A model of the oscillatory metabolism of activated neutrophils

Biophysical Journal

Volumn 84, Issue 1, 2003, Pages 69-81

  Olsen, Lars F ^a,b   Kummer, Ursula ^a   Kindzelskii, Andrei L ^c   Petty, Howard R ^c  

^a European Media Laboratory   (Germany)

^b UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^c WAYNE STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 AMINONICOTINAMIDE; CELL MEMBRANE PROTEIN; DEXAMETHASONE; DIPHENYLIODONIUM SALT; ENZYME INHIBITOR; GLUCOSE 6 PHOSPHATE DEHYDROGENASE INHIBITOR; HEXOSE PHOSPHATE; MYELOPEROXIDASE; OXYGEN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CELL TRANSPORT; COMPARTMENT MODEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; HEXOSE MONOPHOSPHATE SHUNT; HUMAN; HUMAN CELL; LEUKOCYTE ACTIVATION; LEUKOCYTE METABOLISM; NEUTROPHIL; OSCILLATION; PHAGOSOME; PREDICTION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT;

EID: 0037216933     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(03)74833-4     Document Type: Article

References (53)

1. Aas, V., K. Larsen, and J. G. Iversen. 1998. IFN-gamma induces calcium entry in human neutrophils. J. Interferon Cytokine Res. 18:197-205.
2. Aas, V., K. Larsen, and L. G. Iversen. 1999. Interferon-gamma elicits a G-protein-dependent Ca2+ signal in human neutrophils after depletion of intracellular Ca2+ stores. Cell. Sign. 11:101-110.
3. Adachi, Y., A. L. Kindzelskii, N. Ohno, T. Yadomae, and H. R. Petty. 1999. Amplitude and frequency modulation of metabolic signals in leukocytes: Synergistic role in interferon-γ in interleukin-6 and interleukin-2-mediated cell activation. J. Immunol. 163:4367-4374.
4. Allegra, M., P. G. Furtmüller, G. Regelsberger, M. L. Turco-Liveri, L. Tesoriere, M Peretti, M. A. Livrea, and C. Obinger. 2001. Mechanism of the reaction of melatonin with human myeloperoxidase. Biochem. Biophys. Res. Commun. 282:380-386.
5. Amit, A., A. L. Kindzelskii, J. Zanoni, J. N. Jarvis, and H. R. Petty. 1999. Complement deposition on immune complexes reduces the frequencies of metabolic, proteolytic, and superoxide oscillations of migrating neutrophils. Cell. Immunol. 194:47-53.
6. 2 and production of oxygen by horseradish peroxidase. Arch. Biochem. Biophys. 382:232-237.
7. Bender, J. G., and D. E. Van Epps. 1985. Inhibition of human neutrophil function by 6-aminonicotinamide: The role of the hexose monophosphate shunt in cell activation. Immunopharm. 10:191-199.
8. Berton, G., L. Zeni, M. A. Cassatella, and F. Rossi. 1986. Gamma interferon is able to enhance the oxidative metabolism of human neutrophils. Biochem. Biophys. Res. Commun. 138:1276-1282.
9. Bronnikova, T. V., V. R. Fed'kina, W. M. Schaffer, and L. F. Olsen. 1995. Period-doubling bifurcations and chaos in a detailed model of the peroxidase-oxidase reaction. J. Phys. Chem. 99:9309-9312.
10. Collison, K., S. Saleh, R. Parhar, B. Meyer, A. Kwaasi, K. Al-Hussein, S. Al-Sedairy, and F. Al-Mohanna. 1998. Evidence that IL-12-activated Ca2+ and tyrosine signaling pathways in human neutrophils. J. Immunol. 161:3737-3745.
11. Costa, E. J. X., R. H. Lopes, and M. T. Lamy-Freund. 1995. Permeability of pure lipid bilayers to melatonin. J. Pineal Res. 19:123-126.
12. Cross, A. R., and O. T. G. Jones. 1986. The effect of the inhibitor diphenylene iodonium on the superoxide-generating system of neutrophils. Biochem. J. 237:111-116.
13. Demaurex, N., G. P. Downey, T. K. Waddell, and S. Grinstein. 1996. Intracellular pH regulation during spreading of human neutrophils. J. Cell Biol. 133:1391-1402.
14. Dunford, H. B. 1999. Heme Peroxidases. John Wiley & Sons, New York.
15. Finocchiaro, L. M. E., E. S. Arzt, S. Fernandez-Castelo, M. Criscuolo, S. Finkielman, and V. E. Nahmod. 1988. Serotonin and melatonin synthesis in peripheral blood mononuclear cells: Stimulation by interferon-γ as part of an immunomodulatory pathway. J. Interferon Res. 8:705-716.
16. Finocchiaro, L. M. E., V. E. Nahmod, and J. M. Launay. 1991. Melatonin biosynthesis and metabolism in peripheral-blood mononuclear leukocytes. Biochem. J. 280:727-731.
17. Fujimoto, S., N. Kawakami, and N. Ohara. 1993. Formation of hydroxyl radical by the myeloperoxidase NADH oxygen system. Biol. Pharm. Bull. 16:525-528.
18. Furtmüller, P. G., C. Obinger, Y. Hsuanyu, and H. B. Dunford. 2000. Mechanism of reaction of myeloperoxidase with hydrogen peroxide and chloride ion. Eur. J. Biochem. 267:5858-5864.
19. Ginis, I., and A. I. Tauber. 1990. Activation mechanisms of adherent human neutrophils. Blood. 76:1233-1239.
20. Hampton, M. B., A. J. Kettle, and C. C. Winterbourn. 1998. Inside the neutrophil phagosome: Oxidants, myeloperoxidase, and bacterial killing. Blood. 92:3007-3017.
21. Hauser, M. J. B., and L. F. Olsen. 1998. The role of naturally occurring phenols in inducing oscillations in the peroxidase-oxidase reaction. Biochemistry. 37:2458-2469.
22. Henderson, L. M., and J. B. Chappell. 1996. NADPH oxidase of neutrophils. Biochim. Biophys. Acta. 1273:87-107.
23. 2 across water channels. J. Exp. Bot. 51:2053-2066.
24. Jones, R. D., J. T. Hancock, and A. H. Morice. 2000. NADPH oxidase: A universal oxygen sensor? Free Radic. Biol. Med. 29:416-424.
25. Kindzelskii, A. L., M. J. Zhou, R. P. Haugland, and H. R. Petty. 1998. Oscillatory pericellular proteolysis and oxidant deposition during neutrophil migration. Biophys. J. 74:90-97.
26. Kindzelskii, A. L., and H. R. Petty. 2000. Extremely low frequency electric fields promote neutrophil extension, metabolic resonance and DNA damage during migration. Biochim. Biophys. Acta. 1495:90-111.
27. Kirkor, E. S., and A. Scheeline. 2000. Nicotinamide adenine dinucleotide species in the horseradish peroxidase-oxidase oscillator. Eur. J. Biochem. 267:5014-5022.
28. Klebanoff, S. J. 1991. Myeloperoxidase: Occurrence and biological function. In Peroxidases in Chemistry and Biology. J. Everse, K. E. Everse and M. B. Grisham, editors. CRC Press, Boca Raton, FL. 1-35.
29. Kummer, U., M. J. B. Hauser, K. Wegmann, L. F. Olsen, and G. Baier. 1997. Oscillations and complex dynamics in the peroxidase-oxidase reaction induced by naturally occurring aromatic substrates. J. Am. Chem. Soc. 119:2084-2087.
30. Levy, R., O. Nagauker, E. Sikuler, T. L. Leto, and F. Schlaeffer. 1994. Elevated NADPH-oxidase activity in neutrophils from bile-duct-ligated rats; changes in the kinetic parameters and in the oxidase cytosolic factor p47. Biochim. Biophys. Acta. 1220:261-265.
31. MacDonald, R. C., R. I. MacDonald, B. P. Menco, K. Takeshita, N. K. Subbarao, and L. R. Hu. 1991. Small-volume extrusion apparatus for preparation of large unilamellar vesicles. Biochim. Biophys. Acta. 1061:297-303.
32. Matuszak, Z., K. Reszka, and C. F. Chignell. 1997. Reaction of melatonin and related indoles with hydroxyl radicals: EPR and spin trapping investigations. Free Rad. Biol. Med. 23:367-372.
33. McCord, J. M. 2000. The evolution of free radicals and oxidative stress. Am. J. Med. 108:652-659.
34. Mohan, R. F., and M. S. Jacobson. 1993. Inhibition of macrophage superoxide generation by dehydroepiandrosterone. Am. J. Med. Sci. 306:10-15.
35. Morrey, K. M., J. A. McLachlan, C. D. Serkin, and O. Bakouche. 1994. Activation of human monocytes by the pineal hormone melatonin. J. Immunol. 153:2671-2680.
36. 2-system. Nature. 222:794.
37. Oehler, R., G. Weingartmann, N. Manhart, U. Salzer, M. Meissner, W. Schlegel, A. Spittler, M. Bergmann, D. Kandioler, S. Oismuller, H. M. Struse, and E. Roth. 2000. Polytrauma induces increased expression of pyruvate kinase in neutrophils. Blood. 95:1086-1092.
38. Olsen, L. F., A. Lunding, F. R. Lauritsen, and M. Allegra. 2001. Melatonin activates the peroxidase-oxidase reaction and promotes oscillations. Biochem. Biophys. Res. Commun. 284:1071-1076.
39. Petty, H. R., R. G. Worth, and A. L. Kindzelskii. 2000. Imaging sustained dissipative patterns in the metabolism of individual living cells. Phys. Rev. Lett. 84:2754-2757.
40. Petty, H. R. 2001. Neutrophil oscillations: Temporal and spatiotemporal aspects of cell behavior. Immunol. Res. 23:85-94.
41. Recchioni, R., F. Marcheselli, F. Moroni, R. Gaspar, S. Damjanovich, and C. Pieri. 1998. Melatonin increases the intensity of respiratory burst and prevents L-selectin shedding in human neutrophils in vitro. Biochem. Biophys. Res. Commun. 252:20-24.
42. Rom, W. N., and T. Harkin. 1991. Dehydroepiandrosterone inhibits the spontaneous release of superoxide radical by alveolar macrophages in vitro in asbestosis. Environ. Res. 55:145-156.
43. Rosenspire, A. J., A. L. Kindzelskii, and H. R. Petty. 2000. Interferon-γ and sinusoidal electric fields signal by modulating NAD(P)H oscillations in polarized neutrophils. Biophys. J. 79:3001-3008.
44. Scheeline, A., D. L. Olson, E. P. Williksen, G. A. Horras, M. L. Klein, and R. Larter. 1997. The peroxidase-oxidase oscillator and its constituent chemistries. Chem. Rev. 97:739-756.
45. Sevcik, P., and H. B. Dunford. 1991. Kinetics of the oxidation of NADH by methylene blue in a closed system. J. Phys. Chem. 95:2411-2415.
46. Silva, S. O., V. F. Ximenes, L. H. Catalani, and A. Campa. 2000. Myeloperoxidase-catalyzed oxidation of melatonin by activated neutrophils. Biochem. Biophys. Res. Commun. 279:657-662.
47. Sørensen, O., and N. Borregaard. 1999. Methods for quantitation of human neutrophil proteins: A survey. J. Immunol. Methods. 232:179-190.
48. Tauber, A. I. 1987. Protein kinase C and the activation of the human neutrophil NADPH oxidase. Blood. 69:711-720.
49. Tyagi, S. R., M. Tamura, D. N. Burnham, and J. D. Lambeth. 1988. Phorbol myristate acetate (PMA) augments chemoattractant-induced diglyceride generation in human neutrophils but inhibits phosphoinositide hydrolysis. Implications for the mechanism of PMA priming of the respiratory burst. J. Biol. Chem. 263:13191-13198.
50. Whitcomb, J. M., and A. G. Schwartz. 1985. Dehydroepiandrosterone and 16 alpha-Br-epiandrosterone inhibit 12-0-tetracanolyphorbol-13-acetate stimulation of superoxide radical production by human polymorphonuclear leukocytes. Carcinogen. 6:333-335.
51. White, A., P. Handler, E. L. Smith, R. L. Hill, and I. R. Lehman. 1978. Principles of Biochemistry. McGraw-Hill, New York.
52. Ximenes, V. F., L. H. Catalani, and A. Campa. 2001. Oxidation of melatonin and tryptophan by an HRP cycle involving compound III. Biochem. Biophys. Res. Commun. 298:130-134.
53. Zhang, H., G. Squadrito, and W. A. Pryor. 1998. The reaction of melatonin with peroxynitrite: Formation of melatonin radical cation and absence of stable nitrated products. Biochem. Biophys. Res. Commun. 251:83-87.