Penetration of topical and oral ofloxacin into the aqueous and vitreous humor of inflamed rabbit eyes

International Journal of Pharmaceutics

Volumn 204, Issue 1-2, 2000, Pages 91-95

  Öztürk, Faruk ^a,d   Kurt, Emin ^b   Inan, Ümit Übeyt ^a   Kortunay, Selim ^c   Ilker, Süleyman Sami ^b   Başci, Nursabah E ^c   Bozkurt, Atila ^c  

^a AFYON KOCATEPE UNIVERSITY   (Turkey)

^b CELAL BAYAR UNIVERSITY   (Turkey)

^c HACETTEPE UNIVERSITY   (Turkey)

^d Dumlupinar Mh Cevat Şakir Cd ^*  (Turkey)

Author keywords

Ocular penetration; Ofloxacin; Post traumatic endophthalmitis

Indexed keywords

OFLOXACIN;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; AQUEOUS HUMOR; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG PENETRATION; ENDOPHTHALMITIS; EYE INFLAMMATION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; RABBIT; VITREOUS BODY;

ADMINISTRATION, TOPICAL; ANIMAL; ANTI-INFECTIVE AGENTS, FLUOROQUINOLONE; AQUEOUS HUMOR; ENDOPHTHALMITIS; FEMALE; MALE; OFLOXACIN; RABBITS; STAPHYLOCOCCUS AUREUS; VITREOUS BODY;

EID: 0034690969     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(00)00482-8     Document Type: Article

References (24)

1. Importance of the non-corneal absorption route in topical ophthalmic drug delivery
2. The effect of trauma on the ocular penetration of intravenous ciprofloxacin
3. In vitro activity of newer quinolones against aerobic bacteria
4. Determination of ofloxacin in human aqueous humor by HPLC with fluorescence detection
5. Penetration of ofloxacin in human aqueous and vitreous humors following oral and topical administration
6. Method of production and natural history of experimental posterior penetrating eye injury in the rhesus monkey
7. Intravenous antibiotics for endophthalmitis
8. Intracorneal, aqueous humor and vitreous humor penetration of topical and oral ofloxacin
9. Ofloxacin penetration into the eye after intravenous and topical administration
10. Effect of inflammation on intraocular penetration of intravenous ofloxacin in albino rabbits
11. Comparative pharmacokinetics of ciprofloxacin, ofloxacin and perfloxacin in human aqueous humour
12. Vitreous cefazolin levels intravenous injection: Effects of inflammation, repeated antibiotic doses, and surgery
13. Vitreous cavity penetration of ceftazidime after intravenous administration
14. Ofloxacin: A review of its antibacterial activity, pharmacokinetic properties and therapeutic use
15. A study of the intraocular diffusion of ofloxacin in humans and rabbits
16. Human sclera: Thickness and surface area
17. The comparative in vitro activity of ofloxacin and selected ophthalmic agents against ocular bacterial isolates
18. The effect of long-term use and inflammation on the ocular penetration of topical ofloxacin
19. Ofloxacin levels after intravitreal injection. Effects of trauma and inflammation
20. Postoperative endophthalmitis: A comparison of methods for treatment and prophylaxis with gentamicin
21. Ofloxacin. A reappraisal of its antimicrobial activity, pharmacology and therapeutic use
22. Penetration of gentamicin and ofloxacin in human vitreous after systemic administration
23. Aqueous humor penetration of ofloxacin given by various routes
24. Transfer of ofloxacin eye drops into anterior aqueous humor: Preventive effect of postoperative infections