Facilitation of proteasomal degradation of p27Kip1 by N-terminal cleavage and their sequence requirements

FEBS Letters

Volumn 574, Issue 1-3, 2004, Pages 111-115

  Hirano, Katsuya ^a   Ihara, Eikichi ^a   Hirano, Mayumi ^a   Nishimura, Junji ^a   Nawata, Hajime ^a,b   Kanaide, Hideo ^a,b  

^a KYUSHU UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

ATP S, a non hydrolysable ATP analogue; Cdk, cyclin dependent kinase; p27Kip1; Proteasome; Proteolysis

Indexed keywords

ADENOSINE TRIPHOSPHATE; CARBON; NITROGEN; PROTEASOME; PROTEASOME INHIBITOR; PROTEIN; PROTEIN KIP1; PROTEIN P27; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION;

ANIMALS; CARRIER PROTEINS; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYSTEINE ENDOPEPTIDASES; HELA CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MULTIENZYME COMPLEXES; MUTAGENESIS, SITE-DIRECTED; PROTEASE INHIBITORS; PROTEASOME ENDOPEPTIDASE COMPLEX; RECOMBINANT PROTEINS; SWINE;

EID: 4444282575     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2004.08.014     Document Type: Article

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