Hydrolysis kinetics and photolysis kinetics of N1-retinoyl-5-fluorouracil

S.T.P. Pharma Sciences

Volumn 11, Issue 3, 2001, Pages 243-246

  Zhang, Z R ^a   Luo, W Z ^a   Nagai, T ^a  

^a HOSHI UNIVERSITY   (Japan)

Author keywords

5 Fluorouracil; Hydrolysis kinetics; N1 retinoyl 5 fluorouracil; Photolysis kinetics; Prodrug

Indexed keywords

FLUOROURACIL DERIVATIVE; N1 RETINOYL 5 FLUOROURACIL; OCTANOL; PRODRUG; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; CATALYSIS; DRUG HYDROLYSIS; DRUG SOLUBILITY; DRUG STABILITY; LIPOPHILICITY; PARTITION COEFFICIENT; PHOTOLYSIS; PHOTOSENSITIVITY;

EID: 0034960913     PISSN: 11571489     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Enhanced potency of 9-cis versus all-atranretinoic acid to induce the differentiation of human neuroblastoma cell
2. Nucleic acid related compound. 37. Convenient and high-yield syntheses of N-[(2-hydroxy-ethoxy)methyl] heterocycles as 'acyclic nucleoside' analogues
3. Synthesis and biological evaluation of prodrugs of zidovudine
4. Prodrugs of 5-fluorouracil. II. Hydrolysis kinetics, bioactivation, solubility and lipophilicity of N-alkoxycarbonyl derivatives of 5-fluorouracil
5. The ionisation constant of water and the dissociation of water in potassium chloride solutions from electromotive forces of cells without liquid junctions
6. Prodrugs of 5-fluorouracil. I. Hydrolysis kinetics and physicochemical properties of various N-acyl derivatives of 5-fluorouracil
7. Prodrugs of 5-fluorouracil. III. Hydrolysis kinetics in aqueous solution and biological media, lipophilicity and solubility of various 1-carbamoyl derivatives of 5-fluorouracil
8. Prodrugs of 5-fluorouracil. IV. Hydrolysis kinetics, bioactivation and physicochemical properties of N-acyloxymethyl derivatives of 5-fluorouracil