Prophylactic efficacy of ophthalmic quinolones in experimental endophthalmitis in rabbits

Journal of Ocular Pharmacology and Therapeutics

Volumn 24, Issue 3, 2008, Pages 278-289

  Wada, Tomoyuki ^a   Kozai, Seiko ^a   Tajika, Tetsuya ^a   Sakaki, Hideyuki ^a   Suzuki, Takashi ^b   Ohashi, Yuichi ^b  

^a SENJU PHARMACEUTICAL CO LTD   (Japan)

^b EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GATIFLOXACIN; OFLOXACIN; QUINOLONE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTERIOR EYE CHAMBER; AQUEOUS HUMOR; AREA UNDER THE CURVE; ARTICLE; BACTERIAL COUNT; COLONY FORMING UNIT; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG ABSORPTION; DRUG EFFICACY; ENDOPHTHALMITIS; ENTEROCOCCUS FAECALIS; MALE; MAXIMUM PLASMA CONCENTRATION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PROPHYLAXIS; RABBIT; SLIT LAMP;

ANIMALS; ANTERIOR CHAMBER; ANTI-BACTERIAL AGENTS; BIOLOGICAL AVAILABILITY; DISEASE PROGRESSION; ENDOPHTHALMITIS; ENTEROCOCCUS FAECALIS; EYE; FLUOROQUINOLONES; GRAM-POSITIVE BACTERIAL INFECTIONS; MALE; OFLOXACIN; OINTMENTS; OPHTHALMIC SOLUTIONS; QUINOLONES; RABBITS;

EID: 44349164417     PISSN: 10807683     EISSN: None     Source Type: Journal    
DOI: 10.1089/jop.2007.0121     Document Type: Article

References (39)

1. Kamalarajah, S., Silvestri, G., Sharma, N., et al. Surveillance of endophthalmitis following cataract surgery in the UK. Eye 18:580-587, 2004.
2. Miller, J.J., Scott, I.U., Flynn, H.W., Jr., et al. Acute-onset endophthalmitis after cataract surgery (2000-2004): Incidence, clinical settings, and visual acuity outcomes after treatment. Am. J. Ophthalmol. 139:983-987, 2005.
3. Nagaki, Y., Hayasaka, S., Kadoi, C., et al. Bacterial endophthalmitis after small-incision cataract surgery. Effect of incision placement and intraocular lens type. J. Cataract Refract. Surg. 29:20-26, 2003.
4. Patwardhan, A., Rao, G.P., Saha, K., et al. Incidence and outcomes evaluation of endophthalmitis management after phacoemulsification and 3-piece silicone intraocular lens implantation over 6 years in a single eye unit. J. Cataract Refract. Surg. 32:1018-1021, 2006.
5. Wong, T.Y., and Chee, S.P. The epidemiology of acute endophthalmitis after cataract surgery in an Asian population. Ophthalmology 111:699-705, 2004.
6. Hara, J. [Relation between causative organism and inflammation onset in pseudophakic endophthalmitis following cataract surgery]. [Japanese] Atarashii Ganka (Journal of the Eye) 20:657-660, 2003.
7. Jensen, M.K., Fiscella, R.G., Crandall, A.S., et al. A retrospective study of endophthalmitis rates comparing quinolone antibiotics. Am. J. Ophthalmol. 139:141-148, 2005.
8. The Endophthalmitis Vitrectomy Study Group. Microbiologic factors and visual outcome in the Endophthalmitis Vitrectomy Study. Am. J. Ophthalmol. 122:830-846, 1996.
9. Scott, I.U., Loo, R.H., Flynn, H.W., Jr., et al. Endophthalmitis caused by Enterococcus faecalis: antibiotic selection and treatment outcomes. Ophthalmology 110: 1573-1577, 2003.
10. Speaker, M.G., Milch, F.A., Shah, M.K., et al. Role of external bacterial flora in the pathogenesis of acute postoperative endophthalmitis. Ophthalmology 98: 639-650, 1991.
11. Ciulla, T.A., Starr, M.B., and Masket, S. Bacterial endophthalmitis prophylaxis for cataract surgery: An evidence-based update. Ophthalmology 109:13-24, 2002.
12. Speaker, M.G., and Menikoff, J.A. Prophylaxis of endophthalmitis with topical povidone-iodine. Ophthalmology 98:1769-1775, 1991.
13. Ariyasu, R.G., Nakamura, T., Trousdale, M.D., et al. Intraoperative bacterial contamination of the aqueous humor. Ophthalmic Surg. 24:367-374, 1993.
14. Mistlberger, A., Ruckhofer, J., Raithel, E., et al. Anterior chamber contamination during cataract surgery with intraocular lens implantation. J. Cataract Refract. Surg. 23:1064-1069, 1997.
15. Hosaka, M., Yasue, T., Fukuda, H., et al. In vitro and in vivo antibacterial activities of AM-1155, a new 6-fluoro-8-methoxy quinolone. Antimicrob. Agents Chemother. 36:2108-2117, 1992.
16. Wakabayashi, E., and Mitsuhashi, S. In vitro antibacterial activity of AM-1155, a novel 6-fluoro-8-methoxy quinolone. Antimicrob. Agents Chemother. 38:594-601, 1994.
17. Wada, T., Sakaki, H., and Hatano, H. [Gatifloxacin ophthalmic solution for experimental Enterococcus faecalis endophthalmitis in rabbits]. [Japanese] Atarashii Ganka (Journal of the Eye) 21:1525-1529, 2004.
18. Uno, T., Hatano, H., and Ohashi, Y. [Antibacterial activity of gatifloxacin against ocular clinical isolates]. [Japanese] Atarashii Ganka (Journal of the Eye) 21:1547-1553, 2004.
19. Fung-Tomc, J., Minassian, B., Kolek, B., et al. In vitro antibacterial spectrum of a new broad-spectrum 8-methoxy fluoroquinolone, gatifloxacin. J. Antimicrob. Chemother. 45:437-446, 2000.
20. Mather, R., Karenchak, L.M., Romanowski, E.G., et al. Fourth-generation fluoroquinolones: New weapons in the arsenal of ophthalmic antibiotics. Am. J. Ophthalmol. 133:463-466, 2002.
21. Callegan, M.C., Engelbert, M., Parke, D.W., 2nd, et al. Bacterial endophthalmitis: Epidemiology, therapeutics, and bacterium-host interactions. Clin. Microbiol. Rev. 15:111-124, 2002.
22. Badenoch, P.R., McDonald, P.J., and Coster, D.J. Effect of inflammation on antibiotic penetration into the anterior segment of the rat eye. Invest. Ophthalmol. Vis. Sci. 27:958-965, 1986.
23. Oztürk, F., Kurt, E., Inan, U.U., et al. Penetration of topical and oral ofloxacin into the aqueous and vitreous humor of inflamed rabbit eyes. Int. J. Pharm. 204:91-95, 2000.
24. Hardberger, R., Hanna, C., and Boyd, C.M. Effects of drug vehicles on ocular contact time. Arch. Ophthalmol. 93:42-45, 1975.
25. Hardberger, R.E., Hanna, C., and Goodart, R. Effects of drug vehicles on ocular uptake of tetracycline. Am. J. Ophthalmol. 80:133-138, 1975.
26. Freeman, D.J., Sheth, N.V., and Spruance, S.L. Failure of topical acyclovir in ointment to penetrate human skin. Antimicrob. Agents Chemother. 29:730-732, 1986.
27. Tang-Liu, D., Lambert, J., Blancaflor, S., et al. Availability of 0.3% ofloxacin ointment and solution in human conjunctiva and aqueous humor. J. Ocul. Pharm. Ther. 11:57-63, 1995.
28. max)]. [Japanese] Atarashii Ganka (Journal of the Eye) 21:1109-1112, 2004.
29. Firsov, A. A., Shevchenko, A.A., Vostrov, S.N., et al. Inter- and intraquinolone predictors of antimicrobial effect in an in vitro dynamic model: New insight into a widely used concept. Antimicrob. Agents Chemother. 42:659-665, 1998.
30. Firsov, A.A., Vostrov, S.N., Shevchenko, A.A., et al. MIC-based interspecies prediction of the antimicrobial effects of ciprofloxacin on bacteria of different susceptibilities in an in vitro dynamic model. Antimicrob. Agents Chemother. 42:2848-2852, 1998.
31. Wright, D.H., Brown, G.H., Peterson, M.L., et al. Application of fluoroquinolone pharmacodynamics. J. Antimicrob. Chemother. 46:669-683, 2000.
32. Vogelman, B., Gudmundsson, S., Leggett, J., et al. Correlation of antimicrobial pharmacokinetic parameters with therapeutic efficacy in an animal model. J. Infect. Dis. 158:831-847, 1988.
33. Herrygers, L.A., Noecker, R.J., Lane, L.C., et al. Comparison of corneal surface effects of gatifloxacin and moxifloxacin using intensive and prolonged dosing protocols. Cornea 24:66-71, 2005.
34. Price, M.O., Price, F.W., Jr., and Maclellan, D. Effect of gatifloxacin 0.3% and moxifloxacin 0.5% ophthalmic solutions on human corneal epithelium following 2 dosing regimens. J. Cataract Refract. Surg. 31:2137-2141, 2005.
35. Meredith, T.A., Trabelsi, A., Miller, M.J., et al. Spontaneous sterilization in experimental Staphylococcus epidermidis endophthalmitis. Invest. Ophthalmol. Vis. Sci. 31:181-186, 1990.
36. Jett, B.D., Jensen, H.G., Atkuri, R.V., et al. Evaluation of therapeutic measures for treating endophthalmitis caused by isogenic toxin-producing and toxin-nonproducing Enterococcus faecalis strains. Invest. Ophthalmol. Vis. Sci. 36:9-15, 1995.
37. Park, S.S., Samiy, N., Ruoff, K., et al. Effect of intravitreal dexamethasone in treatment of pneumococcal endophthalmitis in rabbits. Arch. Ophthalmol. 113: 1324-1329, 1995.
38. Wada, T., Kida, T., Inoue, T., et al. Immunomodulatory effect of gatifloxacin on mouse peritoneal macrophages in vitro and in models of endotoxin-induced rat conjunctivitis and rabbit bacterial keratitis. Ophthalmic Res. 40:54-60, 2008.
39. Dalhoff, A., and Shalit, I. Immunomodulatory effects of quinolones. Lancet Infect. Dis. 3:359-371, 2003.