Markers of bone remodeling predict rate of bone loss in multiple sclerosis patients treated with low dose glucocorticoids

Clinica Chimica Acta

Volumn 348, Issue 1-2, 2004, Pages 147-154

  Stepan, Jan J ^a   Havrdová, Eva ^a   Týblová, Michaela ^a   Horáková, Dana ^a   Tichá, Veronika ^a   Nováková, Iveta ^a   Zikán, Vít ^a  

^a CHARLES UNIVERSITY   (Czech Republic)

Author keywords

Biochemical markers; Collagen; Glucocorticoids; Multiple sclerosis; Osteoporosis

Indexed keywords

CARBOXY TERMINAL TELOPEPTIDE; COLLAGEN TYPE 1; GLUCOCORTICOID; OSTEOCALCIN;

ADULT; ARTICLE; BONE DENSITY; BONE REMODELING; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE MARKER; FEMALE; FEMUR; HUMAN; LONG TERM CARE; LOW DRUG DOSE; LUMBAR SPINE; MAJOR CLINICAL STUDY; MALE; MOTOR PERFORMANCE; MULTIPLE SCLEROSIS; MUSCULOSKELETAL DISEASE; OSTEOLYSIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SIDE EFFECT;

ADULT; BIOLOGICAL MARKERS; BONE REMODELING; BONE RESORPTION; DOSE-RESPONSE RELATIONSHIP, DRUG; EXERCISE; FEMALE; GLUCOCORTICOIDS; HUMANS; LINEAR MODELS; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS; POSTMENOPAUSE; PROGNOSIS;

EID: 4444297490     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cccn.2004.05.012     Document Type: Article

References (28)

1. Hassager C., Jensen S.B., Gotfredsen A., Christiansen C. The impact of measurement errors on the diagnostic value of bone mass measurements: theoretical considerations. Osteoporos Int. 1(4):1991;250-256
2. Eastell R., Colwell A., Hampton L., Reeve J. Biochemical markers of bone resorption compared with estimates of bone resorption from radiotracer kinetic studies in osteoporosis. J. Bone Miner. Res. 12(1):1997;59-65
3. Stepan J.J. Prediction of bone loss in postmenopausal women. Osteoporos Int. 11(Suppl. 6):2000;45-54
4. LoCascio V., Ballanti P., Milani S., Bertoldo F., LoCascio C., Zanolin E.M., et al. A histomorphometric long-term longitudinal study of trabecular bone loss in glucocorticoid-treated patients: prednisone versus deflazacort. Calcif. Tissue Int. 62(3):1998;199-204
5. Reid I.R. Steroid-induced osteoporosis. Osteoporos Int. 7(Suppl. 3):1997;213-216
6. Weinstein R.S., Manolagas S.C. Apoptosis and osteoporosis. Am. J. Med. 108(2):2000;153-164
7. Manolagas S.C., Weinstein R.S. New developments in the pathogenesis and treatment of steroid-induced osteoporosis. J. Bone Miner. Res. 14(7):1999;1061-1066
8. Hermus A.R., Smals A.G., Swinkels L.M., Huysmans D.A., Pieters G.F., Sweep C.F., et al. Bone mineral density and bone turnover before and after surgical cure of Cushing's syndrome. J. Clin. Endocrinol. Metab. 80(10):1995;2859-2865
9. Osella G., Terzolo M., Reimondo G., Piovesan A., Pia A., Termine A., et al. Serum markers of bone and collagen turnover in patients with Cushing's syndrome and in subjects with adrenal incidentalomas. J. Clin. Endocrinol. Metab. 82(10):1997;3303-3307
10. Weinstein R.S., Chen J.R., Powers C.C., Stewart S.A., Landes R.D., Bellido T., et al. Promotion of osteoclast survival and antagonism of bisphosphonate-induced osteoclast apoptosis by glucocorticoids. J. Clin. Invest. 109(8):2002;1041-1048
11. Leong G.M., Mercado Asis L.B., Reynolds J.C., Hill S.C., Oldfield E.H., Chrousos G.P. The effect of Cushing's disease on bone mineral density, body composition, growth, and puberty: a report of an identical adolescent twin pair. J. Clin. Endocrinol. Metab. 81(5):1996;1905-1911
12. Pearce G., Tabensky D.A., Delmas P.D., Baker H.W., Seeman E. Corticosteroid-induced bone loss in men. J. Clin. Endocrinol. Metab. 83(3):1998;801-806
13. Dempster D.W. Bone histomorphometry in glucocorticoid-induced osteoporosis. J. Bone Miner. Res. 4(2):1989;137-141
14. Delmas P.D., Eastell R., Garnero P., Seibel M.J., Stepan J. The use of biochemical markers of bone turnover in osteoporosis. Committee of Scientific Advisors of the International Osteoporosis Foundation. Osteoporos Int. 11(Suppl. 6):2000;2-17
15. Scheinberg L.C., Smith C.R. Signs and symptoms of multiple sclerosis. Scheinberg L.C., Holland N.J. Multiple sclerosis. 2nd ed.:1987;43-51 Raven Press, New York
16. Nieves J., Cosman F., Herbert J., Shen V., Lindsay R. High prevalence of vitamin D deficiency and reduced bone mass in multiple sclerosis. Neurology. 44(9):1994;1687-1692
17. Cosman F., Nieves J., Komar L., Ferrer G., Herbert J., Formica C., et al. Fracture history and bone loss in patients with MS. Neurology. 51(4):1998;1161-1165
18. Formica C.A., Cosman F., Nieves J., Herbert J., Lindsay R. Reduced bone mass and fat-free mass in women with multiple sclerosis: effects of ambulatory status and glucocorticoid use. Calcif. Tissue Int. 61(2):1997;129-133
19. Kelly R. Clinical aspects of multiple sclerosis. Koetsier J.C. Handbook of clinical neurology. 1985;49-78 Elsevier Science, New York
20. Bowen J., Gibbons L., Gianas A., Kraft G.H. Self-administered Expanded Disability Status Scale with functional system scores correlates well with a physician-administered test. Mult. Scler. 7(3):2001;201-206
21. Goodkin D.E., Cookfair D., Wende K., Bourdette D., Pullicino P., Scherokman B., et al. Inter- and intrarater scoring agreement using grades 1.0 to 3.5 of the Kurtzke Expanded Disability Status Scale (EDSS). Multiple Sclerosis Collaborative Research Group. Neurology. 42(4):1992;859-863
22. Elias A.N., Gwinup G. Immobilization osteoporosis in paraplegia. J. Am. Parapleg. Soc. 15(3):1992;163-170
23. LeBlanc A., Schneider V., Shackelford L., West S., Oganov V., Bakulin A., et al. Bone mineral and lean tissue loss after long duration spaceflight. J. Bone Miner. Res. 11(Suppl. 1):1996;S323
24. Rubin J., Murphy T.C., Fan X., Goldschmidt M., Taylor W.R. Activation of extracellular signal-regulated kinase is involved in mechanical strain inhibition of RANKL expression in bone stromal cells. J. Bone Miner. Res. 17(8):2002;1452-1460
25. Boyle W.J., Simonet W.S., Lacey D.L. Osteoclast differentiation and activation. Nature. 423(6937):2003;337-342
26. Shi X.M., Blair H.C., Yang X., McDonald J.M., Cao X. Tandem repeat of C/EBP binding sites mediates PPARgamma2 gene transcription in glucocorticoid-induced adipocyte differentiation. J. Cell Biochem. 76(3):2000;518-527
27. Doerr P., Pirke K.M. Cortisol-induced suppression of plasma testosterone in normal adult males. J. Clin. Endocrinol. Metab. 43(3):1976;622-629
28. Sakakura M., Takebe K., Nakagawa S. Inhibition of luteinizing hormone secretion induced by synthetic LRH by long-term treatment with glucocorticoids in human subjects. J. Clin. Endocrinol. Metab. 40(5):1975;774-779