis, E.A. and Witztum, J.L. (1999) " Monoclonal antibodies against oxidized low-density lipoprotein bind to apoptotic cells and inhibit their phagocytosis by elicited macrophages: evidence that oxidation-specific epitopes mediate macrophage recognition", Proc. Natl. Acad. Sci. USA 96, 6353-6358.
30. Shaw, P.X., Horkko, S., Chang, M.K., Curtiss, L.K., Palinski, W., Silverman, G.J. and Witztum, J.L. (2000) "Natural antibodies with the T15 idiotype may act in atherosclerosis, apoptotic clearance, and protective immunity", J. Clin. Investig. 105, 1731-1740.
31. Briles, D.E., Forman, C., Hudak, S. and Claflin, J.L. (1982) "Antiphosphorylcholine antibodies of the T15 idiotype are optimally protective against Streptococcus pneumoniae", J. Exp. Med. 156, 1177-1185.
32. Horkko, S., Olee, T., Mo, L., Branch, D.W., Woods, V.L. Jr, Palinski, W., Chen, P.P. and Witztum, J.L. (2001) "Anticardiolipin antibodies from patients with the antiphospholipid antibody syndrome recognize epitopes in both beta(2)-glycoprotein 1 and oxidized low-density lipoprotein", Circulation 103, 941-946.
33. Love, P.E. and Santoro, S.A. (1990) "Antiphospholipid antibodies: anticardiolipin and the lupus anticoagulant in systemic lupus erythematosus (SLE) and in non-SLE disorders. Prevalence and clinical significance", Ann. Intern. Med. 112, 682-698.
34. McNeil, H.P., Simpson, R.J., Chesterman, C.N. and Krilis, S.A. (1990) "Anti-phospholipid antibodies are directed against a complex antigen that includes a lipid-binding inhibitor of coagulation: beta 2-glycoprotein I (apolipoprotein H)", Proc. Natl. Acad. Sci. USA. 87, 4120-4124.
35. Bevers, E.M., Galli, M., Barbui, T., Comfurius, P. and Zwaal, R.F. (1991) "Lupus anticoagulant IgG's (LA) are not directed to phospholipids only, but to a complex of lipid-bound human prothrombin", Thromb. Haemost. 66, 629-632.
36. Fredrikson, G.N., Hedblad, B., Berglund, G., Alm, R., Ares, M., Cercek, B., Chyu, K.Y., Shah, P.K. and Nilsson, J. (2003) "Identification of immune responses against aldehyde-modified peptide sequences in ApoB associated with cardiovascular disease", Arterioscler. Thromb. Vasc. Biol. 23, 872-878.
37. Fredrikson, G.N., Soderberg, I., Lindholm, M., Dimayuga, P., Chyu, K.Y., Shah, P.K. and Nilsson, J. (2003) "Inhibition of Atherosclerosis in ApoE-Null mice by immunization with ApoB-100 peptide sequences", Arterioscler. Thromb. Vasc. Biol. 23, 879-884.
38. Wick, G. and Xu, Q. (1999) "Atherosclerosis - an autoimmune disease", Exp. Gerontol. 34, 559-566.
39. Perschinka, H., Mayr, M., Millonig, G., Mayerl, C., Van Der Zee, R., Morrison, S.G., Morrison, R.P., Xu, Q. and Wick, G. (2003) "Cross-reactive B-cell epitopes of microbial and human heat shock protein 60/65 in atherosclerosis", Arterioscler. Thromb. Vasc. Biol. 23, 1060-1065.
40. Afek, A., George, J., Gilburd, B., Rauova, L., Goldberg, I., Kopolovic, J., Harats, D. and Shoenfeld, Y. (2000) "Immunization of low-density lipoprotein receptor deficient (LDL-RD) mice with heat shock protein 65 (HSP-65) promotes early atherosclerosis", J. Autoimmun. 14, 115-121.
41. Xu, Q., Dietrich, H., Steiner, H.J., Gown, A.M., Schoel, B., Mikuz, G., Kaufmann, S.H. and Wick, G. (1992) "Induction of arteriosclerosis in normocholesterolemic rabbits by immunization with heat shock protein 65", Arterioscler. Thromb. 12, 789-799.
42. Lamb, D.J. and Ferns, G.A. (2002) "The magnitude of the immune response to heat shock protein-65 following BCG immunisation is associated with the extent of experimental atherosclerosis", Atherosclerosis 165, 231-240.
43. Birnie, D.H., Holme, E.R., McKay, I.C., Hood, S., McColl, K.E. and Hillis, W.S. (1998) "Association between antibodies to heat shock protein 65 and coronary atherosclerosis. Possible mechanism of action of Helicobacter pylori and other bacterial infections in increasing cardiovascular risk", Eur. Heart J. 19, 387-394.
44. Xu, Q., Willeit, J., Marosi, M., Kleindienst, R., Oberhollenzer, F., Kiechl, S., Stulnig, T., Luef, G. and Wick, G. (1993) "Association of serum antibodies to heat-shock protein 65 with carotid atherosclerosis", Lancet 341, 255-259.
45. Salonen, J.T., Yla-Herttuala, S., Yamamoto, R., Butler, S., Korpela, H., Salonen, R., Nyyssonen, K., Palinski, W. and Witztum, J.L. (1992) "Autoantibody against oxidised LDL and progression of carotid atherosclerosis", Lancet 339, 883-887.
46. Puurunen, M., Manttari, M., Manninen, V., Tenkanen, L., Alfthan, G., Ehnholm, C., Vaarala, O., Aho, K. and Palosuo, T. (1994) "Antibody against oxidized low-density lipoprotein predicting myocardial infarction", Arch. Intern. Med. 154, 2605-2609.
47. Vaarala, O., Manttari, M., Manninen, V., Tenkanen, L., Puurunen, M., Aho, K. and Palosuo, T. (1995) "Anti-cardiolipin antibodies and risk of myocardial infarction in a prospective cohort of middle-aged men", Circulation 91, 23-27.
48. Wu, R., Nityanand, S., Berglund, L., Lithell, H., Holm, G. and Lefvert, A.K. (1997) "Antibodies against cardiolipin and oxidatively modified LDL in 50-year-old men predict myocardial infarction", Arterioscler. Thromb. Vasc. Biol. 17, 3159-3163.
49. Inoue, T., Uchida, T., Kamishirado, H., Takayanagi, K. and Morooka, S. (2001) "Antibody against oxidized low density lipoprotein may predict progression or regression of atherosclerotic coronary artery disease", J. Am. Coll. Cardiol. 37, 1871-1876.
50. Xu, Q., Kiechl, S., Mayr, M., Metzler, B., Egger, G., Oberhollenzer, R, Willeit, J. and Wick, G. (1999) "Association of serum antibodies to heat-shock protein 65 with carotid atherosclerosis: clinical significance determined in a follow-up study", Circulation 100, 1169-1174.