-
1
-
-
0035003785
-
PDGF-D is a specific and protease-activated ligand for the PDGF beta receptor
-
Bergsten E, Uutela M, Li X, Pietras K, Heldin C-H, Ostman A, Alitalo K, Eriksson U. PDGF-D is a specific and protease-activated ligand for the PDGF beta receptor. Nat Cell Biol. 2000;3:512-516.
-
(2000)
Nat Cell Biol
, vol.3
, pp. 512-516
-
-
Bergsten, E.1
Uutela, M.2
Li, X.3
Pietras, K.4
Heldin, C.-H.5
Ostman, A.6
Alitalo, K.7
Eriksson, U.8
-
2
-
-
0035005849
-
PDGF-D, a new protease-activated growth factor
-
LaRochelle WJ, Jeffers M, McDonald WF, Chillakuru RA, Giese NA, Lokker NA, Sullivan C, Boldog FL, Yang M, Vemet C, Burgess CE, Fernandes E, Deegler LL, Rittman B, Shimkets J, Shimkets RA, Rothberg JM, Lichenstein HS. PDGF-D, a new protease-activated growth factor. Nat Cell Biol. 2001;3:517-521.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 517-521
-
-
LaRochelle, W.J.1
Jeffers, M.2
McDonald, W.F.3
Chillakuru, R.A.4
Giese, N.A.5
Lokker, N.A.6
Sullivan, C.7
Boldog, F.L.8
Yang, M.9
Vemet, C.10
Burgess, C.E.11
Fernandes, E.12
Deegler, L.L.13
Rittman, B.14
Shimkets, J.15
Shimkets, R.A.16
Rothberg, J.M.17
Lichenstein, H.S.18
-
3
-
-
0033776193
-
PDGF-C is a new protease-activated ligand for the PDGF alpha receptor
-
Li X, Porten A, Aase K, Karlsson L, Abramsson A, Uutela M, Backstrom G, Hellstrom M, Bostrom H, Li H, Soriano P, Betsholtz C, Heldin C-H, Alitalo K, Ostman A, Eriksson U. PDGF-C is a new protease-activated ligand for the PDGF alpha receptor. Nat Cell Biol. 2000;2:302-309.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 302-309
-
-
Li, X.1
Porten, A.2
Aase, K.3
Karlsson, L.4
Abramsson, A.5
Uutela, M.6
Backstrom, G.7
Hellstrom, M.8
Bostrom, H.9
Li, H.10
Soriano, P.11
Betsholtz, C.12
Heldin, C.-H.13
Alitalo, K.14
Ostman, A.15
Eriksson, U.16
-
4
-
-
0034989658
-
Developmental roles of platelet-derived growth factors
-
Betsholtz C, Karlsson L, Lindahl P. Developmental roles of platelet-derived growth factors. BioEssays. 2001;23:494-507.
-
(2001)
BioEssays
, vol.23
, pp. 494-507
-
-
Betsholtz, C.1
Karlsson, L.2
Lindahl, P.3
-
5
-
-
0023968858
-
Expression and developmental control of platelet-derived growth factor A-chain and B-chain/Sis genes in rat aortic smooth muscle cells
-
Majesky MW, Benditt EP, Schwartz SM. Expression and developmental control of platelet-derived growth factor A-chain and B-chain/Sis genes in rat aortic smooth muscle cells. Proc Natl Acad Sci USA. 1988;85:1524-1528.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 1524-1528
-
-
Majesky, M.W.1
Benditt, E.P.2
Schwartz, S.M.3
-
6
-
-
0023927488
-
Production of platelet-derived growth factor-like mitogen by smooth-muscle cells from human atheroma
-
Libby P, Warner SJ, Salomon RN, Birinyi LK. Production of platelet-derived growth factor-like mitogen by smooth-muscle cells from human atheroma. N Engl J Med. 1988;318:1493-1498.
-
(1988)
N Engl J Med
, vol.318
, pp. 1493-1498
-
-
Libby, P.1
Warner, S.J.2
Salomon, R.N.3
Birinyi, L.K.4
-
7
-
-
0342596004
-
Platelet-derived growth factor gene expression in human atherosclerotic plaques and normal artery wall
-
Barrett TB, Benditt EP. Platelet-derived growth factor gene expression in human atherosclerotic plaques and normal artery wall. Proc Natl Acad Sci USA. 1988;85:2810-2814.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 2810-2814
-
-
Barrett, T.B.1
Benditt, E.P.2
-
8
-
-
0029781015
-
In situ detection of platelet-derived growth factor-A and -B chain mRNA in human coronary arteries after percutaneous transluminal coronary angioplasty
-
Ueda M, Becker AE, Kasayuki N, Kojima, Morita Y, Tanaka S. In situ detection of platelet-derived growth factor-A and -B chain mRNA in human coronary arteries after percutaneous transluminal coronary angioplasty. Am J Pathol. 1996;149:831-843.
-
(1996)
Am J Pathol
, vol.149
, pp. 831-843
-
-
Ueda, M.1
Becker, A.E.2
Kasayuki, N.3
Kojima4
Morita, Y.5
Tanaka, S.6
-
9
-
-
0024007666
-
Binding of different dimeric forms of PDGF to human fibroblasts: Evidence for two separate receptor types
-
Heldin C-H, Backstrom G, Ostman A, Hammacher A, Ronnstrand L, Rubin K, Nister M, Westermark B. Binding of different dimeric forms of PDGF to human fibroblasts: evidence for two separate receptor types. EMBO J. 1988;7:1387-1393.
-
(1988)
EMBO J
, vol.7
, pp. 1387-1393
-
-
Heldin, C.-H.1
Backstrom, G.2
Ostman, A.3
Hammacher, A.4
Ronnstrand, L.5
Rubin, K.6
Nister, M.7
Westermark, B.8
-
10
-
-
0022447025
-
cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumor cell lines
-
Betsholtz C, Johnsson A, Heldin C-H, Westermark B, Lind P, Urdea MS, Eddy R, Shows TB, Philpott K, Mellor AL, Knott TJ, Scott J. cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumor cell lines. Nature. 1986;320:695-699.
-
(1986)
Nature
, vol.320
, pp. 695-699
-
-
Betsholtz, C.1
Johnsson, A.2
Heldin, C.-H.3
Westermark, B.4
Lind, P.5
Urdea, M.S.6
Eddy, R.7
Shows, T.B.8
Philpott, K.9
Mellor, A.L.10
Knott, T.J.11
Scott, J.12
-
11
-
-
0023874564
-
Platelet-derived growth factor A chain: Gene structure, chromosomal location, and basis for alternative mRNA splicing
-
Bonthron DT, Morton CC, Orkin SH, Collins T. Platelet-derived growth factor A chain: gene structure, chromosomal location, and basis for alternative mRNA splicing. Proc Natl Acad Sci USA. 1988;85:1492-1496.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 1492-1496
-
-
Bonthron, D.T.1
Morton, C.C.2
Orkin, S.H.3
Collins, T.4
-
12
-
-
0028788227
-
Interplay of Sp1 and Egr-1 in the proximal platelet-derived growth factor A-chain promoter in cultured vascular endothelial cells
-
Khachigian LM, Williams AJ, Collins T. Interplay of Sp1 and Egr-1 in the proximal platelet-derived growth factor A-chain promoter in cultured vascular endothelial cells. J Biol Chem. 1995;270:27679-27686.
-
(1995)
J Biol Chem
, vol.270
, pp. 27679-27686
-
-
Khachigian, L.M.1
Williams, A.J.2
Collins, T.3
-
13
-
-
0031458309
-
Egr-1 is activated in endothelial cells exposed to fluid shear stress and interacts with a novel shear-stress response element in the PDGF A-chain promoter
-
Khachigian LM, Anderson KA, Halnon NJ, Resnick N, Gimbrone Ma, Collins T. Egr-1 is activated in endothelial cells exposed to fluid shear stress and interacts with a novel shear-stress response element in the PDGF A-chain promoter. Arterioscler Thromb Vasc Biol. 1997;17:2280-2286.
-
(1997)
Arterioscler Thromb Vasc Biol
, vol.17
, pp. 2280-2286
-
-
Khachigian, L.M.1
Anderson, K.A.2
Halnon, N.J.3
Resnick, N.4
Gimbrone, M.A.5
Collins, T.6
-
14
-
-
0030873077
-
FGF-1-induced platelet-derived growth factor-A chain gene expression in endothelial cells involves transcriptional activation by early growth response factor-1
-
Delbridge GJ, Khachigian LM. FGF-1-induced platelet-derived growth factor-A chain gene expression in endothelial cells involves transcriptional activation by early growth response factor-1. Circ Res. 1997;81:282-288.
-
(1997)
Circ Res
, vol.81
, pp. 282-288
-
-
Delbridge, G.J.1
Khachigian, L.M.2
-
15
-
-
0030882343
-
Inducible PDGF-A chain transcription in smooth muscle cells is mediated by Egr-1 displacement of Sp1 and Sp3
-
Silverman ES, Khachigian, LM, Lindner V, Williams AJ, Collins T. Inducible PDGF-A chain transcription in smooth muscle cells is mediated by Egr-1 displacement of Sp1 and Sp3. Am J Physiol. 1997;273: H1415-H1426.
-
(1997)
Am J Physiol
, vol.273
-
-
Silverman, E.S.1
Khachigian, L.M.2
Lindner, V.3
Williams, A.J.4
Collins, T.5
-
16
-
-
0026464717
-
Human platelet-derived growth factor A chain is transcriptionally repressed by the Wilms tumor suppressor WT1
-
Gashler AL, Bonthron DT, Madden SL, Rauscher FJ, Collins T, Sukhatme VP. Human platelet-derived growth factor A chain is transcriptionally repressed by the Wilms tumor suppressor WT1. Proc Natl Acad Sci USA. 1992;89:10984-10988.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 10984-10988
-
-
Gashler, A.L.1
Bonthron, D.T.2
Madden, S.L.3
Rauscher, F.J.4
Collins, T.5
Sukhatme, V.P.6
-
17
-
-
0026526495
-
The Wilms' tumor gene product, WT-1, represses transcription of the platelet-derived growth factor A-chain gene
-
Wang ZY, Madden SL, Deuel TF, Rauscher FJ. The Wilms' tumor gene product, WT-1, represses transcription of the platelet-derived growth factor A-chain gene. J Biol Chem. 1992;267:21999-22002.
-
(1992)
J Biol Chem
, vol.267
, pp. 21999-22002
-
-
Wang, Z.Y.1
Madden, S.L.2
Deuel, T.F.3
Rauscher, F.J.4
-
18
-
-
0033546366
-
GC factor 2 represses platelet-derived growth factor A-chain gene transcription and is itself induced by arterial injury
-
Khachigian LM, Santiago FS, Rafty LA, Chan LW, Delbridge GJ, Bobik A, Collins T, Johnson AC. GC factor 2 represses platelet-derived growth factor A-chain gene transcription and is itself induced by arterial injury. Circ Res. 1999;84:1258-1267.
-
(1999)
Circ Res
, vol.84
, pp. 1258-1267
-
-
Khachigian, L.M.1
Santiago, F.S.2
Rafty, L.A.3
Chan, L.W.4
Delbridge, G.J.5
Bobik, A.6
Collins, T.7
Johnson, A.C.8
-
19
-
-
0036469899
-
NF1/X represses PDGF A-chain transcription by interacting with Sp1 and antagonizing Sp1 occupancy of the promoter
-
Rafty LA, Santiago FS, Khachigian LM. NF1/X represses PDGF A-chain transcription by interacting with Sp1 and antagonizing Sp1 occupancy of the promoter. EMBO J. 2002;21:334-343.
-
(2002)
EMBO J
, vol.21
, pp. 334-343
-
-
Rafty, L.A.1
Santiago, F.S.2
Khachigian, L.M.3
-
20
-
-
0025120749
-
The ETS-domain: A new DNA-binding motif that recognizes a purine-rich core DNA sequence
-
Karim FD, Urness LD, Thummel CS, Klemsz MJ, McKercher SR, Celada A, Van Beveren C, Maki RA, Gunther CV, Nye JA. The ETS-domain: a new DNA-binding motif that recognizes a purine-rich core DNA sequence. Genes Dev. 1990;4:1451-1453.
-
(1990)
Genes Dev
, vol.4
, pp. 1451-1453
-
-
Karim, F.D.1
Urness, L.D.2
Thummel, C.S.3
Klemsz, M.J.4
McKercher, S.R.5
Celada, A.6
Van Beveren, C.7
Maki, R.A.8
Gunther, C.V.9
Nye, J.A.10
-
21
-
-
0026531907
-
Identification of nucleotide preferences in DNA sequences recognized specifically by c-Ets-1 protein
-
Woods DB, Ghysdael J, Owen MJ. Identification of nucleotide preferences in DNA sequences recognized specifically by c-Ets-1 protein. Nucleic Acids Res. 1992;20:699-704.
-
(1992)
Nucleic Acids Res
, vol.20
, pp. 699-704
-
-
Woods, D.B.1
Ghysdael, J.2
Owen, M.J.3
-
22
-
-
0030478724
-
Ets-1 regulates angio-genesis by inducing the expression of urokinase-type plasminogen activator and matrix mettaloproteinase-1 and the migration of vascular endothelial cells
-
Iwasaka C, Tanaka K, Abe M, Sato Y. Ets-1 regulates angio-genesis by inducing the expression of urokinase-type plasminogen activator and matrix mettaloproteinase-1 and the migration of vascular endothelial cells. J Cell Physiol. 1996;169:522-531.
-
(1996)
J Cell Physiol
, vol.169
, pp. 522-531
-
-
Iwasaka, C.1
Tanaka, K.2
Abe, M.3
Sato, Y.4
-
23
-
-
0031885897
-
Ets-1 is an early response gene activated by ET-1 and PDGF-BB in vascular smooth muscle cells
-
Naito S, Shimizu S, Maeda S, Wang J, Paul R, Fagin JA. Ets-1 is an early response gene activated by ET-1 and PDGF-BB in vascular smooth muscle cells. Am J Physiol. 1998;274:C472-C480.
-
(1998)
Am J Physiol
, vol.274
-
-
Naito, S.1
Shimizu, S.2
Maeda, S.3
Wang, J.4
Paul, R.5
Fagin, J.A.6
-
24
-
-
0031873601
-
Induction of Ets-1 in endothelial cells during reendothelialization after denuding injury
-
Tanaka K, Oda N, Iwasaka C, Abe M, Sato Y. Induction of Ets-1 in endothelial cells during reendothelialization after denuding injury. J Cell Physiol. 1998;176:235-244.
-
(1998)
J Cell Physiol
, vol.176
, pp. 235-244
-
-
Tanaka, K.1
Oda, N.2
Iwasaka, C.3
Abe, M.4
Sato, Y.5
-
25
-
-
0032479139
-
The Ets-1 and Ets-2 transcription factors activate the promoters for invasion-associated urokinase and collagenase genes in response to epidermal growth factor
-
Watabe T, Yoshida K, Shindoh M, Kaya M, Fujikawa K, Sato H, Seiki M, Ishii S, Fujinaga K. The Ets-1 and Ets-2 transcription factors activate the promoters for invasion-associated urokinase and collagenase genes in response to epidermal growth factor. Int J Cancer. 1998;77:128-137.
-
(1998)
Int J Cancer
, vol.77
, pp. 128-137
-
-
Watabe, T.1
Yoshida, K.2
Shindoh, M.3
Kaya, M.4
Fujikawa, K.5
Sato, H.6
Seiki, M.7
Ishii, S.8
Fujinaga, K.9
-
26
-
-
0035201123
-
Peroxisome proliferator-activated receptor-gamma ligands inhibit nuclear but not cytosolic extracellular signal-regulated kinase/mitogen-activated protein kinase-regulated steps in vascular smooth muscle cell migration
-
Goetze S, Kintscher U, Kim S, Meehan WP, Kaneshiro K, Collins AR, Fleck E, Hsueh WA, Law RE. Peroxisome proliferator-activated receptor-gamma ligands inhibit nuclear but not cytosolic extracellular signal-regulated kinase/mitogen-activated protein kinase-regulated steps in vascular smooth muscle cell migration. J Cardiovasc Pharmacol. 2001;38:909-921.
-
(2001)
J Cardiovasc Pharmacol
, vol.38
, pp. 909-921
-
-
Goetze, S.1
Kintscher, U.2
Kim, S.3
Meehan, W.P.4
Kaneshiro, K.5
Collins, A.R.6
Fleck, E.7
Hsueh, W.A.8
Law, R.E.9
-
27
-
-
0342378191
-
Expression of phenotype- and proliferation-related genes in rat aortic smooth muscle cells in primary culture
-
Hultgardh-Nilsson A, Lovdahl C, Blomgren K, Kallin B, Thyberg J. Expression of phenotype- and proliferation-related genes in rat aortic smooth muscle cells in primary culture. Cardiovasc Res. 1997;34:418-430.
-
(1997)
Cardiovasc Res
, vol.34
, pp. 418-430
-
-
Hultgardh-Nilsson, A.1
Lovdahl, C.2
Blomgren, K.3
Kallin, B.4
Thyberg, J.5
-
28
-
-
0029869801
-
Regulated expression of the ets-1 transcription factor in vascular smooth muscle cells in vivo and in vitro
-
Hultgardh-Nilsson A, Cercek B, Wang S, Naito S, Lovdahl C, Sharifi B, Forrester JS, Fagin JA. Regulated expression of the ets-1 transcription factor in vascular smooth muscle cells in vivo and in vitro. Circ Res. 1996;78:589-595.
-
(1996)
Circ Res
, vol.78
, pp. 589-595
-
-
Hultgardh-Nilsson, A.1
Cercek, B.2
Wang, S.3
Naito, S.4
Lovdahl, C.5
Sharifi, B.6
Forrester, J.S.7
Fagin, J.A.8
-
29
-
-
0037183972
-
Ets-1 positively regulates Fas ligand transcription via cooperative interaction with Sp1
-
Kavurma MM, Bobryshev Y, Khachigian LM. Ets-1 positively regulates Fas ligand transcription via cooperative interaction with Sp1. J Biol Chem. 2002;277:36244-36252.
-
(2002)
J Biol Chem
, vol.277
, pp. 36244-36252
-
-
Kavurma, M.M.1
Bobryshev, Y.2
Khachigian, L.M.3
-
30
-
-
0033588226
-
Angiotensin II (ATII)-inducible platelet-derived growth factor A-chain gene expression is p42/44 extracellular signal-regulated kinase-1/2 and egr-1-dependent and mediated via the ATii type 1 but not type 2 receptor
-
Day FL, Rafty LA, Chesterman CN, Khachigian LM. Angiotensin II (ATII)-inducible platelet-derived growth factor A-chain gene expression is p42/44 extracellular signal-regulated kinase-1/2 and egr-1-dependent and mediated via the ATii type 1 but not type 2 receptor. J Biol Chem. 1999;274:23726-23733.
-
(1999)
J Biol Chem
, vol.274
, pp. 23726-23733
-
-
Day, F.L.1
Rafty, L.A.2
Chesterman, C.N.3
Khachigian, L.M.4
-
31
-
-
0035798676
-
Induction of the transcriptional repressor Yin Yang-1 by vascular cell injury: Autocrine/paracrine role of endogenous fibroblast growth factor-2
-
Santiago FS, Lowe HC, Bobryshev YV, Khachigian LM. Induction of the transcriptional repressor Yin Yang-1 by vascular cell injury: autocrine/paracrine role of endogenous fibroblast growth factor-2. J Biol Chem. 2001;276:41143-41149.
-
(2001)
J Biol Chem
, vol.276
, pp. 41143-41149
-
-
Santiago, F.S.1
Lowe, H.C.2
Bobryshev, Y.V.3
Khachigian, L.M.4
-
32
-
-
0000357398
-
Cloning and expression of rat platelet-derived growth factor A-chain
-
Xia Y, Feng L, Tang WW, Wilson CB. Cloning and expression of rat platelet-derived growth factor A-chain. J Am Soc Nephrol. 1992;3:622.
-
(1992)
J Am Soc Nephrol
, vol.3
, pp. 622
-
-
Xia, Y.1
Feng, L.2
Tang, W.W.3
Wilson, C.B.4
-
33
-
-
0029050865
-
A subpopulation of smooth muscle cells in injured rat arteries expresses platelet-derived growth factor-B chain mRNA
-
Lindner V, Giachelli CM, Schwartz SM, Reidy MA. A subpopulation of smooth muscle cells in injured rat arteries expresses platelet-derived growth factor-B chain mRNA. Circ Res. 1995;76:951-957.
-
(1995)
Circ Res
, vol.76
, pp. 951-957
-
-
Lindner, V.1
Giachelli, C.M.2
Schwartz, S.M.3
Reidy, M.A.4
-
34
-
-
0031885897
-
Ets-1 is an early response gene activated by ET-1 and PDGF-BB in vascular smooth muscle cells
-
Naito S, Shimizu S, Maeda S, Wang J, Paul R, Fagin JA. Ets-1 is an early response gene activated by ET-1 and PDGF-BB in vascular smooth muscle cells. Am J Physiol. 1998;274:C472-C480.
-
(1998)
Am J Physiol
, vol.274
-
-
Naito, S.1
Shimizu, S.2
Maeda, S.3
Wang, J.4
Paul, R.5
Fagin, J.A.6
-
35
-
-
2542469732
-
Platelet-derived growth factor-BB and Ets-1 transcription factor negatively regulate transcription of multiple smooth muscle differentiation marker genes
-
Dandre F, Owens GK. Platelet-derived growth factor-BB and Ets-1 transcription factor negatively regulate transcription of multiple smooth muscle differentiation marker genes. Am J Physiol Heart Circ Physiol. 2004;286:H2042-H2051.
-
(2004)
Am J Physiol Heart Circ Physiol
, vol.286
-
-
Dandre, F.1
Owens, G.K.2
-
36
-
-
9144274494
-
Regulation of platelet-derived growth factor-A chain by Kruppel-like factor 5: New pathway of cooperative activation with nuclear factor-kappaB
-
Aizawa K, Suzuki T, Kada N, Ishihara A, Kawai-Kowase K, Matsumura T, Sasaki K, Munemasa Y, Manabe I, Kurabayashi M, Collins T, Nagai R. Regulation of platelet-derived growth factor-A chain by Kruppel-like factor 5: new pathway of cooperative activation with nuclear factor-kappaB. J Biol Chem. 2004;279:70-76.
-
(2004)
J Biol Chem
, vol.279
, pp. 70-76
-
-
Aizawa, K.1
Suzuki, T.2
Kada, N.3
Ishihara, A.4
Kawai-Kowase, K.5
Matsumura, T.6
Sasaki, K.7
Munemasa, Y.8
Manabe, I.9
Kurabayashi, M.10
Collins, T.11
Nagai, R.12
-
37
-
-
0042346348
-
Ets-1 protects vascular smooth muscle cells from undergoing apoptosis by activating p21WAF1/Cip1: Ets-1 regulates basal and inducible p21WAF1/Cip 1 transcription via distinct cis-acting elements in the p21WAF/Cip 1 promoter
-
Zhang C, Kavurma MM, Khachigian LM. Ets-1 protects vascular smooth muscle cells from undergoing apoptosis by activating p21WAF1/Cip1: Ets-1 regulates basal and inducible p21WAF1/Cip 1 transcription via distinct cis-acting elements in the p21WAF/Cip 1 promoter. J Biol Chem. 2003;278:27903-27909.
-
(2003)
J Biol Chem
, vol.278
, pp. 27903-27909
-
-
Zhang, C.1
Kavurma, M.M.2
Khachigian, L.M.3
-
38
-
-
0037151008
-
c-Jun regulates vascular smooth muscle cell growth and neointima formation after arterial injury: Inhibition by a novel DNAzyme targeting c-Jun
-
Khachigian LM, Fahmy RG, Zhang G, Bobryshev YV, Kaniaros A. c-Jun regulates vascular smooth muscle cell growth and neointima formation after arterial injury: inhibition by a novel DNAzyme targeting c-Jun. J Biol Chem. 2002;277:22985-22991.
-
(2002)
J Biol Chem
, vol.277
, pp. 22985-22991
-
-
Khachigian, L.M.1
Fahmy, R.G.2
Zhang, G.3
Bobryshev, Y.V.4
Kaniaros, A.5
|