Infectious response to E. coli: Molecular and genetic pathways

International Journal of Antimicrobial Agents

Volumn 24, Issue SUPPL. 1, 2004, Pages 57-60

  Schaeffer, Anthony J ^a   Klumpp, David J ^a   Weiser, Adam C ^b   Sengupta, Shomit ^c   Forrestal, Sarah G ^d   Batler, Robert A ^e  

^a NORTHWESTERN UNIVERSITY   (United States)

^b Urological Associates   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^d NORTHWESTERN UNIVERSITY   (United States)

^e METHODIST HOSPITAL   (United States)

Author keywords

Type 1 piliated E. coli; Urinary tract infection; Urothelial apoptosis

Indexed keywords

I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN;

APOPTOSIS; BACTERIUM ISOLATE; BACTERIUM PILUS; CELL LINE; CONFERENCE PAPER; CONTROLLED STUDY; ESCHERICHIA COLI; FLOW CYTOMETRY; HUMAN; HUMAN CELL; INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; REPORTER GENE; SIGNAL TRANSDUCTION; URINARY TRACT INFECTION; UROTHELIUM;

EID: 4444315942     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2004.02.011     Document Type: Conference Paper

References (12)

1. Hooton T.M., Stamm W.E. Diagnosis and treatment of uncomplicated urinary tract infection. Infect. Dis. Clin. N. Am. 11:1997;551-581
2. Fukushi Y., Irikasa S., Kagayama M. An electron microscopic study of the interaction between vesical epithelium and E. coli. Investig. Urol. 17:1979;61-68
3. Mulvey M., Lopez-Boado Y., Wilson C., et al. Induction and evasion of host defenses by type 1-piliated uropathogenic Escherichia coli. Science. 282:1998;494-497
4. Barnes P.J., Karin M. Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases. N. Engl. J. Med. 336:1997;1066-1071
5. Rothwarf DM, Karin M. The NF-κB activation pathway; a paradigm in information transfer from membrane to nucleus. Science's STKE [Online], posting date 20 October 1999. http:stke.sciencemag.org/cgi/content/full/OC_sigtrans; 1995/5/re1.
6. Wang C.Y., Mayo M.W., Korneluk R.G., Goeddel D.V., Baldwin A.S. Jr. NF-κB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science. 281:1998;1680-1683
7. Rhen M., Eriksson S., Pettersson S. Bacterial adaptation to host innate immunity responses. Curr. Opin. Microbiol. 3:2000;60-64
8. Schrum L.W., Black D., Iimuro Y., Rippe R.A., Brenner D.A., Behrns K.E. c-Jun does not mediate hepatocyte apoptosis following NF-κB inhibition and partial hepatectomy. J. Surg. Res. 88:2000;142-149
9. Orth K., Palmer L.E., Bao Z.Q., et al. Inhibition of the mitogen-activated protein kinase superfamily by a Yersinia effector. Science. 285:1999;1920-1923
10. Orth K., Xu Z., Mudgett M.B., et al. Disruption of signaling by Yersinia effector YopJ, a ubiquitin-like protein protease. Science. 290:2000;1594-1597
11. Martinez J.J., Mulvey M.A., Schilling J.D., Pinkner J.S., Hultgren S.J. Type 1 pilus-mediated bacterial invasion of bladder epithelial cells. EMBO J. 19:2000;2803-2812
12. Klumpp D.J., Weiser A.C., Sengupta S., Forrestal S.G., Batler R.A., Schaeffer A.J. Uropathogenic Escherichia coli potentiates type 1 pilus-induced apoptosis by suppressing NF-κB. Infect. Immun. 69:2001;6689-6695