The tie receptor tyrosine kinase is expressed by human hematopoietic progenitor cells and by a subset of megakaryocytic cells

Blood

Volumn 87, Issue 6, 1996, Pages 2212-2220

  Batard, Pascal ^b   Sansilvestri, Patricia ^b   Scheinecker, Clemens ^b   Knapp, Walter ^b   Debili, Najet ^b   Vainchenker, William ^b   Bühring, Hans Jörg ^b   Monier, Marie Noelle ^b   Kukk, Eola ^b   Partanen, Juha ^b   Matikainen, Marja Terttu ^b   Alitalo, Riitta ^b   Hatzfeld, Jacques ^b   Alitalo, Kari ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH FACTOR RECEPTOR; PROTEIN TYROSINE KINASE;

ARTICLE; CELL DIFFERENTIATION; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; MEGAKARYOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 13344295087     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v87.6.2212.bloodjournal8762212     Document Type: Article

References (49)

1. van der Geer P, Hunter T, Lindberg RA: Receptor protein-tyrosine kinases and their signal transduction pathways. Annu Rev Cell Biol 10:251, 1994
2. Papayannopoulou T, Raines E, Collins S, Nakamoto B, Tweeddale M, Ross R: Constitutive and inducible secretion of platelet derived growth factor analogs by human leukemic cell lines coexpressing erythroid and megekaryocytic markers. J Clin Invest 79:859, 1987
3. Tetteroo P, Massaro F, Mulder A, Schreuder-van-Gelder R, von dem Borne A: Megakaryoblastic differentiation of proerythroblastic K-562 cell-line cells. Leuk Res 8:197, 1984
4. Partanen J, Mäkelä TP, Alitalo R, Lehväslaiho H, Alitalo K: Putative tyrosine kinases expressed in K-562 human leukemia cells. Proc Natl Acad Sci USA 87:8913, 1990
5. Partanen J, Armstrong E, Mäkelä TP, Korhonen J, Sandberg M, Renkonen R, Knuutila S, Huebner K, Alitalo K: A novel endothelial cell surface receptor tyrosine kinase with extracellular epidermal growth factor homology domains. Mol Cell Biol 12:1698, 1992
6. Vainikka S, Partanen J, Bellosta P, Coulier F, Basilico C, Jaye M, Alitalo K: Fibroblast growth factor receptor-4 shows novel features in genomic structure, ligand binding and signal transduction. EMBO J 11:4273, 1992
7. Aprelikova O, Pajusola K, Partanen J, Armstrong E, Alitalo R, Bailey SK, McMahon J, Wasmuth J, Huebner K, Alitalo K: FLT4, a novel class III receptor tyrosine kinase in chromosome 5q33-qter. Cancer Res 52:746, 1992
8. Pajusola K, Aprelikova O, Korhonen J, Kaipainen A, Pertovaara L, Alitalo R, Alitalo K: FLT4 receptor tyrosine kinase contains seven immunoglobulin-like loops and is expressed in multiple human tissues and cell lines. Cancer Res 52:5738, 1992
9. Polvi A, Armstrong E, Lai C, Lemke G, Huebner K, Spritz R, Guida L, Nicholls R, Alitalo K: The human Tyro3 gene and pseudogene are located in chromosome 15q14-q25. Gene 134:289, 1993
10. Tamagnone L, Partanen J, Armstrong E, Lasola J, Ohgami K, Tazunoki T, LaForgia S, Huebner K, Alitalo K: The human ryk cDNA sequence predicts a protein containing two putative transmembrane segments and a tyrosine kinase catalytic domain. Oncogene 8:2009, 1993
11. Armstrong E, Vainikka S, Partanen J, Korhonen J, Alitalo R: Expression of fibroblast growth factor receptors in human leukemia cells. Cancer Res 52:2004, 1992
12. Armstrong E, Partanen J, Cannizzaro L, Huebner K, Alitalo K: Localization of the fibroblast growth factor receptor-4 gene to choromosome region 5q33-qter. Genes Chromosome Cancer 4 94, 1992
13. Armstrong E, Korhonen J, Silvennoinen O, Cleveland JL, Lieberman MA, Alitalo R: Expression of tie receptor tyrosine kinase in leukemia cell lines. Leukemia 7:1585, 1993
14. Dumont DJ, Gradwohl GJ, Fong G-H, Auerbach R, Breitman ML: The endothelial-specific receptor tyrosine kinase, tek, is a member of a new subfamily of receptors. Oncogene 8:1293, 1993
15. Korhonen J, Partanen J, Armstrong E, Vaahtokari A, Elenius K, Jalkanen M. Alitalo K: Enhanced expression of the tie receptor tyrosine kinase in endothelial cells during neovascularization. Blood 80:2548, 1992
16. Iwama A, Hamaguchi I, Hashiyama M, Murayama Y, Yasunaga K, Suda T: Molecular cloning and characterization of mouse TIE and TEK receptor tyrosine kinase genes and their expression in hematopoietic stem cells. Biochem Biophys Res Commun 195:301, 1993
17. Hatzfeld J, Batard P, Cardoso AA, Li ML, Hatzfeld A: Purification and in vitro assay of early human hematopoietic progenitors, in Freshney R, Pragnell IB, Freshney MG (eds): Culture of Hematopoietic Cells. New York, NY, Wiley, 1994, p 205
18. Mitjavila MT, Vinci G, Villeval JL, Kieffer N, Henri A, Testa U, Breton-Gorius J, Vainchenker W: Human platelet alpha granules contain a non specific inhibitor of megakaryocyte colony formation: Its relationship to type β transforming growth factor (TGF β). J Cell Biol 134:93, 1988
19. Majdic O, Stöckl J, Pickl WF, Bohuslav J, Strobl H, Scheinecker C, Stockinger H, Knapp W: Signalling and induction of enhanced cytoadhesivness via the hematopoietic progenitor cell surface molecule CD34. Blood 83:1226, 1994
20. + normal human hematopoietic cells. Blood 82:2069, 1993
21. Panterne B, Zhou YQ, Hatzfeld J, Li ML, Lévesque JP, Clark SC, Hatzfeld A: CSF-1 control of C-FMS expression in normal human bone marrow progenitors. J Cell Physiol 155:282, 1993
22. Hatva E, Kaipainen A, Mentula P, Jääskeläinen J, Paetau A, Haltia M, Alitalo K: Expression of endothelial cell-specific receptor tyrosine kinases and growth factors in human brain tumors. Am J Pathol 146:368, 1995
23. Daley G, Van Etten R, Baltimore D: Induction of chronic myelogeneous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome. Science 247:824, 1990
24. Mustonen T, Alitalo K: Endothelial receptor tyrosine kinases involved in angiogenesis. J Cell Biol 129:895, 1995
25. - progenitor cells. Blood 77:1218, 1991
26. - umbilical cord blood cells reveals their potentiality to engraft adults. Proc Natl Acad Sci USA 90:8707, 1993
27. - hematopoietic stem cells. Blood 83:1515, 1994
28. Baum CM, Weissman IL, Tsukamoto AL, Buckle AM, Peault B: Isolation of a candidate human stem cell population. Proc Natl Acad Sci USA 89:2804, 1992
29. Craig W, Kay R, Ctuler RL, Lansdorp PM: Expression of Thy-1 on human hematopoietic progenitor cells. J Exp Med 177:1331, 1993
30. - bone marrow cells contain progenitor cells capable of self-renewal, multilineage differentiation, and long-term in vitro hematopoiesis. Blood Cells 17:287, 1991
31. Sutherland HJ, Eaves CJ, Eaves AC, Dragowska W, Lansdorp PM: Characterization and partial purification of human marrow cells capable of nitiating long-term hematopoiesis in vitro. Blood 74:1563, 1989
32. Ratajczak MZ, Luger SM, De Riel K, Abraham J, Calabretta B, Gewirtz AM: Role of the KIT protooncogene in normal and malignant human hematopoiesis. Proc Natl Acad Sci USA 89:1710, 1992
33. Katayama N, Shih JP, Nishikawa SI, Kina T, Clark SC, Ogawa M: Stage-specific expression of c-kit protein by murine hematopoietic progenitors. Blood 82:2353, 1993
34. high cells. Blood 82:3283, 1993
35. low cells in which anti-TGF-β upmodulates c-kit. Blood 86:1729, 1995
36. Sherr CJ, Rettenmier CW, Sacca R, Roussel MF, Look AT, Stanley ER: The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF-1. Cell 41:665, 1985
37. Chabot B, Stephenson DA, Chapman VM, Besmer P, Bernstein A: The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus. Nature 335:88, 1988
38. Yarden Y, Kuang WJ, Yang FT, Coussens L, Munemitsu S, Dull TJ, Chen E, Schlessinger J, Francke U, Ullrich A: Human proto-oncogene c-kit: A new cell surface receptor tyrosine kinase for an unidentified ligand. EMBO J 6:3341, 1987
39. Matthews W, Jordan CT, Wiegand GW, Pardoll D, Lemischka IR: A receptor tyrosine kinase specific to hematopoietic stem and progenitor cell-enriched population. Cell 65:1143, 1991
40. Oelrichs RB, Reid HH, Bernard O, Ziemiecki A, Wilks AF: NYK/FLK-1: A putative receptor protein tyrosine kinase isolated from ElO embryonic neuroepithelium is expressed in endothelial cells of the developing embryo. Oncogene 8:11, 1992
41. Terman BI, Dougher-Vermazen M, Carrion ME, Dimitrov D, Armellino DC, Gospodarowicz D, Böhlen P: Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor. Biochem Biophys Res Commun 187:1579, 1992
42. Matthews W, Jordan CT, Gavin M, Jenkins NA, Copeland NG, Lemischka IR: A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoetic cells and exhibiting close genetic linkage to c-kit. Proc Natl Acad Sci USA 88:9026, 1991
43. Shalaby F, Rossant J, Yamaguchi TP, Gertsenstein, M., Wu, X-F, Breitman ML, Schuh AC: Failure of blood island formation and vasculogenesis in FLK-1 deficient mice. Nature 376:62, 1995
44. Fong G-H, Rossant J, Gertsenstein, M., Breitman ML: Role of Flt-1 receptor tyrosine kinase in regulating assembly of vascular endothelium. Nature 376:66, 1995
45. Dumont DJ, Yamaguchi TP, Conlon RA, Rossant J, Breitman ML: tek, a novel tyrosine kinase gene located on mouse chromosome 4, is expressed in endothelial cells and their presumptive precursors. Oncogene 7:1471, 1992
46. Puri M, Rossant J, Alitalo K, Bernstein A, Partanen J: The receptor tyrosine kinase TIE is required for the integrity and survival of vascular endothelial cells. EMBO J 14:5884, 1995
47. Dumont DJ, Gradwohl G, Fong G-H, Puri MC, Gertsenstein M, Auerbach A, Breitman ML: Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo. Genes Dev 8:1897, 1994
48. Sato TN, Tozawa Y, Deutsch U, Wolburg-Buchholz K, Fujiwara Y, Gendron-Maguire M, Gridley T, Wolburg H, Risau W, Qin Y: Tie1 and Tie2 receptor tyrosine kinases are important for distinct aspects of blood vessel formation. Nature 376:70, 1995
49. Hashiyama H, Iwama A, Ohshiro K, Kurozumi K, Yasunaga K, Shimizu Y, Masuho Y, Matsuda I, Yamaguchi N, Suda T: Predominant expression of a receptor tyrosine kinase, tie in hematopoietic stem cells and B cells Blood (in press)