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Volumn 38, Issue 12, 2003, Pages 962-965

Synthesis of prodrugs of tacrine hydrochloride and evaluation of the stability and biodistribution in mice

Author keywords

Biodistribution; Blood brain barrier; Drug delivery system; Prodrug; Tacrine hydrochloride

Indexed keywords

CHOLINESTERASE INHIBITOR; DRUG DERIVATIVE; N BUTYRAMIDE TACRINE; N-BUTYRAMIDE-TACRINE; PRODRUG; TACRINE;

EID: 4444279139     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (1)

References (7)
  • 1
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    • Reconstitution of the blood-brain barrier in cell culture for studies of drug transport and metabolism [J]
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    • (1996) Acta Drug Del Rev , vol.22 , Issue.1 , pp. 251-264
    • Boer, A.G.1    Breimer, D.D.2
  • 2
    • 0028922858 scopus 로고
    • Tacrine [J]
    • Kenneth LD, Powchik P. Tacrine [J]. Lancet, 1995, 345 (11):625-627.
    • (1995) Lancet , vol.345 , Issue.11 , pp. 625-627
    • Kenneth, L.D.1    Powchik, P.2
  • 3
    • 0028316959 scopus 로고
    • Hepatotoxic effects of tacrine administration in patients with Alzheimer's disease [J]
    • Watkins PB, Zimmerman HJ, Margaret JK, et al. Hepatotoxic effects of tacrine administration in patients with Alzheimer's disease [J]. J Am Med Assoc, 1994, 271(6): 992-998.
    • (1994) J Am Med Assoc , vol.271 , Issue.6 , pp. 992-998
    • Watkins, P.B.1    Zimmerman, H.J.2    Margaret, J.K.3
  • 4
    • 12444280057 scopus 로고    scopus 로고
    • Synthesis of the prodrug of 4-aminotetrahydroacridine [J]
    • Jiang Y, Zhang ZR, Wu Y, et al. Synthesis of the prodrug of 4-aminotetrahydroacridine [J]. West Chin J Pharm Sci, 2002, 17(1):35-36.
    • (2002) West Chin J Pharm Sci , vol.17 , Issue.1 , pp. 35-36
    • Jiang, Y.1    Zhang, Z.R.2    Wu, Y.3
  • 7
    • 0032493853 scopus 로고    scopus 로고
    • Determination of tacrine and its metabolites in human plasma and urine by high-preformance liquid chromatography and fluorescence detection [J]
    • Hansen LL, Larsen K, Brosen K. Determination of tacrine and its metabolites in human plasma and urine by high-preformance liquid chromatography and fluorescence detection [J]. J Chromatogr B, 1998, 712(1-2):183-187.
    • (1998) J Chromatogr B , vol.712 , Issue.1-2 , pp. 183-187
    • Hansen, L.L.1    Larsen, K.2    Brosen, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.