-
1
-
-
0033154824
-
Angiogenesis research: From laboratory to clinic
-
Folkman J: Angiogenesis research: from laboratory to clinic. Forum (Genova) 9: 3 Suppl 3: 59-62, 1999.
-
(1999)
Forum (Genova)
, vol.9
, Issue.SUPPL. 3
, pp. 59-62
-
-
Folkman, J.1
-
2
-
-
0030191756
-
Molecular framework for angiogenesis
-
Senger DR: Molecular framework for angiogenesis. Am J Pathol 149: 1-8, 1996.
-
(1996)
Am J Pathol
, vol.149
, pp. 1-8
-
-
Senger, D.R.1
-
3
-
-
0028090642
-
Vascular endothelial growth factor and glioma angiogenesis: Coordinate induction of VEGF receptors, distribution of VEGF protein and possible in vivo mechanisms
-
Plate KH, Breier G, Weich HA, Mennel HD and Risau W: Vascular endothelial growth factor and glioma angiogenesis: coordinate induction of VEGF receptors, distribution of VEGF protein and possible in vivo mechanisms. Int J Cancer 15: 520-9, 1994.
-
(1994)
Int J Cancer
, vol.15
, pp. 520-529
-
-
Plate, K.H.1
Breier, G.2
Weich, H.A.3
Mennel, H.D.4
Risau, W.5
-
4
-
-
0344450778
-
Direct actions of angiopoietin-1 on human endothelium: Evidence for network stabilization, cell survival, and interaction with other angiogenic growth factors
-
Papapetropoulos A, Garcia-Cardena G, Dengler TJ, Maisonpierre PC, Yancopoulos GD and Sessa WC: Direct actions of angiopoietin-1 on human endothelium: evidence for network stabilization, cell survival, and interaction with other angiogenic growth factors. Lab Invest 79(2): 213-223, 1999.
-
(1999)
Lab Invest
, vol.79
, Issue.2
, pp. 213-223
-
-
Papapetropoulos, A.1
Garcia-Cardena, G.2
Dengler, T.J.3
Maisonpierre, P.C.4
Yancopoulos, G.D.5
Sessa, W.C.6
-
5
-
-
0027197245
-
Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
-
Kim KJ, Li B, Winer J, Armanini M, Gillett N, Phillips HS and Ferrara N: Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature 362(6423): 841-844, 1993.
-
(1993)
Nature
, vol.362
, Issue.6423
, pp. 841-844
-
-
Kim, K.J.1
Li, B.2
Winer, J.3
Armanini, M.4
Gillett, N.5
Phillips, H.S.6
Ferrara, N.7
-
6
-
-
13144262858
-
Paracrine expression of a native soluble vascular endothelial growth factor receptor inhibits tumor growth, metastasis, and mortality rate
-
Goldman CK, Kendall RL, Cabrera G, Soroceanu L, Heike Y, Gillespie GY, Siegal GP, Mao X, Bett AJ, Huckle WR, Thomas KA and Curiel DT: Paracrine expression of a native soluble vascular endothelial growth factor receptor inhibits tumor growth, metastasis, and mortality rate. Proc Natl Acad Sci USA 95(15): 8795-800, 1998.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, Issue.15
, pp. 8795-8800
-
-
Goldman, C.K.1
Kendall, R.L.2
Cabrera, G.3
Soroceanu, L.4
Heike, Y.5
Gillespie, G.Y.6
Siegal, G.P.7
Mao, X.8
Bett, A.J.9
Huckle, W.R.10
Thomas, K.A.11
Curiel, D.T.12
-
9
-
-
0026572345
-
The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor
-
De Vries C, Escobedo JA, Ueno H, Houck K, Ferrara N and Williams LT: The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science 255: 989-991, 1992.
-
(1992)
Science
, vol.255
, pp. 989-991
-
-
De Vries, C.1
Escobedo, J.A.2
Ueno, H.3
Houck, K.4
Ferrara, N.5
Williams, L.T.6
-
10
-
-
0027421333
-
Inhibition of vascular endothelial growth factor activity by an endogenously encoded soluble receptor
-
Kendall RL and Thomas KA: Inhibition of vascular endothelial growth factor activity by an endogenously encoded soluble receptor. Proc Natl Acad Sci USA 90: 10705-10709, 1993.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 10705-10709
-
-
Kendall, R.L.1
Thomas, K.A.2
-
11
-
-
0030582384
-
Identification of a natural soluble form of the vascular endothelial growth factor receptor, FLT-1, and its heterodimerization with KDR
-
Kendall RL, Wang G and Thomas KA: Identification of a natural soluble form of the vascular endothelial growth factor receptor, FLT-1, and its heterodimerization with KDR. Biochem Biophys Res Commun 226: 324-328, 1996.
-
(1996)
Biochem Biophys Res Commun
, vol.226
, pp. 324-328
-
-
Kendall, R.L.1
Wang, G.2
Thomas, K.A.3
-
12
-
-
0028134936
-
Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR
-
Park JE, Chen HH, Winer J, Houck KA and Ferrara N: Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR. J Biol Chem 269: 25646-25654, 1994.
-
(1994)
J Biol Chem
, vol.269
, pp. 25646-25654
-
-
Park, J.E.1
Chen, H.H.2
Winer, J.3
Houck, K.A.4
Ferrara, N.5
-
13
-
-
0026695259
-
Tek, a novel tyrosine kinase gene located on mouse chromosome 4, is expressed in endothelial cells and their presumptive precursors
-
Dumont DJ, Yamaguchi TP, Conlon RA, Rossant J and Breitman ML: Tek, a novel tyrosine kinase gene located on mouse chromosome 4, is expressed in endothelial cells and their presumptive precursors. Oncogene 7: 1471-1480, 1992.
-
(1992)
Oncogene
, vol.7
, pp. 1471-1480
-
-
Dumont, D.J.1
Yamaguchi, T.P.2
Conlon, R.A.3
Rossant, J.4
Breitman, M.L.5
-
14
-
-
0028006242
-
The mouse Tie receptor tyrosine kinase gene: Expression during embryonic angiogenesis
-
Korhonen J, Polvi A, Partanen J and Alitalo K: The mouse Tie receptor tyrosine kinase gene: expression during embryonic angiogenesis. Oncogene 9: 395-403, 1994.
-
(1994)
Oncogene
, vol.9
, pp. 395-403
-
-
Korhonen, J.1
Polvi, A.2
Partanen, J.3
Alitalo, K.4
-
15
-
-
13344295087
-
The Tie receptor tyrosine kinase is expressed by human hematopoietic progenitor cells and by a subset of megakaryocytic cells
-
Batard P, Sansilvestri P, Scheinecker C, Knapp W, Debili N, Vainchenker W, Buhring HJ, Monier MN, Kukk E, Partanen J, Matikainen MT, Alitalo R, Hatzfeld J and Alitalo K: The Tie receptor tyrosine kinase is expressed by human hematopoietic progenitor cells and by a subset of megakaryocytic cells. Blood 87: 2212-2220, 1996.
-
(1996)
Blood
, vol.87
, pp. 2212-2220
-
-
Batard, P.1
Sansilvestri, P.2
Scheinecker, C.3
Knapp, W.4
Debili, N.5
Vainchenker, W.6
Buhring, H.J.7
Monier, M.N.8
Kukk, E.9
Partanen, J.10
Matikainen, M.T.11
Alitalo, R.12
Hatzfeld, J.13
Alitalo, K.14
-
16
-
-
13344259324
-
Predominant expression of a receptor tyrosine kinase, Tie, in hematopoietic stem cells and B cells
-
Hashiyama M, Iwama A, Ohshiro K, Kurozumi K, Yasunaga K, Shimizu Y, Masuho Y, Matsuda I, Yamaguchi N and Suda T: Predominant expression of a receptor tyrosine kinase, Tie, in hematopoietic stem cells and B cells. Blood 87: 93-101, 1996.
-
(1996)
Blood
, vol.87
, pp. 93-101
-
-
Hashiyama, M.1
Iwama, A.2
Ohshiro, K.3
Kurozumi, K.4
Yasunaga, K.5
Shimizu, Y.6
Masuho, Y.7
Matsuda, I.8
Yamaguchi, N.9
Suda, T.10
-
17
-
-
0028122465
-
Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo
-
Dumont DJ, Gradwohl G, Fong GH, Puri MC, Gertsenstein M, Auerbach A and Breitman ML: Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo. Genes Dev 8: 16: 1897-1909, 1994.
-
(1994)
Genes Dev
, vol.8-16
, pp. 1897-1909
-
-
Dumont, D.J.1
Gradwohl, G.2
Fong, G.H.3
Puri, M.C.4
Gertsenstein, M.5
Auerbach, A.6
Breitman, M.L.7
-
18
-
-
0029001244
-
Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation
-
Sato TN, Tozawa Y, Deutsch U, Wolburg-Buchholz K, Fujiwara Y, Gendron-Maguire M, Gridley T, Wolburg H, Risau W and Qin Y: Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation. Nature 376: 6535: 70-74, 1996.
-
(1996)
Nature
, vol.376
, Issue.6535
, pp. 70-74
-
-
Sato, T.N.1
Tozawa, Y.2
Deutsch, U.3
Wolburg-Buchholz, K.4
Fujiwara, Y.5
Gendron-Maguire, M.6
Gridley, T.7
Wolburg, H.8
Risau, W.9
Qin, Y.10
-
19
-
-
0030764063
-
Tie2 expression and phosphorylation in angiogenic and quiescent adult tissues
-
Wong AL, Haroon ZA, Werner S, Dewhirst MW, Greenberg CS and Peters KG: Tie2 expression and phosphorylation in angiogenic and quiescent adult tissues. Circ Res 81: 567-574, 1997.
-
(1997)
Circ Res
, vol.81
, pp. 567-574
-
-
Wong, A.L.1
Haroon, Z.A.2
Werner, S.3
Dewhirst, M.W.4
Greenberg, C.S.5
Peters, K.G.6
-
20
-
-
0030979054
-
Tie2 receptor expression and phosphorylation in cultured cells and mouse tissues
-
Koblizek TI, Runting AS, Stacker SA, Wilks AF, Risau W and Deutsch U: Tie2 receptor expression and phosphorylation in cultured cells and mouse tissues. Eur J Biochem 244: 774-779, 1997.
-
(1997)
Eur J Biochem
, vol.244
, pp. 774-779
-
-
Koblizek, T.I.1
Runting, A.S.2
Stacker, S.A.3
Wilks, A.F.4
Risau, W.5
Deutsch, U.6
-
21
-
-
0029863730
-
Dominant-negative inhibition of FLK-1 suppresses the growth of many tumour types in vivo
-
Millauer B, Longhi MP, Plate KH, Shawver LK, Risau W, Ullrich A and Strawn LM: Dominant-negative inhibition of FLK-1 suppresses the growth of many tumour types in vivo. Cancer Res 56(7): 1615-1620, 1996.
-
(1996)
Cancer Res
, vol.56
, Issue.7
, pp. 1615-1620
-
-
Millauer, B.1
Longhi, M.P.2
Plate, K.H.3
Shawver, L.K.4
Risau, W.5
Ullrich, A.6
Strawn, L.M.7
-
22
-
-
0033168916
-
Two independent mechanisms essential for tumor angiogenesis: Inhibition of human melanoma xenograft growth by interfering with either the vascular endothelial growth factor receptor pathway or the Tie-2 pathway
-
Siemeister G, Schirner M, Weindel K, Reusch P, Menrad A, Marme D and Martiny-Baron G: Two independent mechanisms essential for tumor angiogenesis: inhibition of human melanoma xenograft growth by interfering with either the vascular endothelial growth factor receptor pathway or the Tie-2 pathway. Cancer Res 59(13): 3185-91, 1999.
-
(1999)
Cancer Res
, vol.59
, Issue.13
, pp. 3185-3191
-
-
Siemeister, G.1
Schirner, M.2
Weindel, K.3
Reusch, P.4
Menrad, A.5
Marme, D.6
Martiny-Baron, G.7
-
23
-
-
0032884777
-
Enhanced expression of Tie2, its ligand angiopoietin-1, vascular endothelial growth factor, and CD31 in human non-small cell lung carcinomas
-
Takahama M, Tsutsumi M, Tsujiuchi T, Nezu K, Kushibe K, Taniguchi S, Kotake Y and Konishi Y: Enhanced expression of Tie2, its ligand angiopoietin-1, vascular endothelial growth factor, and CD31 in human non-small cell lung carcinomas. Clin Cancer Res 5: 9: 2506-2510, 1999.
-
(1999)
Clin Cancer Res
, vol.5-9
, pp. 2506-2510
-
-
Takahama, M.1
Tsutsumi, M.2
Tsujiuchi, T.3
Nezu, K.4
Kushibe, K.5
Taniguchi, S.6
Kotake, Y.7
Konishi, Y.8
-
24
-
-
0028670845
-
Enhanced expression of the Tie receptor tyrosine kinase messenger RNA in the vascular endothelium of metastatic melanomas
-
Kaipainen A, Vlaykova T, Hatva E, Bohling T, Jekunen A, Pyrhonen S and Alitalo K: Enhanced expression of the Tie receptor tyrosine kinase messenger RNA in the vascular endothelium of metastatic melanomas. Cancer Res 54(24): 6571-6577, 1994.
-
(1994)
Cancer Res
, vol.54
, Issue.24
, pp. 6571-6577
-
-
Kaipainen, A.1
Vlaykova, T.2
Hatva, E.3
Bohling, T.4
Jekunen, A.5
Pyrhonen, S.6
Alitalo, K.7
-
25
-
-
0030015787
-
Endothelial Tie growth factor receptor provides antigenic marker for assessment of breast cancer angiogenesis
-
Salven P, Joensuu H, Heikkila P, Matikainen MT, Wasenius VM, Alanko A and Alitalo K: Endothelial Tie growth factor receptor provides antigenic marker for assessment of breast cancer angiogenesis. Br J Cancer 74(1): 69-72, 1996.
-
(1996)
Br J Cancer
, vol.74
, Issue.1
, pp. 69-72
-
-
Salven, P.1
Joensuu, H.2
Heikkila, P.3
Matikainen, M.T.4
Wasenius, V.M.5
Alanko, A.6
Alitalo, K.7
-
26
-
-
0032714316
-
Angiopoietin-1 and its receptor tie-2 participate in the regulation of capillary-like tubule formation and survival of endothelial cells
-
Hayes AJ, Huang WQ, Mallah J, Yang D, Lippman ME and Li LY: Angiopoietin-1 and its receptor tie-2 participate in the regulation of capillary-like tubule formation and survival of endothelial cells. Microvasc Res 58(3): 224-37, 1999.
-
(1999)
Microvasc Res
, vol.58
, Issue.3
, pp. 224-237
-
-
Hayes, A.J.1
Huang, W.Q.2
Mallah, J.3
Yang, D.4
Lippman, M.E.5
Li, L.Y.6
-
27
-
-
0030726988
-
Inhibition of tumor angiogenesis using a soluble receptor establishes a role for Tie2 in pathologic vascular growth
-
Lin P, Polverini P, Dewhirst M, Shan S, Rao PS and Peters K: Inhibition of tumor angiogenesis using a soluble receptor establishes a role for Tie2 in pathologic vascular growth. J Clin Invest 100(8): 2072-8, 1997.
-
(1997)
J Clin Invest
, vol.100
, Issue.8
, pp. 2072-2078
-
-
Lin, P.1
Polverini, P.2
Dewhirst, M.3
Shan, S.4
Rao, P.S.5
Peters, K.6
-
28
-
-
0031965353
-
Inhibition of tumor growth by targeting tumor endothelium using a soluble vascular endothelial growth factor receptor
-
Lin P, Sankar S, Shan S, Dewhirst MW, Polverini PJ, Quinn TQ and Peters KG: Inhibition of tumor growth by targeting tumor endothelium using a soluble vascular endothelial growth factor receptor. Cell Growth Differ 9(1): 49-58, 1998.
-
(1998)
Cell Growth Differ
, vol.9
, Issue.1
, pp. 49-58
-
-
Lin, P.1
Sankar, S.2
Shan, S.3
Dewhirst, M.W.4
Polverini, P.J.5
Quinn, T.Q.6
Peters, K.G.7
-
29
-
-
0343091294
-
Soluble flt-1 gene therapy for peritoneal metastases using HVJ-cationic liposomes
-
Mori A, Arii S, Furutani M, Mizumoto M, Uchida S, Furuyama H, Kondo Y, Gorrin-Rivas MJ, Furumoto K, Kaneda Y and Imamura M: Soluble flt-1 gene therapy for peritoneal metastases using HVJ-cationic liposomes. Gene Ther 7(12): 1027-33, 2000.
-
(2000)
Gene Ther
, vol.7
, Issue.12
, pp. 1027-1033
-
-
Mori, A.1
Arii, S.2
Furutani, M.3
Mizumoto, M.4
Uchida, S.5
Furuyama, H.6
Kondo, Y.7
Gorrin-Rivas, M.J.8
Furumoto, K.9
Kaneda, Y.10
Imamura, M.11
-
30
-
-
0034655246
-
Suppression of tumor angiogenesis and growth by gene transfer of a soluble form of vascular endothelial growth factor receptor into a remote organ
-
Takayama K, Ueno H, Nakanishi Y, Sakamoto T, Inoue K, Shimizu K, Oohashi H and Hara N: Suppression of tumor angiogenesis and growth by gene transfer of a soluble form of vascular endothelial growth factor receptor into a remote organ. Cancer Res 15; 60(8): 2169-77, 2000.
-
(2000)
Cancer Res
, vol.60
, Issue.8
, pp. 2169-2177
-
-
Takayama, K.1
Ueno, H.2
Nakanishi, Y.3
Sakamoto, T.4
Inoue, K.5
Shimizu, K.6
Oohashi, H.7
Hara, N.8
-
31
-
-
0033060416
-
In vivo and ex vivo gene therapy strategies to treat tumors using adenovirus gene transfer vectors
-
Crystal RG: In vivo and ex vivo gene therapy strategies to treat tumors using adenovirus gene transfer vectors. Cancer Chemother Pharmacol 43 Suppl: S90-9, 1999.
-
(1999)
Cancer Chemother Pharmacol
, vol.43
, Issue.SUPPL.
-
-
Crystal, R.G.1
-
32
-
-
0033570185
-
Angiopoietin-1 and -2 coiled coil domains mediate distinct homooligomerization patterns, but fibrinogen-like domains mediate ligand activity
-
Procopio WN, Pelavin PI, Lee WM and Yeilding NM: Angiopoietin-1 and -2 coiled coil domains mediate distinct homooligomerization patterns, but fibrinogen-like domains mediate ligand activity. J Biol Chem 274(42): 30196-30201, 1999.
-
(1999)
J Biol Chem
, vol.274
, Issue.42
, pp. 30196-30201
-
-
Procopio, W.N.1
Pelavin, P.I.2
Lee, W.M.3
Yeilding, N.M.4
-
33
-
-
0032504752
-
Tie2 receptor ligands, angiopoietin-1 and angiopoietin-2, modulate VEGF-induced postnatal neovascularization
-
Asahara T, Chen D, Takahashi T, Fujikawa K, Kearney M, Magner M, Yancopoulos GD and Isner JM: Tie2 receptor ligands, angiopoietin-1 and angiopoietin-2, modulate VEGF-induced postnatal neovascularization. Circ Res 83(3): 233-240, 1998.
-
(1998)
Circ Res
, vol.83
, Issue.3
, pp. 233-240
-
-
Asahara, T.1
Chen, D.2
Takahashi, T.3
Fujikawa, K.4
Kearney, M.5
Magner, M.6
Yancopoulos, G.D.7
Isner, J.M.8
-
34
-
-
15144358851
-
Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis
-
Maisonpierre PC, Suri C, Jones PF, Bartunkova S, Wiegand SJ, Radziejewski C, Compton D, McClain J, Aldrich TH, Papadopoulos N, Daly TJ, Davis S, Sato TN and Yancopoulos GD: Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis. Science 277(5322): 55-60, 1997.
-
(1997)
Science
, vol.277
, Issue.5322
, pp. 55-60
-
-
Maisonpierre, P.C.1
Suri, C.2
Jones, P.F.3
Bartunkova, S.4
Wiegand, S.J.5
Radziejewski, C.6
Compton, D.7
McClain, J.8
Aldrich, T.H.9
Papadopoulos, N.10
Daly, T.J.11
Davis, S.12
Sato, T.N.13
Yancopoulos, G.D.14
-
35
-
-
0031964710
-
Expression of Tie2/Tek in breast tumour vasculature provides a new marker for evaluation of tumour angiogenesis
-
Peters KG, Coogan A, Berry D, Marks J, Iglehart JD, Kontos CD, Rao P, Sankar S and Trogan E: Expression of Tie2/Tek in breast tumour vasculature provides a new marker for evaluation of tumour angiogenesis. Br J Cancer 77(1): 51-56, 1998.
-
(1998)
Br J Cancer
, vol.77
, Issue.1
, pp. 51-56
-
-
Peters, K.G.1
Coogan, A.2
Berry, D.3
Marks, J.4
Iglehart, J.D.5
Kontos, C.D.6
Rao, P.7
Sankar, S.8
Trogan, E.9
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