Dynamic changes of mitogen-activated protein kinase signal transduction in rats with severe acute pancreatitis

Chinese Journal of Digestive Diseases

Volumn 5, Issue 3, 2004, Pages 123-125

  Ren, Hong Bo ^a   Li, Zhao Shen ^a   Xu, Guo Ming ^a   Tu, Zheng Xing ^a   Shi, Xin Gang ^a   Jia, Yi Tao ^a   Gong, Yan Fang ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

c Jun N terminal kinase; p38 mitogen activated protein kinase; Severe acute pancreatitis

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE; TAUROCHOLIC ACID;

ACUTE PANCREATITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; ENZYME ACTIVITY; LUNG; MALE; NONHUMAN; PANCREAS; PANCREAS DUCT; PATHOGENESIS; POSTOPERATIVE CARE; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ACUTE DISEASE; ANIMALS; LUNG; MALE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PANCREAS; PANCREATITIS; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION;

EID: 4444298619     PISSN: 14439611     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1443-9573.2004.00162.x     Document Type: Article

References (6)

1. Kyriakis JM, Avruch J. Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol Rev 2001; 81: 807-69.
2. Robinson M, Arcaroli J, Yum HK et al. Role of p38 MAP kinase in the development of acute lung injury. Clin Immunol 2001; 101: 211-19.
3. Jacobb MH. Mitogen-activated protein kinase pathways. Curr Opin Cell Biol 1997; 9: 180-6.
4. Adams JL, Badger AM, Kumar S et al. p38 MAP kinase: molecular target for the inhibition of pro-inflammatory cytokines. Prog Med Chem 2001; 38: 1-60.
5. Wagner ACC, Metzler W, Hofken T et al. p38 MAP kinase is expressed in the pancreas and is immediately activated following cerulein hyperstimulation. Digestion 1999; 60: 41-7.
6. Blinman TA, Gukovsky I, Mouria M et al. Activation of pancreatic acinar cells on isolation from tissue: cytokine upregulation via p38 MAP kinase. Am J Physiol Cell Physiol 2000; 279: C1993-2003.